Spin004431.1
Basic Information
- Insect
- Sphinx pinastri
- Gene Symbol
- -
- Assembly
- GCA_947568825.1
- Location
- OX387641.1:7491794-7510433[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.21 17 6.7 0.2 1 23 200 223 200 223 0.94 2 12 0.019 1.6 10.0 2.0 1 23 231 253 231 253 0.96 3 12 0.0011 0.091 13.9 1.8 1 23 257 279 257 279 0.99 4 12 0.0031 0.26 12.5 5.5 1 23 286 309 286 309 0.96 5 12 0.0042 0.34 12.1 1.0 2 21 314 333 314 334 0.92 6 12 0.00023 0.019 16.0 0.9 2 23 350 371 349 371 0.94 7 12 0.00063 0.051 14.7 0.3 1 23 376 398 376 398 0.98 8 12 0.00013 0.01 16.8 3.7 1 21 407 427 407 432 0.94 9 12 0.00034 0.028 15.5 1.7 1 23 440 463 440 463 0.92 10 12 0.016 1.3 10.3 0.2 1 23 469 492 469 492 0.88 11 12 0.015 1.3 10.3 0.4 3 19 505 521 503 522 0.89 12 12 0.028 2.3 9.4 0.6 1 23 535 558 535 558 0.95
Sequence Information
- Coding Sequence
- ATGATGGTGCCAGATGAGATTACAATTCAAGTATGCTGGGAGTGCTTGGCAGCTGTCAGGTCCGTGATGACATTCCAAGCGAGGATCCTGCAGTCCTTTGAGGTCCTGATAAAGTATTCTAATGAGCACACATTCCTGAACTCACCTGAAGATTTCACCGAGTATTCCTCAACAAGACTGACTTTGTCAAATGTGGAGGTGTACTCCACGCTGAAGGATGAAAAAGATGGATTCATGATTGAAGTGAAGGTAGAAGAGGAGCCGAAGTATGAGCCTAATGAAAATTCATCTGTAAAAGAAGAGGAAAAATACGCGCAAGACGATTTCTACGAAGACTTGCCGTCGCAGGAGGCGGACGCTTCCTCAGAAGACGATATAAAACTGTCCAAACTCAAGAGGAAGAAAGAGAAGAGAGTTAAGAAGAGTAAGAAAGACCGGAAGAAGAAGGAGAAGCACAAACCCGAACTACAGCTCAAAGCCAACAGGAAGCTGAAGAACCTGCCCGAGGACCTGGTGGAGCTGTACAGCATGAGCGAGGAAGAGATGTGGGCAGTGAGGGCTGCAGACGTGGCCAGCGCTGACTTCACTAACCTGCGGTACAAGTGTACTGACTGTATCCTGGGGTTCAATACTGAGAAGCTGATGGCTGATCATCTCAATGGGAAGCATCGAGAGAAAGGCGAAGACTGTCACCAGTGTAACATTTGCAAGGCATATTTCCTGACCAAAGACAATCTGTCTGTGCATCGATCTCTTCATCTAACAGCCTATAGGTGTAAACAGTGTGGAGCGAAGACCTCCCTCAAGCGTCTGATGATGAAACACATGAGCACGCATCGCCGGGATGCGGACGATTTCAAATGTGTCACGTGTGGGTGTGAGTTCAGCACAAAGTCCAAACTGGCGTACCACAGAAGCGTCTGCCATCAGGAGAAGCCCCAGTGCGACTGCTGCGGAAAAGTGTTTGCTAATAAGATGACTCTCAAGTATCATTTGAAAATTCTCCCTCAAAACAAAGACAACAAATCTAAAGAGAAGTTACATATACCGTGCAAAGGGTGTAATAAGGTGTTCCACTCGAAGAAGAGTTACCGAGCACACGTCGTGATCCACGACGGCCTCTCATACCCATGTCCGACTTGCGGCAAGTTGTTCCAATGGAAGCGGAATCTGGCGAGACACGCTCGCAACCACAGAGAGAGGGAGGCCGGGGCGCTACACGAGTGCAAGGACTGCGGCAAGACGTTCGCGAGTCGAGACTGTTACGCGAACCATCTGAGGCTGAGCAAGAAGCATGCCGGTGAGGAGAGCTTCGCACACGAGTGTAATTATTGCGGTAAGAAGTTCCCCACCAAATGGTGCATGGTGGATCATATAGACTGGGAACATCTGAAGCGGATCAAATACCAGTGCAGTGTGTGTTTCAAGCCATTCAAAACAGCCAAGATAATGGTGGCGCACGTGAATAACATCCACGAGGGCAGGAGGAGGGAGCAGGAGGGCGAGCACCTGTGTGAGATATGCGGGAAGTCTTATAAGACAGTGAAACGACTGAAGGGACATGTATGGGCGATGCATACGAAACGGTCTACAACCAAAAGCTACAAGTGCAAGTTGTGTCCAGCGACGTTTACTTGGCAGACGTCGATCTATAAGCACGTCAAGATTATGCACGACAACGGCAAGCGGAAGTCACAAGTCCGCCCGCCTCCAGTGAAGAAGGAAGACTACCCAGTACGTCTGGAATTGGCGAACATGCAGTACTTCGGACAAAACATCAACCTCATGCAGAATATAGTGCAGACTGTACATGTCCAACACGGTGGAGTGATGCAGAACCTCGTTTGA
- Protein Sequence
- MMVPDEITIQVCWECLAAVRSVMTFQARILQSFEVLIKYSNEHTFLNSPEDFTEYSSTRLTLSNVEVYSTLKDEKDGFMIEVKVEEEPKYEPNENSSVKEEEKYAQDDFYEDLPSQEADASSEDDIKLSKLKRKKEKRVKKSKKDRKKKEKHKPELQLKANRKLKNLPEDLVELYSMSEEEMWAVRAADVASADFTNLRYKCTDCILGFNTEKLMADHLNGKHREKGEDCHQCNICKAYFLTKDNLSVHRSLHLTAYRCKQCGAKTSLKRLMMKHMSTHRRDADDFKCVTCGCEFSTKSKLAYHRSVCHQEKPQCDCCGKVFANKMTLKYHLKILPQNKDNKSKEKLHIPCKGCNKVFHSKKSYRAHVVIHDGLSYPCPTCGKLFQWKRNLARHARNHREREAGALHECKDCGKTFASRDCYANHLRLSKKHAGEESFAHECNYCGKKFPTKWCMVDHIDWEHLKRIKYQCSVCFKPFKTAKIMVAHVNNIHEGRRREQEGEHLCEICGKSYKTVKRLKGHVWAMHTKRSTTKSYKCKLCPATFTWQTSIYKHVKIMHDNGKRKSQVRPPPVKKEDYPVRLELANMQYFGQNINLMQNIVQTVHVQHGGVMQNLV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00859770;
- 90% Identity
- iTF_00859770;
- 80% Identity
- -