Basic Information

Insect: Stenodema calcarata
Gene Symbol: Zeb1
Assembly: GCA_963920205.1
Location: OY986055.1:13015336-13024466[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00057 0.095 14.4 0.0 3 23 275 295 274 295 0.97

2 8 0.00022 0.036 15.7 0.3 1 23 301 323 301 323 0.98

3 8 0.0013 0.22 13.3 4.1 1 23 328 350 328 351 0.95

4 8 0.00042 0.07 14.8 1.0 1 23 357 380 357 380 0.97

5 8 0.01 1.7 10.5 2.4 1 23 395 417 395 417 0.98

6 8 0.00026 0.044 15.5 0.2 1 23 423 445 423 445 0.98

7 8 0.00017 0.029 16.1 2.0 2 23 451 472 450 472 0.97

8 8 0.00034 0.056 15.1 0.1 1 23 478 501 478 501 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00057	0.095	14.4	0.0	3	23	275	295	274	295	0.97
2	8	0.00022	0.036	15.7	0.3	1	23	301	323	301	323	0.98
3	8	0.0013	0.22	13.3	4.1	1	23	328	350	328	351	0.95
4	8	0.00042	0.07	14.8	1.0	1	23	357	380	357	380	0.97
5	8	0.01	1.7	10.5	2.4	1	23	395	417	395	417	0.98
6	8	0.00026	0.044	15.5	0.2	1	23	423	445	423	445	0.98
7	8	0.00017	0.029	16.1	2.0	2	23	451	472	450	472	0.97
8	8	0.00034	0.056	15.1	0.1	1	23	478	501	478	501	0.97

Sequence Information

Coding Sequence: ATGGCTGGTGAATGTGACATTACGGTGCTCCCGCCACCGCTGTTCAATTATGATGCAGATGACCTACTGGCCGAGTGGAAGCAATGGTTTCAGAAACTGGAGGAGTACCTCATAGCTTATGATCGAGCTGATTCTCCTGATGAGGACAAAATCAGAGTTTTGCTCAATCACCTCGGGAATGAAGGTAAGGAGATCTACGAATCTCTGGAGGGCAAAGAAAGTCCTGGAGAGAGGATAAAATCATTCAAAGAACTTACTGAAGCAATAACAACGTACTTTGATTCGGCCAGAAACGTCCTTTttggacgattcaaatttttcaaactcaaaagGAAACCCGAACAGTCTATTGGTGATTTTGTCAATGAGTTGACAAAAGCTGCCGATTGTTGTGAATTCGTCGAAAAGGACAACCTCATTAGAGACAAGCTTATAGAGCAACTCAAGGATAGATCCCTGATCGAGCGCCTTTTGGTTGAAGGTGGAACTTTAACGCTGGGAAGGGCTGTAAAAATCTGCCAGAAGTGGGAGAATCGAAAGTCCCAGACGAATGAAAATAAACCTCCTGGAAACGGCCCTAAATCACCTCAATCAGCAGCTAACATTCTCAGCCGAAGAAAGCGTGATTCCAATCCAAGAAAATTTCATCCTGATGACTTACCAGTTATCACGATTTTGGGTGTTGTTCCCCAACAAGATTTGAACACCGCTTCTAACGAAGCTGCAGCGTCCAGTGATGATCGTGATTTATGGGACGATGGTGATTCCGAACCAACTAATGAAGAGGAGTCCAGACCTGCCAGAGGGCCTCGGGGTGCTATGTGTGAGATTTGCGGCAGAATATTGAAGGGTCCAGCTGCGTTGAGGTACCACATGGAAACACACAGCGGCAAGAAGCCATATGCCTGTACAAAATGTGATTATCGTGGAGCCTTGAAAGCCTCATTGCAGTCCCATATGAGGATGCATGGAGgttATAAATTCAATTGCGATCAGTGTGATTTTAAAGCTCGTCGGTCGTATAATTTGAAGATGCACAAGAGAATACATCACACTGGTGAGAGGCCCTTCGTCTGTGAAATATGTGAAAGGAAATTTATCGATCGTGgatctttcaactttcatatGAGATCTCGCCATTTGGATCCCGCTAATGAGGCGCAGAAGGCAGGTGAGAAGACGTATTCCTGCGCACACTGTGATTACAAAACTGCGATGAAATCTGATTACAAGGATCATTCACTGACACATTCAGGTACTCGCCCCTTCGTGTGTGATGTTTGCGGATTCAGTGCAGCCTCCCGTGCGACGCTGAGGAGTCACAAGAGAATGCACAGCGAAAAAAACATGTCGTGTGAGTTTTGTGATTACAAGACGTCTAGGAAACAGTCGCTGACTGGACATATGAGACGGCACACTGGCGTCAGGCCTTACGAGTGTTCTTTCTGCGGATATAAAGCTGCCCAACGTGGGACGTTGACCAAACATATTGAAGTCATCCACAATAAGGTACCGAGCAGAAAATCAAAAGCCACCCCCAAACCACCTTCGGTCGCCAAACCGGCTGAAGTTCCGCCCGTACCGACCAGTCAGAACAGTTCAGAACAATCGTATCAACCTTCCAACGATTCGGGTATGAGGCTGAATTACAGCGAGCACCACCTCAGTCACCACAACTTCCACAATCCTCACACGATGCAGGCACCTCAAAATGTTTATATGGCCCAGAACAGTTACTGTCCCTCTTCGTATTACAACAGTGGTACAAACGTTGAAATAGGCCATAATAATTCACCTTTCGACTTTGACCAATTCGTCCGATGTAACATGATCAATTGA
Protein Sequence: MAGECDITVLPPPLFNYDADDLLAEWKQWFQKLEEYLIAYDRADSPDEDKIRVLLNHLGNEGKEIYESLEGKESPGERIKSFKELTEAITTYFDSARNVLFGRFKFFKLKRKPEQSIGDFVNELTKAADCCEFVEKDNLIRDKLIEQLKDRSLIERLLVEGGTLTLGRAVKICQKWENRKSQTNENKPPGNGPKSPQSAANILSRRKRDSNPRKFHPDDLPVITILGVVPQQDLNTASNEAAASSDDRDLWDDGDSEPTNEEESRPARGPRGAMCEICGRILKGPAALRYHMETHSGKKPYACTKCDYRGALKASLQSHMRMHGGYKFNCDQCDFKARRSYNLKMHKRIHHTGERPFVCEICERKFIDRGSFNFHMRSRHLDPANEAQKAGEKTYSCAHCDYKTAMKSDYKDHSLTHSGTRPFVCDVCGFSAASRATLRSHKRMHSEKNMSCEFCDYKTSRKQSLTGHMRRHTGVRPYECSFCGYKAAQRGTLTKHIEVIHNKVPSRKSKATPKPPSVAKPAEVPPVPTSQNSSEQSYQPSNDSGMRLNYSEHHLSHHNFHNPHTMQAPQNVYMAQNSYCPSSYYNSGTNVEIGHNNSPFDFDQFVRCNMIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -