Sflv012018.1
Basic Information
- Insect
- Sipha flava
- Gene Symbol
- -
- Assembly
- GCA_003268045.1
- Location
- NW:518582-523486[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00017 0.015 15.3 3.3 3 23 7 27 5 27 0.96 2 12 0.00047 0.041 13.9 2.7 2 23 31 53 31 53 0.96 3 12 0.0004 0.035 14.1 3.4 2 23 63 85 62 85 0.96 4 12 0.00099 0.086 12.9 0.3 3 23 92 114 90 114 0.91 5 12 3.6e-06 0.00032 20.5 3.5 1 23 118 140 118 140 0.98 6 12 0.0026 0.23 11.5 0.9 1 21 143 163 143 164 0.96 7 12 8.5e-05 0.0075 16.2 3.7 1 23 188 212 188 212 0.93 8 12 3.8e-05 0.0033 17.3 2.0 2 23 222 244 221 244 0.95 9 12 1.8e-05 0.0016 18.3 2.8 1 23 251 273 251 273 0.96 10 12 3.8e-06 0.00033 20.5 1.6 1 23 279 302 279 302 0.94 11 12 6e-05 0.0053 16.7 1.2 1 23 308 330 308 330 0.98 12 12 0.00042 0.037 14.0 2.0 5 23 339 358 336 358 0.91
Sequence Information
- Coding Sequence
- atgCCTGAAAACTATGGATGTGAACATTGCgagaaaacattttcaaatcgcCGACACTATGAGCTACATGTCAATGGACATCAGCGAAACAGTTGTCATGTCTGTGGTTTACCTTGCAACAGCCGTAAGACATTGGTTACTCATATGTCAACTGCACATGGATCGAAATTAGAACCAATCATGTTAGAATGCAAGTACTGTATGAAAACATTTGTTCAAAAACGTTCATTGCACTTACATTACAAGACCATACACAAAGACACTGGTACTATATGTCTTGATTGTGGACAACCATTTGATAATAGGCTAGAGCTTGCACACCATGTAAAAACAGTCAAGCACAGTGATGGCTTTATATGTCATAAGTGTGGTGAAGTATTCACTCGAAATCAACAATACAAATTGCATTTACAAAAACATGACACTTATAGTTGTTTCAATTGCAATGCCCAGTacgcaaattctaaaaaattaaataaacatttaaaactgtGTGTTTCTTCAACACCTCCAattgacatttatttaaaaagtaaagaGGCAACTACTACAGGTATTGTTTATAAATGCATTGAGTGCAAAAAAACATTTGAGaagaaaaaatacttcaaacgACACATGAAAACAGTTGTTCATTCAGCCAACAAAGTCAGCAATCCATTATATTGTGCTCATTGtccaaagatattttattataaatttaatttgtcatcGCATatgaaacaaatacattttaaacaatacaataattatatttgtaatttgtgtGGAAAGAGTTTTCAGTATAGAAACAATTATAAAAGACACAAAGATTCTCATATGCAAGTTAGAGATTATGTTTGTGAACACTGTGGTGCttgtttttatcgtaaatatgcTTTACAAGATCATCAAATTGCCATTCATAGTGAAGAAAAGAATTTTGTCTGCAACGAGTgtggtaataattttaaattaaaatctatattaacaAGGCATATGAAAAACCATTTGGaaaccaaaaaatatgtttgtcaCTGTAAACGGGTATTTAAATTTGCATCAAATTTACGACGTCATCAAGTCAATATCCATAATCAAGTATACAGTGAGTCTATTAAAATCAAACGTTTTGTAGAAGACGATAGTCGTTCATCACCTTTAGCTGTCATAAACGAAGAAAAGAAAagattgaaacaaaaaaatattagtcaaCTTGGTCTGGAAGATACGGTTTCATATTCTATGATGGCGTATTCTGATAATTTAGATTTGAGTAGTGCTGACGTAGCAGAAAGTGTACTTCAAGTAGCTTCAGCATCAAGTTACAAGATAGAATGCgaagaaaattcatgttttccTGGGATTCATCCTCCAATTGAAACATCTCTTGTCTGCAGCTTAAATGATGGTGTTGATCTGTCTCCTAATTCTTCACAGCAATATTTATCCGATTATGTTGTTCCCCACCAGTTTCCATTTCTTaacatttaa
- Protein Sequence
- MPENYGCEHCEKTFSNRRHYELHVNGHQRNSCHVCGLPCNSRKTLVTHMSTAHGSKLEPIMLECKYCMKTFVQKRSLHLHYKTIHKDTGTICLDCGQPFDNRLELAHHVKTVKHSDGFICHKCGEVFTRNQQYKLHLQKHDTYSCFNCNAQYANSKKLNKHLKLCVSSTPPIDIYLKSKEATTTGIVYKCIECKKTFEKKKYFKRHMKTVVHSANKVSNPLYCAHCPKIFYYKFNLSSHMKQIHFKQYNNYICNLCGKSFQYRNNYKRHKDSHMQVRDYVCEHCGACFYRKYALQDHQIAIHSEEKNFVCNECGNNFKLKSILTRHMKNHLETKKYVCHCKRVFKFASNLRRHQVNIHNQVYSESIKIKRFVEDDSRSSPLAVINEEKKRLKQKNISQLGLEDTVSYSMMAYSDNLDLSSADVAESVLQVASASSYKIECEENSCFPGIHPPIETSLVCSLNDGVDLSPNSSQQYLSDYVVPHQFPFLNI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01434347;
- 90% Identity
- iTF_01347460;
- 80% Identity
- -