Smeg018319.1
Basic Information
- Insect
- Subacronicta megacephala
- Gene Symbol
- ZFX
- Assembly
- GCA_958496365.1
- Location
- OY292532.1:446029-455618[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.012 0.97 10.7 1.0 2 23 249 270 248 270 0.96 2 19 4.2 3.2e+02 2.7 0.1 6 23 282 300 282 300 0.93 3 19 1.6 1.2e+02 4.1 0.1 2 23 312 334 311 334 0.91 4 19 2.3e-07 1.8e-05 25.6 2.0 2 23 356 377 356 377 0.97 5 19 2.6e-06 0.0002 22.3 1.1 1 23 383 406 383 406 0.96 6 19 0.019 1.5 10.1 0.2 1 23 412 434 412 434 0.93 7 19 0.00027 0.021 15.9 0.6 1 23 440 462 440 462 0.98 8 19 0.51 40 5.6 3.5 1 23 582 604 582 604 0.95 9 19 0.00027 0.021 15.9 2.0 2 23 611 633 610 633 0.92 10 19 2.1e-07 1.7e-05 25.7 0.7 1 23 639 661 639 661 0.99 11 19 1.5e-06 0.00012 23.0 4.4 1 23 667 689 667 689 0.98 12 19 0.012 0.92 10.8 2.3 1 23 695 717 695 717 0.95 13 19 0.00016 0.013 16.6 2.9 1 23 723 745 723 745 0.96 14 19 0.57 44 5.5 1.3 2 23 795 815 795 815 0.95 15 19 1.6e-06 0.00013 22.9 0.4 1 23 821 844 821 844 0.96 16 19 2.4e-06 0.00019 22.4 1.7 1 23 850 872 850 872 0.97 17 19 0.0089 0.69 11.2 0.8 1 23 878 900 878 900 0.98 18 19 3.2e-05 0.0025 18.9 0.1 3 23 907 927 905 927 0.96 19 19 0.0087 0.67 11.2 0.2 6 23 937 954 936 954 0.98
Sequence Information
- Coding Sequence
- atggatgatgaaactgaacaaatatttatactaaATGTCGACGAGAGTCAGCCCTCTGGCTCTGTTCAGAAGCCGGACGACGTGGAAATAGAAATACCGGGCAGTTCACAGCACCTTGAAAatgtGGAAGACTTCTCACATGTGTGTCGGACATGTGCCACCGTTACAGAGTTTGTTATCCCCATATTTGCAGGAGAGGGGCTACAGAACAACTTAGCTGATAAAATACACAAACACTTACCAATacagGTGTGTGAGGAGGACTTGCTGCCGCGCGTGGTGTGCTACCAGTGCGCGAGCACCCTGCTGGCCTGGCACGAGCTGGTGCAGTGCTGTGTGCAGGCCGACGCCGCCCTGCGCGCAAGACTCGCGCAACAACAACAGGAATCAAATTCTACGAATTCAAAATCAGATGCAAACCTAAGAGAAGCCGACCAAAGCAAGTTGTTTTACACGCACGTCGAAAATGCTCTCATCGATTACTTTCCTAACACTCTGGATGAAAATAACTTAGATGTGGAGTTCGTTTGTCAAAAATGCGTCCCAAAGCCAAGCCTGACAAATATACAAAGGCTCGCGGAACATCTCCTTCGGGACCACTCTAACGACATAAGCGAACATAAAGCTATCAAAACGTTTATCACTAACTATATTACGTTCGAACAAGGGCTGGCTTCAGAGGATTCTGACAGAGAAACGCAATCAGTCGGTAAAGAAAAGTCTCGAACAGTTTTAGCGAGTTTGAACTGCCCGTTCTGTGCCAGCGTATTCTCGTCAGCGTCGCGACTCCTTCACCACCTGAACAAGCACATAGAAGTGTCCATCGCAGATGGCGTCAAGTGTTGTGACATCATTTACAACAATAAGAAACTCTTCGTGCAACATCTGCAGGACATCCACGTTGATAAGACCAACGACGATTCTGGTCAACTCGTGTGCGTCAGCTGCGAGTTCACGGCAGACGATGTTAAAGATTTAAGAAAACATTATAGAGAAGCACACAACGATCTAAAAACCGACAAAGTAAAGAAAGAGAGTCCAAACAACCAGAAACACATCCCTGCGGTGTGCCCCGAGTGCAACAAGACGTTTTCCAACAAATATAACATGTTTAAGCACATGAAGAGTCACGGCGCCACCAAGCTGTTCCCATGCGAAAAGTGCTCCAAGACCTACCGCACCCAGGGGAACCTGAACAACCATAGGCGATTAGCCCACGAAGGTATACTGAAGTTCCTGTGTCTGGAGTGTGGCGAAACGTTCCCATCACGTTCAGACCGCGATATACACTCGCGACTCCACACCGGAGAGAAACCGTTCAAATGCGAGTACTGTGGCAATTCGTATCGCGCTAAGAACACGCTCACCCAACACCTAGCGATACACTCAGACTTACGAAAATACATGAGCCCCTTTGACCCACACGATCTGGAGCCACGCGGATACACTGACAAATACTCCGACCAGTCCGATGATGAACCGCTGGCTACCCTCGCCACCAAGCCCACACACCTATACGACAACTTCTACAGAGCACTTGTTAATTTCAGAAACCATTTGGTCAATGATCAACATAAGGAAGATTATCCTGACTTTACTGACTCCAGTGTATCAGGCTCTGAGGGTAACGATGTGGACAGGTTCGATGACCTGTCGCAATGTAACATGAGGCGGGACAGACTAGATGAAGAGACAAGAACAGAACTAACTGAAGTACAGAACAAAGTTAACGAAAAAATTTACTACACTTGTAAGATTTGTAGCAAGAACCTGAGCTCTGCGCACACGTACTTGTTCCACAAACGAATCCACACTGGCGAGAGGCCGTGTGTGTGTCATATATGCGGCAAACAGTTCAGAGCGCCGAACGGTCTGCAGCGACACTTGACGGAAACGCACGAGCGCATCCGAAGATACACCTGCAGTATATGTCCGAAGAATTTCGCCAACTCACAGAATCTGAAGCAACACCTAAGGATACACACTGGAGAAAAGCCGTTCGTGTGTTCTCATTGTGGAAAGCGCTTCACGCAAAGTGGTTCCTTACACGTGCACCTAAAAACACACAGTGAACAGTTTCCTCACCATTGCGCGGAGTGCGGAGCCAAGTTTAGGCTGCGGTCAGGTTTGGTGAGGCATAGTCTGAAGCATACAGGGGAGCGGCCCCACGTGTGCGGCCAGTGCGGGAAGGGCTTCCGGCAGAGACACGAGCTCAACAGCCACAGCCTGTCGCACTCGGACGCGAAGCCCTACGCAATATTAACGGCCGATGAAGTGAAAGAAGATAACAGAGTTCCAGAAGACACCAAAACTGTAATTCAAGTTGCGGAACATATTGAAAAACCGGAGTTTACCGTCGGCGAGGACGGGAAGCGATATGCGAAGTGTAGAGTGTGCCACAAGAGTGTCTCTCTAAGGTCGTGGGCGAGACACGCGCGGATACACCGCGGAGAGAAGCGGTACAGCTGCCACACCTGCGGGCTCGCCTTCACCGACAGCGGGAACCTCGCGCGGCACACGAGAGCCGTGCACGCTAAGGAGCGACCGTTCGCCTGCCCCACGTGTCAGAAACGCTTCTCAAGGAAGGGGCACCTGGAGGAGCACGCGAGGTCGCACTCGGGGCGGCGCGCGTTCATGTGCGAGGTGTGCGGCGCCGCCTGCACGTCGGGCGCGGCGCTGCGCATGCACCGGCACACGCACGGGGCCCCCGCGCTGGCCTGCCCGCAGTGCGGCGCGCGCTTCAAGCGCCGCGGGGAGCTGCGCGCGCACGTGTCCGTGCACGAGGGCGCGCGCCCGCACGCCTGCGCCTGCGGGAGGACCTTCCGCCTGCGCGCGCAGCTCACCGCACACGAGCGCCTGCACTCCGACAAAACTATGCCGAACCTCGATACTATATTactagaaataaaacaataa
- Protein Sequence
- MDDETEQIFILNVDESQPSGSVQKPDDVEIEIPGSSQHLENVEDFSHVCRTCATVTEFVIPIFAGEGLQNNLADKIHKHLPIQVCEEDLLPRVVCYQCASTLLAWHELVQCCVQADAALRARLAQQQQESNSTNSKSDANLREADQSKLFYTHVENALIDYFPNTLDENNLDVEFVCQKCVPKPSLTNIQRLAEHLLRDHSNDISEHKAIKTFITNYITFEQGLASEDSDRETQSVGKEKSRTVLASLNCPFCASVFSSASRLLHHLNKHIEVSIADGVKCCDIIYNNKKLFVQHLQDIHVDKTNDDSGQLVCVSCEFTADDVKDLRKHYREAHNDLKTDKVKKESPNNQKHIPAVCPECNKTFSNKYNMFKHMKSHGATKLFPCEKCSKTYRTQGNLNNHRRLAHEGILKFLCLECGETFPSRSDRDIHSRLHTGEKPFKCEYCGNSYRAKNTLTQHLAIHSDLRKYMSPFDPHDLEPRGYTDKYSDQSDDEPLATLATKPTHLYDNFYRALVNFRNHLVNDQHKEDYPDFTDSSVSGSEGNDVDRFDDLSQCNMRRDRLDEETRTELTEVQNKVNEKIYYTCKICSKNLSSAHTYLFHKRIHTGERPCVCHICGKQFRAPNGLQRHLTETHERIRRYTCSICPKNFANSQNLKQHLRIHTGEKPFVCSHCGKRFTQSGSLHVHLKTHSEQFPHHCAECGAKFRLRSGLVRHSLKHTGERPHVCGQCGKGFRQRHELNSHSLSHSDAKPYAILTADEVKEDNRVPEDTKTVIQVAEHIEKPEFTVGEDGKRYAKCRVCHKSVSLRSWARHARIHRGEKRYSCHTCGLAFTDSGNLARHTRAVHAKERPFACPTCQKRFSRKGHLEEHARSHSGRRAFMCEVCGAACTSGAALRMHRHTHGAPALACPQCGARFKRRGELRAHVSVHEGARPHACACGRTFRLRAQLTAHERLHSDKTMPNLDTILLEIKQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -