Ssim026812.1
Basic Information
- Insect
- Spicauda simplicius
- Gene Symbol
- -
- Assembly
- GCA_949699795.1
- Location
- OX453086.1:376977-378218[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00019 0.018 16.3 2.3 1 23 56 79 56 79 0.95 2 10 2.9e-05 0.0026 18.9 2.5 3 23 88 109 86 109 0.94 3 10 0.22 20 6.6 5.3 2 23 117 139 116 139 0.95 4 10 4.5e-05 0.0041 18.2 1.9 2 23 147 169 146 169 0.92 5 10 0.0027 0.25 12.7 7.7 1 23 176 199 176 199 0.93 6 10 0.0019 0.17 13.1 6.4 1 23 205 228 205 228 0.95 7 10 5.5e-05 0.005 18.0 0.3 2 23 236 257 235 257 0.97 8 10 0.001 0.094 14.0 2.2 2 23 265 287 264 287 0.96 9 10 8.3e-05 0.0076 17.4 3.4 2 23 294 316 293 316 0.94 10 10 9e-05 0.0082 17.3 1.7 3 23 328 348 326 348 0.98
Sequence Information
- Coding Sequence
- ATGGAGGAGCCCGCAGCGATGCCCCTGGAGGCGAAGACTGAAGACGTGAAGCCGGTGAAGTTCATCAGCGTGAACAACCCGGCCCTCACAGACGAGCAGAGGGCCATGTACGAGTCAGTCCTGTCTACCTGGAAACCTGTGCTATTCCCAAAGCGAACTAAGAGATACATTtgccaaaaatgcaataaagaattcAAGAACTACCAGAACTTGTACCTCCATACCACCAGAGTCCACTCTTCGGAGGAATCGGCGGTGATTTGTGATATATGTGATAAAACGTTCAAAAACAAGCACTATCTGTACATGCATCGGATGAACAAACACTACTCTGACTCAGAGAAGTGCTACTGCCAGTTCTGTCTCCAGGAGTTCAGGACGCGACGGGCCTTGCACATGCACGTGAAGAGAATCCATCCGAACACGCTTCCAGAGATAAAATGCCATGAGTGCGGCAAAGAGTTTAGTGTGCCGTACAAACTGAGGTACCACATCGATGCTTGCCATCGTCAGGACAAGGAGAAGTACAAATGCCACATCTGTGACAAATTGTACAAGAGTCATCTCAATCTGAACAGGCATCTTCACTTCCAACACTCGCAAGTGGAGAGACACACGTGCGTGTTTTGCCCGATGACCTTCAAATCGCGGCATCACATGAAGCGACATATCCTCAACATCCATCCTCCGCTGGAGTCGAAGGTCACCTGTCCGGAATGCTTGAAGGAGTTCAAGAACGACCAATACCTGAAAGAGCATATGCAAGTCCACTCCTCGCTGGACACGAAGGTCAAATGCGACTTGTGCGATAAATTCTTCCATTCAGCTGTTCGGTTGAAGAAACACAAGAAAATCGTACATCCGAACAAACCGAAGCTTAGATGCGAGAAGTGTGATAAGGAATTCGCGCACGCGCATTACTTGCGGAGACACAACAACTCCGTGCATGTGGAAATGGACGAAAGCCAGTACCAATTTGGGTGTGATCAGTGCGGGAAGAAATTCAAAATTAGACGCTATTTAAACAATCACTTGCAAAGACACGAGCAGCAACATCTGAAGAGAATATCGCAGATGGTCAAGACGGTGATGGGTGGTGACGGCGAGCCGAAGGAGAAGGTGGCCAAGAAGAAGGGCAGGCCGCGCAAAACGAGGAAAGAAATCGAGTTCATCAAATGCGAACCGGTTTCCAGCTCCGATTCCGAATCCGGGGAGACGGACGACGATTCCGATTCGGAATAA
- Protein Sequence
- MEEPAAMPLEAKTEDVKPVKFISVNNPALTDEQRAMYESVLSTWKPVLFPKRTKRYICQKCNKEFKNYQNLYLHTTRVHSSEESAVICDICDKTFKNKHYLYMHRMNKHYSDSEKCYCQFCLQEFRTRRALHMHVKRIHPNTLPEIKCHECGKEFSVPYKLRYHIDACHRQDKEKYKCHICDKLYKSHLNLNRHLHFQHSQVERHTCVFCPMTFKSRHHMKRHILNIHPPLESKVTCPECLKEFKNDQYLKEHMQVHSSLDTKVKCDLCDKFFHSAVRLKKHKKIVHPNKPKLRCEKCDKEFAHAHYLRRHNNSVHVEMDESQYQFGCDQCGKKFKIRRYLNNHLQRHEQQHLKRISQMVKTVMGGDGEPKEKVAKKKGRPRKTRKEIEFIKCEPVSSSDSESGETDDDSDSE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00943106;
- 90% Identity
- iTF_00288288;
- 80% Identity
- -