Basic Information

Insect: Syritta pipiens
Gene Symbol: ZEB2
Assembly: GCA_905187475.1
Location: LR994572.1:80434196-80436307[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 3.6e-06 0.00038 20.9 4.7 2 23 235 256 234 257 0.95

2 11 8.4e-05 0.0089 16.6 0.2 1 21 320 340 320 341 0.95

3 11 2.6e-08 2.8e-06 27.6 0.5 1 23 349 371 349 371 0.99

4 11 0.0006 0.063 13.9 0.4 1 23 375 398 375 398 0.92

5 11 5.2e-07 5.5e-05 23.5 2.4 2 23 405 426 404 426 0.98

6 11 4.8e-07 5.1e-05 23.6 0.4 1 23 432 454 432 454 0.95

7 11 4.6e-07 4.8e-05 23.7 0.5 1 23 460 482 460 482 0.99

8 11 4.2e-07 4.4e-05 23.8 1.2 1 23 488 510 488 510 0.98

9 11 0.00083 0.087 13.4 1.0 3 23 518 538 516 538 0.98

10 11 0.00019 0.02 15.5 2.5 1 23 544 566 544 566 0.99

11 11 6.4e-06 0.00067 20.1 0.7 1 23 572 594 572 594 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	3.6e-06	0.00038	20.9	4.7	2	23	235	256	234	257	0.95
2	11	8.4e-05	0.0089	16.6	0.2	1	21	320	340	320	341	0.95
3	11	2.6e-08	2.8e-06	27.6	0.5	1	23	349	371	349	371	0.99
4	11	0.0006	0.063	13.9	0.4	1	23	375	398	375	398	0.92
5	11	5.2e-07	5.5e-05	23.5	2.4	2	23	405	426	404	426	0.98
6	11	4.8e-07	5.1e-05	23.6	0.4	1	23	432	454	432	454	0.95
7	11	4.6e-07	4.8e-05	23.7	0.5	1	23	460	482	460	482	0.99
8	11	4.2e-07	4.4e-05	23.8	1.2	1	23	488	510	488	510	0.98
9	11	0.00083	0.087	13.4	1.0	3	23	518	538	516	538	0.98
10	11	0.00019	0.02	15.5	2.5	1	23	544	566	544	566	0.99
11	11	6.4e-06	0.00067	20.1	0.7	1	23	572	594	572	594	0.99

