Basic Information

Insect: Stegana nigrithorax
Gene Symbol: topi_1
Assembly: GCA_037044495.1
Location: JBAMBQ010003155.1:37281-39811[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 3.1e-05 0.0025 18.3 1.1 2 23 236 257 236 257 0.97

2 10 0.0084 0.68 10.6 0.0 2 23 285 306 284 306 0.96

3 10 0.00017 0.014 16.0 0.2 2 23 370 391 369 391 0.96

4 10 1.4 1.1e+02 3.6 0.9 1 21 438 458 438 462 0.88

5 10 0.26 21 6.0 0.1 2 15 477 490 476 499 0.79

6 10 4.4e-07 3.6e-05 24.1 1.9 1 23 523 545 523 545 0.95

7 10 0.00026 0.021 15.4 0.8 1 23 551 576 551 576 0.96

8 10 0.39 31 5.4 1.7 1 23 582 604 582 604 0.88

9 10 3.3e-08 2.7e-06 27.6 0.4 1 23 610 632 610 632 0.99

10 10 0.0015 0.12 13.0 2.0 1 23 638 661 638 661 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	3.1e-05	0.0025	18.3	1.1	2	23	236	257	236	257	0.97
2	10	0.0084	0.68	10.6	0.0	2	23	285	306	284	306	0.96
3	10	0.00017	0.014	16.0	0.2	2	23	370	391	369	391	0.96
4	10	1.4	1.1e+02	3.6	0.9	1	21	438	458	438	462	0.88
5	10	0.26	21	6.0	0.1	2	15	477	490	476	499	0.79
6	10	4.4e-07	3.6e-05	24.1	1.9	1	23	523	545	523	545	0.95
7	10	0.00026	0.021	15.4	0.8	1	23	551	576	551	576	0.96
8	10	0.39	31	5.4	1.7	1	23	582	604	582	604	0.88
9	10	3.3e-08	2.7e-06	27.6	0.4	1	23	610	632	610	632	0.99
10	10	0.0015	0.12	13.0	2.0	1	23	638	661	638	661	0.96

