Basic Information

Gene Symbol
-
Assembly
GCA_944452705.1
Location
CALYCB010001087.1:504080-510772[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.0023 0.33 12.8 5.1 1 23 155 178 155 178 0.96
2 17 0.00032 0.044 15.5 0.9 1 23 187 210 187 210 0.96
3 17 0.00095 0.13 14.0 1.4 2 23 222 244 221 244 0.97
4 17 0.00064 0.089 14.5 0.1 1 23 253 276 253 276 0.97
5 17 0.0002 0.028 16.1 1.0 1 23 288 311 288 311 0.97
6 17 4.1e-05 0.0057 18.3 0.4 2 23 341 363 340 363 0.96
7 17 0.00057 0.081 14.7 1.2 2 23 373 395 372 395 0.96
8 17 0.005 0.7 11.7 0.4 2 19 400 417 399 420 0.92
9 17 0.00053 0.074 14.8 0.5 2 21 425 444 425 447 0.95
10 17 0.00021 0.029 16.1 2.2 2 23 456 478 455 478 0.96
11 17 0.0013 0.18 13.6 1.3 1 23 483 506 483 506 0.96
12 17 0.13 18 7.3 1.4 2 23 517 539 516 539 0.91
13 17 0.0024 0.34 12.7 1.0 1 23 560 583 560 583 0.94
14 17 0.014 2 10.3 0.3 2 23 590 610 589 610 0.96
15 17 0.0026 0.36 12.6 1.8 2 23 616 637 615 637 0.97
16 17 0.0058 0.81 11.5 0.2 1 23 703 725 703 725 0.97
17 17 0.074 10 8.1 1.9 1 23 731 754 731 754 0.97

