Basic Information

Insect: Sycophaga agraensis
Gene Symbol: Zfhx4
Assembly: GCA_018906755.1
Location: JACCIE010000128.1:195715-227093[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.019 2.4 9.2 2.2 2 23 122 144 121 144 0.94

2 13 0.01 1.3 10.0 2.5 3 23 165 186 164 186 0.95

3 13 0.0019 0.24 12.3 3.4 2 23 249 271 248 271 0.95

4 13 0.0028 0.35 11.8 1.3 1 23 288 310 288 310 0.97

5 13 0.0017 0.21 12.5 1.3 2 23 317 339 316 339 0.96

6 13 0.18 23 6.1 5.6 1 23 428 452 428 452 0.90

7 13 0.0044 0.57 11.1 0.6 1 22 472 493 472 496 0.89

8 13 0.0062 0.79 10.7 0.3 1 23 536 560 536 560 0.92

9 13 0.041 5.2 8.1 0.2 2 21 606 625 605 626 0.94

10 13 0.35 45 5.2 2.0 2 19 773 790 772 795 0.91

11 13 9.5e-05 0.012 16.4 2.5 1 23 1356 1378 1356 1378 0.99

12 13 0.00042 0.053 14.4 0.7 1 23 1463 1485 1463 1485 0.98

13 13 0.004 0.51 11.3 0.3 2 23 1627 1649 1626 1649 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.019	2.4	9.2	2.2	2	23	122	144	121	144	0.94
2	13	0.01	1.3	10.0	2.5	3	23	165	186	164	186	0.95
3	13	0.0019	0.24	12.3	3.4	2	23	249	271	248	271	0.95
4	13	0.0028	0.35	11.8	1.3	1	23	288	310	288	310	0.97
5	13	0.0017	0.21	12.5	1.3	2	23	317	339	316	339	0.96
6	13	0.18	23	6.1	5.6	1	23	428	452	428	452	0.90
7	13	0.0044	0.57	11.1	0.6	1	22	472	493	472	496	0.89
8	13	0.0062	0.79	10.7	0.3	1	23	536	560	536	560	0.92
9	13	0.041	5.2	8.1	0.2	2	21	606	625	605	626	0.94
10	13	0.35	45	5.2	2.0	2	19	773	790	772	795	0.91
11	13	9.5e-05	0.012	16.4	2.5	1	23	1356	1378	1356	1378	0.99
12	13	0.00042	0.053	14.4	0.7	1	23	1463	1485	1463	1485	0.98
13	13	0.004	0.51	11.3	0.3	2	23	1627	1649	1626	1649	0.96

