Tgro039484.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tachina grossa
Gene Symbol
Bcl11b
Assembly
GCA_949987645.1
Location
OX465277.1:148581608-148597534[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.00013 0.017 17.1 0.2 2 23 265 286 264 286 0.96
2 20 0.069 8.9 8.5 3.7 1 23 291 314 291 314 0.97
3 20 0.19 25 7.1 2.9 2 23 345 366 344 366 0.96
4 20 0.0038 0.48 12.5 0.7 1 23 443 466 443 466 0.97
5 20 0.057 7.4 8.8 1.9 2 23 474 495 473 495 0.97
6 20 0.007 0.9 11.6 0.2 2 20 555 573 554 576 0.94
7 20 0.0079 1 11.5 1.6 1 23 645 668 645 668 0.92
8 20 0.0034 0.43 12.6 0.5 1 22 675 696 675 696 0.96
9 20 0.032 4.1 9.6 5.0 2 23 770 791 769 791 0.94
10 20 0.087 11 8.2 6.5 1 23 852 875 852 875 0.97
11 20 0.0053 0.68 12.0 0.9 1 23 912 935 912 935 0.97
12 20 2.6 3.3e+02 3.6 1.9 2 23 990 1010 988 1010 0.90
13 20 8.1e-06 0.001 20.9 1.5 1 23 1016 1038 1016 1038 0.98
14 20 0.0019 0.24 13.4 2.3 1 23 1044 1066 1044 1066 0.98
15 20 0.082 11 8.3 3.6 1 21 1072 1092 1072 1094 0.94
16 20 7.3e-05 0.0094 17.9 0.1 3 23 1123 1143 1122 1143 0.98
17 20 0.0013 0.17 13.9 1.9 1 23 1149 1171 1149 1171 0.98
18 20 2.7e-07 3.5e-05 25.5 0.6 1 23 1177 1199 1177 1199 0.99
19 20 0.00055 0.07 15.1 4.6 1 23 1205 1227 1205 1227 0.96
20 20 0.059 7.5 8.7 2.3 1 21 1233 1253 1233 1257 0.89

Sequence Information

Coding Sequence
ATGACGAATGAGTGTTTTATTAATGGAGTGCAGTATAAATGCCGCACTTGCTTTGATCCAGGAGCAACAGTATATCCTGTTGCAGAGGAGTGCAGCAACTCTATAACTTGGCGAGATTTATTGACTGATATTGTTAAGTTAAAGACAAACGACGACGAGTTACTTCCAAAGACCATTTGTTCGAAATGTTTGGAGAAACTTATCAGTTACTACGATTTTATACTTCATGTTCAAAATGTGAATGAAAAGTACCAGCAGCTTTTAGCAAGTGGCAAGCATTCCCCACAAAATAATAGTCTTGCCAGCAGCTCTAAGAATACAGCCGAGTTCTTGGCAGTATCTGCCACTACATTGCCTTTGGGTCAGTGTGTTCCCGAAATTAAGTTTGAAGACGAGCGCCTTATTCCTTACGATATTGTTTTGAATAACAACAGTAGAAGAAAAGATGCGGTAAAAGAAGATAATTGTGAACCTTTTATGGAAACTTTGGAAGAGGATGTTGAGCTCGCTTTAGATATGTTGCAATACCAACAGAGatCTCAAAACCAAGAAAATCGAATTCTTGAAGATGATATTAATGATTATAATTCTGATAACAGctCTACATGTGCGGACGAGAGCGAGTATCTAAATGGAAAAAGAGAGGAGAGAAAAAATAAAGTGAATGAGAACGGgTCCTCATCCTCCAGTAGTGCAAGTGAACATCACCTGCCCACTAGtCAGCCATTCGAAAAGAAAACTGAAGACCAATTCTGCAAATACTTTCCAATCGAAAAATTCAACAAACATTTAGTGTGTGGGGTATGcaagaaattattttcttcGCCGTCAGCTTATCGCAGGCATATCACGATGCACCAAGGTAAATCGTACATATGTGCATTTTGCGATCACCATGCGGAATCTAAAAGTTACTTAATTCGACATCTTAAACGTAAACATCCAGACGAATCATTTAAATCCAATGCGAAGCAAATAGCTAGCATGTTTGGGGAACGTCTGTATAGCAAACCTCTTGAATTACCACGAGTTGAATGTAAGCTGTGTTGTACTACttttgtaactaaaaaaaaacttcttcaGCATCTAGAGAGCCATAGTGATGTTAGTACTCTAGACAGTTTACAATTAAGCAGTGATATTATTCAGCGTTGGTTTCCAAATAAGAGAAATTTGCAAGTTATAAAAACAATGATATGTAAAGACATTAGCGAAAAAAACTGGATCAAAtattatacaattttaaatgatttttcctatGAAATATCCATTAGTGATACGGATGCAGAAGATTTGGAAGAAGAAACAGAAGCACCTGCCAGCAAATATAAATGCGAATTGTGTGGAaaagattttttgtataaatatcaAGTGTTTGCTCACTTGAGAGAGGATCATTTGAACGAAAAAATTCCTTGGAAATGCAGCCATTGCAATCTGGAATTTATAtcaataaaaatgtatgaactACATAAACAAACCCACTGCCTGTCTAAACATAAACTACTACATTGTCCCAATTGCAATGGCAAGTTTGTCTGGCTcgtaaatatgaaaaaacacaATTGTGTTACGAAAATATTGGATATTGAGAAACcttttaatgttaaaataaatgagACTTGCAATGATGAAATGCGTTCATCGCCAGAAACTATCATAAAATGTGGTCTTTGTGACATGACCTTTGAAAAACTGCGCGATTTACGACAACACATGCCCTTGCACGCCGATGGCAAAACTGGAGTTGATTTTAATGGTTGCATTTATGTAAATCAATTTGAAACTTCATCCAGCAATCGCGAGTTGTTGGAACAGAagattaaaaatgcatttacgAAACGTCAAATAAGTCAACTGTATCAAGCAGTCGATAAGGACGGCAAAGAAATGGACATTTCAGATTCGGATAGCGATGAAGATGAAAAAAGCTATTTGTGCGAACTCTGCTATGAAACGTTTAAAAAACGAAAACTTCTGTTAAAACATCAAAGTGAACAACACAGGGATATTTTAATGCCTTTCACTTGCAAGGAATGTAAGATGCAGTATGTTAGTATTGATTTGTTACAACAACATATGAAAAGAGAATGTTGGAATGAACATCGACGAGTTGCTGAACAATGTGATTGTTGTAAAGTGCGTTTTATATGGCCGGATAACATGCTGAGACATAAAGAAATACAGcgatacataaataatgaaaattcgcaaaCGGAAAATGTGTGTCGTACCCAGGCACAGAAAACAATAATAGCTTCATCAATCTCCAATTCTGATGTGACAAGTGCCAATATCGAagtttgttattgttttttgtgtCCTAAAACTTTTGCCAATCATGATCAGTTCAATGATCATTTCATCCGCCATCGTCTCGCATCATCCACCATCAGAACTGTTGCTAGCACAATACATTCTGTATGTGGAAGGCAACATTCAGTGAAAAACTACTCGATTACTAATCAAATGGGTTTTGAGTTACATTTAGAGCTGGATTCGGAAACGGAAACTGAAAGCATCGAAAATGAAGAAAATGAACAGACATTACCATATAAATGTTGCATGTGTACGAAATTATTTAAGcgaaaatttcaaataactcAACATCAAACATCGATGCACAATTATGAATTGTTGGAACTCAAATGCGAACGTTGCTTTTTTAGAACTGTATCACAGAAAGTTTTAAATTATCATAAAGTAACCCAGTGTTTTAATGTTGAGAAAATGTACCAATGCGATCAGTgtaatttcaaatttatgtggCAAGAGAACCTCGAGAAGCATATTTCGATATTTCATACTTCTGACGTTTTCGTCAAAGCACTGCCTGCGGCTAACACAAGGAGCAATACTAATGCTCAATTCTTTGAATCAAAAGAAGCTTCAAAGAATGATTTGTTGTCAGTATTACATAAAAACGATTCTGATGCAATGGACGGCATTCAATCTAATGATAAATGTAAATGTCTCATTTGTGGAATTTACATTACGAAAACTAATTATTCATTACATATTATGAGACACAAATGTGACAAATCTTACAAATGCAATTTTTGCGAAATGGTCTTTATTACAAATTCGTCATTAAAGAAGCATCAGGACATGCATATAGAAGAACGTCCTTTCAAATGTACGTTATGCCGGAAATCATTCAAGCTTCAAAAAGGTCTAGATGTTCATAAACGTTTACACATCGGAAAACTACCATACAAATGCACAGTTTGCTCGAAATCATTTCTACTATTGGCACATCTGGCTAGTCATATGCGATGTCATTCTCGTAAAAAGCCGACTCCAGACAAGAAGTCGCACTCAACTGATTCTACCCAGCATGTACAAGGGGAGAGAAAGACGAACTTATGTCCTATTTGTGGTGTCAATTTGACATACAAATCAAATCTTACAATACATATTAGAAACCATACGGGCGAGAGGCCATTCAACTGCGATCTTTGTGATAAAAGATTTAACAGATTAACTATTTTAAATATGCATCGACGCACACACTTCACTGAACGTCCTTTCAAGTGTACAATTTGCGAGAAATCTTTTGTAAATAGAGCCAAATTAAAAGCACACATCCGCATTCACACTGGCGAGCGTCCATATCAGTGCACTGTTTGTCAAAAAAGATTTATGCATTCTACCTCTTTGAAGCGTCATTCACTTAATCATACTGGTAATAAACCTTTTATATGTGAGATTTGCAATCGACCCTTTAAGTGTCTCTCGTATCTCAAACAGCATCGTGTCAAAAGAGGCCATCATCCAGAAAATAGTTGA
Protein Sequence
MTNECFINGVQYKCRTCFDPGATVYPVAEECSNSITWRDLLTDIVKLKTNDDELLPKTICSKCLEKLISYYDFILHVQNVNEKYQQLLASGKHSPQNNSLASSSKNTAEFLAVSATTLPLGQCVPEIKFEDERLIPYDIVLNNNSRRKDAVKEDNCEPFMETLEEDVELALDMLQYQQRSQNQENRILEDDINDYNSDNSSTCADESEYLNGKREERKNKVNENGSSSSSSASEHHLPTSQPFEKKTEDQFCKYFPIEKFNKHLVCGVCKKLFSSPSAYRRHITMHQGKSYICAFCDHHAESKSYLIRHLKRKHPDESFKSNAKQIASMFGERLYSKPLELPRVECKLCCTTFVTKKKLLQHLESHSDVSTLDSLQLSSDIIQRWFPNKRNLQVIKTMICKDISEKNWIKYYTILNDFSYEISISDTDAEDLEEETEAPASKYKCELCGKDFLYKYQVFAHLREDHLNEKIPWKCSHCNLEFISIKMYELHKQTHCLSKHKLLHCPNCNGKFVWLVNMKKHNCVTKILDIEKPFNVKINETCNDEMRSSPETIIKCGLCDMTFEKLRDLRQHMPLHADGKTGVDFNGCIYVNQFETSSSNRELLEQKIKNAFTKRQISQLYQAVDKDGKEMDISDSDSDEDEKSYLCELCYETFKKRKLLLKHQSEQHRDILMPFTCKECKMQYVSIDLLQQHMKRECWNEHRRVAEQCDCCKVRFIWPDNMLRHKEIQRYINNENSQTENVCRTQAQKTIIASSISNSDVTSANIEVCYCFLCPKTFANHDQFNDHFIRHRLASSTIRTVASTIHSVCGRQHSVKNYSITNQMGFELHLELDSETETESIENEENEQTLPYKCCMCTKLFKRKFQITQHQTSMHNYELLELKCERCFFRTVSQKVLNYHKVTQCFNVEKMYQCDQCNFKFMWQENLEKHISIFHTSDVFVKALPAANTRSNTNAQFFESKEASKNDLLSVLHKNDSDAMDGIQSNDKCKCLICGIYITKTNYSLHIMRHKCDKSYKCNFCEMVFITNSSLKKHQDMHIEERPFKCTLCRKSFKLQKGLDVHKRLHIGKLPYKCTVCSKSFLLLAHLASHMRCHSRKKPTPDKKSHSTDSTQHVQGERKTNLCPICGVNLTYKSNLTIHIRNHTGERPFNCDLCDKRFNRLTILNMHRRTHFTERPFKCTICEKSFVNRAKLKAHIRIHTGERPYQCTVCQKRFMHSTSLKRHSLNHTGNKPFICEICNRPFKCLSYLKQHRVKRGHHPENS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-