Sequence Information

Coding Sequence
ATGCCCAAACTTAAATTGGAGCATGAGATCAAAAAAGAATCTTATGAAAATATTCAAATCAAAGAGGAGCGAAAAGATCCTACATCATTCTTGCCTGAAGAAGAAATGTGTTATGAGATAAAGCCTAAGAAGAAGAAGAAAAAAAAGAAAAAGCATCTTGAAGATCCATTTAAGGATATTAAGGAAAAAGTTCTTACACCGGTGACTATAATTACGGAAGCTTTGGAACCAGAAGTCAATATAAAAGTAGAAGATATTGAGGTGGCGCTAGATTTTAATGATTTTATAGACAATGATGATGTAAACATGTACGATGGGCAGATCAAGGAAGAGACACAGGATCCAGATGTCAACGCACAACCACCTAATCATGAAGCCGTAATACTTACTTTTGAACAAGTTGTCAATGAGAACAAACAAGACATAGAAGATATTAAAATTAATAAAAACAACTCACTGAAACACATTTGTAAAATATGCCATCTAGTATTTAAAACGGATAAAACGTTACTTATGCACCAAAGAAGAAAGCATAAAGCGTTCAGGAAATCCTTCGAACATATCTGCGATTCTTGTGGAATGTCCTATGAGACAAAGAATAGCTTAGTCGCTCACATCAAAAGAAAACACAGCGATGGCTGTCAGGAAGATGGCTTAGAAAAAACTTGTGAAATTTGTTTCCTAGTCTTCAAGGGGAAAGCTAGATTAAGAATGCACATGCGACGAAAACACGGAGCTTTTGAAGAAGCTTTCAAGTATATTTGTCCTGATTGCGGACTCGCCTATGATAAATATAGAAGCCTAATTATACACGTACAAAGAAAACATTCTAAAACAGAGGAACCAGTGCCAGATGTAATGTACAACTGCCCTTTTTGCAACAAAGTTTTTGGAAAACGCGAAACTTATGCGCGGCATGTACAACGAAATCATGAAGTGGATGATGATGGCAATGTAAAACCTAAAACTGTGATTAAAGAAATAGCTGAGAATTGTGAAAATACTGAAACAGGTGATATCATGTGTAAAGAATGTCCTTTAGTGTTTTCTTCTTTAGGATTTCTTAAATTGCATATGAGACGAAAGCACAACGCGTTAAAAGAGAATTTTAAGTTAAAATGCAGTATTTGCAGCTTGTCTTTTGAAAAAGTTGAAAGTCTTAAACGTCATGTTAAAAGAAAACACGATAAAGATACTTATTGTGATGTTTGTAATAAGAGCTTTGAGTCTCGAGAACAGATGTTGGCACATAGTCATATGCGAGCTATCCGTGAATGTTCACTATGCGGTCTTATATTCGCCACGCAAGGAGGGCTCTCAAAACATATGAGATGTATTCACAAAAAAGACCTCCCCAAGTCAATTATGTGTCACATGTGCAGTGAAAGTTTTTTCGATAAACGTCAATTAAAAGTGCATTTACAGAAAGACCATTTTAATATTTGGTACGAGTGCCGTAGTTGTAGTAAACGGTTTGTAGGAAAAGAAGGATATAGGAGACATATGCTGCTGAAACACCCAAAAGTTGGGACATCAAATCAGGAGCAGAAGTGTGAACACTGTTCAGAAACATTCTTGGATGAGGTGCAACTTTGTAACCATGTTGCTCTAGCTCATGCCGTTGAAAAACCAAACGAAGTTGTAATTAAAAAAGAAGAAATCGAATCAAAAGACCACTACCAATGCACAAAATGTCCAGTTCAATGTGTCACTTGGGAAGAGTTGCGCCTACATTACGAACAAAATCATAGAATGTTTGAGGAAACGCAATGTCAGACATGCGGCGAATTAGTCCGGCAACCTGATTTAGAAAAACACATGAAAAGCCACCAACAAGTGACACTTAAGTGTAAATATTGTGAATATAAATCGACAAGCAAAGTGAGTATGACTCAACATATATTAAGGCACAAGAACGCTACGACTATTCATTGTAGTTTTAGTGGTTGTAGGTATAAGACTTATTATGATGATGCTATGCAAAAACACAGCAAAAAGCATTATGACCAGGGTGTTAAATTACAATGCACAAAGTGTCCGTTTCAATCGATGAATAAATATATTCTGAAGTACCATGAGGAAGCTCATGTGACGGGTAAAAAACGATATCAGTGTGATCAATGCGATTATGCAACAATACTGCCCGCTAATCTAGTTCAGCACAAATATAAACACTCGAGTGAAAAGAAATTTAAATGTGAAGTTTGTCCGTTTGCAACGAAGTACAATACGTCTTTACGTTTTCATGTGAGAAAGAAACATTGTGATCTCCCAAATTAA
Protein Sequence
MPKLKLEHEIKKESYENIQIKEERKDPTSFLPEEEMCYEIKPKKKKKKKKKHLEDPFKDIKEKVLTPVTIITEALEPEVNIKVEDIEVALDFNDFIDNDDVNMYDGQIKEETQDPDVNAQPPNHEAVILTFEQVVNENKQDIEDIKINKNNSLKHICKICHLVFKTDKTLLMHQRRKHKAFRKSFEHICDSCGMSYETKNSLVAHIKRKHSDGCQEDGLEKTCEICFLVFKGKARLRMHMRRKHGAFEEAFKYICPDCGLAYDKYRSLIIHVQRKHSKTEEPVPDVMYNCPFCNKVFGKRETYARHVQRNHEVDDDGNVKPKTVIKEIAENCENTETGDIMCKECPLVFSSLGFLKLHMRRKHNALKENFKLKCSICSLSFEKVESLKRHVKRKHDKDTYCDVCNKSFESREQMLAHSHMRAIRECSLCGLIFATQGGLSKHMRCIHKKDLPKSIMCHMCSESFFDKRQLKVHLQKDHFNIWYECRSCSKRFVGKEGYRRHMLLKHPKVGTSNQEQKCEHCSETFLDEVQLCNHVALAHAVEKPNEVVIKKEEIESKDHYQCTKCPVQCVTWEELRLHYEQNHRMFEETQCQTCGELVRQPDLEKHMKSHQQVTLKCKYCEYKSTSKVSMTQHILRHKNATTIHCSFSGCRYKTYYDDAMQKHSKKHYDQGVKLQCTKCPFQSMNKYILKYHEEAHVTGKKRYQCDQCDYATILPANLVQHKYKHSSEKKFKCEVCPFATKYNTSLRFHVRKKHCDLPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-