Basic Information

Insect: Stomorhina lunata
Gene Symbol: ZEB2
Assembly: GCA_933228635.1
Location: CAKOFY010003660.1:237098-240039[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.13 8.8 7.5 0.7 1 23 326 349 326 349 0.95

2 11 0.076 5.2 8.2 2.4 1 21 424 444 424 445 0.95

3 11 1.1e-05 0.00076 20.3 1.6 1 23 453 475 453 475 0.98

4 11 0.0033 0.22 12.5 1.7 1 23 479 502 479 502 0.94

5 11 1.6e-05 0.0011 19.8 2.2 2 23 509 530 508 530 0.98

6 11 9.5e-08 6.4e-06 26.8 1.6 1 23 536 558 536 558 0.95

7 11 4.1e-06 0.00028 21.7 0.8 1 23 564 586 564 586 0.99

8 11 1.5e-05 0.00099 19.9 4.0 1 23 592 614 592 614 0.99

9 11 0.0059 0.4 11.7 0.3 1 23 620 642 620 642 0.98

10 11 0.0049 0.33 12.0 6.8 1 23 648 670 648 670 0.97

11 11 0.046 3.1 8.9 2.4 6 23 679 697 676 697 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.13	8.8	7.5	0.7	1	23	326	349	326	349	0.95
2	11	0.076	5.2	8.2	2.4	1	21	424	444	424	445	0.95
3	11	1.1e-05	0.00076	20.3	1.6	1	23	453	475	453	475	0.98
4	11	0.0033	0.22	12.5	1.7	1	23	479	502	479	502	0.94
5	11	1.6e-05	0.0011	19.8	2.2	2	23	509	530	508	530	0.98
6	11	9.5e-08	6.4e-06	26.8	1.6	1	23	536	558	536	558	0.95
7	11	4.1e-06	0.00028	21.7	0.8	1	23	564	586	564	586	0.99
8	11	1.5e-05	0.00099	19.9	4.0	1	23	592	614	592	614	0.99
9	11	0.0059	0.4	11.7	0.3	1	23	620	642	620	642	0.98
10	11	0.0049	0.33	12.0	6.8	1	23	648	670	648	670	0.97
11	11	0.046	3.1	8.9	2.4	6	23	679	697	676	697	0.95

