Basic Information

Insect: Sipha flava
Gene Symbol: ham_1
Assembly: GCA_003268045.1
Location: NW:1161318-1260429[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.3 26 5.0 0.9 3 23 266 287 265 288 0.88

2 9 0.67 58 3.9 0.1 3 23 296 317 294 317 0.92

3 9 3.8e-09 3.3e-07 29.9 0.9 1 23 321 344 321 344 0.98

4 9 3.5e-06 0.0003 20.6 2.5 1 23 350 372 350 372 0.95

5 9 2e-05 0.0017 18.2 5.0 1 23 378 400 378 400 0.99

6 9 0.0019 0.17 12.0 0.9 2 21 408 427 407 428 0.95

7 9 2.7e-09 2.4e-07 30.4 0.5 1 23 887 909 887 909 0.98

8 9 1.7e-06 0.00015 21.6 1.9 1 23 915 938 915 938 0.97

9 9 3.7e-06 0.00033 20.5 2.5 1 23 944 966 944 966 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.3	26	5.0	0.9	3	23	266	287	265	288	0.88
2	9	0.67	58	3.9	0.1	3	23	296	317	294	317	0.92
3	9	3.8e-09	3.3e-07	29.9	0.9	1	23	321	344	321	344	0.98
4	9	3.5e-06	0.0003	20.6	2.5	1	23	350	372	350	372	0.95
5	9	2e-05	0.0017	18.2	5.0	1	23	378	400	378	400	0.99
6	9	0.0019	0.17	12.0	0.9	2	21	408	427	407	428	0.95
7	9	2.7e-09	2.4e-07	30.4	0.5	1	23	887	909	887	909	0.98
8	9	1.7e-06	0.00015	21.6	1.9	1	23	915	938	915	938	0.97
9	9	3.7e-06	0.00033	20.5	2.5	1	23	944	966	944	966	0.98