Sequence Information

Coding Sequence: ATGGAAATCTCTTTAGGTTCACCCCTAAACGGCAGATCAGATGTATCAGATGTTCAGGCGCCTGATGCGTCTGCGGGGTGGCTCAAGTTTTCTAACAAACAAGCTACAACTGCGGGTGCATCTGGAAATGGGCCTGTAGGTTCTGAAAGGAACCCGCCATCCTGCCTGAATAGAGAGATGCGCACCGAGATGGGAATTAGATCATTCTCTATTCAAGGTGCTCATCTATGGAACAAACAGGTCATCCTTCCATTAATTTATGTTACAGAACATCGTGACAATGAAAATACATGTGAAAATGTTATAAAAAAAGAAGAAGCACAGGAACAAATGCAAGACCAGGAAAATGAAACCGAAGAAATTGTATGTTCTTATTGTTCGTATCAGTCAACGTCTCACGATGATTTAAGACACCATCTCCAACTGGTCCATACTCATGAATTTGATGAAAACATTGAGAATTTAAAAGATGGTTCAAATTTAGATTTATTGTGTCCTTTATGCCAAGATTGTTTTAAACATCGTTCTGCTTTAGAAAAACACGTAATGCAAATTCATTCAGTTAATTCGGATGGTTTACAAAGATTGCTCCACCTTGTAGATCAAAGCCATTGGTTAAATAATAATCCTCGAAGTTTAAATGCCTCAATTCCATGCCCAACGTCTCCAAATATGCTGTTTAGTAAAAACCAAGAAATTGAAAATATAGAACAAACTACTTGCGATGATAGTGATGATTGCATGAAATGTACAGTTTGTCCACGTGTATGTCGTTCATCAGAAGAGCTTCAACAACATCATAAAGAATCACATTCAGCATCTTTACCTACATTAGCTGTGAGTGAAAAACATGTTTATAAATATAGATGTGGACAGTGCAGTTTGGCTTTCAAAACACTTGAAAAGTTGCAACAACATTCACAATATCACGCTATAAGGGATGCTACTAAATGTGCTATATGCTTTCGATCATTTAGATCTGTACAGGCTCTTCACAGACATTTAGAAACTGCTCACGCAGAAATACAAGAAGATGAATTAGCACAATATAAGCAAAGTTTGATAAATTCTCATCCACTTTTGCAAGCACTGACTGAAGAAGCTCTTCGTCGACAAAATGTGTTTAATAGCGAACCAATTATTGATGATGAAACCAAATTAGATGAAGATATCAGCGAAGTTAATGATTCTACTCCATTACAGAAGGAACGTCGCTTATTTGAAGATTACCTTAATAGCCAATCTATTGCGGAAGATTCATATAATGATCCAGGACGAAAATTTAAATGTCATAGATGTAAAGTTGCTTTTACAAGACAATGCTATCTTTCAGGGCATAATAAAACACTTTTACATAGAAAAGGTGAAAAAATGCCATATCCAATGGAAAAATATTTAGACCCAAATAGACCATATAAGTGCGACGTTTGTAAGGAAAGTTTCACACAAAAGAATATACTTCTTGTTCACTATAATAGTGTTAGTCATCTACATAAACTCAAAAGGGCTATGCAAGAGCAAGGTAATAACAATTCATTTATAAATGTATCGCCCCTAAGTCCAACCGATACTAGTGATAATCTACTAGATCAAGATAAAAAACCGTATAAGTGCAATATATGTAAAGTAGCTTATTCTCAAGGAAGTACTTTAGATATTCATAAAAGAAGTGTACTTCATCAAACTCGTGCTAGTAAAATTCAGGATTTATCTGTTAGTGGACAATTGGATATTTCACGTCCTTTAATTGAGCAAGCTGCTTTGAGTCCTAATAGTTCTTATAATATAAATTCAGACACTAATAGTCGTATGATATCTTGTTCGAAATGTAATGCGTTATTCATGAACCAAGACCAACTTTCTAATCATCAACAATTGTATTGTATTTTCACTAACCCTCTTGCAATATTTCAACAACTAGCAACCTCTCAACAGTTAGCATTAACAGAGACAAAAACTCCCCCTCCTTCAGTTACATCTACAGGATTACAAGAAAAACCAACTCAACAATCAAACTATCAATCAATAATATCGGCTCAAGATGTTTTATACCAACCAAAACACAAAACATCACATATGTATAAACATTTATTGGAAAGCTTTGGTTTTGACTTAGTTATGCAGTTTAATGAGAATCACCAAAGAAGACAAAGAAAAGAAGTTGAAGACGAGGAAACTATAGTTTCATATCAATTACATGAACATAATCGTAATTTAGAACAGCAAAATCATAGCTTTGATGATCAAATTTGTCAAGAAAAACATGACACAGAAGATATAGGAGAAGAAGAAATTATTCCAGAAATAAAAAAAAGTACCTGTCAACATTGTAGTAAGGAATTTAGCAGTGTCTGGGTGCTTAAAGCTCACTGTGAAGAAGTTCATCGTGATTTGGTTCCTCGAGAATTTTTAGAAAAATATGCACAACAATTTAAATGTGAATATGAAAAAAAAATTGTTATTGTTACAGCGGCGACATCTTCTTCAACGACTACTGCGCCTGTTACTACGACACCTACATCATTTCAATCTCAAGATAATTATACAGTCGAAAATAAAGAAAAAGAGAACTTATCTGAAAGCAAAGAACGACTTAGTAAAACACCAGAAGCAACTTCTACAACACCTACGACTACACCAATATTAAGCAATACACCAGTATCAAGCACAGACTCAATGACATCAAATTCAACAAGTCATATAACACATAATCTGATTCAGCAACAACAGCATCAGGCACAATTAACATTAGCTCAGCATATGTCTGAAATGCAAGCTGCATTTAATGCAATGGCTGCATCACAATTACAGCAACAACTTCATCAATATCCTAGTTTAATGATGAGTATGATGGGATTGCCTTTAGGTTTAAATGTTCCTGCTCTGGCGGCTATGAATCTTCAACCCCCACTAGTACCAATAATGTTGCCGCCGTCACCATTTGATACAAACACAAGTACATATTCTTCTTTACCATCGCAGTCAGATATAGTAACGAAACAACATATAACGTTACAACAGCAACAGCACACAATTGTAAACGTTGGAACATCACAAAAACGTGCTCGCACTAGAATAACAGATGATCAATTGAAAATACTTAGAGCCCACTTTGATATAAATAATTCTCCTGGAGAAGACCAAATTATTGATATGGCATCTCAAAGTGGATTACCACCTAAAGTAATAAAACATTGGTTTCGTAATACTCTATTTAAAGAGCGTCAACGAAATAAAGACAGTCCTTATAATTTTAACAATCCTCCAAGTACTACACTGAATTTAGAAGAATACGAAAAAACTGGTGAAGCAAAAGTAATACCACTTTCTTCTGTTACAAGTATAGATCACTCGGAACAAAAAAGTGATGATAAACAATTGCCTGAATCAGTGTCATTGGCAAATTCTAATACGAAAACACTTGGCGAAATTAAGCATGAGTATATAGATCAAAATATAATGCAACACTGTCAAGATGAACATCTTTCACCTGAAAGTTCCGGAGATCAACAGTCAAGGCCTCAATCTCCTGATATATCTCCTGTTTTTACTAGTGCTCATCAAGACATGTCAACAACATTTTCAACATCAATGATGTCACAAACAGCACCAATGCTTCCTCCAAAAATTACTCCTACCAATGTTGTTCCGAATTTACAGCTAGTCGGTACCTTGGCAACAAATACTTCTCCAGTATCGTTATCAAATCAGCAATGTACTAGTCCTGGTAGAATTTCTGATTTTTCATTTAATAGCAATAATGTTACTAGTAACCCGGGAAGTAGTAATTCAGGAAAAAGGGCAAATAGAACCAGATTTACAGACTATCAAATAAAAGTTTTACAGGAATTTTTTGAAAATAATGCTTACCCGAAAGATGATGATCTAGAATATTTAAGCAAGCTTCTAGGTTTAAGTCCTCGTGTTATTGTCGTATGGTTTCAAAATGCCAGGCAAAAAGCTCGCAAAGTTTATGAAAATCAACCTCAAACAGAACCTATTGCCTCTAGCGGACGTGAAGGCGATGATGGAACAGGCCGATTTCAACGAACACCAGGCTTAAATTATCAATGCAAAAAGTGTTTGCTTGTTTTTCAAAGATACTATGAACTCATACGACATCAAAAAACGCATTGTTTTAAAGAAGAAGATGCTAAACGAAGTGCTCAAGCACAAGCTGCTGCAGCTCAAGTAGCCGCTGTTCTCAGTTCTGAAGATAGTAATAGTAGTTCGACGACAACTAACACTTTACAATCAGCTTCTATAAATATTCAATCAATTTCAGAGCATTCTTCAAATTCAAATACAACATTTACTCCACAACAAAGTAGCCAGCAGCATCAATTAAATCAACAGTGTCTTCAATCAGAAACTAAAGATGAGAATTTTCAATGTGATAAGTGCAAGCTTGTTTTTAGTCGATTTGAATTGTGGCGTGAACATCAATTAGTACATATCATGAATCCAAGTTTATTTCCTTCAAACTATCCACCAGATTCAGCCTTTGGAATTCTTCAGCAGCAAGCATTAAATAATACTGCTTCAACTGCAGAAGTGCCTCATTCATTGCTTAACATGATGCAAGAAAGAAGAAGAAAGTATGAGGATTGTGAAGAAAGTCACATAATAGATAATAAATTTAATACAGAAAATAATGAGCAACCAAAAGATAAGCGTTTGCGCACAACGATCCTTCCGGAACAACTTGAATATCTGTATCAAAAATATCAAGTTGAATCAAACCCATCTAGAAAAATGTTAGAAACGATTGCTAGAGAAGTTGGTTTGAAAAAACGAGTAGTACAAGTTTGGTTTCAAAATACTAGAGCTCGAGAAAGAAAGGGTCAGTTTCGAGCTCATAGCCAAGTGATAAATAAAAGATGTCCTTTTTGTCCTGCACTATTTAAAGTCAAATCAGCTCTTGAATCTCATTTAAATAGTAAGCATACTGATCAAATTTCGAGGGGAGAAATAAATATTGATAACATTCCTGATGAAGAATTATCATTAGAATCATCTCCATCAAATCCGAGTACTCCGCAAATGATGCCTCCTCTGTTTCCTCCTATTAATACTGAAATAGAAGCATCTTTAAAAAAGTATTATGAAGAATCGATGAAACGATATATTAGCGAATTACAAGCACATTCTAGTAATGGTAAGCTGGATTCTAATTCATTCTTTGGAACAAATAGTGAGTCTCCATTGGATTTAAGTAAACCCGTTGACTTAAGCAAAACTGTGAATCTAACATTAAATAATTTTGGTAATGTGATAGATGATCAAAACAATGTTCAACAATTACGTAGCATTACAGATTGTGGCCCTCTAACAGATATTTCTGAAAAAAGTATTTGTGATGAAGATAGTATGAGTGAAACAACAGATTTTCTTGATGACGAGAGCAGACCAACTAGTCCTGCATCAAGTTCTCAAGGTTCTAAACAGGGATTGAGCAATAATACTTTTGGAAATAATACAATTTCATGTATTAGTGGAAATACAACAGTACAAAGTGGAGGAAAAAGATATCGAACTCAGATGTCTACAACACAGGTCAAAGTTATGAAATCATTGTTTTCAGATTATAAAACTCCAACAATGTCTGAATGCGAAATGTTAGGACGAGAAATTGGACTTCCTAAACGAGTTGTTCAGGTAGACACTGTGCACCGTGAGCCACCGCTGGGGAGTTCGAGGTGGCGTAGCCCTCCTACTATAAGGCCCGATAACGGGAATACACGCAGAAGGTCGGGGGACTTTCCCGGGCGGCTGCCAGAACTAAAGGACAGCAAGTCGCAACAGGAAAGGAGGCGCAGAAGAGAACCCGAGGAATCGAGAGGGAACCAGACATGTAGCAGCTGCGACGCGTGCAATCTCGAGAAAGATCTCGAAAGAGAAGTTAGTGGGGAACGCTTCAAAATCCTCCAACCCCTGGGCCCTATTTGGCATGATCTTATTCCTGCTCTATGCCCCATCGCGAGTCCCTCTACGAGGCGGCACGTACCGCTTTCGGTGCTGCACGTGCTCCTTATTCAATTTCGCCCCGAGTCTTCCAGAAAGACAACTGTCTGTCCCAGTACCCGTTTCACTTCAAATGGCCCGGCGTACTTGACGTCTAGTTTCTCGGAAACCCCCGGCATCGGACAGGGTATGCTCATATCGGAGCACCAGATCACCAGGTTGGAATGTGGCGTGACGCCAGTATCGGTTATAAGCCCGGGATCAATGGGAATAATCGGGCCCTTTCTTTCCATCTCTCTCATCAGGCTCCTGCTGGATCGTGGAATCCTCCCGAAATTCAGGACAACTGGGGAGACTCGAGCATACTGCCCTGGGCACAGAACCGGCTAA