Sequence Information

Coding Sequence: ATGGAGAAGCAGGCTAATGATTTGAATGAAGCAGAGCTTCCTGTTGATTTCGGTAAGGAAACCAAAGAAGGGACATCAACTTCTTTGATTGCTGTGGCAGCTTCATCCATGTCTTACGATGCAGAACTcccaaatttattgttttcgagTGAAAATGAAGGAAATACCGAAAGTCTCAAGTCTGCACTCCGTAAAAGTTTATCAATCGCGTccaagaaaattgcaaaagaaaaccgATTCGCAGATCCcattttgcaacaaattttactCGATGAAGCCGAAAACCAAGTAAATTTTGATGCCGAAGCTGAAGGACtcaaattgaaacaatttcTAGAAGGAAATTTTGGagtaaaaaacagcaaatgtgCCGaAGCCGTGCCGCATATTAAAATAGCAACTGAGCTACCTTCAACGGCTTACCGCATAATTCGATGTTTTAATTGCGGGACACTTTTCGACATAATAAGCTTTCAGAACCACACTTGTGAATACGATGCTTCTCACACTCTGATCGATTTACCCGTTCCGATTGATAGAAAAGGACCTTCAGTGTACATGCCACCCCCGCCGAAGAAGCATGGCAGTGAACGAGTTATCATGGAGAACCAGATTCGAATTCGCCGTCACTTAAAGGATGAACTCAAGTATGACCTCAATCTAAACTTTGAGACTGTTACTGAAAAGAAGGGCAAGGGTCCAAATGAATGCACCATGTGCGAGCGTAAGTTTGTGCATGCCTCTGGGCTAGTGCGGCATATGGAAAAACATGCTCTGGACTTAATACCCACGAACATGCATACCAACCAAACCGGGGGGTGTCAAATGATGCATGGACTGCGTCTTGTACTGAAATGCGGCGACTGTGGACGCATCTTCTACGATATAGGCCTGGCACAAGAACATGTTGAGACGCATCTCGCAGTACGTACGGAGTTCAAAAGCGTTAACACTGACACTAGCACAAATTTTAAGGAATTCATGGCTGAGGCAGAGCTTACATTAGAGGAAGTCGGTGAGTACCGTTTTAACCATGTGTCAGCTGCAAGCATACAAGAGGAAAAGTCAAATGAAGTATTGAAAATGACTATATTAAGTGGTGTTCTCCAGTGCGAGTATTGTGAGTATGTGTTCTCAGATGTTTCATACCTTTTCGTTCATTCTGCCACGCATTCCCCGGAGCGGCCATTTGAATGTGCTGCATGTGATATTCAGATGAGCACACTGAAAGAATCACTGAATCATTATCAGACAGAATGCGGCTACATGagagaaaatttaaaacagcTTCAAATAACCGTGCAACGCTATTATGTATGCAATGTTTGCGAGAGCAAGTTCCTCACCCTAGAACAGCTTTATGAACATCGCTACTCTACTTATCACTATTTTCCACGTGAGGACAAAAACCAGCGTAGGCTTGTAATGCCCTGTGAGTACTGTGATGTGGTATTCACGTCTGCTCAAGATGCACCCAATCATTACGAGCAGAAGCatgtaagcaaaaagaaacgcGAGAAAGAGGTTCGCAGCACGAACCTTACCGCTTCTGGAAGAATTCGACAATATCTTTGCGATATTTGCGGTAAATCTTATACTCAGTCAAGTCATTTATGGCAGCATTTACGCTTTCATCAAGGCGTGAAACCCTTTGTGTGTCAGGAGGATGGTTGTGGCCGTAAATTCACGATTCGGCCTGATTTAAACGATCATATACGCAAGTGCCACACGGGAGAGCGTCCATACCATTGCCTGGTTTGCGGGAAGCGATTTTTAACGGGTTCAGTTTTTTATCAACACCGTCTTATACACCGAGGAGAACGCCGTTATGAATGTGAGGAATGTGGAAAGAGATTCTATCGTGCAGATGCCTTAAAGAATCACCAACGCATACATACGGGCGAAAAGCCGTACAGCTGCCTTTTCTGCACAAAAACTTTCAGGCAACGTGGCGACCGTGACAAACACATTCGAGCGCGTCATGCTCATTTAGACGCCAATTCAAGATTAAtgatgcaaatgcaaaagtttcagttagaagcagccgcagctgcagctgccttaaaagctaaaaaaatgcaagaaagCGGTGATAATCTTGTGGAGCCTGATACAGACATAGTTGCTGAAATGTTTCCTCAAAGTAGCACCGCAGTAACTATGTCATTATCGGAATATGGCATACCAGTTTCAGTGGAAACTCAAAAACTCCTTGAAGCAACCAATCTGACAGTTAATAAGTCCCCTTTGACAGCTGAGCAAATAGGCGGAAATGTCACATTTACATCGATAGGAAACAGAAACATTTCTATGGTTGATGATGACAAACTCCTTCAAAATGTACTCAACTCATAA
Protein Sequence: MEKQANDLNEAELPVDFGKETKEGTSTSLIAVAASSMSYDAELPNLLFSSENEGNTESLKSALRKSLSIASKKIAKENRFADPILQQILLDEAENQVNFDAEAEGLKLKQFLEGNFGVKNSKCAEAVPHIKIATELPSTAYRIIRCFNCGTLFDIISFQNHTCEYDASHTLIDLPVPIDRKGPSVYMPPPPKKHGSERVIMENQIRIRRHLKDELKYDLNLNFETVTEKKGKGPNECTMCERKFVHASGLVRHMEKHALDLIPTNMHTNQTGGCQMMHGLRLVLKCGDCGRIFYDIGLAQEHVETHLAVRTEFKSVNTDTSTNFKEFMAEAELTLEEVGEYRFNHVSAASIQEEKSNEVLKMTILSGVLQCEYCEYVFSDVSYLFVHSATHSPERPFECAACDIQMSTLKESLNHYQTECGYMRENLKQLQITVQRYYVCNVCESKFLTLEQLYEHRYSTYHYFPREDKNQRRLVMPCEYCDVVFTSAQDAPNHYEQKHVSKKKREKEVRSTNLTASGRIRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEDGCGRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDRDKHIRARHAHLDANSRLMMQMQKFQLEAAAAAAALKAKKMQESGDNLVEPDTDIVAEMFPQSSTAVTMSLSEYGIPVSVETQKLLEATNLTVNKSPLTAEQIGGNVTFTSIGNRNISMVDDDKLLQNVLNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -