Basic Information

Insect: Sphinx pinastri
Gene Symbol: ZNF280A
Assembly: GCA_947568825.1
Location: OX387616.1:4594468-4599674[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.037 3 9.1 0.3 2 23 237 259 236 259 0.95

2 10 0.014 1.1 10.5 0.5 2 23 285 307 284 307 0.95

3 10 0.016 1.3 10.3 0.5 2 23 331 352 330 352 0.95

4 10 1.4e-05 0.0012 19.8 1.7 1 23 356 378 356 378 0.98

5 10 0.08 6.5 8.0 1.5 1 13 383 395 383 396 0.91

6 10 0.00019 0.016 16.3 3.5 3 23 416 437 414 437 0.95

7 10 1.9e-07 1.6e-05 25.7 0.9 1 23 444 467 444 467 0.98

8 10 0.011 0.87 10.8 0.4 1 23 473 495 473 495 0.96

9 10 2.7e-07 2.2e-05 25.2 0.8 1 23 501 523 501 523 0.99

10 10 0.00018 0.015 16.3 1.3 1 23 529 552 529 552 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.037	3	9.1	0.3	2	23	237	259	236	259	0.95
2	10	0.014	1.1	10.5	0.5	2	23	285	307	284	307	0.95
3	10	0.016	1.3	10.3	0.5	2	23	331	352	330	352	0.95
4	10	1.4e-05	0.0012	19.8	1.7	1	23	356	378	356	378	0.98
5	10	0.08	6.5	8.0	1.5	1	13	383	395	383	396	0.91
6	10	0.00019	0.016	16.3	3.5	3	23	416	437	414	437	0.95
7	10	1.9e-07	1.6e-05	25.7	0.9	1	23	444	467	444	467	0.98
8	10	0.011	0.87	10.8	0.4	1	23	473	495	473	495	0.96
9	10	2.7e-07	2.2e-05	25.2	0.8	1	23	501	523	501	523	0.99
10	10	0.00018	0.015	16.3	1.3	1	23	529	552	529	552	0.97

Sequence Information

Coding Sequence: ATGTCAAGTGTTTCTATGTGCCGATGCTGCATGCTGCGCCCACCGGATAAGAAACTAAAAGCATCATATATATCTTTAGGGAAATCTGAAGTGTACGCTGATATGCTGAAGGACTGTTTTGAAATCCATATGGCAGTGGGCGATGTGGAGGGCGATGGGGGTATCTGTGAGGTGTGTATCATGCGGCTGCGCGACGCGTGCGACTTCAAGCAGCAAGTGCAGCGCTGCCAGAAGAACATGCAGCTGCAAACTGCACTGATGGTCAAAGACGAAATTACGACAAGGGTGAAATTAGAATTGTCAGAAGATGATGACAATGGAATATATTTTTTAGATGTGAAAGAAGAGGTGTCCGACTACGAACACTTAAGCGACGATGATGACGAGGATGAAAAGAAATTGGCCGAGATGCTCGGTTTTAATGAGATCACGGTGAAAAGGAGGAACGTCGACCAGAAGAATCGCTCGAGCAAGAAACGCGCCATCATGGCAGACTCAAATATTGAAAAGAAATCGAAAAAGATTACAAGTGGCCCCTTAAAAATATCAATCAGAGCTCTCTCAGAAATGAATAAGATCATGAAACCTGCGAAGGTGATGCCCAACGTACGGTTCATAAATGATAGCATGAAGCACAAATTGAACATAGACAACATACTCAAATACTCGAACTGTACGCCTTTTTCTAATAAAACTCTAGCTGGAATCGTTTGCGCTTATTGCAAAGACACATTTCAAAATATTGAAGAATTAAGAAATCATACGAGAGAAAACCACAGCGGCGTTGAATTGATTGATAAAAAGAGGATGGACAAAAATAACTTGtcggttaaagtggacatcactgatttaaaatgcagtacatgcttggcgagctttgacgtcataacgaatcttaagaaacatttgagcaaagaacacgacgtgaagttctactccgacgtgcataattacatcctagaatttaagttgactgatagtgaaatgttaaactgtgcgctttgtaattccactttcgagacattcaagatgctgttacagcacatgaatgggcattaccgaaactacatctgcgaggtttgcgacttaggtttcataaataaacatcggcttaaaaaccatcaaagaacacacgaaatcggcagtttcaattgtacgttttgtgataaagtgttcagtactcgagtcagaaagatgtgtcacgagaaatacactcacaactccggcgccaggtacaccaccaactgtccgcattgcgatcaatctttcacaagttactaccagaggaacaggcacatgttcaaagagcacaacatggtggcggcgtcttataagtgcaacatttgcgacaagtcttttattctgaagtcgaagctgacagctcatataaagaaagttcatttgatggagaggaatcacatttgtgccgagtgcgggcaaggattctttatcaagcagtctctggacgaacatatgataaagcataacggggaaagagtgtttaaatgtacagtgtgtcctaaagcatatgccaggaagaaaacattgcgggaacacatgaggattcacaacaatgacaggcgattcaagtgtggtatatgcgctttggcatttgttcagaaatgcagtctcaaaagtcacatgttgtccaaccatggtgTCACGTTGGCCGAGTACGAGACCTCTAGAAGTGATTTATGTAGCCCTGAGAGCCTCGAGTGTTAA
Protein Sequence: MSSVSMCRCCMLRPPDKKLKASYISLGKSEVYADMLKDCFEIHMAVGDVEGDGGICEVCIMRLRDACDFKQQVQRCQKNMQLQTALMVKDEITTRVKLELSEDDDNGIYFLDVKEEVSDYEHLSDDDDEDEKKLAEMLGFNEITVKRRNVDQKNRSSKKRAIMADSNIEKKSKKITSGPLKISIRALSEMNKIMKPAKVMPNVRFINDSMKHKLNIDNILKYSNCTPFSNKTLAGIVCAYCKDTFQNIEELRNHTRENHSGVELIDKKRMDKNNLSVKVDITDLKCSTCLASFDVITNLKKHLSKEHDVKFYSDVHNYILEFKLTDSEMLNCALCNSTFETFKMLLQHMNGHYRNYICEVCDLGFINKHRLKNHQRTHEIGSFNCTFCDKVFSTRVRKMCHEKYTHNSGARYTTNCPHCDQSFTSYYQRNRHMFKEHNMVAASYKCNICDKSFILKSKLTAHIKKVHLMERNHICAECGQGFFIKQSLDEHMIKHNGERVFKCTVCPKAYARKKTLREHMRIHNNDRRFKCGICALAFVQKCSLKSHMLSNHGVTLAEYETSRSDLCSPESLEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00787933;
90% Identity: iTF_00859757;
80% Identity: -