Basic Information

Gene Symbol
-
Assembly
GCA_037040025.1
Location
JBANCZ010001795.1:15222-19008[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0076 3.3 10.9 2.8 3 23 365 386 363 386 0.96
2 18 0.45 1.9e+02 5.3 0.0 1 23 393 418 393 418 0.94
3 18 0.15 66 6.8 1.4 2 23 429 450 429 450 0.93
4 18 5.7 2.5e+03 1.8 3.0 2 17 461 476 460 487 0.75
5 18 1.3 5.7e+02 3.8 1.0 3 19 520 536 519 540 0.88
6 18 0.00012 0.05 16.6 0.5 1 23 548 571 548 571 0.98
7 18 6.3e-05 0.027 17.4 0.3 2 23 576 597 575 597 0.97
8 18 0.94 4e+02 4.3 0.1 1 20 605 624 605 625 0.93
9 18 0.0012 0.53 13.4 0.7 1 22 645 666 645 669 0.90
10 18 0.63 2.7e+02 4.9 0.9 1 21 674 694 674 695 0.93
11 18 0.64 2.7e+02 4.8 0.3 1 23 714 739 714 739 0.94
12 18 0.16 70 6.7 4.1 2 23 755 777 754 777 0.93
13 18 0.0057 2.5 11.3 0.3 2 23 783 805 782 805 0.94
14 18 0.014 5.9 10.1 0.4 2 23 809 831 808 831 0.96
15 18 2.2e-05 0.0094 18.9 3.7 1 23 837 859 837 859 0.99
16 18 0.0098 4.2 10.6 1.1 1 23 863 886 863 886 0.94
17 18 3.8e-05 0.016 18.1 0.9 1 23 892 915 892 915 0.96
18 18 0.0021 0.88 12.7 0.7 5 23 928 947 919 947 0.84

