Snig000830.1
Basic Information
- Insect
- Sisyra nigra
- Gene Symbol
- topi
- Assembly
- GCA_958496155.1
- Location
- OY292313.1:12609969-12615692[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00048 0.039 14.6 0.8 2 21 146 165 145 166 0.94 2 13 0.00016 0.013 16.1 4.1 1 23 190 212 190 212 0.98 3 13 0.00012 0.0099 16.5 0.3 1 23 218 240 218 240 0.98 4 13 0.0017 0.14 12.9 1.3 1 23 410 432 410 432 0.98 5 13 0.27 22 6.0 0.4 1 20 438 457 438 459 0.91 6 13 0.0088 0.71 10.7 1.8 3 21 476 494 474 498 0.88 7 13 0.012 0.96 10.3 0.2 1 23 860 883 860 883 0.95 8 13 0.24 19 6.2 1.6 3 23 889 909 887 909 0.92 9 13 1.3e-06 0.00011 22.7 2.5 1 23 915 937 915 937 0.98 10 13 0.032 2.6 8.9 0.2 1 23 943 968 943 968 0.96 11 13 0.17 13 6.6 1.8 1 23 974 996 974 996 0.85 12 13 1e-05 0.00085 19.9 0.4 3 23 1004 1024 1002 1024 0.97 13 13 7.7e-06 0.00063 20.3 1.8 1 23 1030 1053 1030 1053 0.98
Sequence Information
- Coding Sequence
- atggaGCAAAACGATATTTTTCTCAAAGTTCATAACATGGAAGACAATGGCGTGTTGCAggaaattcaaattgaaaatgatgTTCAAAATCAATTACTTTCTCAAGCGCTTATGTCGTCCCAAGAAATAAAAGTGGACGAATCATCAATGCAATGGGGGTACGTAATCGACACCGATTCAAAATTAGATATCAAACTACAAAACTATGAAACAAAACCAGCGACAATAACGGTAATTAAAATTGGCGGAATCGAGGATTTGAatccgttaaatttttcatcatgCGTGCCATCGTTAAATCCACTGCATCAAGTTGTGCTTCAAGATAATATTCTAGTGGAACAAATTCAAGAATCTCCCATCAATATTCCACGAATCAAAGATAGACCTAAGAAAAGCTATGTACACCAAGTTCCGACGACGGAACCTGCCGTCGTTTGCCAAAATTGCGATGCTTCATTCCCCACAAAATATCAGTATCAGCGTCATCAATGCGAATTTAATGCGTCCAGAGTTACATTGAAAAGTGAACTACCGAAAAGAAATATCGAAAAACCTAAAACCCGATATGAATGCGATATTTGCCATAAATCTTTTATGACTGATCATAATTTGGATCGACATCGTCTTTCGCATGGCGACACTAAGCCTTATACATGCCAAAATTGCGGAAAAGGTTTCGTACTTGAATCAAGACTAAATACTCATATTGAAAGCCATTGCAGATTATCTACAAAAGAATCGAAACGTTTTTACCGCACCGATTTAACCGTTTGGCAATGCTTCAATTGTAAATTGATTACTGCCACTGAGCCgcaaaatttaattcatatttgCGATAATTTGAACCCATCCTTTGTATCCGCCAAGAAATCTTTACCCCCCGAAAATAATCCAggagaaaataaagaaaatattgatcCATTGGCCACGTCACAATCCCCATCAGAGCAAAAAACTCCCAATAATTTCGATAATATGTACAATACacccaaaataattaaaattttaggagAACGAAATTCAAATGTCCATGTTTTCAATGGACAAACTGTACCGAGCCAAAAcaatttcgataaaaattttgaaaaagcaaTCGATGGTATGGATGATAACTCTGCGAATGAAAATGCCATATTTAAAAATCCTACTTTTGATAATAAATCATTCGTAACAAACATAGAAAATATCGATCATCGATTTAAACGAATCAGTGTTGAACAATTATTTCAATGTGAGTTTTGTAATCGAACTTATGccgataaaaatatattaaaggaTCATCAAAATTCTCATACAACGGATAAAAATTATCAGTGCATGTTTTGTGAAGAATCGTTTGAGAGCTATACTAACGCCTTAGTGCATTGGCAACATAAATGCGATGATAAATCTAATTTATTCTGTCTTCCAAAGATCATCATATGCAAATTTTGTGATAAGGGTTTTAAAtcacacgagttattatacgcTCATAAGTATAAACTAAAACATTTTCTCCCGAAAGTTTTTAATAATCCTGAACTTTCTGCAACAATCAATAATAATCCCAATGAAGTGACCAATATTGCGCAATCATATAACTCTCATGTGGAAGAACtaaataataactttaaaaataattttgaactaAACCAATATAATGCAATAAACAATGGAGACGTTTATAAcgattcaaattcaatcacttACAATGTAAATAATGGATTTAGTACAGTAACAATAACTGAGTTTGTTAAGGAAAATCAAGAACAACCGTTAAGACCGCTTTCAATAAACGAACCCAAAAATATGTACGGCTGCGAAAATTCAGATATTGTCCACTTTGAAGATAGCATGGACATTGAAAACTTTGATTGcgacacaaaaaattttaaggacaaaataaatgcatttagcGAAGAAGAAATTCATGATCATATCATGTCTACCGTTCACCCTGATAATTGTTCACATGAACTTATGCAAATTGATGAGTTCTTGAACGACATAGCCAATAAAGTGTTGAACAAATCAGAGCCGATTCAGAAATTTAAAGAAACGAATCCTTCAATTACTTTTGAAAATGATGAAGATAAGAATGAATCAAACTCAAATCGAAAGCACTTGAAAAACTCTGTTAAGCGGAATGAAAAAGAAACAATGTTTAATGGAAAATCTGATAAAAAACTCGTGaaagattttgaaataaaagaaaaagacGTTGAAACTCGTATGCGAACCCGAAATATGGAgcgaatgaaaaataaaaacaaaggaAATGAATCAGAACAGGAAAATAAAGAcgggaaaaagaaaaaaagtaaagaaGATGCATCTACAGATAAAATGGATGAGAAAGAAAGAACCGAATTTAGTGATACAGAAGAGTctgataaaaaaagaaatttaaagaagaaacaagataaaaacttaaatattaaagaagAGGAGTTAATTGTTGAAGAGAACAAGGAAAATGTTGAAGATAACAATTTGAAGCAGTTAACTGCTGTTACCCCAGTGAAACGAGGAAGAAAACCGAAACCAAAAATGCTAGCAAATGAAGTGATTTCGTCTTGTGAAGATGGTTTTCGATTTCAATGTGAAAAATGTGCAAAAGTAACACGGAGCATTAATGAGCTGATGGAGCATCGTCAAGCTGATCATGGTAGTAAATTTGGGTGTAAGGATTGCGGACAGGTCGTGCATAGTTCAAAAGCTTTAATGATACATTGTCGTGCACACCAAAGCTTGAAACCATTTGTTTGTGATCAATGTGGTCGTAGTTATTCGCAAACATCTCATTTATGGCAACATATGAGATTCCATCAAGgaaTAAAACCCTTTGCTTGTCCTCACGAAGGATGCGAAGCACGTTATACAATTCGTCCAGATTTAAAGGATCATATAAGAAAAGTACATACACGAGAAAGACCTTTTCGATGTGCCGTTTGTGGTAAATGTTTTTTGACTGGTTCCGTTTATTATCAACATCGATTGATTCATAATAACGACCGAAGATATGGATGTGAGttgTGTGGAAAAAGATTTTTCCGTGCGGATGCATTAAATAATCATCGTCGTATTCATACTGATGAACGACCGTTTCCTTGCCCTGTTTGTGGTCGTGAGTTTCGACAAAAAGGGGATAGAAATAAACATCATAGAACACAACATCCTAATGAAATGGCTTTGAATTTATCAACTTCTTTACCTAATTag
- Protein Sequence
- MEQNDIFLKVHNMEDNGVLQEIQIENDVQNQLLSQALMSSQEIKVDESSMQWGYVIDTDSKLDIKLQNYETKPATITVIKIGGIEDLNPLNFSSCVPSLNPLHQVVLQDNILVEQIQESPINIPRIKDRPKKSYVHQVPTTEPAVVCQNCDASFPTKYQYQRHQCEFNASRVTLKSELPKRNIEKPKTRYECDICHKSFMTDHNLDRHRLSHGDTKPYTCQNCGKGFVLESRLNTHIESHCRLSTKESKRFYRTDLTVWQCFNCKLITATEPQNLIHICDNLNPSFVSAKKSLPPENNPGENKENIDPLATSQSPSEQKTPNNFDNMYNTPKIIKILGERNSNVHVFNGQTVPSQNNFDKNFEKAIDGMDDNSANENAIFKNPTFDNKSFVTNIENIDHRFKRISVEQLFQCEFCNRTYADKNILKDHQNSHTTDKNYQCMFCEESFESYTNALVHWQHKCDDKSNLFCLPKIIICKFCDKGFKSHELLYAHKYKLKHFLPKVFNNPELSATINNNPNEVTNIAQSYNSHVEELNNNFKNNFELNQYNAINNGDVYNDSNSITYNVNNGFSTVTITEFVKENQEQPLRPLSINEPKNMYGCENSDIVHFEDSMDIENFDCDTKNFKDKINAFSEEEIHDHIMSTVHPDNCSHELMQIDEFLNDIANKVLNKSEPIQKFKETNPSITFENDEDKNESNSNRKHLKNSVKRNEKETMFNGKSDKKLVKDFEIKEKDVETRMRTRNMERMKNKNKGNESEQENKDGKKKKSKEDASTDKMDEKERTEFSDTEESDKKRNLKKKQDKNLNIKEEELIVEENKENVEDNNLKQLTAVTPVKRGRKPKPKMLANEVISSCEDGFRFQCEKCAKVTRSINELMEHRQADHGSKFGCKDCGQVVHSSKALMIHCRAHQSLKPFVCDQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFRCAVCGKCFLTGSVYYQHRLIHNNDRRYGCELCGKRFFRADALNNHRRIHTDERPFPCPVCGREFRQKGDRNKHHRTQHPNEMALNLSTSLPN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01349922;
- 90% Identity
- -
- 80% Identity
- -