Basic Information

Gene Symbol
-
Assembly
GCA_958431115.1
Location
OY288109.1:109210214-109212326[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.2 30 6.4 1.0 2 13 7 18 6 21 0.86
2 14 0.18 28 6.5 0.4 1 23 177 202 177 202 0.79
3 14 0.0014 0.21 13.2 2.1 1 23 208 230 208 230 0.98
4 14 4.9 7.4e+02 2.0 0.2 2 9 237 244 236 248 0.87
5 14 1.8 2.7e+02 3.4 0.5 2 13 266 277 266 289 0.80
6 14 1.3e-05 0.002 19.5 4.8 2 23 296 317 295 317 0.97
7 14 8.7e-05 0.013 16.9 0.6 1 23 323 345 323 345 0.97
8 14 0.23 34 6.2 0.5 2 19 352 369 351 374 0.82
9 14 0.0006 0.091 14.3 1.0 2 23 382 404 381 404 0.90
10 14 0.001 0.15 13.6 0.4 1 23 441 463 441 463 0.98
11 14 1e-05 0.0016 19.8 3.8 1 23 469 492 469 492 0.95
12 14 8.6e-06 0.0013 20.1 1.4 1 23 498 521 498 521 0.96
13 14 7.4e-05 0.011 17.2 2.4 1 23 527 549 527 549 0.98
14 14 5.2e-05 0.0078 17.7 1.4 1 23 555 577 555 577 0.98

Sequence Information

Coding Sequence
atgagTGTTGCAGAAAAAACTTGCAGGACATGTGGAAAAACATTTGAGGACAACAATGGATTTGGTCTTTGTTCACTATATAATTCCAGCGAATatgaaaacgaaattaaaatgGCTTTGGAAGAATTTGAAATATGGAgtttaaatATAACTCAAAATGATGGTCTACCGCAAAAAATTTGCCTAACATGTTTTGATAGCTTTTGTCAAATTCATAACTTCCGTTTGATGTGTATCGAAGCACAGATGAACTTTGGTGAAATGTGTACGGGTTTGGATATAATAATTAACGATGAAATGACTGACGAAGATGAAGATTTTCTAGAAAATTATAACGGTGAAAAATTAGTAATAGTTCAAGAGCATTACACATTTCCTGGTGATGAACTtgtgaaaacaacaacaacaactgaagaagAATTTACTGAATTCGGTTCAGATAATGTTGTCGAAGAACTTACAGCACTTGAACAGGATCTCGATAATAGAGAAAACAAACCTGAAGAATATAATCTCGATTTGAAACAATATCGATGTGAGTTCTGTATGGGATTTGTAAGTTTTGATGATCCTGATGAGCTTAATAGACACTATAACGAACTGCATTCCACGATTTTGCCATATCCGTGTCCCAAGTGTGATTTGCATTTCGACAAAAAAGGAAAGCGAAATAGTCATGTCCGTTCTCATTTTGATGTAAAACCACTTGAATGTGAACAGTGCGGCAAAAAGATTCGTGGTGATCAATTGATGATGGCGGAACATAAAGCATATAATCATGTAAACAGAAACCGTGAATGTCCAATATGTCagttaaagtttgaaaatatttccttaaaaaattattattatcatatgATTTGGCATAATGATTCCAAGCTGCTTAAATGTAAGTTTtgtgacaaaaaatttattcaaagccAACATTTACAAACACACGAAAGAACACATACTGGTGAGACGGATTATATATGCAAGGAATGTGGATTAGGTTGCAAAAACTCAATTCTCCTAAACAAACACATTCTTTTGCATGAGCGACAAGAATTAATAGAGTGCCCAAAATGCCCCAAAAgGTACTTTACTCGAATTGGTATTAAACTGCACGATAAGAAAACGCATAATCCAGATAAAAAACCTATCTATTGTGAAATTTGCAAGAAAACATTTCCCTATGCACATGATTTATTAGCTcacaattataaaaaacacGGTGGTCCGGCCCCTAAACGTACAAAACGAAGTGCTCGATCTACAACATCTGCATCTACTgcacttaaaattataaaaaaacataaaagaaggGATTTAATAAAGccatttaaatgtaataagtgtGAAGAAGCATTTGTGTTAGAAATACAATTATCGAGGCATTCAAAAGTTCATGAAGAATACAGGCCTCATCCATGCAAACTCTGTTCAAAGAGTTTCAAAAGAGAAGCGCACTTAAAATTGCACATGAACAATatccattttaataaaaaaccacaCAAGTGTTCAATATGCGGATCGGCATTTATACAGAAAAGTCATTTAAATGATCACATTGCTATCAAGCATaatgataTAAGAAATCACCAATGCAAAGTTTGCGAAAAAAGGTTTGGAACGTCTCAGGTACTGAAGATACATATGACTACACATTCAGACGAAAGACCATATATTTGCAAAATATGCCATAAAGGCTTCAAACAATTGATAGTTCTAAAATcTCACATGACCgttcatttttcgaaaaaaggagctaaatatttagaaaaagaagaaagagaaGAACATGAAATCAAAGAATAA
Protein Sequence
MSVAEKTCRTCGKTFEDNNGFGLCSLYNSSEYENEIKMALEEFEIWSLNITQNDGLPQKICLTCFDSFCQIHNFRLMCIEAQMNFGEMCTGLDIIINDEMTDEDEDFLENYNGEKLVIVQEHYTFPGDELVKTTTTTEEEFTEFGSDNVVEELTALEQDLDNRENKPEEYNLDLKQYRCEFCMGFVSFDDPDELNRHYNELHSTILPYPCPKCDLHFDKKGKRNSHVRSHFDVKPLECEQCGKKIRGDQLMMAEHKAYNHVNRNRECPICQLKFENISLKNYYYHMIWHNDSKLLKCKFCDKKFIQSQHLQTHERTHTGETDYICKECGLGCKNSILLNKHILLHERQELIECPKCPKRYFTRIGIKLHDKKTHNPDKKPIYCEICKKTFPYAHDLLAHNYKKHGGPAPKRTKRSARSTTSASTALKIIKKHKRRDLIKPFKCNKCEEAFVLEIQLSRHSKVHEEYRPHPCKLCSKSFKREAHLKLHMNNIHFNKKPHKCSICGSAFIQKSHLNDHIAIKHNDIRNHQCKVCEKRFGTSQVLKIHMTTHSDERPYICKICHKGFKQLIVLKSHMTVHFSKKGAKYLEKEEREEHEIKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-