Basic Information

Insect: Sphinx pinastri
Gene Symbol: ZFX
Assembly: GCA_947568825.1
Location: OX387616.1:297545-305163[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 33 0.014 1.1 10.4 1.5 2 21 162 181 161 182 0.94

2 33 0.98 80 4.6 2.6 1 23 215 238 215 238 0.95

3 33 0.0096 0.79 10.9 3.0 2 23 244 265 243 265 0.95

4 33 1.7 1.4e+02 3.9 4.8 3 21 270 288 269 289 0.93

5 33 0.012 0.95 10.7 0.7 2 23 331 353 330 353 0.95

6 33 4.7 3.9e+02 2.5 0.4 3 23 361 380 360 380 0.89

7 33 0.0092 0.75 11.0 1.9 1 23 386 408 386 408 0.98

8 33 0.0013 0.1 13.7 1.7 1 23 414 437 414 437 0.97

9 33 0.071 5.8 8.2 0.9 2 21 554 573 553 574 0.94

10 33 0.36 30 6.0 0.8 1 23 604 626 604 626 0.96

11 33 0.00042 0.035 15.2 0.2 1 23 630 652 630 652 0.96

12 33 0.0019 0.16 13.1 2.5 1 23 685 708 685 708 0.94

13 33 0.00036 0.03 15.4 1.1 1 23 714 736 714 736 0.98

14 33 0.0064 0.52 11.5 4.3 1 23 743 765 743 765 0.98

15 33 3.9 3.2e+02 2.7 0.3 1 9 780 788 780 790 0.91

16 33 0.0017 0.14 13.3 1.9 2 22 897 917 896 917 0.88

17 33 5.3 4.4e+02 2.3 0.3 3 23 923 943 922 943 0.87

18 33 0.046 3.8 8.8 1.1 2 23 949 971 948 971 0.94

19 33 0.12 9.8 7.5 5.9 1 23 976 998 976 998 0.97

20 33 0.7 57 5.1 3.8 1 21 1001 1021 1001 1022 0.95

21 33 0.00037 0.03 15.4 0.4 1 23 1034 1057 1034 1057 0.95

22 33 2.5e-06 0.0002 22.2 1.9 1 23 1063 1085 1063 1085 0.99

23 33 6.7 5.5e+02 2.0 0.5 1 23 1119 1142 1119 1142 0.87

24 33 0.0023 0.19 12.9 0.7 1 23 1150 1173 1150 1173 0.94

25 33 0.0056 0.46 11.7 1.1 2 20 1284 1302 1283 1304 0.91

26 33 0.0043 0.35 12.0 0.6 3 23 1339 1360 1338 1360 0.97

27 33 0.00027 0.023 15.8 0.9 2 23 1366 1387 1365 1387 0.97

28 33 0.78 64 4.9 1.6 2 21 1391 1410 1391 1411 0.93

29 33 1.4e-06 0.00012 23.0 0.4 1 23 1437 1460 1437 1460 0.95

30 33 0.00063 0.052 14.6 0.5 1 23 1466 1488 1466 1488 0.95

31 33 0.11 9 7.6 0.1 1 23 1494 1516 1494 1516 0.97

32 33 0.0014 0.12 13.5 0.8 1 23 1522 1545 1522 1545 0.95

