Basic Information

Gene Symbol
-
Assembly
GCA_936447275.2
Location
CAKZFQ020000721.1:108235-112215[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 3.7e-06 0.00023 21.8 3.6 2 23 114 135 113 135 0.98
2 16 0.00097 0.06 14.2 0.9 1 23 138 160 138 160 0.97
3 16 3.2e-05 0.002 18.9 0.8 1 23 166 188 166 188 0.99
4 16 0.11 6.8 7.7 0.1 5 19 195 209 193 209 0.95
5 16 0.0015 0.095 13.6 0.2 1 23 218 240 218 240 0.97
6 16 1.8e-05 0.0011 19.6 1.0 1 23 246 268 246 268 0.98
7 16 0.18 11 7.0 0.1 8 23 310 326 303 326 0.84
8 16 1e-05 0.00064 20.4 0.9 2 23 334 356 333 356 0.94
9 16 1.9e-05 0.0012 19.6 2.6 2 23 363 385 362 385 0.93
10 16 0.0002 0.012 16.4 0.8 2 23 392 414 391 414 0.93
11 16 0.18 11 7.0 0.1 8 23 427 443 420 443 0.84
12 16 3.3e-06 0.00021 21.9 1.8 2 23 451 473 450 473 0.94
13 16 3.8e-06 0.00023 21.8 0.9 2 23 480 502 479 502 0.96
14 16 1.1e-05 0.00067 20.3 0.9 2 23 508 530 507 530 0.94
15 16 8e-06 0.0005 20.7 1.5 2 23 538 560 537 560 0.94
16 16 0.00011 0.0068 17.2 0.5 2 21 567 586 566 587 0.95

Sequence Information

Coding Sequence
ATGGCAGTCGACGTCAAAGTTCAAAGAGAAGAGACTGCCAATGATGAACACAGAGACATAGCCATAAATAGCGTATTAGATGAAGAGTCCGATGAAGATGTCACAATTGAAGAGAGCAGAAAGGAAACAGATGCAACCTTGTGTGAATCTGAAGTACCGTTGATTAAACTCTACATAAAAGTTGAAAAGGAAGAGCCTCCCACTCACAACAATGAAGACAATCACTCAGATGTAAATGTGGTTTTAGACGAAGTATCCAATCAAGATGGCAGAATTGAAGAGAGCCGAAACGAATTAGATGAAAACTTCAGTGAATCTAAGAACGACAGACACGAGAATAAATGCAATATTTGCAATAGAACTTTTAGATTCAAAAAGTACCTAGAAAGTCACATGAAGACGCACTTTAGACATCGCTGTGAAGTATGCAATAGAGATTATCAGAGCAAAGGTGAATTGCTTAGACACGAAATGGTGCATAAGGATGAGAGAAAGTTTAAGTGCTCGATATGTAATAATGGGTTTACACTGAGCAGAAGTTTGAAGGCTCACATGGAAACACACAAGGATGAAACACCGCAGGAGTGCGGCCGGAAATTCAATGTCAAGAAAAGCTTATTGAGGCATCCTCAAAACATGGGTGTAAACAAGTACAGTTGCCAGTATTGTGATAAAGGATTTATGATGAAAGGTAGATTGGTTGCACATGAAATGATACACACGGACGTAAAACAATACGAGTGCGAAAAATGCAATAAATCGTTTAGAAGCAAAGATGTTTTGATAAGTCATAATAAAGTGCATGAGAAACATGAGCCTAACAATTGTAACCTGCGTGAAAATGGATTCAAAAGAAGAGAAAATTTCAATAGACAAATTTCGGCTGTACATTCGGACCTTCCACCCACTCAGTGCGACATTGGCATGAAGACATTTCAATCCAAGTCTAATATACGCAAGCACATGTTGGCTGAACATTTGGGCCTTAAGCCACCCACTCAGTGCGATATTTGCAAAAAGGCATTTAAATATAAACAGAGTTTAAGCAGGCACATGTTGGCTCTACATTCGGACCTTCTACACACTCAGTGCGACATATGCAAGAAGACATTTAAATACAAACATAGTTTAAGCAGGCACATTTCGGCTGTACATTCGGACCGTCTACACACTCAGTGCGACATTTGCATGAAGACATTTAAATACAAACAGAATTTAAGCAGGCACATTTCGGCTGTACATTCGGACCTTCCACCCACTCAGTGCGACATTGGCATGAAGACATTTCAATCCAAGTCTAATATACGCAAGCACATGTTGGCTGAACATTTGGGCCTTAAGCCACCCACTCAGTGTGATATTTGCAAAAAGACATTTAAATATAAACAGAATTTAAGCAGGCACATGTCGGCTCTACATTCCGACCTTCTACACACTCAGTGCGACATATGCAAGAAGACATTTAAATCCAAGGAAAATATACGCCAGCACATGTTGGTTGTACATTTGGGCTTTAAGTTAAAGTGTGACATATGCAAGAAGACATTTAAATACAAGCAAGGTCTACGCAGCCACATGTTGGCTGAACATTTGGGCCTTAAGCCACACACTCAGTGCGATATTTGCAAAAAGACATTTAAATATAAACAGAGTTTAAGCAGGCACATGTCGGCTGTACATTCGGACCTTCCACCCACTCAGTGCGACATTTGCAGGAAGACATTTAAATCCAAGGAGACTATACGCAAGCACATGTTGGCTGTGTTGTGTACTCTTAGCTTTTTAGCTACAGGGTCGTACCAAAGGGTTGTTAAGGCCCTCAACCATAATTGTATGGTCATCAGTCGGATACTGTTTCTACAAACACCACAAGAGAGGTCCCTAGTCAAGGAGAATCTATCGCCTCGTCGCAACGATAGAAACTTAGCCAAGCGTTATTCGTCAGTCCCTGAGTCGACTGTCCGCACACAATGGCGCCGCCGTCCAAAACAGAGGGGAATATATCGCACCCTGGCGGTCAGCCAGTCTAGTACAGGCGTCTCACAGATTCTATCAATCGCTGTCGAAGAGACCCGATCCTTGCCGATCGCATTCGCACAGGCGCTTACGCTTCGCTTTTTCAAGTCAATTTCTTTCAGGACGCGACATATTTATATGGAAAATTGTCAGATGTGTGATTATGACTTAAAATTTATAAATGTAAACTCAAAATTTGGTGGAGCCACACATGACTCCCACATATGGTCCTTGCCTTGCCCAGTTTAG
Protein Sequence
MAVDVKVQREETANDEHRDIAINSVLDEESDEDVTIEESRKETDATLCESEVPLIKLYIKVEKEEPPTHNNEDNHSDVNVVLDEVSNQDGRIEESRNELDENFSESKNDRHENKCNICNRTFRFKKYLESHMKTHFRHRCEVCNRDYQSKGELLRHEMVHKDERKFKCSICNNGFTLSRSLKAHMETHKDETPQECGRKFNVKKSLLRHPQNMGVNKYSCQYCDKGFMMKGRLVAHEMIHTDVKQYECEKCNKSFRSKDVLISHNKVHEKHEPNNCNLRENGFKRRENFNRQISAVHSDLPPTQCDIGMKTFQSKSNIRKHMLAEHLGLKPPTQCDICKKAFKYKQSLSRHMLALHSDLLHTQCDICKKTFKYKHSLSRHISAVHSDRLHTQCDICMKTFKYKQNLSRHISAVHSDLPPTQCDIGMKTFQSKSNIRKHMLAEHLGLKPPTQCDICKKTFKYKQNLSRHMSALHSDLLHTQCDICKKTFKSKENIRQHMLVVHLGFKLKCDICKKTFKYKQGLRSHMLAEHLGLKPHTQCDICKKTFKYKQSLSRHMSAVHSDLPPTQCDICRKTFKSKETIRKHMLAVLCTLSFLATGSYQRVVKALNHNCMVISRILFLQTPQERSLVKENLSPRRNDRNLAKRYSSVPESTVRTQWRRRPKQRGIYRTLAVSQSSTGVSQILSIAVEETRSLPIAFAQALTLRFFKSISFRTRHIYMENCQMCDYDLKFINVNSKFGGATHDSHIWSLPCPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01386018;
90% Identity
iTF_01386018;
80% Identity
iTF_01386018;