Basic Information

Gene Symbol
-
Assembly
GCA_936447275.2
Location
CAKZFQ020000511.1:24909-45321[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0021 0.13 13.1 1.0 7 23 551 567 545 567 0.88
2 14 0.04 2.5 9.1 0.1 1 23 570 592 570 592 0.98
3 14 0.00024 0.015 16.1 3.4 1 19 598 616 598 621 0.89
4 14 0.00021 0.013 16.3 2.8 1 23 627 649 627 649 0.94
5 14 7e-07 4.4e-05 24.1 1.6 2 23 656 677 656 677 0.98
6 14 8.2e-05 0.0051 17.6 0.8 1 23 683 706 683 706 0.92
7 14 6.9e-05 0.0043 17.8 2.8 1 23 712 735 712 735 0.94
8 14 0.00017 0.01 16.6 2.0 2 23 741 763 738 763 0.89
9 14 3.1e-06 0.0002 22.0 0.8 2 23 772 794 771 794 0.93
10 14 5.7e-07 3.6e-05 24.4 0.7 1 23 799 822 799 822 0.95
11 14 3.1e-05 0.0019 18.9 0.6 2 23 828 850 827 850 0.96
12 14 0.00092 0.057 14.3 1.5 2 23 856 878 853 878 0.87
13 14 4.3e-06 0.00027 21.6 0.3 2 23 887 909 886 909 0.93
14 14 4.7e-05 0.0029 18.3 0.4 2 23 918 940 917 940 0.95

