Spin026114.1
Basic Information
- Insect
- Sphinx pinastri
- Gene Symbol
- -
- Assembly
- GCA_947568825.1
- Location
- OX387618.1:2933858-2949520[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 7.4 6e+02 1.8 0.4 2 11 253 262 253 274 0.81 2 11 9.6 7.8e+02 1.5 1.1 5 22 282 299 280 302 0.87 3 11 0.001 0.083 14.0 3.0 2 23 429 451 428 451 0.94 4 11 0.0002 0.016 16.2 0.1 1 23 457 479 457 479 0.97 5 11 0.015 1.2 10.3 0.1 1 23 491 514 491 514 0.88 6 11 1.7e-06 0.00014 22.8 3.7 1 23 519 541 519 541 0.98 7 11 2.3e-06 0.00019 22.3 1.0 1 23 547 569 547 569 0.98 8 11 0.00011 0.0086 17.1 4.9 1 23 575 597 575 597 0.98 9 11 1.3e-07 1.1e-05 26.2 0.3 1 23 603 625 603 625 0.98 10 11 0.017 1.4 10.2 2.7 1 23 631 653 631 653 0.96 11 11 0.013 1.1 10.5 1.7 2 23 684 706 683 706 0.94
Sequence Information
- Coding Sequence
- ATGGAAGTATTTCTATATAATTCAACAGTTTGCAGACTATGTGGAGAAGAAAATGATAATGGGTCGTTGTTATATTCGTGCGAAGATAATAATCAAAACCTAAGTGAAATTATTAATGCGTATTTGCCAATAAAGGTATCTGACGATGCTGAACTGCCTAGAACCATTTGCCCTGGATGTACCATACAATTGGAAGCCACCGTAGAGTTCTTGAATCTTATTATTAATGGTCAGAAAATAATTCGTGAGTTGCACCAGAGAGAAAAAGAGTACAAAAAGTCAGTTCTAAACTCATCAGTTACTGAGAAAATTGTTTATGAAGTAAACACAAGCGATGGAGTCTACCAAGTAGAACATCCCATTGCACTCCAAGTTGCTGGTCTAGAGAAGCCGAAGCGCAAACGCGGCCGTCCTCCGAAGAAACCCAAAACTCCTGAAGAGCTTGCGGAAGAGGCTGCCAAGCAGCAGGAGTGTTCGCAGACGAAACAATATGAGGAAAAGGATTTGGAGCCCACTGGCAAACGGAGAAGGAAAACTCCTACCCGATTTAAGGAAGCTGTACAGGGCAAGGAGCTCGAAAGGATATTTAAAGAAGAGGGTGTGATTGACGGTGATGAAGGAAAGTCGAAGAAAGATCCGGACAAGCTCAAGGAACCTGAAGTGATTGGACACTTGGAGGAGTCGGGCGAGCTCGTGGTTATTGGCAAGGGAAAGGGTCGCGGCAGACCTAAAGGCCGCACGCGTCCCAACCGCGAGCAGTGCGGCATCTGCGGCTTGCAGTTCTCATGCGTGGGGCGCTACATGTCGCACGTGGCGGCGCACGGGCCGGTGCTGTTCCGTTGCACGTGCGGCGCGGCGTGCGGCTCGCGGCTCGCGCTGCAACACCACCAGCGCGCCGCGCAACACCACGGACACGAGGTCATACCCTGCGAGATCGTGCAGGAGGACGCGGAACCGGAAAACGTGGAAGAACAGTTGCCCACAATAACTATAGAAGATCAGACTCCGCCTGAAACCGACACCGAGGTGTCCGTAGTTGACGATACACCTGTCATGGACTCTTTGTCCGATTTGAATCCTGAACCAAATAACGTGAGCGAAGAGCAGACCGTTGTGTTGTCAGAGACTGAGTCTAAAGATATACCCAAACAAGAAGTGCAAGAGGAATATATTGAAGATAATATGGACTCAAATGGCATTCCAGAGGAAACAATAGTGGAGGCAGTAGCCGAAGACAATGTGATACAAGAAGTCGAGACGACTCCCCAAGGCAAGGTGAAACTGAAATGCAACCACTGTGACAAGACTTACAGTTCCAAACAGAGCAAGTCCTTGCACATGAAGGCGGCGCACGAGGGCCTGCGCCCGTTCGTGTGCGGCGAGTGCGGCGCGCGGTTCTCGTACCCGCGCTCGCTGGCGCTGCACCGCATCTCGCACGCCAAGCACAAGCCACACACACCCGCCGCCGGGTACGCCTGCGACCTCTGCGGGAAGGTGCTGAGCCACCCGTCCTCTATAGTGTACCACAAGGAGGCGGAGCACGCGGGCCAGAAGTTCGTGTGCAACAAGTGTGGCAAGCAGTTCAAGCACAAGCAGCTGCTGCAGCGGCACCAGCTCGTACACACGCAACACCGACCTTACACCTGCAAGGTATGCAACGCGACGTTCAAGACCAAAGCGAATCTGATGAATCATCAGCTGCTGCACTCCGGCGTGAAGAGGTTCTCGTGCGAGATCTGCAAGCACAAGTTCGCGCACAAAACCAGTCTTACGCTGCATATGAGGTGGCATGCAGGCACGAAGCCGTTCGTGTGCAAGACATGCGGCAAGAGCTTCAGCCAGAAGGGCAACCTGGCGGAGCACGCGCGCATCCACTCCGGCGAGAAGCCCTTCGCCTGCCTCCTGTGTCCGCGGCGCTTCACCACCTCCTCGCAGCACCGCCTGCACGCGCGCCGCCACGCCGACCGCCACGCCGACCGCCACGCCGACCGCCACGCCGACCGCCACGCCGACCGCGACCGCAAGCAGCGCCGCCTGCCGCGCTGCACCCACTGCACCCACTGCGCCAGGGCCTTCCCCACCACTGCCGATCTCGCCAAGCATAATAGGTTAATCCACGGTCAAATCAGTCTCTTGACATCAGCAAACCCGCCCCAAATAATCGAAGAGCCGACAGTGTACGAGATACAAACCCAAGAAGAGAAACTGTCCATAGAAGAGGAACCAAGCGAGGACCTCGAGGAGAGAGTCATCTACGTCGCATATGATATGGACGAGGAAGACTCGCCAGCTATCCATATACTTAACTCGGAACAAGAGGAGTTGGAGGAGTTGGAACAGGCGCCGAAGTCAGTGTCGTCGTGTTCGCTGTTCGGCGGCGAGTCGCTGCTGGCGGCGCCACTGTCGCCCGACGTCACACGCGTCACACACGTCACACGCGTCACACACGTCACACGCGTCACACGCGTCACACACCCCGACGACCCGCCCGACCAGCTGCCCACGCAACCAGACCACATGCCAGTGACGGACGAGCAAGGCAATCCTCTGCACTTCACTATGCAAGATGGTACGCGGCTCGCTATAACGTCTGCTGATGGGAAATCGTTACAGGTGATAACGCAGGACGGACAAACTATACCTGTTGAGATTAACGGATTTGCCGAGGAGGAGGAGATGGACAACCCCGACACAATAGTTCACCAGCTCAACCTGCAGAAGACTGTAGACTCGAACGTCTCGCCCGTCACGCATTTTTTCACCATAGTCTAA
- Protein Sequence
- MEVFLYNSTVCRLCGEENDNGSLLYSCEDNNQNLSEIINAYLPIKVSDDAELPRTICPGCTIQLEATVEFLNLIINGQKIIRELHQREKEYKKSVLNSSVTEKIVYEVNTSDGVYQVEHPIALQVAGLEKPKRKRGRPPKKPKTPEELAEEAAKQQECSQTKQYEEKDLEPTGKRRRKTPTRFKEAVQGKELERIFKEEGVIDGDEGKSKKDPDKLKEPEVIGHLEESGELVVIGKGKGRGRPKGRTRPNREQCGICGLQFSCVGRYMSHVAAHGPVLFRCTCGAACGSRLALQHHQRAAQHHGHEVIPCEIVQEDAEPENVEEQLPTITIEDQTPPETDTEVSVVDDTPVMDSLSDLNPEPNNVSEEQTVVLSETESKDIPKQEVQEEYIEDNMDSNGIPEETIVEAVAEDNVIQEVETTPQGKVKLKCNHCDKTYSSKQSKSLHMKAAHEGLRPFVCGECGARFSYPRSLALHRISHAKHKPHTPAAGYACDLCGKVLSHPSSIVYHKEAEHAGQKFVCNKCGKQFKHKQLLQRHQLVHTQHRPYTCKVCNATFKTKANLMNHQLLHSGVKRFSCEICKHKFAHKTSLTLHMRWHAGTKPFVCKTCGKSFSQKGNLAEHARIHSGEKPFACLLCPRRFTTSSQHRLHARRHADRHADRHADRHADRHADRDRKQRRLPRCTHCTHCARAFPTTADLAKHNRLIHGQISLLTSANPPQIIEEPTVYEIQTQEEKLSIEEEPSEDLEERVIYVAYDMDEEDSPAIHILNSEQEELEELEQAPKSVSSCSLFGGESLLAAPLSPDVTRVTHVTRVTHVTRVTRVTHPDDPPDQLPTQPDHMPVTDEQGNPLHFTMQDGTRLAITSADGKSLQVITQDGQTIPVEINGFAEEEEMDNPDTIVHQLNLQKTVDSNVSPVTHFFTIV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00859763;
- 90% Identity
- iTF_00859763;
- 80% Identity
- -