Basic Information

Insect: Synergus japonicus
Gene Symbol: topi
Assembly: GCA_900474275.1
Location: UCOH01005775.1:6228-8009[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.089 9.1 7.4 2.5 1 23 89 111 89 111 0.97

2 15 1.6 1.6e+02 3.4 2.9 1 23 116 139 116 139 0.83

3 15 0.029 2.9 8.9 0.2 2 21 146 165 145 166 0.92

4 15 3.8e-06 0.00039 21.1 1.7 1 23 173 195 173 195 0.97

5 15 4e-07 4.1e-05 24.2 1.9 1 23 201 223 201 223 0.96

6 15 0.00082 0.084 13.8 0.2 2 23 235 256 234 256 0.95

7 15 0.44 45 5.2 0.3 1 20 272 291 272 293 0.92

8 15 0.85 88 4.3 4.5 1 22 309 330 309 333 0.89

9 15 0.023 2.4 9.2 0.3 1 21 346 366 346 367 0.94

10 15 0.00012 0.012 16.4 0.1 1 23 372 394 372 394 0.95

11 15 3.3e-06 0.00034 21.3 2.3 1 23 400 422 400 422 0.98

12 15 3.4e-05 0.0035 18.1 0.3 1 23 428 451 428 451 0.97

13 15 0.035 3.7 8.6 1.5 1 23 457 479 457 479 0.89

14 15 2.5e-06 0.00026 21.7 3.6 1 23 485 507 485 507 0.99

15 15 1.9e-05 0.0019 18.9 3.1 1 23 513 536 513 536 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.089	9.1	7.4	2.5	1	23	89	111	89	111	0.97
2	15	1.6	1.6e+02	3.4	2.9	1	23	116	139	116	139	0.83
3	15	0.029	2.9	8.9	0.2	2	21	146	165	145	166	0.92
4	15	3.8e-06	0.00039	21.1	1.7	1	23	173	195	173	195	0.97
5	15	4e-07	4.1e-05	24.2	1.9	1	23	201	223	201	223	0.96
6	15	0.00082	0.084	13.8	0.2	2	23	235	256	234	256	0.95
7	15	0.44	45	5.2	0.3	1	20	272	291	272	293	0.92
8	15	0.85	88	4.3	4.5	1	22	309	330	309	333	0.89
9	15	0.023	2.4	9.2	0.3	1	21	346	366	346	367	0.94
10	15	0.00012	0.012	16.4	0.1	1	23	372	394	372	394	0.95
11	15	3.3e-06	0.00034	21.3	2.3	1	23	400	422	400	422	0.98
12	15	3.4e-05	0.0035	18.1	0.3	1	23	428	451	428	451	0.97
13	15	0.035	3.7	8.6	1.5	1	23	457	479	457	479	0.89
14	15	2.5e-06	0.00026	21.7	3.6	1	23	485	507	485	507	0.99
15	15	1.9e-05	0.0019	18.9	3.1	1	23	513	536	513	536	0.96

Sequence Information

Coding Sequence: ATGAGTGGTGATGAAGGTACAAAAATGAAAGTTCTTAATGAATCTTTAATTTGGTTTCAAGATGATCCAATTTCGTCAAACGAAATTTGTGAATTACCATCCAAATTCTTTAAGGAAACCTCTGGAAGTTCTTCTATATCTCTCCAGTGTCCAGGAAGcaccgaaaaaaattttaaatgtggaGCTTGTATGAATCTTTACCACACGAAGGAAATCCTTGAGACTCACAAGTGCAAACTTCCAATTGAAAATACTTCCAAGCCCTACGTTTGCACTCTCTGCGaagcaaaattcaatttcgaagAACATCTAAACTTCCACCTCAAATAccataatttaaaagctttctaCTGTGAAATCTGCAAAATAAGTTTTGGAAAAGAGcttcaattctttttccacTATAAAAGATATCATTCTAAAGAGAAGGTTGTATCCTGTCTTCAATGTGGAAAGCTTTTCCAGGAACAGGAAgaacttaaaattcatgtttgTGTTGATAGAAAAGCAAAGCCTCACGTCTGTGAGGTTTGCAATAAAAGATTTTCCGATGGCTACACTTTGAAGAGACATCTTATCACTCATCTTCCAGAAAAACCTTATAAATGCAATGAATGTTCGAAGAGCTTTACCCAAAAATCAAGATTGAATAAACATATCGCTGATCATGAAGTTGTGATGGAGAGTTCTCAGAATCTTTGGAAATGTATGGATTGTGGAAAAGTTTTTGGCACGTTAGAAGAAGCTgagaaacattttcagaatcatGATCAGAAGATTCTAATTGTTGAGGAAGTTTCGGCAACGAAGGTCTACCAGTGCGAATTTTGTAACAGTTATTTTGTGGAAAAGGAACTGATCAAAATTCATCGAACTGTCATGGATTGGAAGCAACATCAGAAAGCTTTTAAGgtTCAGGTCCTCTTCATCTGCGAAATCTGCAACACGGAAGTGAAACACCTTCACGTCCTCTACAGGCACTACCACAAAAGACTTCACTATCTCCCTCGATCAATGGAATACGGAACTGGAAAATTCGCCTGTGAACGCTGTGGATCAGTTTTTCAAGATCTCAACGAATTCAAAAATCACAAGAGGGACCGTTGTTCAAAATTCCTCTGCGACATCTGTGGAAATTCTTTACCTTCTGCAAGTTCCTTAAATGCTCACAAAAGACGTCACAGTGGACTCAAGCCCTACGTTTGTAATATTTGTGGAAAAAGTTACACGCAGTCGGGTCATATGTGGACTCacaaaagatttcatatgGGGATCAAACCTTATGCTTGTGAATACTGCGATCAAAAATTCACAATCAAACCCGATCTAGCTGATCATATAAGGAAAAAACACACGAGGGAAAGGCCTTTTAAATGCCAAGTTTGCAATAAAACTTTTCTCACTGGATCAGTTTTTTATCAGCATAGACTTATTCACACAGGCAATAGAAGATATAAATGTTGTTATTGTCAAAAAGCTTTCACGAGGACTGAGGCGTTGAAAAATCATATTAAGATTCATACGGGAGAAAAACCTCATGCTTGTGATGTTTgcggaaaatattttagacaGAAAGGAGATATGAAGAAACATAAGAAAACTCAGCATACTGAAAAAGTTGTAGAATTATAG
Protein Sequence: MSGDEGTKMKVLNESLIWFQDDPISSNEICELPSKFFKETSGSSSISLQCPGSTEKNFKCGACMNLYHTKEILETHKCKLPIENTSKPYVCTLCEAKFNFEEHLNFHLKYHNLKAFYCEICKISFGKELQFFFHYKRYHSKEKVVSCLQCGKLFQEQEELKIHVCVDRKAKPHVCEVCNKRFSDGYTLKRHLITHLPEKPYKCNECSKSFTQKSRLNKHIADHEVVMESSQNLWKCMDCGKVFGTLEEAEKHFQNHDQKILIVEEVSATKVYQCEFCNSYFVEKELIKIHRTVMDWKQHQKAFKVQVLFICEICNTEVKHLHVLYRHYHKRLHYLPRSMEYGTGKFACERCGSVFQDLNEFKNHKRDRCSKFLCDICGNSLPSASSLNAHKRRHSGLKPYVCNICGKSYTQSGHMWTHKRFHMGIKPYACEYCDQKFTIKPDLADHIRKKHTRERPFKCQVCNKTFLTGSVFYQHRLIHTGNRRYKCCYCQKAFTRTEALKNHIKIHTGEKPHACDVCGKYFRQKGDMKKHKKTQHTEKVVEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01390549;
90% Identity: -
80% Identity: -