Basic Information

Gene Symbol
-
Assembly
GCA_027564815.1
Location
JANTOP010033338.1:14310-19673[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.016 0.58 10.8 1.6 2 23 231 253 230 253 0.97
2 19 0.0026 0.091 13.4 0.2 2 23 260 281 259 281 0.94
3 19 0.11 3.8 8.3 2.4 1 23 287 310 287 310 0.95
4 19 5.3e-06 0.00019 21.8 0.4 1 23 315 338 315 338 0.98
5 19 0.00015 0.0052 17.3 1.5 2 23 344 366 343 366 0.96
6 19 0.0011 0.038 14.5 0.5 3 23 374 395 373 395 0.96
7 19 1.8 64 4.4 0.3 2 23 403 425 402 425 0.93
8 19 0.00021 0.0073 16.8 2.6 3 23 434 454 432 455 0.94
9 19 1.6e-06 5.6e-05 23.5 1.2 1 23 460 482 460 482 0.98
10 19 0.0013 0.046 14.3 1.3 1 23 489 512 489 512 0.98
11 19 0.0091 0.32 11.6 0.2 2 23 703 724 702 724 0.94
12 19 0.0042 0.15 12.7 1.9 1 23 730 753 730 753 0.95
13 19 2.7e-05 0.00094 19.6 0.8 1 23 758 781 758 781 0.98
14 19 0.0002 0.0072 16.8 1.0 2 23 787 809 787 809 0.97
15 19 0.0012 0.043 14.4 0.5 3 23 817 838 816 838 0.96
16 19 0.058 2 9.1 0.6 2 23 846 868 845 868 0.96
17 19 9.9e-05 0.0035 17.8 2.7 1 23 875 898 875 898 0.96
18 19 3.3e-05 0.0012 19.3 0.1 1 23 903 925 903 925 0.97
19 19 0.0013 0.044 14.3 4.7 1 23 932 955 932 955 0.97