Sequence Information

Coding Sequence: ATGTCGCTGGAAATAACAAAGATATGCCGGACATGCCTGGCACTGGAGGGAGCACTTTTATCCATTTACGATAGCAAAGGAACGTCTGGCAGTGGCGGATGCGTTGCAGACATGCTCGGGGATTTGACGAGTATTCCACCGAAACCATCGGATGGGATGCCTGAGAAAGTGTGCCTTACGTGTATCAGTGAGATCAATCGTTGCTATTCGTTCAAAATGAAGTGCGACAACTCGGATAGGACGCTGCGGCAGTTGTTGAATCTCACCGAGGATGAGGTGGAGGATACTCACGAAGAGATCAAGCTGAAGTCGGAAGAGGTGACGCCAGTGGAGTTGATCGAGGTGAAGAAGAAGCCGCAGAAGCGGAAAACGGAGATGAACTATCGAATCCTGAACGACGAAGTCGAAGCAATCACTGCGGGTCATTCGAATGAGATGTATGCCATGCAGGCGGAGGAGGACTTGGAGGCGTCGTATTTTGTGATCGCGTCGGAGGAGGATGAGCACCGGAGGACCGAGGACAAAAACGAGGAGGAGGACAACTCAGACGACTACGACGAACTGCTCCAGAAATACGTTCAGCAGCAGAATGAGAACGAGGAAGACGGCGACGGGGAGGAGGAGGACGAGGAGCAAGTCCAGGAGTCTGCGGAATACAAACCCACCAGCAGACGAGCAAAGCCGAGGAAAAAGGAGGAACTCAAGTGCCCCGTGTGTCCGATGACGTTCGTTCACCCGCGGAACCTCACCAAACACATGCACAGACACCACAACATGAGTGACGAGCCACAGACGAAGCAGGAAGAACAGAGAGAACCGGAGGAGCACGCAGAATCCCCACAGGACCACGATCCGGAGGAGAACTTCGAGATGGACATCCAGCCGCTCGAATCCGAGATGAATGTCATCGATGACACGGTCCACATGAAGGAGGTCTTCGTCGTGCAGATGAACAAGCATCGCTGCCCTCGATGCGGAGCCGGCTTCGCCCAGCAGAAGTCCCTGAACATCCACATCAAGCAGAACAAGTGCACGGAGAAGCAGTATTCGTGCGGGAAGTGTCAGAAGGTTTTCATCTCGCAGGAAAACCTCCGTGCACACATCCGCACCCACAAGGAGGAGTTCACGTGCAGCATCTGCGGGGACGTCTTCAGCCACGAGGAGGAACTCAACGAGCACAAGGCCGAGAAGCACAACCTCAAGATGAGGAATCAGTGTCCCCATTGCAAGAAAGTCTTTACCATGCTGTCGACCCTCAAGGACCACATGCGGATACACAGCGGCGAGAAACCATTCCTGTGCTCGGTTTGCGGCAAGGGCTTCAGCCAGAACGCGAACCTGAAGCAGCACGTGATGCGGCACAACAAAACGAAGCCGTTCAAGTGCGACGAGTGCCCGCGATCGTTCGTCAGCAAGGGCGAGCTGTTCTCGCACGTTCGCAGCCACACGGGCGACCACCCCTTCGTCTGCGACATCTGCAAGACGGGCTTCACGACCTCCAGTTCGCTGCAGAAGCACAAGCGCATCCACACCGGCGAGCGGCCGTACGGCTGCGACTTCTGCCCGATGCGGTTCACGGCGCTGAACACGCTGAAGAACCACCGGCGGACGCACACCGGCGAGAAGCCGTACAAGTGCCAGTACTGCCAGCGGGGCTTCGCGCAGAAGAGCGACTGTGCGATTCACGTGCGGACGCACACGGGCGAGCGGCGGTACGTGTGCCAGACCTGCGGCTCAGCATTCCAGCAGTCGGGCACGCTACGTACGCACATGAAGACCCACCGGCGGGAGAAGGACAACGAGCTGCAGTCGCAGGACGAGGGAGATGATGGTGATCAGGCGGCGGCAGCAGTGGCGGCGAATGTGGTCGACTTGCTTGACGAGGTGGACCTGCGGGAGCGCCCGAAGCACAAGACCGTCGACCTGGGCGAGGACGACCTCCTCCACTTGGCCATCGAGGAGTGCTCCAGCGAGAACAACGACTTCAGCGGTGAATGA
Protein Sequence: MSLEITKICRTCLALEGALLSIYDSKGTSGSGGCVADMLGDLTSIPPKPSDGMPEKVCLTCISEINRCYSFKMKCDNSDRTLRQLLNLTEDEVEDTHEEIKLKSEEVTPVELIEVKKKPQKRKTEMNYRILNDEVEAITAGHSNEMYAMQAEEDLEASYFVIASEEDEHRRTEDKNEEEDNSDDYDELLQKYVQQQNENEEDGDGEEEDEEQVQESAEYKPTSRRAKPRKKEELKCPVCPMTFVHPRNLTKHMHRHHNMSDEPQTKQEEQREPEEHAESPQDHDPEENFEMDIQPLESEMNVIDDTVHMKEVFVVQMNKHRCPRCGAGFAQQKSLNIHIKQNKCTEKQYSCGKCQKVFISQENLRAHIRTHKEEFTCSICGDVFSHEEELNEHKAEKHNLKMRNQCPHCKKVFTMLSTLKDHMRIHSGEKPFLCSVCGKGFSQNANLKQHVMRHNKTKPFKCDECPRSFVSKGELFSHVRSHTGDHPFVCDICKTGFTTSSSLQKHKRIHTGERPYGCDFCPMRFTALNTLKNHRRTHTGEKPYKCQYCQRGFAQKSDCAIHVRTHTGERRYVCQTCGSAFQQSGTLRTHMKTHRREKDNELQSQDEGDDGDQAAAAVAANVVDLLDEVDLRERPKHKTVDLGEDDLLHLAIEECSSENNDFSGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -