Basic Information

Gene Symbol
-
Assembly
GCA_009176505.1
Location
VUAH01000002.1:7019157-7020811[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 9.9e-05 0.0059 17.1 0.2 2 23 177 198 176 198 0.97
2 8 2.4e-05 0.0015 19.0 2.8 1 23 204 226 204 226 0.93
3 8 0.036 2.2 9.0 1.9 1 23 233 256 233 256 0.96
4 8 2.8 1.7e+02 3.1 1.7 3 23 266 288 264 288 0.93
5 8 0.00028 0.017 15.7 4.6 1 23 295 317 295 317 0.98
6 8 2.5e-06 0.00015 22.1 2.0 1 23 323 345 323 345 0.98
7 8 0.00012 0.0069 16.9 2.5 1 23 352 374 352 374 0.97
8 8 4e-06 0.00024 21.5 0.4 1 23 380 403 380 403 0.97

Sequence Information

Coding Sequence
atggaaaaaaaaccgactgAAGAGCTAGAACAATGGTTTTTTCGAATAGAAACAGCAATTGCTGGCTGTGATTTCGGAGATTTTACCCATTTCATGTTGatcgataaatttatttgtggATTAAGTGaggaaatattcgaaaaatattccaaaaccAGTGTATTGGACGTAGAACAACTACTATCAATTGGAACATCAGACACATTCCTTCTGAATAATTCCTTTGCCGGCACCAAATTCGAACCAATCAAAGACATCGATGAATTACTTTCGCTGGAAATAGTTGGAAGCAACGTTTTGAATGGAGATGAATATGATTTGAAGAATGATAACGGTGCCCAGTCAAATAATGACATCTATCCGGAAGATAgtcaaataaatgaagaacAGTTGGCAGAAGAAATCATGGAATCGGACTTGATTGAAAACGAGGAAGATAATCCCAAAATGAGTGATTGCCCTACAGCTCTAGACAAACCACTTCAAACTCATATCAAAGGATTTCTGATTGATGCACAAAATAGGATCGTATGCTTGGATTGTGACAAAATTTTTGCGTTGAAATCTTCATACAACATACACAAacgaatTCACACTGGCACCAATTTACATCGATGCAAAGTATGTGATAAGATTTTTACCACCCGCAGCAAGATGCTACGACACATGCCAACGCATGATAATGATGGACGCAACTTTGAATGTTATTTGTGTTCGTTTCAGTTCGATCAATTTTATGCTTTGCgaatacatttcaatatgaaaCACTTGATGTCGAAAGAGGATGCAATCCACTGTACCATTTGCAATCCTAAGAGGACATTTTTGAGCCGAAATGCGTTCGATCGTCATTTGAAAGTTCATCAAGGATTGACGCAAACACACAAGTGTCCACACTGTGACAGAGAATTCGAAAAACGTGGCAAACTGAGTGAGCACATACACGTTCATTCAGATTTCAAGCAATTTGTCTGCGAATCGTGTGGAAAAGCCTTCAAGACACGCAAACAACTGAAATTACATTCGCGAAGACACAGTGAGAAGCCGTTGAAGTTCAATTGTTCCGTGTGTGAAAAACGATTTGCCACCATGtatcatttaaaaattcataaatcaGTCCACACGGGCGAAAAACcatacaaatgcaaacaatgcgaccgcgcatacacacaactTGGTACACTCAAAGCACATCAAGCCAAAGCACATTCGAATTCAACACCTGGAAATTCTGAATTAGTATAG
Protein Sequence
MEKKPTEELEQWFFRIETAIAGCDFGDFTHFMLIDKFICGLSEEIFEKYSKTSVLDVEQLLSIGTSDTFLLNNSFAGTKFEPIKDIDELLSLEIVGSNVLNGDEYDLKNDNGAQSNNDIYPEDSQINEEQLAEEIMESDLIENEEDNPKMSDCPTALDKPLQTHIKGFLIDAQNRIVCLDCDKIFALKSSYNIHKRIHTGTNLHRCKVCDKIFTTRSKMLRHMPTHDNDGRNFECYLCSFQFDQFYALRIHFNMKHLMSKEDAIHCTICNPKRTFLSRNAFDRHLKVHQGLTQTHKCPHCDREFEKRGKLSEHIHVHSDFKQFVCESCGKAFKTRKQLKLHSRRHSEKPLKFNCSVCEKRFATMYHLKIHKSVHTGEKPYKCKQCDRAYTQLGTLKAHQAKAHSNSTPGNSELV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-