Sequence Information

Coding Sequence
ATGCCGAGAATTTTGTCTGGAAAAAGAGTATATGAACAGTGTAAATTGACTAAGGAATTGAATTGCTGTTGGTACTTGGTGATAAAACAGAATTCATCGGAGATAAACATCAACAGTCATTCGGATGAAAAAATGGATACAAAAATTTGTATTTTGTGTTTAACTAATCCCGATTTCGAAAATTACAAATCCTTGTTCCCAACAAAAATCGGAAATGAGAGTTTGAACGAAGTTTTACGATTACATTTCTGGGAGGTACAGGTGAATGAACGGATAATTATTATGTGCAAATCCTGTTTGGAAAAGGTCACTACTTTCCATGAATTTTATTTGGAAGTGCGAACAATTCACGATCAATTTGAGGAACAGAAATTAGCGAATACTATTTTCTGTGAAAATATTATCAAGGTAGAGCCGGAACTGGACATTCCTATAAACAATTTATCGGATAATGTTGAAAATGATACATTGGATATGCCGGACGAACAGATTGAAAGTAAATTCGATGTGGGAAAACTTGTGGGTAAATCGGATAAGGAGGAAAGTCCAAAACCATGGTCGGGATCCAAGAAAGTGAAGAGAAAACCATCAAATGAATTAACGACTAGAAAATCGAAAGATGCTAAACCGGAGAATTGGAAATTAATCTTGGAAAAGAATTATGAGAAATTTCTACTGCGATTCTTGATGAAATGTCAATTATGTTCCGTCTGCTTCGCATCTTTGGACGATGCCCGAAAACATTACCGCTCTGATCACAATTGTAGAGGTTATTTGGTGTGTTCGGATTGTGACCGACGGTTTTCCAATTACAAACAAATTGTTGATCATTTAGAATGGCATGAAGATTCGGAGAAATTTATATGTACAACATGTAATAAAACATTCTTAGACGGTACTCGTTTGAGAACACATATACGGCACATCCATGGGGATAGAATGTACAAATGTGATCAATGTGATGCGACATTTCCACGTCAGAATGCCTTAACATATCATATGCAGACCGTACATTCAGAGATTGAAATGGAATGTAATCAATGTAAAAAGAAATTTAAATCCGACGCATCATTACGCTATCATATTAGGAAAGTTCATGAAAATTCTGATTCCCGTATATGTGACATATGTGCGAAATTCTTTAAAAATTCTACAAACTATGAACTTCATTACAAAGTCATGCATACAAACACAATTCAGAAGGTGCAGTGCGATATATGTGGATCCTGGTTAAAACATATCGGTATGCTGAAGGAACACATGAATTATCAACATAAACTACCAAATGTACCACAAATTTGTAAATATTGTGGAAAAACTGCGACCAATCGTAAATTGTTAATGAATCACATCCGATTTCATCATTCAAATACTTCCTACACTTGCCAAATTTGTGATAAATCGTTTAAACAATCGAAAAGATTAAAGGAGCATATGGCTGTACATTCGGGCAACAAGGAACTGTATACATGTAGTTTTTGTCCGAAAACACTACGATCAAGTGATTCCATGTATGCACATCGAAAGAAAGCGCATCCGGTCGAATATCAACAATCCAAACAACTTAAAATAGATAAAATTAAAGTGAATGAACGGATAATTATTATGTGCAAATCCTGTTTGGAAAAGGTCACCACTTTCCATGAATTTTATTTGGAAGTGCGAACAATTCACGATCAATTTAAGGAACAGAAATTAGCGAATACTATTTTCTGTGAAAATATTATCAAGGAAGAACCGGAACCGGAGCTCTCTATAAACAATTTATCGGATAATGTTGATTATAATACGACGGAAACACCGGACGAACAGAATGAAACTAAATTCGATGTGAACAAAGGTGTCAGTAAATCGGATAAGGAGGACCAAACCAATCCAAAACCAAGTTCGAGATGCAAGAGAGTTAAGAGAATACCATCCAATGACTTAAAGACGGAAAAATCAAAAGATGCTAAACCCGAGAGTTGGAAAACAATTTTAGAAAGGAATTATGAGAAATTTTTACTTGGATTCTCGATGCAATGTCAACTATGTTTGGTATCCCTTCAATCATTGAACGATGCCCGAAAACATTACCGTTCCGAACACAATCGTAAAGGTTATTTGGTGTGTTCGGATTGTGAACGACGATTTTCCAATTACAAACAAATTGTTGATCATTTAGAATGGCACGAGGATCCAGACAAATTTATATGTACAACATGTAATAAAACATTCGTAGACGGTACTCGGTTAAGTAAACATATACAGCATATCCATGGTGATAGAATTTACAAATGTGACCAATGTGAAACCACGTTTACACGACAGAATCCCTTAATATACCATATGCAGACCGTACATTCAGAGAACGAAAATGAATGTAATCAATGTGAAAAGAAATTTAAATCCGACGCATCATTACGCTATCATATTAGGAAAGTTCATGAGAATTCTGATTCCCGTATATGTGACATATGTGCGAAATTCTTTAAGAATTCCAAAAACTATGAACTTCATTACCAAGTTATGCATACGAATACAATGCAAAAGGTCAAGTGCGATATATGTGGATACTGGTTGAAGCATTACGGTATGCTAAGGGTGCACATGAATTATAAACATAAACAACCAGATGTACCACATATTTGTACATATTGTGGGAAAACGGCGACCAATCGTAAATATTTATTGAATCACATTCGACGTCAACATTCAGATATTTCCTTCCCTTGCCAAATTTGTGATAAATCGTTTAAATATGCGTTAGCATTAAAGGAACATATAGCTATACATTCGGGTAACAAGGAACTGTATACGTGTGGTTTTTGTCCGAAAACATTCCGATCAAGAGCTAACAAGTGTAAACATCGACAGAAAGCGCATCCGGTCGAATATCAACAATACAAAGATCTTAAAATGGCTGGAATTGATGTCAACTAA
Protein Sequence
MPRILSGKRVYEQCKLTKELNCCWYLVIKQNSSEININSHSDEKMDTKICILCLTNPDFENYKSLFPTKIGNESLNEVLRLHFWEVQVNERIIIMCKSCLEKVTTFHEFYLEVRTIHDQFEEQKLANTIFCENIIKVEPELDIPINNLSDNVENDTLDMPDEQIESKFDVGKLVGKSDKEESPKPWSGSKKVKRKPSNELTTRKSKDAKPENWKLILEKNYEKFLLRFLMKCQLCSVCFASLDDARKHYRSDHNCRGYLVCSDCDRRFSNYKQIVDHLEWHEDSEKFICTTCNKTFLDGTRLRTHIRHIHGDRMYKCDQCDATFPRQNALTYHMQTVHSEIEMECNQCKKKFKSDASLRYHIRKVHENSDSRICDICAKFFKNSTNYELHYKVMHTNTIQKVQCDICGSWLKHIGMLKEHMNYQHKLPNVPQICKYCGKTATNRKLLMNHIRFHHSNTSYTCQICDKSFKQSKRLKEHMAVHSGNKELYTCSFCPKTLRSSDSMYAHRKKAHPVEYQQSKQLKIDKIKVNERIIIMCKSCLEKVTTFHEFYLEVRTIHDQFKEQKLANTIFCENIIKEEPEPELSINNLSDNVDYNTTETPDEQNETKFDVNKGVSKSDKEDQTNPKPSSRCKRVKRIPSNDLKTEKSKDAKPESWKTILERNYEKFLLGFSMQCQLCLVSLQSLNDARKHYRSEHNRKGYLVCSDCERRFSNYKQIVDHLEWHEDPDKFICTTCNKTFVDGTRLSKHIQHIHGDRIYKCDQCETTFTRQNPLIYHMQTVHSENENECNQCEKKFKSDASLRYHIRKVHENSDSRICDICAKFFKNSKNYELHYQVMHTNTMQKVKCDICGYWLKHYGMLRVHMNYKHKQPDVPHICTYCGKTATNRKYLLNHIRRQHSDISFPCQICDKSFKYALALKEHIAIHSGNKELYTCGFCPKTFRSRANKCKHRQKAHPVEYQQYKDLKMAGIDVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-