Basic Information

Insect: Sipha flava
Gene Symbol: Mtf1_1
Assembly: GCA_003268045.1
Location: NW:291349-302650[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 5.1e-05 0.0044 16.9 2.9 1 23 102 126 102 126 0.94

2 6 3.1e-05 0.0027 17.6 0.3 1 23 132 156 132 156 0.98

3 6 9e-05 0.0078 16.1 0.8 1 23 162 186 162 186 0.97

4 6 2.1e-06 0.00019 21.2 3.9 2 23 192 215 191 215 0.90

5 6 2.8e-05 0.0024 17.7 3.1 1 23 221 245 221 245 0.98

6 6 4.9e-06 0.00043 20.1 2.1 1 23 251 275 251 275 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	5.1e-05	0.0044	16.9	2.9	1	23	102	126	102	126	0.94
2	6	3.1e-05	0.0027	17.6	0.3	1	23	132	156	132	156	0.98
3	6	9e-05	0.0078	16.1	0.8	1	23	162	186	162	186	0.97
4	6	2.1e-06	0.00019	21.2	3.9	2	23	192	215	191	215	0.90
5	6	2.8e-05	0.0024	17.7	3.1	1	23	221	245	221	245	0.98
6	6	4.9e-06	0.00043	20.1	2.1	1	23	251	275	251	275	0.97

Sequence Information

Coding Sequence: ATGGAACAACCTGTGGTTGCGCTCGTTTACAACGACTTGGATCTGCAGCACGAACCTACGCCGCCGccacagcagcagcagcggccGCGAACGACGGAAGAAGACGACGGAGGAGAGGACGGCACCAACGCGTACTGTAACGCCGGCTACAGTTTTGTCCATTATGACTTCCAAACAAATAGTTATGCACAGTATGACGTTAATCCACAAAATGATGGAACTTCACAAGAAGGATTTCATGATGATTTATCACAAAGTTCGCTTAGTAACGATATTCCACCTGATCAGTCGGACACTAAAAGACATAACTGTGAATTCACTGGCTGTAAAAGGACGTATAGTACCGTAGGAAATTTACGAACTCACATGAAGACACATAAAGGCGAATATCGGTTTAAGTGTAACATTATGGACTGCGGAAAACCATTTTTGACGTCCTACAGTTTAAAAATTCACGAACGAGTGCATACGAAACAAAAGCCATTTGTTTGCACTAAGGACGAATGCCAAAAAGCTTTCAACACTGTCTACAGGCTACGAGCTCATCAACGTTTGCACACCGGTGATACTTTCGACTGCATGCAAACAGGTTGTGGCAAGTGTTTTACGACTTTTAGTGACTTAAAGAAACATTACAGGACCCACACTCAAGAACGACCGTACAAATGCGTGGAAGAAGGTTGCGGTCGTGCGTTTACGGCCAGCCATCATTTAAAAACTCACAAGCGAACGCATTCGGCTGACAAATTATACTCGTGCGATCGACCGCATTGCAATAAGACTTTTCCCGGAAAGGCCAGTCTCAAGACGCATCAACGGAGTCACGATATTTGGGACGAGTCTGAGACACTGTCAGATTTTGCTGACGACTTACTGCAGCATTTTGATAGTGAAACCAATAGCACGACtaacgaatttttaaaatatcaaaGCCAATTAGTCATACCACTGTCGAAAGCCAACATCGAAGCGCTAAAACGATCCGAAACGGCCGAGGTCGAGATCGAAGCATATCTGTCGGGCAGCGCCATTCAGACGTTCACGGCAGTCGGTGCGGATTCGACCACGGCCACGGTGCAGAAAATGATACTGGCCGAGCCGAACGACGACATGCCGGCCAAACTGTCGGTGGAGTGCAACATCGACGTGCAGAAGGTCGGACAGGATGCGAACGGTACGATCAGCTTGTGCGTGATGGACAACGGCGAGGTGATGTCCAGCCTGCTAATGATGCCGGTGATCAACGGGGCCAGCAGCTATGAAGCGGTGACGGAGGACGACTTCAGCCAGCCGCCGGCCATGTCGATAGCCACGGAGACGGTGCAGGAACTGCAGTTCGTCGACGAACCGGTCCGGCAGACGGTGACGGCCGTCGAACAGTCGGTAGCCGGACcggccgcggccgcggccgccGGAGCGGTCGAGCTGATACCGTTCCACGACATTCTCGTGTCCAAGCCGGACACGGACTTCGCGGTGTGCGAACCGGATCACGCGGTCGCGGAGGAACCGCTGCTTCACGTGGCTGAGGAGTTCAGCGTCGAGAAGCTCATACTCAGCCTGGCCGACGACGCGGACCGCTGCCCCGACAGCTCGGTGGCCTCGCTGATGGTCAGCCCTCAGCTGGAAGTGTTCGAGCCCGCGTTCCCGGCGCCCGTATCATCGATGGCCGCCGACGCCGACAGCGGAACCGGTTCCGGCGGCGTCGATCACGGTACCTCCGCCGGCCACCCACCGGTTACGTCCTGTTCACTGACCGTGGCCTGCAACACCCGCAAGCAGCTAAGGAAGGTGCTTGAACACAGGCGGCCAGCGAGCATATCGCATTGA
Protein Sequence: MEQPVVALVYNDLDLQHEPTPPPQQQQRPRTTEEDDGGEDGTNAYCNAGYSFVHYDFQTNSYAQYDVNPQNDGTSQEGFHDDLSQSSLSNDIPPDQSDTKRHNCEFTGCKRTYSTVGNLRTHMKTHKGEYRFKCNIMDCGKPFLTSYSLKIHERVHTKQKPFVCTKDECQKAFNTVYRLRAHQRLHTGDTFDCMQTGCGKCFTTFSDLKKHYRTHTQERPYKCVEEGCGRAFTASHHLKTHKRTHSADKLYSCDRPHCNKTFPGKASLKTHQRSHDIWDESETLSDFADDLLQHFDSETNSTTNEFLKYQSQLVIPLSKANIEALKRSETAEVEIEAYLSGSAIQTFTAVGADSTTATVQKMILAEPNDDMPAKLSVECNIDVQKVGQDANGTISLCVMDNGEVMSSLLMMPVINGASSYEAVTEDDFSQPPAMSIATETVQELQFVDEPVRQTVTAVEQSVAGPAAAAAAGAVELIPFHDILVSKPDTDFAVCEPDHAVAEEPLLHVAEEFSVEKLILSLADDADRCPDSSVASLMVSPQLEVFEPAFPAPVSSMAADADSGTGSGGVDHGTSAGHPPVTSCSLTVACNTRKQLRKVLEHRRPASISH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00469149;
90% Identity: iTF_01347500;
80% Identity: -