Basic Information

Insect: Spilosoma lubricipeda
Gene Symbol: ZNF280A
Assembly: GCA_905220595.1
Location: HG992301.1:5991101-6000110[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00084 0.082 14.4 0.3 3 23 228 249 226 249 0.91

2 10 0.15 15 7.3 3.4 2 23 275 297 274 297 0.94

3 10 0.0062 0.61 11.6 0.8 1 23 320 342 320 342 0.97

4 10 0.00053 0.052 15.0 2.4 1 23 346 368 346 368 0.98

5 10 0.092 9 7.9 1.4 1 13 373 385 373 386 0.91

6 10 8.3e-05 0.0081 17.5 1.1 3 23 406 427 404 427 0.92

7 10 4.2e-07 4.1e-05 24.7 1.4 1 23 434 457 434 457 0.98

8 10 0.011 1.1 10.8 0.4 1 23 463 485 463 485 0.96

9 10 6.2e-07 6.1e-05 24.2 1.3 1 23 491 513 491 513 0.99

10 10 6.6e-05 0.0065 17.8 1.5 1 23 519 542 519 542 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00084	0.082	14.4	0.3	3	23	228	249	226	249	0.91
2	10	0.15	15	7.3	3.4	2	23	275	297	274	297	0.94
3	10	0.0062	0.61	11.6	0.8	1	23	320	342	320	342	0.97
4	10	0.00053	0.052	15.0	2.4	1	23	346	368	346	368	0.98
5	10	0.092	9	7.9	1.4	1	13	373	385	373	386	0.91
6	10	8.3e-05	0.0081	17.5	1.1	3	23	406	427	404	427	0.92
7	10	4.2e-07	4.1e-05	24.7	1.4	1	23	434	457	434	457	0.98
8	10	0.011	1.1	10.8	0.4	1	23	463	485	463	485	0.96
9	10	6.2e-07	6.1e-05	24.2	1.3	1	23	491	513	491	513	0.99
10	10	6.6e-05	0.0065	17.8	1.5	1	23	519	542	519	542	0.97

Sequence Information

Coding Sequence: ATGTTTAGTGGAACTTCATGCCGTTGTTGCCTTGTGCGACCTCCAGACAAGGATTTGTACTCCACCTACTCAAGACTTGGCAAACCTGAAGTTTATTCTGACATGTTGAAGGAATGCTTTGAAATAGATgTACCGGATGATTCTGGTGTTGATGATGCCGGTATATGTGAAATATGCATCATGCGTCTACGTGATGCTAGCGATTTCAAGCATCAAGTGCAGCGCTGTCAGATAGAGTTCAGAGCTAAACTGCTGAGTATGAAAGATGAAGCTCGATCAAAGGTGAAGCAAGAACTTGCTGAATTGGACGAGGAGAATGGGATATTATTCCTAGAAATCAAGGATGAAATGTCAGACTTTGAAGACGGAATCCTGAAAGAAGATGATGACGACAAGAACTTGGCTGAAATAATGGGCTTCAACAACGTCAGTGTAAAGAAGTATACCTCGAAGAAAGGCACTACTAAGCAAGGGTTAACCAAAACAGatcGTAAAAAGAAACACAGTTCTCTAAAGCTGTCACTACGCACGCTCACGACTATGAACGAAATACTTGACGCCCCGAAAATAATGCCATCTTGTTTGGTTACCGACAACACGAAACATAAATTCAACGTTGAGAATTTTCTCAAGAATTCCAACTGTACACCGTTTTCTAATAAAACGATATCAGGTATAATCTGCGCGTACTGCAAGGAGACTTACTCCGACCTCCAGCACCTTCGCTCTCACATCGCCGCCTCCCACTCCAAAGATCACCTGATAGACAGCAAACGCGTGGACAAAAGCAACCTCTCCATCAAAATGGACATCACAGACTTACAATGCAAGTTATGCCACACACCCTGTAACGTCATTTCCACCCTCAAAACCCACCTCATCAATAAACACGACATCAAATTCTATCCCGACGTCTACGATTACATCATAGAGTTCAAACTGACAGACGGACAAATATTTAACTGTGCACTATGTAATTCCACCTTCGAAACCTTCAAAATGCTACTCCAACACATGAATGGACATTACAGGAATTATATATGCGATATTTGCGATATGGGCTTCTTAAATAGACATAAATTGAGGAACCATCGGCGTACACACGATATAGGGACCTTTAATTGTTCGTTTTGTGATAAAGTCTTTAGTACACGAGTGAGAAAACTTTGCCATgagaaatatacacacaattCTAATGCTAGGTACACAACGAACTGCCCCCACTGTGATGAGTCGTTTACTAGTTATTATCAAAGAAACAGACACATGGCTGACGCTCATAATTCGGCCGCAGCATCATACAAATGCAATATTTGTGACAAATCTTTCATATTAAAATCGAAACTAACCTCTCATATAAAGAAAGTACACTTAATGGAACGGAATCACATCTGTGCGGAATGCGGTCAAGGATTTTTCATTAAACAATCTTTAGATGAACATATGATTAAGCATAATGGTGAAAGAATATATAAATGCACCGTTTGTAGTAAAGCTTATGCTAGGAAAAAGACCCTAAGAGAACATATGAGGATACATAATAATGATAGGAGGTTTAAATGTGGACTGTGCCCGCTTGCCTTCGTTCAGAAATGCAGTTTAAAGTCTCATATGTTGTCAAATCATGGGATTACTCTTGCTGAGTATGAGAGTAGCAGAACTGTGGCTTCGACTCCGTGA
Protein Sequence: MFSGTSCRCCLVRPPDKDLYSTYSRLGKPEVYSDMLKECFEIDVPDDSGVDDAGICEICIMRLRDASDFKHQVQRCQIEFRAKLLSMKDEARSKVKQELAELDEENGILFLEIKDEMSDFEDGILKEDDDDKNLAEIMGFNNVSVKKYTSKKGTTKQGLTKTDRKKKHSSLKLSLRTLTTMNEILDAPKIMPSCLVTDNTKHKFNVENFLKNSNCTPFSNKTISGIICAYCKETYSDLQHLRSHIAASHSKDHLIDSKRVDKSNLSIKMDITDLQCKLCHTPCNVISTLKTHLINKHDIKFYPDVYDYIIEFKLTDGQIFNCALCNSTFETFKMLLQHMNGHYRNYICDICDMGFLNRHKLRNHRRTHDIGTFNCSFCDKVFSTRVRKLCHEKYTHNSNARYTTNCPHCDESFTSYYQRNRHMADAHNSAAASYKCNICDKSFILKSKLTSHIKKVHLMERNHICAECGQGFFIKQSLDEHMIKHNGERIYKCTVCSKAYARKKTLREHMRIHNNDRRFKCGLCPLAFVQKCSLKSHMLSNHGITLAEYESSRTVASTP*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01198070;
90% Identity: iTF_00441848;
80% Identity: -