Basic Information

Gene Symbol
-
Assembly
GCA_949699795.1
Location
OX453075.1:10563000-10580085[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.017 1.6 10.1 0.6 1 23 135 158 135 158 0.94
2 11 3.4 3.1e+02 2.9 0.0 1 20 235 254 235 256 0.87
3 11 0.0022 0.2 12.9 0.1 1 20 285 304 285 306 0.95
4 11 0.059 5.3 8.4 0.2 3 21 327 345 325 346 0.93
5 11 0.055 5 8.5 1.6 1 23 358 380 358 380 0.98
6 11 2.4e-07 2.2e-05 25.4 0.8 1 23 387 409 387 409 0.98
7 11 0.00086 0.079 14.2 0.2 1 23 415 437 415 437 0.98
8 11 0.0092 0.83 11.0 0.0 1 23 443 465 443 465 0.95
9 11 0.0092 0.83 11.0 0.0 1 23 489 511 489 511 0.95
10 11 0.0092 0.83 11.0 0.0 1 23 539 561 539 561 0.95
11 11 0.13 11 7.4 0.0 1 21 589 609 589 610 0.91

Sequence Information

Coding Sequence
ATGATGTTTGATCCGCCAGATTATCCATATAAAGAATTAACAGACACTTTACGAGAGCATTACGGCCCTGACGATATTCTATTTGAAACAGCAAGCGATTCAGTCTCCATGGACAAAGATCTCGTAGAAGTCACAGAACAAATAATATCGTCCGTTGAGAATGAACTGTCCTTCAGTTCCAATCTAATGGGCAGATGTTTTAGCATCGAAAACACCTCACTTCTCGATATTGGTCCTACTGACCAGATAACCGAACTCTCTGTAGTTCAATCTGATAACTTGTTTAACTACGAGTCTACTTTATTAGACGAGAACACAGTCAACCAATTCTTACTGCCGTTGCAAGTCCCGAGTGCAAATGATAagGAGTCGGAAAACAATGGGCCTGACTTATTAGCTTTACACTCGTGTGTCGTGTGTCATGAAATATTTACCACCGACGTCGACCTACTCGATCATACAATCTCCGTCCACGCCTCCGACGCGACGGAAGAAAATCATAGCGTTCTCGTTGCAAATATTGATGAGACTCTAAATGAAGATCCCAACAACGGAGGCGAGGCTTTTGAGTGCGAGTGGCTGGTGTGCTGCCTGTGCGAACGAGTTTTGTCGACAGCCTTAGAAACAGAACCCACTGAACAATTATGCTGCACTGATGGCAATGGTAAGGGCAGCGTCGCTTCTCGCAAGCTCCACAGCATGTTTGTATGTGACTCTTGCAACTACTTGTTCGCTGATGGAGAAgccatggacagacacaagaTCACGTGCTTCGGACAAGAACAAAATTATACTGAACAGTTGGCGGACCTAAACATACAGCCAGAAGAACCACAACAGACATACAAAACATATCCCTGTAACCGATGCAATTTGGAATTTGTATCACTAGATGATCTGAGAGCACATACAAGTGATTGCGCCAGGCCGGTGCGTCGACGCGCCTACACGAATAGTAATAGCAACAAAATGTGGAACTGTGGATCTTGTAACCAACTATTTTCTTCGGCCAGGGAGCTCTACCGCCACAAACGCGGAGAGGACCGCCCAGAGGGCGCCCCGGTTCTGGCGTACGAGTGCGAGGTGTGCGAGAAGGTACTGGGTAGCGTCTGTGcactacacacacacaagaagatGCACAAGATTAGCAAACCGGGGTACCCATGTCGGGTCTGCGGTCGCCGCTTCAACCAGTCGGGTCACCTGGCGATTCACATGCGCATGCACACCGGCGAGCGGCCCTACCCTTGCGACCTCTGCCCGAAAGCATTTAAAGTAAAGGTAGAGCGGGACGACCACAGACGGACGCACACCGGGGAGCGGCCGTTCGCGTGCGCCGCCTGTCCCAAGACGTTCACCGCGGCGGCGCGCTTGCGTGAACACGCGCGCATACACACCGACCAGAGCCCCGTCCATCAGGTGGAGCGCGACGACCACAGACGGACGAACACTGGGGAGCGGCCGTTCGCGTGCGCCGCCTGCCCCAAGACGTTCACCGCGGCGGCGCGCTTGCGTGAACACGCGCGCATACACACCGACCAGAGCCCAACATGTGAGCCCGTCCACCAGGTGGAGCGCGGCGACCACAGACGGACGCACACCGGGGAGCGGCTGTTCGCGTGCGCCGCCTGCCCCAAGACGTTCACCGCGGCGGCGCGCTTGCGTGAACACGCGCGCATACACACCGACCAGAGGTTACTATACGACCTCTTGCTAAGAGTGGAGCGCGACGACCACAGACGGACGCACACCGGGGAGCGGCCGTTCGCGTGCGCCGCCTGCCCCAAGACGTTCACCGCGGCGGCGCGCTTGCGTGAACACGCGCGCATATACACCGACCAGAGGTTACTATACGACCTGTACGTCGGAGCCATACACAAACCAAGTAACTTAGTTACTTAG
Protein Sequence
MMFDPPDYPYKELTDTLREHYGPDDILFETASDSVSMDKDLVEVTEQIISSVENELSFSSNLMGRCFSIENTSLLDIGPTDQITELSVVQSDNLFNYESTLLDENTVNQFLLPLQVPSANDKESENNGPDLLALHSCVVCHEIFTTDVDLLDHTISVHASDATEENHSVLVANIDETLNEDPNNGGEAFECEWLVCCLCERVLSTALETEPTEQLCCTDGNGKGSVASRKLHSMFVCDSCNYLFADGEAMDRHKITCFGQEQNYTEQLADLNIQPEEPQQTYKTYPCNRCNLEFVSLDDLRAHTSDCARPVRRRAYTNSNSNKMWNCGSCNQLFSSARELYRHKRGEDRPEGAPVLAYECEVCEKVLGSVCALHTHKKMHKISKPGYPCRVCGRRFNQSGHLAIHMRMHTGERPYPCDLCPKAFKVKVERDDHRRTHTGERPFACAACPKTFTAAARLREHARIHTDQSPVHQVERDDHRRTNTGERPFACAACPKTFTAAARLREHARIHTDQSPTCEPVHQVERGDHRRTHTGERLFACAACPKTFTAAARLREHARIHTDQRLLYDLLLRVERDDHRRTHTGERPFACAACPKTFTAAARLREHARIYTDQRLLYDLYVGAIHKPSNLVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01082715;
90% Identity
-
80% Identity
-