Stip008745.2
Basic Information
- Insect
- Synanthedon tipuliformis
- Gene Symbol
- Zbtb8b
- Assembly
- GCA_947623395.1
- Location
- OX392437.1:370833-381143[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00025 0.014 16.0 2.0 1 23 278 300 278 300 0.98 2 12 1.3 75 4.4 0.8 1 23 307 329 307 329 0.94 3 12 0.055 3.2 8.7 0.2 1 23 333 356 333 356 0.98 4 12 0.096 5.6 7.9 7.1 1 23 363 385 363 386 0.96 5 12 1.4e-06 8.4e-05 23.1 0.3 2 23 392 413 392 413 0.98 6 12 8.7e-07 5.1e-05 23.8 4.7 1 23 419 441 419 441 0.98 7 12 0.0001 0.0059 17.3 2.9 1 22 447 468 447 472 0.94 8 12 0.0007 0.041 14.6 0.1 1 23 480 503 480 503 0.93 9 12 0.0019 0.11 13.3 0.0 1 23 509 532 509 532 0.94 10 12 0.095 5.5 7.9 0.7 1 21 541 567 541 570 0.52 11 12 4.1e-06 0.00024 21.7 1.0 1 23 579 601 579 601 0.98 12 12 3.2e-05 0.0018 18.9 0.5 1 23 607 630 607 630 0.96
Sequence Information
- Coding Sequence
- ATGGAAGACAATAGCTTATTGCAAGACATTGTTTTTAAACGTGAAGTCGAGCCGTGTACACAAATATGTCGCTGTTGTTTATCCACAGATAAACAAATGAAAAATGTATTGGATTTCCGAAACTGTTTCGAAGAATTAGCGGGGATAACGGTATCTGAATCTGATGGTCTACCTCAATGGTTGTGTGAAGAGTGTTGTGCCCTCATCACAAAGGCGGCCAGGATCCGATGGAAAATACTAAAGGCTCATGGTTTATTGTACGAGTATTCCTCTAGATGTGCACCGTTTCCAATCGACGCTCAGGACGTAGAACTCACTAGATATGCATCACCGAATCTCCATAGGACTCCGACTCTCATCCTAGATTTTACAGTTAGCATAATGGGCTTCAGTAAGGCTGTGCAGCACGAGAAGAGAAATGAAGGTGAATTTTTAGAATTAGATTTGCCATCAACGGAGGAGCCCCAAGAGGCCGTGAAGGAGGAAGGTGGCTTTTCGGATTACGAAGACAACATCACTCTGGAGGAGTACAGATCGACAGTAAACAAAAGTCCTCAGCGCGATTCCGCAGAATCCTTCGATCGTGCGGAGATAGAGAAAGACACCGTCGAAGTGAGTGGCAACAAGAAGAGGAAAGTTAAGAAGAGTGAAAAGAAGCCTCGAAAGAAAAAGAAGAATGGCGAGGAAGATGCAAGCGAAGAAACGCCAACCAAGTCGTACATAAGAAAAACCATCGAAATCGATCCAGCCAAGATACGGATAGTGACACTGAATCCCGAAGAGCAAATAAAACAGAGAGAGGAGGAGAGCAAGGCTGGCCTGAAGTTTCCCTATCAGTGCAACTTGTGCTACAAGGGCTTCAATTTTGAGGCCAAATTACAAAATCACATGTACAAACACAGTCCGGCGCGCGGCACGTATAAGTGCAAATTGTGCACAATGTACCTGCCCACAATGTACAGTTACTCGGTGCATTCGCTCATTCACACGCGAAGGTACGAGTGCGTCCAGTGCGGCAGACGGATGATAGACAGACAGAGCATCATCGATCATTACAGAACGGAGCACGAGGGTCTTCTGTCTGTGTACACTTGTCACCTGTGCGGCAAAGTATCCAACAATAACAAGACGCACAGAGGTCACATGCGAAACCACCATTCGGGCGAGAGGCCCAAGTGCGATCAGTGCGGAAAGACTTTCGTCAACAATGACTCGTTGGCGCAACATTTGCAAATTCACGAAGGCATAAAGAACTACGAGTGCCCCGAGTGCAATAAAAAGTTTAGAACTCGCACTCAACTGAAACATCATCAGCTCAAACACACCGATGTCAAAGATTACTATTGCGTTGAGTGCGATGTTAGATTTAAATCTCAACATAATCTGCGTCAGCATCTAAAGAAGAATTTAAAACACAAGGATAAGCAGAGCTTCAAGTACCTGTGCACGCGGTGCCCGAAGCGGTTCGAGAACTCTGCGGCGCTGTCGGCTCACGTGGCGGTGCAGCACGAGGGAGTGCGCGCGCACGCGTGCCCGCAATGCCCGGCGGCGCTCGCCACTCGGTCGTCACTGGCGAAGCACGTGCGCGCGGTGCACAAGGGCGCGAGGGCGCCGCCGAGGCACGTGTGCGACACGTGCGGCAAGGCGTTCCGGTGCCCGGCGGCGCTCGCCACTCGCTCGTCGCTGGCGAAGCACGTACGCGCGGTGCACAAGGGCGCGAGGGCGCCGCCGAGGCACGTGTGCGACACGTGTGGCAAGGCGTTCCGGGGCAAGAGCGTCCTGACGAACCACGTGCGGACCCACACGGGCGAGAAGCCGTACGAGTGTTGGGAGTGCGGCAGGAAGTTCACTCAGCGGACCGCCATGAGGACCCACGTCAAGTTGGTCCACTTGAAGATCAGGAGAACTGCCAAGATAAAGCCAGAAATGGCCGCGGAAGAGCCTAAAATGGAATCAATTTTCAAAGAAGAAGCTCCGCTCGTGTACGAGGGTTGGAACAAGAATCAGTTGCAACCGTGCGATATATATTTCACTGTGGCGACAGCCCTGGCACCTTAA
- Protein Sequence
- MEDNSLLQDIVFKREVEPCTQICRCCLSTDKQMKNVLDFRNCFEELAGITVSESDGLPQWLCEECCALITKAARIRWKILKAHGLLYEYSSRCAPFPIDAQDVELTRYASPNLHRTPTLILDFTVSIMGFSKAVQHEKRNEGEFLELDLPSTEEPQEAVKEEGGFSDYEDNITLEEYRSTVNKSPQRDSAESFDRAEIEKDTVEVSGNKKRKVKKSEKKPRKKKKNGEEDASEETPTKSYIRKTIEIDPAKIRIVTLNPEEQIKQREEESKAGLKFPYQCNLCYKGFNFEAKLQNHMYKHSPARGTYKCKLCTMYLPTMYSYSVHSLIHTRRYECVQCGRRMIDRQSIIDHYRTEHEGLLSVYTCHLCGKVSNNNKTHRGHMRNHHSGERPKCDQCGKTFVNNDSLAQHLQIHEGIKNYECPECNKKFRTRTQLKHHQLKHTDVKDYYCVECDVRFKSQHNLRQHLKKNLKHKDKQSFKYLCTRCPKRFENSAALSAHVAVQHEGVRAHACPQCPAALATRSSLAKHVRAVHKGARAPPRHVCDTCGKAFRCPAALATRSSLAKHVRAVHKGARAPPRHVCDTCGKAFRGKSVLTNHVRTHTGEKPYECWECGRKFTQRTAMRTHVKLVHLKIRRTAKIKPEMAAEEPKMESIFKEEAPLVYEGWNKNQLQPCDIYFTVATALAP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01386978;
- 90% Identity
- -
- 80% Identity
- -