Sequence Information

Coding Sequence
ATGtcggaaaatttgaaattaaataacgAAAGCAGGCAATCTGAGCCTAGCTGCTTGCATTGCGGTGTTCGGAATTCAAACCAGAATTATCAGCCGATATTCGATGATGTGGGCATAGATATCGAATTACCGCAACTATTAGCCAAATACTTTCAGCTGAATGTGAAGCCAGATGCAAATAAGGCGCAATTATTGTGTATAGAATGCGTAAATACGCTCATACGTTTCTTTGATATTGATGaactgcagcaggagcaggatgCAGCCAATGCTGCCAGAGCTGCAGCTGGCAAAGAAACAAAGCCACAAACATCTAATGCAGCCCTGACATCGCCTGCAGCCAAAAGAGcagcgaaacgaaaacaaacatCGCCTACAGCTCGGGCATCTACAGGCGGCAAATCTGCTATAGTCACCAGAAATGCTTCACCAGCAGCGAAAAGAGCAGCCGTCAAGGTCAATACAACGGCGTCAACAGCACCAactactgctgctcctgctacggtttttgctactgctgcagcgcctgctCTGCGCATAACTAGGACCAAAACATTGGCTGTAAACAAGCCGAAATCAAATAGATCACTGGGCGTTAAAGTGGCAGATAAACGTCGGAGTTCTAGAGAAGCTGCTGTCGGTGAGCAGGAGCAGATCAGTGCCATGATACGTGATATATTGGAAGATGGAGAAACACCGACAGCGGAACAGTTCGTTGAGGCAGCGGCCACAGTGCGAAAACTGGAAAAACAGCAATTGGAGCAGGAGCAAATGGTGGAGCAGATTgaggaagagcagcagcagcaacagtcacaacagcagcaacagcagaatgACGACAATGTGGATTATCTAGAAGACGGTTCCTATGACATAGATGTGCAGCAATTCAAGGTGGAACAGAGTACCACGCCGACGCTTTCGTTTTCGGACGAAGAGATGCCCAGTGGTGAGGAGGATGAATCCGTTAAAGTGGAGCCCTTCAATTTTGTGCTGATTAAGGAGAATGATGACATTGGGGATCTCTATGAATACTTGGCCACTGCAGTCAAGACGTGCTTTGAAACGTTATCCTTTGAGTGGGCCATAGATTGCACTCACTGCGGGCTGAAGTGCAGCAGCTATGAGCAGCTGCTGGGGCATATGTTGAAGCGTCATGCACTGTCCAAGCAGCGCTTCAAGTGTCCCATTGAAGGCTGCCAAATGGAGCTAAAGAATATCAAATCGTTGGCCATGCATTTGGTGGTGCTGCATGCGCCGGTTGCAGACATACCCATTTATGGTAGCTGTCCCGAGTGCAGCATTAACTTCTCCAATATATTGCAGTATAATAAACATTCCTGCGCACATGTTATCAAAAAGCGACGCGGCATGCGACTCTATTGCGAGATGTGCGGCTTAGAGTTTCCCTCCTGGAAGCGCTTCAACTTTCACAATCAATTCCATTTGGAGCGTCACAGGCCACGCGCTTGCTTTGTATGCAActatgccaacaacaacatcgatgAGCTCTTTCAGCATTTGCACTATGCCCACGAGCCGGAAGGCACGCTGCTCTGTGATCTCTGTGATCGCCAGTTTCGTGATGCTGCTGTCTTTGCCGAGCATAACAAATGCCATACGAATGTGAGCAGCACCGTCTACACCTGCACGGATTGCAATGCAAACTTCGATACACGTGGACGCCTCAATGGACACATGCGTTCCATGCATGGCACTGTCATTAGCTGCGAGCTGTGTGGCAGGGAATTCGCCACAGAAGCCACATACAATTCGCACATGAAGAAGCATTTGATAATCGAGCGTGAGGTGCACGTGTGCAGCAATTGCGGACTTCTCAGCGAGAATAACGATAAACTTGTTGCTCACGTGTCCGATCAGAGTTCGAATTGCTTTGGTGTTGATATTGAGACGGAGCTGCTGCGCGATGCCTATGTATGTGAATATTGCTCGTCGTATTTCAAGCAAAAGACTGATTTGCGTGCTCACCGCGACTCGGGCGTGCATAAGGATGGTTTGTTCTACTGTCAGCCATGCGACAAGGAATTTGGCGAAATGAAACTCTATCGTCATCATATACGCAactatcagcagcagcgtgcAGATGTGGCACATCGCAAACTGGAGatttgtttatactatatgtgcGATTTTGAGGATTGTGTTGATGCGTACATCAATTGGAATTCATTGTATACGCACAAGCGACGAACGCACGATACGGCAGCAAAGCAGGAGGCCGCAGCGAAGGCGGATGAATGGATTTGCCAGTTCTGTCAGAAGCATTGCCGCTCCAAGATGTCGCTCTCAGTGCATGTGGCACGCAGGCATAACAATAATAATGTGGTCTGCACGCTGTGCAGCGCCTCGTATAAGAATGAAGAAGCGCTGAAGGCGCATCATCAGTATTGGCATGAGCCCATGGAGTGCAACTTGTGCCTTAAGATACTCAAGAATCAGCGCAATTATGACACCCACATGAATGTGGTGCACTCGAACAGTCAGCGCTATAAATGCGGCGTTTGTCACAAGGGTTTCTATCACAAGAGCGAAATGGAGGCCCACCAGCGTCTACATTCGCAGCTGTTCTCCTGCGATCAGTGCAGCTTCACGACGCGCAACAAGAAATCGCTGTCGGTGCACGTGATGGGGCAGCATTTCAAACGCTTTGCCTTTGCGTGTAGAATGTGCGATAAACGTTTTGGCCGTCGCCAGGGCTTGACCAGTCACATGCAGCGTGTACACGGCTCCAAGTTTATGTGTCGCAATTTCTATGAGCAAGGCTGCAGCAAGGTGTTCACGACCACAACGGGACTCAATGCGCATGTGCGGAAGCAGCATGGCGTTAATCTGTTGCTCATCGATAAATTGGAAAAAGTAGGTGACGAGGAAGACGAATTAGAGGAGTGCGAGAGCGAGGAGCAGCTGGAGTTGGAGGAGGTACAGCTGGATGAGGGACCATCGTCGTCAAAGAAGCGTTGCATTCGTCTCAGTGCTGATACGCAAATTGAGTTCATTTCAGGCGATCCCAATATCAATGAGGACAACGATGAGATTCTTATAAGCCCACCCAGCCAAGAGCATCATAGTGCAGCATCGATAAAGCTGGAAATAGTGCCGTCCAAGCAGCGTCAGCAGCCCAAACGTAAAacataa
Protein Sequence
MSENLKLNNESRQSEPSCLHCGVRNSNQNYQPIFDDVGIDIELPQLLAKYFQLNVKPDANKAQLLCIECVNTLIRFFDIDELQQEQDAANAARAAAGKETKPQTSNAALTSPAAKRAAKRKQTSPTARASTGGKSAIVTRNASPAAKRAAVKVNTTASTAPTTAAPATVFATAAAPALRITRTKTLAVNKPKSNRSLGVKVADKRRSSREAAVGEQEQISAMIRDILEDGETPTAEQFVEAAATVRKLEKQQLEQEQMVEQIEEEQQQQQSQQQQQQNDDNVDYLEDGSYDIDVQQFKVEQSTTPTLSFSDEEMPSGEEDESVKVEPFNFVLIKENDDIGDLYEYLATAVKTCFETLSFEWAIDCTHCGLKCSSYEQLLGHMLKRHALSKQRFKCPIEGCQMELKNIKSLAMHLVVLHAPVADIPIYGSCPECSINFSNILQYNKHSCAHVIKKRRGMRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCNYANNNIDELFQHLHYAHEPEGTLLCDLCDRQFRDAAVFAEHNKCHTNVSSTVYTCTDCNANFDTRGRLNGHMRSMHGTVISCELCGREFATEATYNSHMKKHLIIEREVHVCSNCGLLSENNDKLVAHVSDQSSNCFGVDIETELLRDAYVCEYCSSYFKQKTDLRAHRDSGVHKDGLFYCQPCDKEFGEMKLYRHHIRNYQQQRADVAHRKLEICLYYMCDFEDCVDAYINWNSLYTHKRRTHDTAAKQEAAAKADEWICQFCQKHCRSKMSLSVHVARRHNNNNVVCTLCSASYKNEEALKAHHQYWHEPMECNLCLKILKNQRNYDTHMNVVHSNSQRYKCGVCHKGFYHKSEMEAHQRLHSQLFSCDQCSFTTRNKKSLSVHVMGQHFKRFAFACRMCDKRFGRRQGLTSHMQRVHGSKFMCRNFYEQGCSKVFTTTTGLNAHVRKQHGVNLLLIDKLEKVGDEEDELEECESEEQLELEEVQLDEGPSSSKKRCIRLSADTQIEFISGDPNINEDNDEILISPPSQEHHSAASIKLEIVPSKQRQQPKRKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-