33 33 0.00041 0.034 15.2 1.8 2 23 1552 1574 1552 1574 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	33	0.014	1.1	10.4	1.5	2	21	162	181	161	182	0.94
2	33	0.98	80	4.6	2.6	1	23	215	238	215	238	0.95
3	33	0.0096	0.79	10.9	3.0	2	23	244	265	243	265	0.95
4	33	1.7	1.4e+02	3.9	4.8	3	21	270	288	269	289	0.93
5	33	0.012	0.95	10.7	0.7	2	23	331	353	330	353	0.95
6	33	4.7	3.9e+02	2.5	0.4	3	23	361	380	360	380	0.89
7	33	0.0092	0.75	11.0	1.9	1	23	386	408	386	408	0.98
8	33	0.0013	0.1	13.7	1.7	1	23	414	437	414	437	0.97
9	33	0.071	5.8	8.2	0.9	2	21	554	573	553	574	0.94
10	33	0.36	30	6.0	0.8	1	23	604	626	604	626	0.96
11	33	0.00042	0.035	15.2	0.2	1	23	630	652	630	652	0.96
12	33	0.0019	0.16	13.1	2.5	1	23	685	708	685	708	0.94
13	33	0.00036	0.03	15.4	1.1	1	23	714	736	714	736	0.98
14	33	0.0064	0.52	11.5	4.3	1	23	743	765	743	765	0.98
15	33	3.9	3.2e+02	2.7	0.3	1	9	780	788	780	790	0.91
16	33	0.0017	0.14	13.3	1.9	2	22	897	917	896	917	0.88
17	33	5.3	4.4e+02	2.3	0.3	3	23	923	943	922	943	0.87
18	33	0.046	3.8	8.8	1.1	2	23	949	971	948	971	0.94
19	33	0.12	9.8	7.5	5.9	1	23	976	998	976	998	0.97
20	33	0.7	57	5.1	3.8	1	21	1001	1021	1001	1022	0.95
21	33	0.00037	0.03	15.4	0.4	1	23	1034	1057	1034	1057	0.95
22	33	2.5e-06	0.0002	22.2	1.9	1	23	1063	1085	1063	1085	0.99
23	33	6.7	5.5e+02	2.0	0.5	1	23	1119	1142	1119	1142	0.87
24	33	0.0023	0.19	12.9	0.7	1	23	1150	1173	1150	1173	0.94
25	33	0.0056	0.46	11.7	1.1	2	20	1284	1302	1283	1304	0.91
26	33	0.0043	0.35	12.0	0.6	3	23	1339	1360	1338	1360	0.97
27	33	0.00027	0.023	15.8	0.9	2	23	1366	1387	1365	1387	0.97
28	33	0.78	64	4.9	1.6	2	21	1391	1410	1391	1411	0.93
29	33	1.4e-06	0.00012	23.0	0.4	1	23	1437	1460	1437	1460	0.95
30	33	0.00063	0.052	14.6	0.5	1	23	1466	1488	1466	1488	0.95
31	33	0.11	9	7.6	0.1	1	23	1494	1516	1494	1516	0.97
32	33	0.0014	0.12	13.5	0.8	1	23	1522	1545	1522	1545	0.95
33	33	0.00041	0.034	15.2	1.8	2	23	1552	1574	1552	1574	0.96

