Basic Information

Insect: Tachina fera
Gene Symbol: tio
Assembly: GCA_905220375.1
Location: LR999965.1:114031727-114044725[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.00024 0.027 16.3 0.6 1 22 350 371 350 374 0.92

2 4 0.0013 0.15 13.9 0.3 2 22 472 492 471 495 0.90

3 4 0.00014 0.016 17.0 1.3 2 23 576 599 575 604 0.92

4 4 0.00077 0.089 14.6 1.6 2 23 1117 1139 1116 1139 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.00024	0.027	16.3	0.6	1	22	350	371	350	374	0.92
2	4	0.0013	0.15	13.9	0.3	2	22	472	492	471	495	0.90
3	4	0.00014	0.016	17.0	1.3	2	23	576	599	575	604	0.92
4	4	0.00077	0.089	14.6	1.6	2	23	1117	1139	1116	1139	0.96

Sequence Information

Coding Sequence: ATGATGCTGCACGAGGCTGTGATGTTGGAAATCTATCGACAGGCTTTAAATGCCAGCGAACTTGCCAGTCCACGTTGCCAGTCACGCGAATCTAATGCTTCAGTATCAGCCGCTAACGATGTACGCTGTCCTTCAAATGAATCACATTATTCTGGCCATGAAGGTCATACACCCGGAGAAACACCTACAACAGCATCGCCACCAGTCGGTCTACCATTACCCGCCACCTTGGCACCAGCTGCAGCAGCCGCTCTCTTACCACCACAGTCAGCTGCAATGGCTGCATATTTCAATGCAGCTGCAGCAGCGGCAGCTCAACAGAATCATCTGCTATTAACAAATCCCTTAGCAGCAGCTGCCTCACTAGTACAACATGCAACACAACAAGCTGCACATTCCCCAAACTCACAGCAAACGTTGTCAACAAAGCCACCAAATAATACAAACAATTTAGCAGATACATCAGCCTTAGATTTTAGCACCAAAAGAAGCCGACGGCAGTCTGATGATGATGCCAATGCCAGTGAAGAGGATGAGGATGATGCTGATGGTGAAAAAATTAACGATAATGAGTCTGATAATGTGAATGATAATGAAGCAGATGATCTGAATAGTCCATTAGATTTATCAGTAAATAATGGACGCAAACGTCAATCAGACGAAGATGAACCAGTTATAATAACCAATCGGAAATTGGCAAGATCAAATGATTACAAATCATTGCCGCCATCAAGCACTTGGGTGCCACCAATAAATCCATATTTGGCTGCTGTAGCTGCTGCCAATCTGTCGCCAAAGACTCCGCTCTCATTGGATTggaatgccaaaacgaaaatagcaCCAAATGAGGCCACCAAAGCTTTAGAGAAAATGACTGAAATGACAAGACTAGGAGGATCAGCAAAAGCTGAACATAACGAAATATCAACTAGGCACTCAGCCATTTCTACAAATAATGCAGGCACTACAACGACAGCATCAAATGGCCGTCACAGTGCTTGGCAATCACATTGGCTGAATAAGGGTGCAGATGCTGTCAAAGATGTTTTTAAATGTGTCTGGTGTAAGCAAAGTTTTGCAACTTTAGCTTCGCTTACCACGCACATGAAAGAAACCCAACATTGTGGAGTTAATGTTCCTGCTAGTGTTGGCTCAAATTGTGCACCAACAAGTGGCACCGGCGGGAATCAAGTGACACAATCTTCTCATCATTCTCGTCATTCGACCACGCAAAGTAGTAGCACAGCAGCAGCTCAACAAGCAGCATTAGCTGGTAACAATGCAACAGCATCTGGTGGCAGTAAATCCGATCTAAACATGCTAATCAAAGAAACGATGCCTTTGCCACGCAAACTAGTGCGCGGACAAGATGTGTGGTTGGGCAAAGGGGCCGAACAAAcgcgccaaatattaaaatgtatgtGGTGTGGACAAAGTTTTCGTTCTCTAGCCGAAATGACAAGTCACATGCAAGAGACTCAACATTACACAAACATAATATCGCAAGAACAAATCATTTCTTGGAAGTCCACCGATGAAAAAACTTCACGAGATAGTAGTGGTGGTGGTAGCAGCGGCACTAATAGAACATCTTCAAATGCTGCTGccaatagcaacaacaacaacaacaacagcaataatgcCACAAACCTAACTATCAATAGCAGCTCTACATCTCCTACTAATAGTGCAGTGAATACAAACTCTACTGTTAGTGCTGTGCTGACATGCAAAGTGTGTGATCAAGCGTTTTCCACTTTGAAAGAACTAAGCAATCACATGATGAAAAATAACCATTATAAGGAACACATGATGAGAAGTGCGGCAGCAACTGAAAGTATGCCCACAATGATAAGGGGAAGAGGAAGGCAGGCACGGGAGAAGCGTAAAAAATCTTTGCCGGTACGCAAACTATTAGAAATGGAGAGAGCCCAGCAAGATTTCAAAGCAGCAGGTTTAGATCAGGCGCTTAAACCTTTAAGAGATTTTGCTGTTTCTACCAAATTATCTTGTGAAACTTGTGGCGAGAAGGTTGAAACTGCCATGTTTGTTGACCACATACGACAGTGCATTGATCGCAGCTTACTTATGTCACCTAGATctcaaaataataacaataatacccTTAAGTCTCCTTACGGTAATTTAACACCACAGGAATGCTTAAATAGTCCACAAACCCCTAATAGTCGTAGTGATGGTCGCAAAACTTCAGATGGCAATAGCTCTCCTTTGTCATCTTCCCATACTAGGGCGGACATTTTGTGTCCCCTGCCACCCACAGAATCTGAAAAGATTGCCGGCGGCACTTCGGTCTTAAATGCTTTGGAAcagttaatcgaaaaaagttttgaCTCAAGACAGCGCCACTCCTCTGGCTTTGGCGAAGCCACTTCAAGCAGCACTGCGCTGGGTTCGAGCATACTCAAACGTTTGGGCATAGATGATAATGTGGACTACACCAAACCTTTGATGGATCCTCAGACAATGCAATTTTTACGTTCCTATTCGCATTATCCCTCAAATCGTGACCGCAGTGCCAGTGAATCGAGTTCAATATCTGAACGTTGTAGCAGTCGCTTGGAATCGTTTACACCAGATCGTTGTCATGATCTTTCGCGACAACCGACACCCCGTCTCACTCCGGACAAAGCTTATGCCAATCTAAAAGAAACTAGAGACAACTTCTATGCAACTAAAATCAAAGCCGAGCCAATCGATTGCAGTGAACAACCAACCGATGCCGACAACATACCAATTAATGAAATACCAAAGAAAATTTCTGTCAAAAAAGAGTTTAATATACCAGAAGAACAAGAGGAATCAGAATTATTGCACAAAGTTAAAGAGAATGACATGAGACACATTCCACTAACACCAAATTCACGTGCCATAAGTCCCAGTATTAGCGAACGTTCCATAACGCCAAAATCAACATGTTCGTCAGGCGACAAGAAGTCCCATCATCTTAGCTTTACCGAAAGTAGCAGTCTTAATGCTTTATCATCTATGTTTAATAATCTTAACAACATGACTGCAACCAcaataagtaataataatagtcCCAATGTGGAAGCAAATAATAATGCTACCGCACCAGAGGCAAAGAAACCGAATGCTAATCCTTTGGCTGCTTTGCAAAAACTTTGCGAAACTACTGATGCACCTACAGCCAATACACGCAGCTCTTCtaccagcagcaacaacaatttgGCAATGCATTCAGCTTCGGCGGCTTCTTCGTCTACTTCTGGCTCTGCAACAAATGCGAGTGGCAGCAATACTGCCAGCATGTTAGCCTTTAGTTGGGCTTGCAATGATGCTGTTGTAACAGCAGATTCCATTATTAAATGTTCCTTCTGTGATACACCATTCAGCTCTAAGGGCGCTTATCGCCATCATTTGTCCAAGGTGCATTTTGTCAAGGATGAGCAGCAACATCAAATTGACTTCAACAATATGAAATCACCAGCTGCCGTTTCACCGAAATCCATGACTCCTCCCAAAAGCGTGACCCCAGCTAAGAGTCCTTCTATTCAGCAACGTTTAGAACCGACACCACCGTCCAGTGTTAATACTACACCAACAATCAATCCCTACGACGAGAGTCCGCaatctaaatttttaaaatataccgAGTTGGCCAAGCAGCTGTCGAGCAAAAATGCCTAA
Protein Sequence: MMLHEAVMLEIYRQALNASELASPRCQSRESNASVSAANDVRCPSNESHYSGHEGHTPGETPTTASPPVGLPLPATLAPAAAAALLPPQSAAMAAYFNAAAAAAAQQNHLLLTNPLAAAASLVQHATQQAAHSPNSQQTLSTKPPNNTNNLADTSALDFSTKRSRRQSDDDANASEEDEDDADGEKINDNESDNVNDNEADDLNSPLDLSVNNGRKRQSDEDEPVIITNRKLARSNDYKSLPPSSTWVPPINPYLAAVAAANLSPKTPLSLDWNAKTKIAPNEATKALEKMTEMTRLGGSAKAEHNEISTRHSAISTNNAGTTTTASNGRHSAWQSHWLNKGADAVKDVFKCVWCKQSFATLASLTTHMKETQHCGVNVPASVGSNCAPTSGTGGNQVTQSSHHSRHSTTQSSSTAAAQQAALAGNNATASGGSKSDLNMLIKETMPLPRKLVRGQDVWLGKGAEQTRQILKCMWCGQSFRSLAEMTSHMQETQHYTNIISQEQIISWKSTDEKTSRDSSGGGSSGTNRTSSNAAANSNNNNNNSNNATNLTINSSSTSPTNSAVNTNSTVSAVLTCKVCDQAFSTLKELSNHMMKNNHYKEHMMRSAAATESMPTMIRGRGRQAREKRKKSLPVRKLLEMERAQQDFKAAGLDQALKPLRDFAVSTKLSCETCGEKVETAMFVDHIRQCIDRSLLMSPRSQNNNNNTLKSPYGNLTPQECLNSPQTPNSRSDGRKTSDGNSSPLSSSHTRADILCPLPPTESEKIAGGTSVLNALEQLIEKSFDSRQRHSSGFGEATSSSTALGSSILKRLGIDDNVDYTKPLMDPQTMQFLRSYSHYPSNRDRSASESSSISERCSSRLESFTPDRCHDLSRQPTPRLTPDKAYANLKETRDNFYATKIKAEPIDCSEQPTDADNIPINEIPKKISVKKEFNIPEEQEESELLHKVKENDMRHIPLTPNSRAISPSISERSITPKSTCSSGDKKSHHLSFTESSSLNALSSMFNNLNNMTATTISNNNSPNVEANNNATAPEAKKPNANPLAALQKLCETTDAPTANTRSSSTSSNNNLAMHSASAASSSTSGSATNASGSNTASMLAFSWACNDAVVTADSIIKCSFCDTPFSSKGAYRHHLSKVHFVKDEQQHQIDFNNMKSPAAVSPKSMTPPKSVTPAKSPSIQQRLEPTPPSSVNTTPTINPYDESPQSKFLKYTELAKQLSSKNA*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00350584;
90% Identity: iTF_01399958;
80% Identity: -