Basic Information

Insect: Synanthedon andrenaeformis
Gene Symbol: IKZF1
Assembly: GCA_936447275.2
Location: CAKZFQ020001375.1:74807-81309[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.67 42 5.3 0.7 1 23 52 75 52 75 0.97

2 18 0.00028 0.017 15.9 0.5 1 23 82 105 82 105 0.98

3 18 0.44 28 5.8 4.3 1 23 182 204 182 204 0.97

4 18 9.5e-05 0.0059 17.4 0.6 2 23 210 231 209 231 0.97

5 18 0.18 11 7.1 4.9 2 22 496 516 495 516 0.95

6 18 6.4 4e+02 2.2 1.5 1 23 612 634 612 634 0.80

7 18 0.58 36 5.4 0.3 2 23 754 775 753 775 0.96

8 18 0.064 4 8.5 0.6 3 23 852 872 851 872 0.96

9 18 0.1 6.4 7.8 0.7 1 23 880 902 880 902 0.95

10 18 0.051 3.2 8.8 3.9 1 23 933 955 933 955 0.95

11 18 6.8e-05 0.0043 17.8 4.2 1 23 963 985 963 985 0.99

12 18 2.2 1.4e+02 3.6 0.6 1 23 1069 1091 1069 1091 0.94

13 18 1.3 83 4.3 4.7 1 20 1147 1166 1147 1169 0.90

14 18 0.072 4.5 8.3 0.2 1 23 1175 1197 1175 1197 0.95

15 18 0.14 8.8 7.4 0.4 1 23 1264 1286 1264 1286 0.93

16 18 0.017 1.1 10.3 1.6 1 23 1292 1314 1292 1314 0.95

17 18 0.0066 0.41 11.6 2.6 1 23 1404 1426 1404 1426 0.97

18 18 0.0029 0.18 12.7 3.2 1 23 1432 1454 1432 1454 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.67	42	5.3	0.7	1	23	52	75	52	75	0.97
2	18	0.00028	0.017	15.9	0.5	1	23	82	105	82	105	0.98
3	18	0.44	28	5.8	4.3	1	23	182	204	182	204	0.97
4	18	9.5e-05	0.0059	17.4	0.6	2	23	210	231	209	231	0.97
5	18	0.18	11	7.1	4.9	2	22	496	516	495	516	0.95
6	18	6.4	4e+02	2.2	1.5	1	23	612	634	612	634	0.80
7	18	0.58	36	5.4	0.3	2	23	754	775	753	775	0.96
8	18	0.064	4	8.5	0.6	3	23	852	872	851	872	0.96
9	18	0.1	6.4	7.8	0.7	1	23	880	902	880	902	0.95
10	18	0.051	3.2	8.8	3.9	1	23	933	955	933	955	0.95
11	18	6.8e-05	0.0043	17.8	4.2	1	23	963	985	963	985	0.99
12	18	2.2	1.4e+02	3.6	0.6	1	23	1069	1091	1069	1091	0.94
13	18	1.3	83	4.3	4.7	1	20	1147	1166	1147	1169	0.90
14	18	0.072	4.5	8.3	0.2	1	23	1175	1197	1175	1197	0.95
15	18	0.14	8.8	7.4	0.4	1	23	1264	1286	1264	1286	0.93
16	18	0.017	1.1	10.3	1.6	1	23	1292	1314	1292	1314	0.95
17	18	0.0066	0.41	11.6	2.6	1	23	1404	1426	1404	1426	0.97
18	18	0.0029	0.18	12.7	3.2	1	23	1432	1454	1432	1454	0.98

Sequence Information

Coding Sequence: ATGCTACAGCCGATGTCGTCGATCTCACACCTCGCCGAAGCCAATACTCGTACGCGCTCCTGCGAAGGTCGCGTGAGTGGCGACGTGCATTCGGAGACTTCTTCGGATGCCACAGAGGAAACTGAGTTGCCAGATTGCAAGATAAAAAGGAACTACACATGCATGAAATGCTCTTTTTACACGCAGAACCCCCGCGCTTATCTGATTCACATGCGCGAGGTGCACTTTGTGAAAATGAAGATTTACGAGTGCCCCCAGTGCACTTACGCATCGAAGCAACTGCAGAAACTTATACGTCATATGAAAATGGTCCATGGGAAGTCTTCTTTGGTCCAAGCTAATAAAACGGAAGTTGATACGAATAACGAAAGCGAAAACGCTACAGAAAATGCAGAGCGTATAGAAGATTTACTTGAGGAAATAGAGGAGTGTGATGATTCAGAGGTGAAAGATTATGAGGAGGAATCGATGGAAGCAATTGACGATGTCGACGGTGCGGGTGTGCAGATAGGAAAAACTATGTCCGAGAAAACGTTGAAGTTTTTCGCGTGCGACAAATGCACTTATGTGACCCATAAACGTGGAAGATTCACAAAACACATTAGATATCACTCTATGCCGATGATAAAATGTACTATATGCGATTTCCGTTCACCTTACAAGTGGAATCTAGAAAGACACATGAGGAATCACGAGGGGAGTGGAAAATTCTCTTGTTTCGCGTGTAATTTCACATCCGATATCAAGCAGAGTCTGACTGTGCATGAACTAAATCACCACACTCCGCCAACGAACCAAGCCAACATGAGTTTGAGTCGTCGCCGCACCCGAGTGGGTGCCAGCGATGTTGTATTTAGTGAGGAAACTGTGAAGGAGGATAAGGGCAGCGGCGGCTCGGTTTCTTCTAATGAGGCCTCGGATATGGGTGTACAACATGCAGACATAGAGATGGTAGACTATAGCAGTGATTCGAACGACGCCACAACATCCGATGTAGTTGCCAAGAAGGACCAGCCGCAGTTGGCACAAGATACACAAAGTCAACTATCGCCAAACAGCATAACAGATGAAGCAAAAGGGGACATTTATAAACAAAATAGGAAAATGTCCAGACCAATACCACAGTTGATACCGTTAAATTCGTCAACACCAAGCCAAAAGTCGTCGCCAGGCGAACCGCCCATGAAGAAATTTAAAGAAAATTCTAATAACAATTCCGATATTGATTGTCAGGAAAGCAATTTATCATCAGATATTTGTTCTAATGGAAGCAATATTACAAACGAGATCGGAAGTCGTAAGAAAAATGAATCTTTCTTTGACAAATTAAAAGAAAGACTTTTAACTGAAACAGGGGAAGAAGGCGCATTGGTATGTAAAAACTGTGGTCTCGAGAGTAAGTGTTTGTCCAAGCATTCGGTACACGAAAAAAGTTGCATGGCCCTATCAAATCGTAGTTCTAATTCATTACTTTCAAGCTCCACTCGTTGCCAACACTGCAGACACCGATGCAAGTCTAGTGCCGATCTCTACATACATATGCAAACTTGCAGAAAAAAGGACCATAAAGTTGATAGTGACAAATTATCAGAGGTAAAAAATGACAACAACGGTGAAATGGCCGCCCCCAATCCAGAACCGCATCCAATGGAGAATGTTGTTTTCGTCTGGAACAATATTAACCAAGACACAAATAAGTTTGACCTCCCACTCGACATACATATAAATGATGACTCCACACTCCCTGAACCGAACAGAAGTTTCGATATTGAACCTGCTGATGAAAACGAAAGTATGAACTTGTCACCGAGCCAAGCTGGTGGTAAAAAAGTTTTCAAGTGTCCTCACTGTCAGTTTTGGGCTTCTACTGCATCTAGATTTCACGTGCATATCGTAGGACATCTGAATAAGAAACCGTTTGAGTGCTCTTTGTGCAAATATAAGTCGAATTGGCGATGGGACATAACGAAACACATTAAGCTGAAATCGGCTAGAGACAAGGAACACAACAACGCTAAGGTTTTAATGACTGATGAAACAGGCCGCAGAAACTACAGTAAATACTATAAGTTCCTAGCTGTGCCAGTATTGAGCGAAAGTGGACAAACCAAACTTCAATATGTCCACCAAAGTACTTTAATCGATCCTTCTCTAGAAGCCGACGGGGATGAAGGCTCTAGCCGCGAAATGCAACCCCTTAATCTACAAACTCATTCAGAAAATTTTAACAATTCTAACAAACCTAAGAAAACTTTATGGAAATGTAAAAAATGTAATTATAAAGATCCATCTAAAGAGGCATTATTAGAACACGTTCGAGAACATTCTAGACCAGAAGAAAGCGATGATATGAAAAATAAGAAGATAGATGGCATTGATATTGCAGACTTGGCTTATCGATGTGGACATTGCCACCAACTATCCAACTGGAAACATGTTATACAGAGACACTGTCGGCTAAAACATGGAGGAATAGTAAAAGTGATAACAACAACGAGACCAAAATTCGACCCAAACTCAATTCACGCACAAAACGACATGAACGGAGAAAATTGTCTAAAGTGTCCATTTAAAACGGATGACAAGAAAATGCTCGCCGCACACATGCAACAACACGAACCGTCCATGCAGTCAATATTCAAATGCTTCTTCTGTCCATATTTTGTAAAGAGTATTGAGGATTTAACGCAACATCTTGTTCTACACGGCATCACCGATCCCGAGGAGTACATCGGAAAAAGTGTAGCGGGAGATGACTCTCTTTTAACAGACCCCAACACGTCATTCAGCAAACGCCACAAATGTAATGAGTGTCCATATGAAACTAACAGCAAATCTCAGTTTACCTACCACGAACAGTTTCATCGGCTTCCAGCTGACACTCCATATAAATGTCCAGAATGCAATTATAGTGTATCTAAGAGACATCTTCTTCACCAGCACATGCGAGTTCATGGTATTTCACCGAAGAAAAGTGAGTTCGAACAAGAATTTGATACTGTATCGTCAACGTCAACAAAACAGGAAATGAAAGACTTGTTTCAATTTCTTGACGAAATTCCTTGCTTCTGGGTATCGGCTAGAAACGAATTCCACAAAATGTATAAATGTCGCTACTGCTCTTATGTAAATGCGCAAAGATGTAAGATACCAAATCATGAAAAAATTCATTGTGTTGTCTTCGGTAAAAGCAAAATGGTACTGTATAAATGTCTGGAATGCAAATTTACCTCCGACTATCCAAACAGGTTGGCTGAACATTCAAAAGCTCATGGACAAATATACGGTAGAATATATTGTCGTGTTGACCCAGAAGTACCTGATGAGGAACAAATTGCAAAATTGAGAGAAGTGATAGAACACGAAAAGCTAAATGCCACAGACGATTGTGTTAAAGAAGAAGGTTCTACAAATGACAACGAAGAGTTTAAGACGTTATATTTTTGTCGAAAATGTCCCGCAAGATATTTTAACAGCAGTGAACTTAAGGTTCATTGCAAATTCCACGAGTTAAGTTTTATTCATAAATGTAAGTATTGTGAGTATTCTGTTCCTGGAGAGGAAGAGTTGATGGCACACGAATTTGTTCACTCGGAAGAATACCATACTAAATCCAATGTGCTTAATTACATGCACAAGGCTCACCCTGCTTTTGAGCAACCGACCGTTGAAACTTTGCAAAGTTCAAATGATTCGGAAACTATATGGGTAGTTTCCAACCGTGGTAAAAACTGTGGCGGTGCAGATACACACAAAAGAAGTAACGAAAACAAACATGTACCAAAACAATATTACTGCAAAGAATGCCCAGCTAAATTTCTGAAAAATTCTGCACTAACTTATCACGTCGGTTTGCACGGTGGGGAAGGTGATCATAGGTGCAGAAAATGTAACTACACTGTAAAGAACGTTGGCAATCTAGCTAAACATGAATTGTTGCATGAAAATGAAGGCAAAACTCCCGGTTGTGATTATGAATCGGGGGATGACGGTGACTACAAAAATGTTCCTTTATCTGGTACAGACCTATTCCAAAGAAAAACAGAAGCTCAAAAGAGAGTGTTGACCGATAAGGATAAGCTGGTTAAACCAAATGATCATTTCCCACCTGTTCTTCAGGCGGATCCACAGTTTGGTTATTTGATACATGGTAATCCTGAATTCATATACCCAACATATCTCAAAAACGGGCGTCAAAAAGAAAAAAGATACAAATGCCACAAATGCCCCTCGGCGTTTGAAAAAAGAGAGCAATACAAGATACATTTATCACTACATGGTTCAAAACAAAGATACCACTGTCAACTATGTGATTACTCTGTAAAATATTATGCCAATTATGTCCAGCATATGAGAAAACATCAAATGAATGATGAGGCACAGGCTGAAAGAAAAAAAGAAAACAATGAGTACTCAG
Protein Sequence: MLQPMSSISHLAEANTRTRSCEGRVSGDVHSETSSDATEETELPDCKIKRNYTCMKCSFYTQNPRAYLIHMREVHFVKMKIYECPQCTYASKQLQKLIRHMKMVHGKSSLVQANKTEVDTNNESENATENAERIEDLLEEIEECDDSEVKDYEEESMEAIDDVDGAGVQIGKTMSEKTLKFFACDKCTYVTHKRGRFTKHIRYHSMPMIKCTICDFRSPYKWNLERHMRNHEGSGKFSCFACNFTSDIKQSLTVHELNHHTPPTNQANMSLSRRRTRVGASDVVFSEETVKEDKGSGGSVSSNEASDMGVQHADIEMVDYSSDSNDATTSDVVAKKDQPQLAQDTQSQLSPNSITDEAKGDIYKQNRKMSRPIPQLIPLNSSTPSQKSSPGEPPMKKFKENSNNNSDIDCQESNLSSDICSNGSNITNEIGSRKKNESFFDKLKERLLTETGEEGALVCKNCGLESKCLSKHSVHEKSCMALSNRSSNSLLSSSTRCQHCRHRCKSSADLYIHMQTCRKKDHKVDSDKLSEVKNDNNGEMAAPNPEPHPMENVVFVWNNINQDTNKFDLPLDIHINDDSTLPEPNRSFDIEPADENESMNLSPSQAGGKKVFKCPHCQFWASTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDKEHNNAKVLMTDETGRRNYSKYYKFLAVPVLSESGQTKLQYVHQSTLIDPSLEADGDEGSSREMQPLNLQTHSENFNNSNKPKKTLWKCKKCNYKDPSKEALLEHVREHSRPEESDDMKNKKIDGIDIADLAYRCGHCHQLSNWKHVIQRHCRLKHGGIVKVITTTRPKFDPNSIHAQNDMNGENCLKCPFKTDDKKMLAAHMQQHEPSMQSIFKCFFCPYFVKSIEDLTQHLVLHGITDPEEYIGKSVAGDDSLLTDPNTSFSKRHKCNECPYETNSKSQFTYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHMRVHGISPKKSEFEQEFDTVSSTSTKQEMKDLFQFLDEIPCFWVSARNEFHKMYKCRYCSYVNAQRCKIPNHEKIHCVVFGKSKMVLYKCLECKFTSDYPNRLAEHSKAHGQIYGRIYCRVDPEVPDEEQIAKLREVIEHEKLNATDDCVKEEGSTNDNEEFKTLYFCRKCPARYFNSSELKVHCKFHELSFIHKCKYCEYSVPGEEELMAHEFVHSEEYHTKSNVLNYMHKAHPAFEQPTVETLQSSNDSETIWVVSNRGKNCGGADTHKRSNENKHVPKQYYCKECPAKFLKNSALTYHVGLHGGEGDHRCRKCNYTVKNVGNLAKHELLHENEGKTPGCDYESGDDGDYKNVPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGYLIHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYHCQLCDYSVKYYANYVQHMRKHQMNDEAQAERKKENNEYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01388050;
90% Identity: iTF_01387216;
80% Identity: -