Sequence Information

Coding Sequence
atggatgctgcgagacaacgaggacttgaggagccggaggaaggcaccgatgctgaattgcttcctacggcagcaccttcatcgagcccgtcgatggacctcgctgcgctgctagctgctgtacagagcatacaagccagccaggaagCTGCTCGCCGTGAACAGGAAGCCGCTGTACAAAGGATACAAGCCATTCAGGAAGCCGCTCGCCGTGAACAGGAAGCCGCTGTACAGAACATACAAGCCAGTCAGGAAGCCGCTCGCCGTGAACAGGAATCAACTAGCCAAATGTTGCTTTCAAAATTGGACACAAGCCTTGAAGCGATCTGTGACAAGGTTAAACAGGTTGAGTCCGAAGTAAAAGGGGTCTCACTGAAATTCGAAGGCCTAGAAGAGAGACTCGACCAAACCGACAGTCGCCACCAAGCGCTCGCCGAGAAAGTGCAGAAGCTGATGACGAGAGAGGCAGTCCTCACTGCGCCGGTACCTACACAAGGCagattggacttgccacgGGATCCGGGTTTGATTTCAGGCAAAGTTGGCTCTCGTCTGGATTTGGACAGTAGCTCTATATGTATATCTGGATCTGGCGGCAATAACCACCCCTTACAGAAAACCTTCGTGAAGGAACAGCATGTGTGCTGTTGTGTTTCGTTTGTACCCTTCAAAGATAAAAATATATATACAATATGCGACAAGTGTATTGAAAAACTACGTATCTCAATGGAATTCAAGAATTGTGTCCTCGCCTGTAAAAACAATGCTTGCTGGCGGGGGCACTGCAGTGCTCGACTTGACGGGGGCACTGCAGTGACCCCAGATATAAATCAAAATACCTCCAAAGATAAAGACAGTGACACGGATATAATAAATAAGGTTTTAGACAAAGAGTCAACTGAAGAGGTCAAAGTGGAAGAAACCTTCAGCGAATCTGAAGAATTTACAGCCAACATCGAAGTTAAAATGGAAGAGGTGGTCGATGATGAAGACTCGAGTACAAATAAAGTGTTAGACAGAGAGTCCAACACAGATGTCACAATTGAAGAGAGCAGAAAAGAAGCAGACGAAACGTTGAGTGAATCTGAAAATACCTCCAAAGATAAAGACAGTGACATGGATATAATAAATAAGGTTTTAGACAAAGAATCAACCGAAGAGGTCAAAGTGGAAGAAACCTTCAGCGAATCTGAAGAATTTACAGCCAACATCGAAGTTAAAATGGAAGAGATGGTTGATGATGAAGACTCGAGTACAAATAAAGTGTTAGACAAAGAGTCCAACACAGATGTCACAATTGAAGAGAGCAGAAAAGAAGCAGACGAAACGTTGAGTGAATGTGAAAATACCTCCAAAGATAAAGACAGTGACATGGATATAATAAATAAGGTTTTAGACAAAGAGTCAACCGAAGAGGTCAAAGTGGAAGAAACCTTCAGCGAATCTGAAGAATTTACAGCCAACATCGAAGTTAAAATGGAAGAGGTGGTCGATGATGAAGACTCGAGTACAAATAAAGTGTTAGACAAAGAGTCCAACACAGATGTCACAATTGTAGAGAGCAGAAAAGAAGCAGACGAAACGTTGAGTGAATCTGGTGTCAATTTAAGAAACACAAGTGAGAAACATGAGAATAAATGCAATATTCGCAATAAAACTTTTGAACGCAAAGGGAACCTAAAAAATCATCTCAAAACTCACGAGGGCTACAAATGCCAAATATGTCCAGAAATATTGTCTAATCAGATAGAGTCCGATAAACACATGAAAATACACCCGGGCAGAATAATACACGAGTGCCAAGATTGCGGTCGGACATTCGTAACCAAGACAAACTTGCTGAACCATTGTCAAAACGTGCACATGGGTGTAAAACCGCATGTGTGCGAACAATGTGATAAATCGTTTAGTAGTAAAAGAGCCTTACACACACATAATGCAGTGCATTTGGCACTTAAGCCTAACACTTGTAACGTGTGTGATAAGAGGTTCACAAGCAAAGCATATTTAAAATCACACATGTTGACGCATACTGGGATAAAATGTTTCCAATGCGGTGTCTGTAGCAAGACTTTTGCGCTAAAACATCAACTCAGTAGACACATGGGGGGGGTCCATAATAACGGAAGACCCTACGAGTGCAACACGTGCAAAAAGTTTTTTAAATTCAAGCAGTCTTTGCGCAAGCACATATCGGCTGTACATTTGGGCTTTACGTGTGAATGCGACATATGTAAGAAGATATTTAAATACAGGGAGAACATGCTCAAGCACATGTCGGCTGTTCATTTGGGCTTTAAGCCAACGCCCACTGAGTGTGAGATTTGTAAGAAGACATTTACATCGAAGGGGAATATGCGCAAGCACATGTCGGCTATACATTTGGGCTTTACATATGAGTGCGACATTTGCAAAAAGACATTTAATTACAAACCGAATTTACGCCGCCACATGTCTGCAGCACATTTGGGCTTTGCAAATAAGTGCGACATTTGCAAGAAGCCATTTACATCGAAGGCGTATATACGCAAGCACATGTCGGTTGTACATTTGGGCTTTACGTGTGAATGCGACATCTGTAAGAAGATATTTAAATACAGAGGGAACATGCTCAAGCACGTGTCGGCTGTACATTTGGGCTTTAAGCCAACGCCCATTGAGTGCGACATTTGTAACAAGACATTTACATCGAAGGGGAATATACGCAAACACATGTCGGCTGTACATTTGGGCTTTAAGCCAACGCCCACTGAGTGCGACATATGTAAAAAGACATTTGCATCGAAGGTGACTATACGCCGCCACATGTCGGTTGTACATTTGGGCTTTAAACCAACACATTAA
Protein Sequence
MDAARQRGLEEPEEGTDAELLPTAAPSSSPSMDLAALLAAVQSIQASQEAARREQEAAVQRIQAIQEAARREQEAAVQNIQASQEAARREQESTSQMLLSKLDTSLEAICDKVKQVESEVKGVSLKFEGLEERLDQTDSRHQALAEKVQKLMTREAVLTAPVPTQGRLDLPRDPGLISGKVGSRLDLDSSSICISGSGGNNHPLQKTFVKEQHVCCCVSFVPFKDKNIYTICDKCIEKLRISMEFKNCVLACKNNACWRGHCSARLDGGTAVTPDINQNTSKDKDSDTDIINKVLDKESTEEVKVEETFSESEEFTANIEVKMEEVVDDEDSSTNKVLDRESNTDVTIEESRKEADETLSESENTSKDKDSDMDIINKVLDKESTEEVKVEETFSESEEFTANIEVKMEEMVDDEDSSTNKVLDKESNTDVTIEESRKEADETLSECENTSKDKDSDMDIINKVLDKESTEEVKVEETFSESEEFTANIEVKMEEVVDDEDSSTNKVLDKESNTDVTIVESRKEADETLSESGVNLRNTSEKHENKCNIRNKTFERKGNLKNHLKTHEGYKCQICPEILSNQIESDKHMKIHPGRIIHECQDCGRTFVTKTNLLNHCQNVHMGVKPHVCEQCDKSFSSKRALHTHNAVHLALKPNTCNVCDKRFTSKAYLKSHMLTHTGIKCFQCGVCSKTFALKHQLSRHMGGVHNNGRPYECNTCKKFFKFKQSLRKHISAVHLGFTCECDICKKIFKYRENMLKHMSAVHLGFKPTPTECEICKKTFTSKGNMRKHMSAIHLGFTYECDICKKTFNYKPNLRRHMSAAHLGFANKCDICKKPFTSKAYIRKHMSVVHLGFTCECDICKKIFKYRGNMLKHVSAVHLGFKPTPIECDICNKTFTSKGNIRKHMSAVHLGFKPTPTECDICKKTFASKVTIRRHMSVVHLGFKPTH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-