Sequence Information

Coding Sequence: ATGAGGTCGAAATCGGTAGCCAGGCGTCTCGCTAAAGGCAGTAGCGACGATGGAGGTGGCGGTGGTGGCGATACAGACGCGGGTCGGAGCGACGACGAGCGTTCGTTGTCCAGCGACAGTAGTGGCGGAGGCGTTGGCAACAGGAGCCGGAGCAGGAGCAGGAGTAGCAGCATAATCAGCAACGGCGACAACAACAATGGCAAAAAGGAATCGGTGACGGCCAACGACGGCGACGGTGGCATCATCAGCCCGAGCGGTATGAACGCCGGCTTCAACTTTTTCGAGTCCCCTGCCAACGCGGCCGCCATGCCGTACAACTTGGAAGTGCGCAATGCCGGTGCTGGTGGAGTGTGGACCAAGACCCAACTCCCTAAGGGCGTCAAGTACGGACCGTTTCTAGGCAAGTGGGGACCGAAGCCTGTGGACTCGCGGTTCGCCTGGGAGGTCCGTGTTGCTGGATACTCGGGATATTTGGACGGCACGATCGAAATTTATAACTGGCTGAAATTCATCCGGTCGACCAACGACAGCAGTAGACAAAACGTTCGGGCGTTTTTACTGGCCGGTCAGATATTTTACGAATTAACACACACGGTCAGAGCTTCCGAAGAACTACTATTGGGCAAGAGAGAGCCGTTAAACTTAGATGCGGCATTCGGAGAACTAATGGCCACGTCAGAGGATCGAAGTGAAAGGGATTCAGTCGTCGCGTCGCAGAACTCGTTGGGTTCCATCGACGGGGACGGGGACGTGGACGTGGATGCCGAGGAACCGGACGAGGACGACCAAAACCGATGTATCCAGTGCGAGAAGTGCTTCCCCGACATTGAACAGTTGGACGATCACTTGGTGTCCGGGCATCACTACAAGGCCAACCAGTACGGGTGCGAGTTGTGCCCGCAAGCGTACAGCTGGAAACCGTGTCTGATCAGGCACTTGGCGCTCGCGCACAGCCGGAAGTTCACGTGCGAGACGTGCTCGAAGGTGTTCAGCGACCCCAGTAACCTGCAGAGGCACATCAGGACCAACCACGCGGGGGCCCGGTCGCACGCGTGCTCCGAATGCGGCAAGACGTTCGCCACGTCCAGCGGGCTCAAGCAGCACACGCACATCCACTCCAGCGTGAAACCGTTCCAGTGCGAGGTCTGCTTCAAGGCCTACACTCAGTTCTCGAACCTGTGCCGTCACAAGAGGATGCACGCCGACTGCCGCATGCAAGTCAAGTGCGATCGTTGCGACCAGTCGTTCAGCACGGGCACGTCGTTGTCCAAACACAAGCGGTTCTGTGAGTCCAACTCGTTGCCCACGTCCAGCAGTTGCGGCGCGCCCGTCGCGCCGAACATGTCGCAGcagcaccaccaccaccagcagcagcagcagcagcagcagcagcagcagcaatcGTCACCGTTCTCCGTGTACCCCAGGTTCCACCCGTACCCACCGCATCCGCTCGTCCACCCGCTATACTTCCCGCCAGCCAACGGGTCGCTGCCGCTGCCGCTGTTCCACGGGCCGTTCGCCGCGCTCGGCCAGTTCGTGCCCAAGCTGAACATGGACATGCTGTCCATGTCCGCCGGTGGCGGTAGCATGTACGAGATGAACCGGCACAAGCAGGCCGGTGATTCAGAGGAGCACAACGAGACGCCGGCCAAGAAGACGTCGACGGACGCGGACCGCGGCGCGTTGCAGAAGACGCCGCCGTCGTCCGTGCCGATGGGCTCGAGCAAGACGTCGCCGCTGGTCGGCGAGGAGGCGTCGTCCAACCAGCGGCCGTCGCCGGCCCGGCCCAACGTGACCACGTACCCCGACCCGAAGGTGATCAAGCACGAGCGGCCGGCCGCGGACGGCGAGTGCACCGGGCCGTGCGACCTGTCCGTCGGCACGGACATCGGCGTCAAGGAGCGCGCCGCCGACGAGGACACCGGGGACAACGGCAGCAGCAGCCCGAAGCGTCGGCGGGCGCATACGCCCGCGGCCGCGGCGGACAGGTGCGATCAGCCGCTGGACCTATCGGTGACGTGCAAGGACGAGCGCTGGAAATGCCCGCCCGCCAACGGCACCGGTGCCGACGCCGAGCCGACGGTACCCCGGTTCACGGACAGCCCACCGCTGCTTCCGCCGCcgctgtcgtcgtcgtcgtcgtcattcAAAGAGGACCCGCCGTCCGGTCGGGAGTCGCGCCGCAAGTGGTCTTCGCCGTCCGCGCTGCCACCGCCGTCCTCGCCGTACTCGGTCAGCAACCTGATGGCGCAGCCTAAGCCGCTGTACCTGGACTCGATGTACTCGGCCGCGACACTGTCCAACTTCGCGGCGGCCACGGCCGACGGCCAAGGGCTCATGCAGACGCACCAGACGTTCGGCCAAGCAGCAGCGGCGGCCGCAGCGGCTgccgcggccgcggccgctGCGTCCCGACCGTTCTCGTTCATGATGTCCAACCCGTCGCCGGCCATCGAACACTTTCTGCGGCACTCCTCGCCCATGCCCAACTACCCGAAAGCGTACCAAGACATGATGCACCAGCAGCATCAGCACcagcagcaccagcagcagcagcagcaccagcaccaccagcagcagcagcagcagcagcaccaccaccatcagcagcagcagcagacgGGCGGAGGCGGCGCGGTCAAGTCCAAGGACCGGTACGCGTGCAAATACTGCGGCAAAGTGTTCCCGCGCAGCGCCAACCTGACGCGGCACGTGCGCACGCACACGGGCGAACAGCCGTACCGGTGCGCGCACTGCGAACGCTCGTTCAGCATCTCGTCCAACTTGCAGCGGCACGTGCGCAACATACACCGGCAGGAGCGAAACTTCAAGTGCGGCCTGTGCAACCGGCGGTTCTCGCAGCAGACCAACCTGGACCGGCACGTGAAGAAGCACGAGGCGGACGACGGTACCGCGGTGGGCACGGTCACCAGCAGCTCGGCCAGCAGCGTGGACGAGAAGGAGGACCCTCGGCTGTTCGAGATCCGCAGCTTCATGAAGAAGGTGACGGACACGTCGGCCGCCTCGGCCGCCGTGGCCGCTGCGGCCGAGATGCGCAACAATAACATCGACCCTTGTCTGCCAGACGACGGGTTGTACGCGGCCGCGCACTTATGA
Protein Sequence: MRSKSVARRLAKGSSDDGGGGGGDTDAGRSDDERSLSSDSSGGGVGNRSRSRSRSSSIISNGDNNNGKKESVTANDGDGGIISPSGMNAGFNFFESPANAAAMPYNLEVRNAGAGGVWTKTQLPKGVKYGPFLGKWGPKPVDSRFAWEVRVAGYSGYLDGTIEIYNWLKFIRSTNDSSRQNVRAFLLAGQIFYELTHTVRASEELLLGKREPLNLDAAFGELMATSEDRSERDSVVASQNSLGSIDGDGDVDVDAEEPDEDDQNRCIQCEKCFPDIEQLDDHLVSGHHYKANQYGCELCPQAYSWKPCLIRHLALAHSRKFTCETCSKVFSDPSNLQRHIRTNHAGARSHACSECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQVKCDRCDQSFSTGTSLSKHKRFCESNSLPTSSSCGAPVAPNMSQQHHHHQQQQQQQQQQQQSSPFSVYPRFHPYPPHPLVHPLYFPPANGSLPLPLFHGPFAALGQFVPKLNMDMLSMSAGGGSMYEMNRHKQAGDSEEHNETPAKKTSTDADRGALQKTPPSSVPMGSSKTSPLVGEEASSNQRPSPARPNVTTYPDPKVIKHERPAADGECTGPCDLSVGTDIGVKERAADEDTGDNGSSSPKRRRAHTPAAAADRCDQPLDLSVTCKDERWKCPPANGTGADAEPTVPRFTDSPPLLPPPLSSSSSSFKEDPPSGRESRRKWSSPSALPPPSSPYSVSNLMAQPKPLYLDSMYSAATLSNFAAATADGQGLMQTHQTFGQAAAAAAAAAAAAAAASRPFSFMMSNPSPAIEHFLRHSSPMPNYPKAYQDMMHQQHQHQQHQQQQQHQHHQQQQQQQHHHHQQQQQTGGGGAVKSKDRYACKYCGKVFPRSANLTRHVRTHTGEQPYRCAHCERSFSISSNLQRHVRNIHRQERNFKCGLCNRRFSQQTNLDRHVKKHEADDGTAVGTVTSSSASSVDEKEDPRLFEIRSFMKKVTDTSAASAAVAAAAEMRNNNIDPCLPDDGLYAAAHL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01170079;
90% Identity: -
80% Identity: -