Protein Sequence: MEISLGSPLNGRSDVSDVQAPDASAGWLKFSNKQATTAGASGNGPVGSERNPPSCLNREMRTEMGIRSFSIQGAHLWNKQVILPLIYVTEHRDNENTCENVIKKEEAQEQMQDQENETEEIVCSYCSYQSTSHDDLRHHLQLVHTHEFDENIENLKDGSNLDLLCPLCQDCFKHRSALEKHVMQIHSVNSDGLQRLLHLVDQSHWLNNNPRSLNASIPCPTSPNMLFSKNQEIENIEQTTCDDSDDCMKCTVCPRVCRSSEELQQHHKESHSASLPTLAVSEKHVYKYRCGQCSLAFKTLEKLQQHSQYHAIRDATKCAICFRSFRSVQALHRHLETAHAEIQEDELAQYKQSLINSHPLLQALTEEALRRQNVFNSEPIIDDETKLDEDISEVNDSTPLQKERRLFEDYLNSQSIAEDSYNDPGRKFKCHRCKVAFTRQCYLSGHNKTLLHRKGEKMPYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNSFINVSPLSPTDTSDNLLDQDKKPYKCNICKVAYSQGSTLDIHKRSVLHQTRASKIQDLSVSGQLDISRPLIEQAALSPNSSYNINSDTNSRMISCSKCNALFMNQDQLSNHQQLYCIFTNPLAIFQQLATSQQLALTETKTPPPSVTSTGLQEKPTQQSNYQSIISAQDVLYQPKHKTSHMYKHLLESFGFDLVMQFNENHQRRQRKEVEDEETIVSYQLHEHNRNLEQQNHSFDDQICQEKHDTEDIGEEEIIPEIKKSTCQHCSKEFSSVWVLKAHCEEVHRDLVPREFLEKYAQQFKCEYEKKIVIVTAATSSSTTTAPVTTTPTSFQSQDNYTVENKEKENLSESKERLSKTPEATSTTPTTTPILSNTPVSSTDSMTSNSTSHITHNLIQQQQHQAQLTLAQHMSEMQAAFNAMAASQLQQQLHQYPSLMMSMMGLPLGLNVPALAAMNLQPPLVPIMLPPSPFDTNTSTYSSLPSQSDIVTKQHITLQQQQHTIVNVGTSQKRARTRITDDQLKILRAHFDINNSPGEDQIIDMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVIPLSSVTSIDHSEQKSDDKQLPESVSLANSNTKTLGEIKHEYIDQNIMQHCQDEHLSPESSGDQQSRPQSPDISPVFTSAHQDMSTTFSTSMMSQTAPMLPPKITPTNVVPNLQLVGTLATNTSPVSLSNQQCTSPGRISDFSFNSNNVTSNPGSSNSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPQTEPIASSGREGDDGTGRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAAVLSSEDSNSSSTTTNTLQSASINIQSISEHSSNSNTTFTPQQSSQQHQLNQQCLQSETKDENFQCDKCKLVFSRFELWREHQLVHIMNPSLFPSNYPPDSAFGILQQQALNNTASTAEVPHSLLNMMQERRRKYEDCEESHIIDNKFNTENNEQPKDKRLRTTILPEQLEYLYQKYQVESNPSRKMLETIAREVGLKKRVVQVWFQNTRARERKGQFRAHSQVINKRCPFCPALFKVKSALESHLNSKHTDQISRGEINIDNIPDEELSLESSPSNPSTPQMMPPLFPPINTEIEASLKKYYEESMKRYISELQAHSSNGKLDSNSFFGTNSESPLDLSKPVDLSKTVNLTLNNFGNVIDDQNNVQQLRSITDCGPLTDISEKSICDEDSMSETTDFLDDESRPTSPASSSQGSKQGLSNNTFGNNTISCISGNTTVQSGGKRYRTQMSTTQVKVMKSLFSDYKTPTMSECEMLGREIGLPKRVVQVDTVHREPPLGSSRWRSPPTIRPDNGNTRRRSGDFPGRLPELKDSKSQQERRRRREPEESRGNQTCSSCDACNLEKDLEREVSGERFKILQPLGPIWHDLIPALCPIASPSTRRHVPLSVLHVLLIQFRPESSRKTTVCPSTRFTSNGPAYLTSSFSETPGIGQGMLISEHQITRLECGVTPVSVISPGSMGIIGPFLSISLIRLLLDRGILPKFRTTGETRAYCPGHRTG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01379835;
90% Identity: iTF_01379835;
80% Identity: iTF_01379835;