Basic Information

Insect: Sphinx pinastri
Gene Symbol: ZNF296
Assembly: GCA_947568825.1
Location: OX387616.1:1151649-1162311[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0082 0.68 11.1 0.0 3 23 120 140 118 140 0.96

2 15 0.0016 0.13 13.3 2.6 1 23 258 280 258 280 0.99

3 15 5.5e-06 0.00045 21.1 0.2 1 23 286 309 286 309 0.97

4 15 0.0012 0.1 13.7 3.9 1 23 314 337 314 337 0.94

5 15 5.4e-05 0.0044 18.0 2.6 2 23 494 515 493 515 0.97

6 15 0.00067 0.055 14.6 4.9 1 23 521 543 521 543 0.98

7 15 0.033 2.7 9.2 4.7 1 23 604 626 604 626 0.96

8 15 7.7 6.3e+02 1.8 0.1 2 23 634 655 633 655 0.93

9 15 0.0024 0.2 12.8 4.0 1 23 661 683 661 683 0.95

10 15 3.8e-05 0.0031 18.5 0.2 1 23 690 712 690 712 0.96

11 15 0.00077 0.063 14.4 2.9 1 23 721 743 721 743 0.99

12 15 0.00032 0.026 15.6 0.4 2 23 790 811 790 811 0.96

13 15 0.007 0.58 11.4 5.7 1 23 828 850 828 850 0.97

14 15 9.1e-07 7.4e-05 23.6 0.6 1 23 856 878 856 878 0.98

15 15 9.7e-07 7.9e-05 23.5 3.1 1 23 884 907 884 907 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0082	0.68	11.1	0.0	3	23	120	140	118	140	0.96
2	15	0.0016	0.13	13.3	2.6	1	23	258	280	258	280	0.99
3	15	5.5e-06	0.00045	21.1	0.2	1	23	286	309	286	309	0.97
4	15	0.0012	0.1	13.7	3.9	1	23	314	337	314	337	0.94
5	15	5.4e-05	0.0044	18.0	2.6	2	23	494	515	493	515	0.97
6	15	0.00067	0.055	14.6	4.9	1	23	521	543	521	543	0.98
7	15	0.033	2.7	9.2	4.7	1	23	604	626	604	626	0.96
8	15	7.7	6.3e+02	1.8	0.1	2	23	634	655	633	655	0.93
9	15	0.0024	0.2	12.8	4.0	1	23	661	683	661	683	0.95
10	15	3.8e-05	0.0031	18.5	0.2	1	23	690	712	690	712	0.96
11	15	0.00077	0.063	14.4	2.9	1	23	721	743	721	743	0.99
12	15	0.00032	0.026	15.6	0.4	2	23	790	811	790	811	0.96
13	15	0.007	0.58	11.4	5.7	1	23	828	850	828	850	0.97
14	15	9.1e-07	7.4e-05	23.6	0.6	1	23	856	878	856	878	0.98
15	15	9.7e-07	7.9e-05	23.5	3.1	1	23	884	907	884	907	0.98