Sequence Information

Coding Sequence: ATGTCCCGACAAGTGGATGTAAAGGCATTAGTCTCCCATATAGTCAGAGGCGATGGCGCGGATAAATGCCGAATTTGTATGGGTGATACCTCCGAGGGTCAAGTATTCCTTGGCGACACAGTTATGATGGACGGAGACAAGGCGGTGACCCTCGCTGAGCTTCTAGAACTTATTACAGGCGTTGAGGTGGCTGAGGATGATGACCTGCCAAATGGACTGTGCAGAAAATGCTCAGCGTCTGCATTCAATGCTGCTGAGTTCCGGACATTCTGTCGTGAAGCATCTGAACGCTGGACCACCATTCTAGGCATGCTCAACATGATCCCCAAAAACAATTCAAAGAATATCTATGCTTTGATATTGGGCAACAAAATCTCCATATATGACAATAAAATGTTCAAAGAACCGCAGGAAAAGGCAAAGGAGGCTTGCCCAAAGGTTAAATCTATAAAACATAAAAATTATGCAAAAAGTTTGCATTGTCAGTGTTCAACTTGTGGGAGAAACTTCATGTACGCGAATGAACTGCATGCACATTTAAAAGAATCCATGGATTTGATCCAAGCTTGCTACGTTTGTGCCAAAATTATGAGTAGAGAGGATTTGATCAAACATTTGGTCCAAAAACACAATAAAAAACCACACCCTTGCAAGAAATGTTCAACTATATTAAATTCCTTCATGCAATACAAGCAGCACATGGTGAAGGAACACGGTCCTGGAGTGTGTACATGTGGGGATTGTGGGAGAACATTTCAGTCTACAAAAGCATATCATGCTCATCTGTCCATCCACGCACCTAAAAATTGTCCTCGTTGCTCAAAACTATTCCGAAATAAGAAATGCTATGTACACCATGTGAAAAAATGCTGTAACTTGCACAAAAACAGAAAAGAAGTGCATCAAACTAAACACAAGTTGTCCATACTAGTCAAAAACAAGGATAGACACATCAAAGTGGGTCTGCGAGGCAGTGCCGATAAGGAGTGCATTTGTGATTACTGTAAAAAACGATTTGCGGGAAAGAAGTTTGTTGCAGCACATATCCAAATAGTTCACTTAAAGAACACGCATAGACCATGTGCTTATTGTGGCAAGTTGCTTGCTGCTGCTCACATGTCGTCGCACATGAAGAAGCACCAGCCGTCACAGAGTTATAAATGTAGTCACTGCGATATTGTCCTAAAAAGTAAACTGGGCTACAGTCAACACTTGCGGCTGCACACTGGTGAACGACCATACAAGTGCCAGTACTGCGGAGAGACATTCACAGCGTCCTCAAGGAAGTCTGAGCACATCCGCAAAACACATAAGAGCACAGAAGAAGTGGGGACCAGCTCCGTGCTGCCAAATAAACTGTGCAAACTCTGCATGGCGCACATAACCGCTTTCATACCATTCCTGCTCCTGTGCAAGGTGTCCGCCCAGCGGTGGGACCAAATCACAGGAATGTTGAAGGATATCAAAGTCCCAAAAAAGGCCAAAAGTTATTATGTCTTAGTTCTAAAAGATATACGGACTTATTCTAGTACTAGAACCGCTGAGAGCGAAAAAGATGCTTTACAGAATTTGAAGACTAAGATAACAAATCGAAAATCTTATACCAAGAGGTTAGCAAAAGAGGGTCGCATGACTAGAATGAGGGATGCGACGAAAATGACGTGCCCCGAATGCAAATGTGTCTATACCAACATTGTAAAGTTTAATACACATATAAAAAACATAAACAAGAGAATGTGCGCACTCTGTAACGTTCTAATAGACTTGAAGACTTACGAGGCCCATTTGAACACTCACACTGGCAGGGTTTTTAGTTGTAATATGTGCCCCGAGGCATTTCTAAAAGAAAAGTCTTTGTATCTTCATAAATTAAAACACAAAGGAGACCATGTTTGTTTGGAGTGCAAGTTGAGTTTCGTGACGTCGGCGAACCTCTCCGCTCATTTAGTGATACACCAGTCGCAAGTGTGCGCTGGATGCGGTAATAAGTTCAATAGGATATGCTACACGAAACATAAACAAAAGTGCTCGTTTATAGAAGAAAATAGAAGATTCATCTGTGACTACTGTTCAAAAGAATACAACCGAAGAACTACGCTCAAGCTGCATATAATTCACAACCATTTGACTGGAAAGCAGTTTCAGTGTGACCAGTGTGGTAAGACGTTCCTCAGTCGCGCGCATTTGGTAGAGCACGGCAACACTCACAACAAAATTCCCGATCGATACGTCTGCTCGAAGTGCGGCACCAAGTTCAGCACCAGGAGAGGCCATGAGAGACATTTGAAGAAACACGAGTCTGGCACTTACGGAGTTAGGTCCAAGAAGAAGACCAAATATGTTTGCCCGATTTGTAAGAAGGTGCGAGAGGAGCCCGCGTTGCCGCAGGGTCTGTGCAGGAGCTGCTCCGAGCAGGCCATGGCCGCCGTGCGGTACCGGCAGCTATGCATCCAGTCCAACCAACAATGGAGAGACGCCACCGTCTGCCTCGCACAGATACACGCCGCCGCCGATGATGACAAAACCTTCTTCGTACTCTACAACGGACACATGATGATCATCAAGGACCAGGTCGCGCGCGTGCCGAACGAAACCGAGGCTGTGAAGAGGATCAACCTCAGATTCACTGATCCAGAGCCTCACCGGCCGCCCAAAAGAGTAAAGCGCTCATTCCCGCCTGTTAGTTGCCAATGCCCGGACTGCGGCAAGAGTTTTTCAAATACTGAGTTCTTAAACTTCCACCTAAAGACCTCATTGAAACGATCTTGTCAAATATGCGGCGTAGTCATGCCAAAAAAAAACCTGTCGAAACACTTGCTGGAAAAACATGACATATCAGTGGTGGAGTGTAGTGTGTGCCACAGCAACTTCGACACGCGTCAACAGCTCGAACAGCACAGCGCCACTTCCCACGGCCCTGACACGTATTCTTGTCATTGTTGCGGCAGCGGATTCAGCAACCACAGAGCCCTGCGCGCCCACATGTACTCGCACACGCTGTTTCATTGCGAGGCTTGTGGAGCGAGCTTCGAGAATCGTAAATGCTACAAGTATCATCAGAAACAGTGCAAGAGATCAGACGGACCGCAGCAAGACCTGTACATATGTGACTACTGCAATATAGAGTACAATAGGAAGCCGTCGTTACGAATCCATATGATTCAGAAGCACTTGAATATCAACCCGTACGTGTGCCAAGTGTGCGGCAAGAGGGCTTCGACGTTGTCGCACTTGAAATCGCACATGAAGACGCACAACGCGACGCGCAGCGTGTACCAGTGCCACTGCGGCGCGAAGATGCGTACGGAGGTCGGGTACCAGCTACACCAGCGGATACACTCGGGGGAGAGACCGTACGAGTGCGAGACGTGCGGCGATCGGTTCCTGTCGGCGTCGCGGCGGCTCGACCACATCAAGCGGAGGCACCGCGGCTCCGCAGACATGCCGCACGCCTGCTACAAGTGCTCCGCCACTTTCATTAGACCTTGGGAGCTGCGGAAGCACTACGTGACTGTTCACAACGATATAAAGGAAGAATCATTATGTCCGAACACGGCATGCGTGGCGTGTGCCAGCACGGCTCTGGCCGCGCAGGAATTCCGATACTTCGTCCAATCCTCGCATAACATGTGGAATAAAGCCATCACAAACCTCTCGGGGCTGCCAAGCACAATGTCTTCCCCGCTGAAGTCTCTCTGTGTGCTCATAACGCCGAACGACATGCGTGTACAGACAGTGAAAAACTACGCCAACGGTGATGCTAAAACTGTATTGAACAGGCTCAAAACAGGGATCGGTAGAAAGCCATTCGGGCGGAAGCCTCGTACCGACCGCACGGGTCCGTCGTGCACGTGTCCAGACTGCGGCAAGAGCTTCCTCAGTCCACACTTCTTGAACATGCACCTTATAAACAGTGGACAGAAGGAGGCGTGCGTGCTGTGTGGCGACGTGGTGTTACGCGGCCAGCAGATGAAGGAACACATGAGCGCCGCGCATCGCACCGACCTGCTGCTCTGCAATGAATGCCCGCTGTTGTTCTCCACTGAACAAGAGCTAGCCAAACACATAAAAATATGTCACCAAGCAGGTTGTTTAACGTGCGGTGAATGCGGCAGGAGTTTCCCGAGAAAAGTGGCCTTCGATCATCACACACAGATGCATATGGTGAGGACGTGTCGCAGCTGTGGCGCGCAGTTCACGAACCGAGGGTGTTACAGAGAGCACAGGATGCAGTGTGAGCCTGACGCGAAACCAAACATTGATAGTGTGCCTCGTGCTCGCCGCTCCAACATCCGCGACCCGGCGACCTACACATGCGACTACTGCGGGAAGACGTACTCGTCGAGGCCGCAGCTCAAGAACCACATCCTATGGATCCATATGGACGTACGCCCGCATCAGTGCCAGTGGTGTGGGAAGCGGTTCTACACGCCGGCTCGACTTGCCGAGCACACAGTGGTACACACGCGAGTGAGAAACTTTGAGTGCGACATCTGTGGTGCTAAATTGGTGACAAAAATGGCAGCGATATACCACAAGCGACGGCACACCGGTGAGCGGCCGTACAAGTGCGAGGACTGCGGGGAGAGCTTCATATCTTCCTCACGCAGATCCGAGCATGCCAAGCGGAAACACAATAGAGGCATAAAGCCGCAGTGCCATTTATGTCCGGCCAATTTTGTCAGGAAGCAAGAGTTGAAGAAACACATAGAAAAGAACCACCCGTGA
Protein Sequence: MSRQVDVKALVSHIVRGDGADKCRICMGDTSEGQVFLGDTVMMDGDKAVTLAELLELITGVEVAEDDDLPNGLCRKCSASAFNAAEFRTFCREASERWTTILGMLNMIPKNNSKNIYALILGNKISIYDNKMFKEPQEKAKEACPKVKSIKHKNYAKSLHCQCSTCGRNFMYANELHAHLKESMDLIQACYVCAKIMSREDLIKHLVQKHNKKPHPCKKCSTILNSFMQYKQHMVKEHGPGVCTCGDCGRTFQSTKAYHAHLSIHAPKNCPRCSKLFRNKKCYVHHVKKCCNLHKNRKEVHQTKHKLSILVKNKDRHIKVGLRGSADKECICDYCKKRFAGKKFVAAHIQIVHLKNTHRPCAYCGKLLAAAHMSSHMKKHQPSQSYKCSHCDIVLKSKLGYSQHLRLHTGERPYKCQYCGETFTASSRKSEHIRKTHKSTEEVGTSSVLPNKLCKLCMAHITAFIPFLLLCKVSAQRWDQITGMLKDIKVPKKAKSYYVLVLKDIRTYSSTRTAESEKDALQNLKTKITNRKSYTKRLAKEGRMTRMRDATKMTCPECKCVYTNIVKFNTHIKNINKRMCALCNVLIDLKTYEAHLNTHTGRVFSCNMCPEAFLKEKSLYLHKLKHKGDHVCLECKLSFVTSANLSAHLVIHQSQVCAGCGNKFNRICYTKHKQKCSFIEENRRFICDYCSKEYNRRTTLKLHIIHNHLTGKQFQCDQCGKTFLSRAHLVEHGNTHNKIPDRYVCSKCGTKFSTRRGHERHLKKHESGTYGVRSKKKTKYVCPICKKVREEPALPQGLCRSCSEQAMAAVRYRQLCIQSNQQWRDATVCLAQIHAAADDDKTFFVLYNGHMMIIKDQVARVPNETEAVKRINLRFTDPEPHRPPKRVKRSFPPVSCQCPDCGKSFSNTEFLNFHLKTSLKRSCQICGVVMPKKNLSKHLLEKHDISVVECSVCHSNFDTRQQLEQHSATSHGPDTYSCHCCGSGFSNHRALRAHMYSHTLFHCEACGASFENRKCYKYHQKQCKRSDGPQQDLYICDYCNIEYNRKPSLRIHMIQKHLNINPYVCQVCGKRASTLSHLKSHMKTHNATRSVYQCHCGAKMRTEVGYQLHQRIHSGERPYECETCGDRFLSASRRLDHIKRRHRGSADMPHACYKCSATFIRPWELRKHYVTVHNDIKEESLCPNTACVACASTALAAQEFRYFVQSSHNMWNKAITNLSGLPSTMSSPLKSLCVLITPNDMRVQTVKNYANGDAKTVLNRLKTGIGRKPFGRKPRTDRTGPSCTCPDCGKSFLSPHFLNMHLINSGQKEACVLCGDVVLRGQQMKEHMSAAHRTDLLLCNECPLLFSTEQELAKHIKICHQAGCLTCGECGRSFPRKVAFDHHTQMHMVRTCRSCGAQFTNRGCYREHRMQCEPDAKPNIDSVPRARRSNIRDPATYTCDYCGKTYSSRPQLKNHILWIHMDVRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICGAKLVTKMAAIYHKRRHTGERPYKCEDCGESFISSSRRSEHAKRKHNRGIKPQCHLCPANFVRKQELKKHIEKNHP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -