Basic Information

Gene Symbol
-
Assembly
GCA_963583905.1
Location
OY757309.1:194072815-194073837[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.8 1.1e+02 5.7 0.1 2 23 81 102 80 102 0.90
2 9 0.5 70 6.4 2.2 1 23 108 130 108 130 0.95
3 9 0.016 2.3 11.1 2.7 1 23 136 158 136 158 0.90
4 9 0.00026 0.037 16.7 3.0 1 23 164 187 164 187 0.98
5 9 0.00026 0.037 16.7 1.5 1 23 199 222 199 222 0.96
6 9 3.3e-05 0.0046 19.6 0.3 3 23 233 253 231 253 0.97
7 9 1.1e-05 0.0015 21.1 0.1 1 23 259 281 259 281 0.98
8 9 0.0017 0.25 14.1 1.8 1 23 287 309 287 309 0.98
9 9 0.00064 0.091 15.5 0.1 1 19 315 333 315 335 0.87

Sequence Information

Coding Sequence
ATGGTGTGTACAGATAAATATTCCCACAACCACCACATGCTAAAAATGAGTAAGTTATttactacattttattttatactaaTTTTCGTGACCTTTGACACTCGTTTTGCTTTTAGGAAAAAAACTAGAAGAAAAAGGCGCGAGCCTTCCGAAAAAATTAAGAGACCACGGAAACCCAGACGCAACAAGGAGAAACCTAAAAAACAAGTGGTAGAGCCTATTAAATTGGAAGTGCCTTTACGATGTACTTATTGTGACGACGCATACTACAACAATGTTGACTACGCTCTTCATTCAATAGAACATAGTAAGGATGAGAGATATTCCTGTCACTTGTGTGATTATACAAATACGTCTAAATATCGCACGGAAGCACACGTTAGAGCTCACGAAGGTTCCACAAAGTACAAATGCGAGATTTGCAACAAACCCTTTAACATTAGCACCCACGCTAGAGAACATAAATATTTCCATACCGGCGAAAAACCTTTCCAGTGCGAAATTTGCGGAAAGCACTTTATGTTCTCTAGGATTTTGACAAAACATCGTCGTACCGCCCATTATGAAATAATGTTCGGTAAACCCTTAGCGAAATATGACTGTAAAGTTTGCAATAAACACTACGAATCTCTACCAGGACTTCAAAGGCACATGTACAGCAATCACAACGATACTGGTGAGGATTGGTCAGTTATATGTGATATTTGCGGAAAGAAAATCGCCACAAAAGAGaaattaaaatatcatttaaggacACATACCGGTGATAAACCGTTCCCTTGCCCGGCCTGTCCGAAGAGGTTTCCGAAAAAGGATCAACTCAAAGAACACGAGCGGGTACATACTGGAGAGAAACCGTTTGTTTGTATGTTTTGTGGAAAAGATTTTGGTCACAGAGCACCTTACAGATATCACATAAAGACTCACACTGGGGAACGGCCTTACACATGCCCAatttgtgggaaaggttttatttCGAAATCAGCTAAAGAAGGACATGCGAACGGCTGCTTTAAAAAATGA
Protein Sequence
MVCTDKYSHNHHMLKMSKLFTTFYFILIFVTFDTRFAFRKKTRRKRREPSEKIKRPRKPRRNKEKPKKQVVEPIKLEVPLRCTYCDDAYYNNVDYALHSIEHSKDERYSCHLCDYTNTSKYRTEAHVRAHEGSTKYKCEICNKPFNISTHAREHKYFHTGEKPFQCEICGKHFMFSRILTKHRRTAHYEIMFGKPLAKYDCKVCNKHYESLPGLQRHMYSNHNDTGEDWSVICDICGKKIATKEKLKYHLRTHTGDKPFPCPACPKRFPKKDQLKEHERVHTGEKPFVCMFCGKDFGHRAPYRYHIKTHTGERPYTCPICGKGFISKSAKEGHANGCFKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2