Sequence Information

Coding Sequence: ATGAATGTGGGAATGGATATGGACCCTTTGAGTAACTTCGAATACCCAAACTATGATACATATGGGAACCTCGGAGTCCCATACTCATATGACCAAAGTGTGAAAGCAGAGATACCACAATACAACTATAACCAACCTATAATACCTCCACATACCAACCCAAGCACCGTAGAAGTCATAAACAACCAGCAACCAATCCAACCAGAGAAAGAAAGCATCCAAAATGAGACAGTTTTAAAACCAGATGGCGTTAAACCGGAATTGGACGGTAAGAAAATTAAAAAAGAGAAAATAAAAGGCAAAAAGAGCAGTTACTGGTCGGTAAAGATTCCAGACAAGGACTTTGCCTTCTACGGCTGCTCCGTCTGTGATATCAGCTTCGCAACTCTCCAGGAGTTAGACCAGCATGTCACTGTACATAAAGACAGGATAACCAGCTACGATCTCAGAGTACAGAATCAGATAAAAAAGAAACAGTTGAAGAAGCAAAAGAAGTTAAACAAGAAGGTAAAAGAGGAAAAAAAAGATATTGTATTGGAGATAAAACCTGAAGAGGGGTACATAGGGGAGGAAAAGGCTTCAGAATATAATGTAGGGGAAACTAATTCAAACAGTGTTAATAATGAGAATAACATGAACAATGATAATGAAGTCAATGAAGTAATTACGAGTTCGGAGAGTGAAATCCAAAAGAAGTTTATTAAGAATATTGTGAAGGAAGAGGAAAAGTGCCGAGAAATTGACAAGAATCTGATGAACCTGCAGAAGATTTACAAATGCTTTGCGTGTCAGAAACAGTTCTCGCTCAGTTATTATCTGAGGCTGCATGTCAGATCCCATACTGACGAGAAGCCGTACACGTGTCCGATCTGCGGGCAGTCGTTCATCACGGCAAGCAAGCTCGGGAGGCACAACAAGCGCATTCACCTCGCCATACGATATCAGTGCCGGATATGCTACAAGTTCTTCTCGCAATTTGATTTGTTAACGCGACACTTTGATAAGAAGCATCCGGAGGATAAACTAGAAGGAGAGCCTTACGACTACAACGCGATCCTGCCGTACCTGAAGGAGTTGGAGGAGCAGCTACGAGAGAAGTCTGAAGCGGAGAAGAAACCCAAAGACGAGGTGTGGGACGATCAGTGGGCGCCGGAAGCGGATCACTTGGACACACAGGCGCCGAAGGATGAAGGGAAGAACGAGCCAGACACGAAGGAGTTCTTCGTGGAAGTCGGGCCGGCGTCCGACATCGTGGTGGAAGAGGTGAAGGTGCTCCCGGATGAGGAGCCGCTCGTCAAGAACGAGGAGCATGATAACGCTGCCGATGCGCAGGATAGCATGGACGTTAAGGACGAGAGAGACTTCTCCGACGACGACTACTTCCCGTCGAACACGTGGGCGCGCGTGTCGCCTCCCCCCCCAGCCCCCTCCCCGTCGGACGCGCCCCCCCGGCGGCGCCCCCCCCGCGCGGGCCCGCTGACGTGCGAGGTGTGCCACAAGCGCATCAGCTCGCGCACGTACCTGCGCGTGCACATGCGCACGCACACGGGCGAGCGACCCTTCAAGTGCCACGTGTGCCAGCGCGGGTTCATCACCTCCAGCAAGATGCATCGGCACGCGCTCACGCACGAGGATCAGTGGAATGGTGACGTGGACGTTAAACGAGAGGGGATGAAGGAAGAGGACGATGAAAACGAGGAATCTGACGTTAAAACTGAAGGAGATGAAAGTAAAAAGTCAAAGAAGAAGTCGAAGAAACGGCCGAAGAAAGAAGGCGAGAAGCAGAAGAAACGGTACCAGAAGAGGCCGCACGCGTGCGAGTATTGTCAGAAGAGATTCCTTCACCTGGACACGCTGCAAGTGCACAAGAAGTCGCACGAGGGCGAGACGCTGGTGCTGAAGTGCAGCTTCTGCCTGGAGGAAGCGCCCGACGACGAGGCGCTGCGCACACACGAGAGCACCCACACGGGACCGAAGCCCTACCTGTGCACGCTCTGCGGCAAGAGCTACAAGAAGCGGGAGACGCTGGTGTACCACCGCAAGCACCACAAGCCGGACCGTCGCTCGTACATCTGCGACATGTGCTCGAAGCGGTTCGCGTCGCCCGGCAAGCTGCAGCGGCACGTCGTGTCGCACCGCGCCGACCGCTTCGTGCTGCGGTACGAGTGTCCCGTCTGCGCGCACATGTTCAACACCAAGTACCACGTGCAGATGCACCTCTCCACGCACCAGAAGGAGGGGCTAATAATGGAAGAGAACAGAAACGAAATCCTCGCAATGGTGCTTCAGAACGCGCGGAAGATTCCGAAGCAGCCCGACGCCCCCGCCAACCTCACGGACCTCATGCCCTCCGACGAGCGCAGCCGCGTGTGCAACATATGCGGGGAGGTGTTCCAGCACTTCTATTACCTCGAGGAGCACCTCAAAGGCCACGGGTCCAAAATAGCCATCGAGGACCTGGACAAGCCCGAAGAAAAGAAATACACCTGTCAAGTTTGTCAAAAATCATTCAAACTTCACTATTATTTGAAATTACACAGTTTCACCCACACTAAAGAGAAGCCGTTCATATGCCAACAGTGTGGGAAGGGTTTCATAACCAAAGGCAAACTCAAAAGGCACATTGAAACCCACACGGGGCTCAAAAAGTACCAATGCCACGTCTGCTACAAGTTCTTCACGAGACCAAGTTACTTACGCATCCATGTGAGGACTATACACGGAACGCAGGATTATAACTTCAGGCTGGATAAGGATTACGGCATGGGGTCCTTTGGGACGCTGTCCGTGATGACCCAGCTGACGCAAAGTAGTATTTAA
Protein Sequence: MNVGMDMDPLSNFEYPNYDTYGNLGVPYSYDQSVKAEIPQYNYNQPIIPPHTNPSTVEVINNQQPIQPEKESIQNETVLKPDGVKPELDGKKIKKEKIKGKKSSYWSVKIPDKDFAFYGCSVCDISFATLQELDQHVTVHKDRITSYDLRVQNQIKKKQLKKQKKLNKKVKEEKKDIVLEIKPEEGYIGEEKASEYNVGETNSNSVNNENNMNNDNEVNEVITSSESEIQKKFIKNIVKEEEKCREIDKNLMNLQKIYKCFACQKQFSLSYYLRLHVRSHTDEKPYTCPICGQSFITASKLGRHNKRIHLAIRYQCRICYKFFSQFDLLTRHFDKKHPEDKLEGEPYDYNAILPYLKELEEQLREKSEAEKKPKDEVWDDQWAPEADHLDTQAPKDEGKNEPDTKEFFVEVGPASDIVVEEVKVLPDEEPLVKNEEHDNAADAQDSMDVKDERDFSDDDYFPSNTWARVSPPPPAPSPSDAPPRRRPPRAGPLTCEVCHKRISSRTYLRVHMRTHTGERPFKCHVCQRGFITSSKMHRHALTHEDQWNGDVDVKREGMKEEDDENEESDVKTEGDESKKSKKKSKKRPKKEGEKQKKRYQKRPHACEYCQKRFLHLDTLQVHKKSHEGETLVLKCSFCLEEAPDDEALRTHESTHTGPKPYLCTLCGKSYKKRETLVYHRKHHKPDRRSYICDMCSKRFASPGKLQRHVVSHRADRFVLRYECPVCAHMFNTKYHVQMHLSTHQKEGLIMEENRNEILAMVLQNARKIPKQPDAPANLTDLMPSDERSRVCNICGEVFQHFYYLEEHLKGHGSKIAIEDLDKPEEKKYTCQVCQKSFKLHYYLKLHSFTHTKEKPFICQQCGKGFITKGKLKRHIETHTGLKKYQCHVCYKFFTRPSYLRIHVRTIHGTQDYNFRLDKDYGMGSFGTLSVMTQLTQSSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00859702;
90% Identity: iTF_00859702;
80% Identity: -