Ssim027096.1
Basic Information
- Insect
- Spicauda simplicius
- Gene Symbol
- ZEB2
- Assembly
- GCA_949699795.1
- Location
- OX453086.1:3517800-3524910[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.055 5 8.5 0.1 2 23 50 70 49 70 0.95 2 11 0.00065 0.059 14.6 0.9 1 21 76 96 76 101 0.94 3 11 0.00065 0.059 14.6 0.9 1 21 113 133 113 138 0.94 4 11 0.00065 0.059 14.6 0.9 1 21 150 170 150 175 0.94 5 11 0.00065 0.059 14.6 0.9 1 21 187 207 187 212 0.94 6 11 0.00065 0.059 14.6 0.9 1 21 224 244 224 249 0.94 7 11 0.082 7.5 8.0 0.4 1 17 261 277 261 278 0.90 8 11 2.4e-05 0.0022 19.1 1.1 1 23 294 317 294 317 0.96 9 11 0.0012 0.11 13.8 4.6 1 23 323 346 323 346 0.97 10 11 1.3e-05 0.0012 19.9 0.4 3 23 357 377 356 377 0.97 11 11 1.5e-05 0.0014 19.8 0.4 2 23 384 406 383 406 0.96
Sequence Information
- Coding Sequence
- ATGACAGGAACACACACCAGGTGGAGCCCTGTTGCCCTGCATCGCTATGTCGTCATCAGAACACCACCAATAATCAGCATTTATGCCGTCATCGGCGACCAATGGTGTAGCTGCATTCGgATCCACGCGGGCCCCCCAGCGCGTACCCCATGCGGCAAGTGCGGCAAGATGGTCCAAGTTGCTCTCCTCTCCACCCACTTGCGTCTCCACGAGCCGCGCGCGCAGTACTCGTGTACAGCGTGCAACAAGCGCTTCGTCTCGCGCGAGTCCTACCAAGTGCACCTCAAGTACACGCTCGTGCACGCGAAGGTGGACGTGCTCAATAGCCACGCGCAGTACTCTTGTACCGCGTGCAACAAGCGCTTCGTCTCGCGCGAGTCCTACCAGGTGCACCTCAAGTACACGCTCGTGCACGCGAAGGTGGACGTGCTCAATAGCCACGCGCAGTACTCTTGTACCGCGTGCAACAAGCGCTTCGTCTCGCGCGAGTCCTACCAGGTGCACCTCAAGTACACGCTCGTGCACGCGAAGGTGGACGTGCTCAATAGCCACGCGCAGTACTCTTGTACCGCGTGCAACAAGCGCTTCGTCTCGCGCGAGTCCTACCAGGTGCACCTCAAGTACACGCTCGTGCACGCGAAGGTGGACGTGCTCAATAGCCACGCGCAGTACTCTTGTACCGCGTGCAACAAGCGCTTCGTCTCGCGCGAGTCCTACCAGGTGCACCTCAAGTACACGCTCGTGCACGCGAAGGTGGACGTGCTCAATAGCCACGCGCAGTACTCTTGTACCGCGTGCAACAAGCGCTTCGTCTCGCGCGAGTCCTACCAGGTGCTCCTCAAGTACACGCTCGTGCACGCGAAGGTGGACGTGCTCAAGTTCAAATGCACGATGTGTGACAAAGGGTACCGCACTAAGATTGAACTAAGAGACCACGTGAACTACAGTCATATGGGGAAAACACAATATAAGTGTCACATTTGTGAAAAGccATTATCGAGTCATAAAAGCTACGTTAGACACGTGCGCTACACACACGAAGGGCTTAAAGAGAAAAAGGATAAAATATGCCAGCAGTGCGGAAAAGCCTTTAGTGGAAAGAAAAGTCTACGCGAGCACGAAAGGATACATACAGGGGAGCGCCCTCTATCTTGCGAAATATGCGGAGCGACCTTCAGACAAAGCGCGTCTCTGTTCACCCACAAGAAGAGAGTTCACAACGTGTACCCTGTGAAGAAGACCGTGCGAGTGGAAGAAAGCGATAAAACGAGCTAA
- Protein Sequence
- MTGTHTRWSPVALHRYVVIRTPPIISIYAVIGDQWCSCIRIHAGPPARTPCGKCGKMVQVALLSTHLRLHEPRAQYSCTACNKRFVSRESYQVHLKYTLVHAKVDVLNSHAQYSCTACNKRFVSRESYQVHLKYTLVHAKVDVLNSHAQYSCTACNKRFVSRESYQVHLKYTLVHAKVDVLNSHAQYSCTACNKRFVSRESYQVHLKYTLVHAKVDVLNSHAQYSCTACNKRFVSRESYQVHLKYTLVHAKVDVLNSHAQYSCTACNKRFVSRESYQVLLKYTLVHAKVDVLKFKCTMCDKGYRTKIELRDHVNYSHMGKTQYKCHICEKPLSSHKSYVRHVRYTHEGLKEKKDKICQQCGKAFSGKKSLREHERIHTGERPLSCEICGATFRQSASLFTHKKRVHNVYPVKKTVRVEESDKTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -