Snig008754.1
Basic Information
- Insect
- Sisyra nigra
- Gene Symbol
- ZFX
- Assembly
- GCA_958496155.1
- Location
- OY292315.1:29199628-29200941[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 3.5e-06 0.00028 21.4 0.9 1 23 11 33 11 33 0.99 2 11 2.8e-07 2.2e-05 24.8 0.4 1 23 39 62 39 62 0.96 3 11 1.4e-05 0.0011 19.5 0.8 1 23 72 94 72 94 0.98 4 11 2.1e-07 1.7e-05 25.2 1.3 1 23 100 122 100 122 0.99 5 11 0.0098 0.8 10.5 4.7 1 23 128 150 128 150 0.98 6 11 3.2e-05 0.0026 18.3 0.1 1 20 156 175 156 176 0.96 7 11 0.0075 0.61 10.9 5.6 1 23 185 205 185 205 0.98 8 11 3.7e-06 0.0003 21.3 0.1 3 23 213 233 212 233 0.99 9 11 1.8e-05 0.0014 19.1 2.0 1 23 239 261 239 261 0.99 10 11 0.47 38 5.2 1.9 1 21 267 288 267 291 0.84 11 11 0.34 27 5.7 0.2 3 21 299 317 297 318 0.87
Sequence Information
- Coding Sequence
- ATGACAAATACCAAAGAAAAACCACGTAAATATCAGTGTGAAGAGTgtggcaaatattttttaagtaacaatGATTTGCGAAAGCATCTCCGTGTTCATTCCGGCGAGCGGCCGTACGAGTGCAAAGAATGTGGCCGACGGTTTCGACAAGCTGGTAGCTTAAAAAATCATCTCGCTTCTCAACATTCGTTAGGTGTGGAATTCTcagaaattttcatttgtaactATTGCAACAAATCATTTCCAATCAAAGAACGTCTTCGATTACACTTAAGAATACATACCGGAGTAAAGCCGTACTCATGCACGCATTGTGATAAATCATTTGCTCGCGGAGGTCAATTGGTGCAGCATATTCGGACCCACACGGGCCAAAGGCCCTACTCTTGCCAACATTGCGATGCTAGTTTCACCTGTATTGCTAACCTGAAGTTGCATACTAAACGCCATTTTGATCTTCGAGATTACATCTGCGATATTTGCGGAAAATCATTTCTTCGACCCGATGCCCTAAAGAAACATTTAACATGTTTTCATGGAAATGTCCGGGCGTTCCACTGTTCCGTATGTAACAGAGAGTTTAAGGGCCATTTGTCTCAGCACATGCGCACGCATAAACAAGACAAACCGCACGGTTGTGCCATCTGTGGAGCGAGATTTGCACAACGATCTCAACTAACAGTGCACCAACGGGTACATAGTGGAGAAAAACCCTATCGATGTCAAGTTTGTTGGAAAGCCTTTGGACATTCAACCGCGTTAAAACTTCATACACGACGTCACACTGGCGTAAAACCATTTAAATGCTTACTATGTGCAAATGTTGCATTTTCTCAACTTCCACATTTAAAGAAACACATGCTTTGTATTCACAAAACAAACAAACCATATCTTTGTATTTATTGCGATGGCTTTTTCAAGACCAAATACGATTTGGATGGCCACCAACAAGAATGCAAGGCTATGAAAAATATACCCGATACGGCAGATGATGTAAAATCAGAACCAGTTGTTGAACCGCCAATGCCGATTGAACGAATGCGTCTTCTGTTGGccgtattattaaaaaaaatttcatctcaAAAACGACTGGATGAACTAGGATTTAATAAGCGTCTAATAGACGATGTTTTACACGATTCGATCAAAGGTTCTGGCCGTGAACCTTGTGAAGATAGCACCCTTACCGAAGCCGAGCGATTGAAAAACAATGTACAAATTCTTCTCGATTGGACTGTTCCGAAACAATATATGGATAAGTTCAAATTGGAACATAGATCAACGGAAGAACTACTGGAAGAACTAACATCATAA
- Protein Sequence
- MTNTKEKPRKYQCEECGKYFLSNNDLRKHLRVHSGERPYECKECGRRFRQAGSLKNHLASQHSLGVEFSEIFICNYCNKSFPIKERLRLHLRIHTGVKPYSCTHCDKSFARGGQLVQHIRTHTGQRPYSCQHCDASFTCIANLKLHTKRHFDLRDYICDICGKSFLRPDALKKHLTCFHGNVRAFHCSVCNREFKGHLSQHMRTHKQDKPHGCAICGARFAQRSQLTVHQRVHSGEKPYRCQVCWKAFGHSTALKLHTRRHTGVKPFKCLLCANVAFSQLPHLKKHMLCIHKTNKPYLCIYCDGFFKTKYDLDGHQQECKAMKNIPDTADDVKSEPVVEPPMPIERMRLLLAVLLKKISSQKRLDELGFNKRLIDDVLHDSIKGSGREPCEDSTLTEAERLKNNVQILLDWTVPKQYMDKFKLEHRSTEELLEELTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00239672;
- 90% Identity
- iTF_01349888;
- 80% Identity
- -