Sequence Information

Coding Sequence: ATGAATACTGAGAAAATCTGTAGATGCTGCTTGGCCTTAGATGTGCCACTGTTGTCTATATATGATGGTGGCTCAGCTGGAATGGGATGTGTGGGTGATATGCTAAGGCAGATAGCAAAACTTAAGCCCCAGCCTGGTGATAAAATGCCCGAAAAGGCCTGCCTCCAGTGTATCAGTGAAATAAATCGCTGCTATGTCTTCAAAATGAAATGTGAAAATTCCAATAGAACTCTTAGGCAACTACTACCGGATGCAAAACCTGAGCTTTTAGATTTGGAAATTGTTAAAAATGTTAGTGTTGCCTCAGCCTCAGTACAGACAGATGATAAGATATTAACCACATCTACTATGCAAACGGACGAGATTGTAAAGCCTTTGGTAAGTCATAGTAGTGCTCAAACTATCGAGGAAGAAGGACCAATTGTAGGACACAAGGAAGTACAAACGGAATATGAGATTGTAGAAGAAGAATTTGAGAACACTAAAAACCATCAAGGCGACTTTGTTACGGAAAAGATTATCATATACGAAGAAATTGAAAAGCCCACAAAAAGCTGTAAGAAACGATTACAAACTTCGCCTTTAGGTAAAAGAGGAGCAAAAAAGAGAAAATCGGATACTGTTTTAAAATCTCAAGAATCGCCTATAAATAGTCAAACAACAGATGCCTATATACTACTCGAAGATTCTAATATAGAATCATTATCCCCAGTTGAGGCTGAAGCTGTTTATAATACAAACTCATTACAGCAGCAAGAAGATCAAGACAATAAACAACGTTTTGAATACTATGAAGAACAGATAGAGGAAATACCGGATAATGAATCAATACAAAATGTTATGTTTGAAGATGATCATGAATATGAAAATAACCTGACTAATAATGACTATGAGCCTGAAGAAGAAATCGAATATTCACAAAAGACCATaaaacccaccctcaataccagagcctctaacaaaactaaaggtctttataaatgttcccagtgcattatgacttttgtgagtataaaagttctgaagagacacttagccaatagacataatattaaagacgcggatattgtaatagattatctaactcctttggagcctgacaaaactgcaatagctgatgaagaaccttcttcatcagacaatgtggcaagtgtttttaatggcaatatttctgaattgacagccgaaaatgtggcaaaacctcaattaatgcctagggaaagagtaacatcgtctgtaaatGAGGAAATCTTACCAAGTAATATTAAATATTTCTGTGAATTTTGTCAGGCTGGATTTGCTCAACGTAAAACTTTTACTTATCATATGAAGCATCAAGTCTGTATGGTACATAATTTTAAGTGCAACAAATGCGATCGTATCTTTGTTTCCAAAGAAAATTTGGATACTCACAAACTTACACATGAAAATCCCCACAAATGCTTAGAATGTGATACTGTATGCAAAACTATGGAGGAACTTAGTCAACATATGATTGACGATCATAATAGAAATGCACGTAATCAATGTCACGTTTGCAAAAAAGTCTTTACCATGAAAACATctttaatagatcacttgcgtgtacacagcggcgaaaagcctttcctttgcacaatatgtggcaagagttttagccagaattccaatttacgccaacacttgacacgtcatacgaatgaaaaaaatttcaaatgtgatatgtgtcccaaagcttatgttacaaaggcggaattattttcccataaacgcacacacacgggtgagcatccgtttaaatgtgatatttgtgaggcccgtttcacaacatcgtgttcattacaaaaacatctacgcaaacatactggcgaaagaccatatgcctgtgaattttgtccctcacgttttgcttcactaaatgttttgaaaaatcatcgacgcatccacactggcgaaaagccttttaagtgtaaccattgccaaaaatcttttacccaaaaaggAGACTGTTTAATGCACGAACGTTCGCATGTCAATAAGGATTTTaaatgcttttgtgaagcaagattttataaaaaattcaacttaagaaatcacattaaaactcaacaccccgattttaatgaaaaagaaatacaatctttactcaATAAACAGCAAACAGAAAAGGCTGAATATCAAATAACCATAGTAGAGAGGGAATCTGATGGAAAATTTGTTGATGATGTTGCAACGGGAAATGTTGGATCTTCCAATAACAATGAAGATCTTATGCAAATTGCATTGGAAGATGTAGGTTAA
Protein Sequence: MNTEKICRCCLALDVPLLSIYDGGSAGMGCVGDMLRQIAKLKPQPGDKMPEKACLQCISEINRCYVFKMKCENSNRTLRQLLPDAKPELLDLEIVKNVSVASASVQTDDKILTTSTMQTDEIVKPLVSHSSAQTIEEEGPIVGHKEVQTEYEIVEEEFENTKNHQGDFVTEKIIIYEEIEKPTKSCKKRLQTSPLGKRGAKKRKSDTVLKSQESPINSQTTDAYILLEDSNIESLSPVEAEAVYNTNSLQQQEDQDNKQRFEYYEEQIEEIPDNESIQNVMFEDDHEYENNLTNNDYEPEEEIEYSQKTIKPTLNTRASNKTKGLYKCSQCIMTFVSIKVLKRHLANRHNIKDADIVIDYLTPLEPDKTAIADEEPSSSDNVASVFNGNISELTAENVAKPQLMPRERVTSSVNEEILPSNIKYFCEFCQAGFAQRKTFTYHMKHQVCMVHNFKCNKCDRIFVSKENLDTHKLTHENPHKCLECDTVCKTMEELSQHMIDDHNRNARNQCHVCKKVFTMKTSLIDHLRVHSGEKPFLCTICGKSFSQNSNLRQHLTRHTNEKNFKCDMCPKAYVTKAELFSHKRTHTGEHPFKCDICEARFTTSCSLQKHLRKHTGERPYACEFCPSRFASLNVLKNHRRIHTGEKPFKCNHCQKSFTQKGDCLMHERSHVNKDFKCFCEARFYKKFNLRNHIKTQHPDFNEKEIQSLLNKQQTEKAEYQITIVERESDGKFVDDVATGNVGSSNNNEDLMQIALEDVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -