Basic Information

Gene Symbol
-
Assembly
GCA_036346155.1
Location
JARFIY010000362.1:780332-781839[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 2.9 8.4e+02 3.0 0.0 8 23 84 99 83 99 0.86
2 13 0.072 21 8.1 0.1 1 23 105 127 105 127 0.96
3 13 6.3e-05 0.018 17.7 0.5 1 23 132 154 132 154 0.99
4 13 0.6 1.7e+02 5.2 3.8 1 23 156 178 156 178 0.97
5 13 0.00027 0.077 15.7 5.7 1 23 183 205 183 205 0.99
6 13 0.032 9.2 9.2 3.1 1 23 211 233 211 233 0.98
7 13 0.0019 0.54 13.1 1.4 1 23 239 261 239 261 0.99
8 13 0.015 4.3 10.2 2.1 1 23 267 289 267 289 0.96
9 13 0.001 0.29 13.9 4.2 1 23 294 316 294 316 0.98
10 13 1.5 4.3e+02 3.9 3.5 1 23 322 344 322 344 0.97
11 13 1.6e-05 0.0045 19.6 0.7 1 23 350 372 350 372 0.99
12 13 0.048 14 8.6 2.0 1 23 378 401 378 401 0.96
13 13 3.5e-05 0.01 18.5 1.0 1 23 407 429 407 429 0.98

Sequence Information

Coding Sequence
ATGTCTATAATGGATAATACGCTAGTCAAAGAAGAAAAGTGTGATGCGACTCTGGAATCTTCGCACAATTATTTCAGTGGAGAGTTTCTGTTAGTTGATAAGGTTGACTTGGATGAAGCCCCAAAGTTGGAAACCGCCACGGACGAAATTTACGTGAAAGAGAAAGGTGAAAATACCTACGTCAGTTCGGATTCTGTATCCGAAAACTGCACTAGCGATGCTGAAAAACCTCAGTATTTACTGCGTGGGTACAGCAGCGCaaaaaagttcaatttggagGAACACGCGAGGATTCATGAAGAACAGGGTTTGTACGAGTGCCTTCTTTGCGACTACGAGGCGGAGAAAAAAGACCAACTTATTGAGCACTTTGAAATTCACTGTGATGAGGTTTTTAAGTGTGTGTTCTGTGGTTATGTTACTTCTCAAAAAGATTCCATCGAGAGCCACATGCTGACACATACATTTAAGTGTAGTCTTTGTGCTTATACGACCCTTTTGAAAGGGCACTTTGTGAAGCACATGAAGAAACATAGCCAAAAACCTTTTAAATGCTGGTTATGTAAGTATAGCAGCACAAGCAAGGACCATTTGAAGAACCATAAAAAGACTCATAAAGATGAGTGGCGATTTCAGTGTCTTCATTGCGTTTATAAGACTAAAGACAAACGTCGACTAACTGAACATCTAATAATGCATGGTTATGGCGAGTCTTACAAGTGCACACTTTGTGAGTTCACGAGTTGGCGGAAAGACTCTTTAAATTTGCATATGCAAACTCATGAAAATGAGCCGCGTTTTGCGTGCTCTCTTTGCAGTTATAAGACGTTCAAGCGAACGAATCTTTCATGGCATTTGAAGTCGCATGGTGAAAGACCTTTCAAATGTGCTGCTTGTAATTATAGGGCGATACACCGCTCGCATTTGAAGCGTCACATGATGTCGCATAAAGAAGAGTGGCCGTTTCAGTGCCTCCATTGCTCTTTCAAATCTAGAGAGAAGCGCAGGCTTATAGGTCACCTAAAATTGCACGGCTTTGGTGAGTTTTACAAGTGCACAGAATGTGAATTTAGCACTCCGCAGCAAGATTCCTTCAAGGCGCACATGCAGATTCATGACAGCCAGTTGCGGTTTACGTGTGCTCTTTGTAATTATAAGACTTTTACGAAAGGGCGTCTTGTATGGCACAGGAAAAAACAGCACAGcagcaagaaacttttcaaatgTGCTGTTTGTGACTATAAGGCGATAGAACAGTCTCATTTAAAGCGTCACATGATGATTCATAAAGAAGAATGGTCGTTTGAATGCTACCACTGCTCTTATAAATCTAGAGAAAGACGCAGATTTGTAGAGCATTTAAAATTCCATGGTTTTGGCGAATTTTACAAGTGTGCAAAATATGCATGA
Protein Sequence
MSIMDNTLVKEEKCDATLESSHNYFSGEFLLVDKVDLDEAPKLETATDEIYVKEKGENTYVSSDSVSENCTSDAEKPQYLLRGYSSAKKFNLEEHARIHEEQGLYECLLCDYEAEKKDQLIEHFEIHCDEVFKCVFCGYVTSQKDSIESHMLTHTFKCSLCAYTTLLKGHFVKHMKKHSQKPFKCWLCKYSSTSKDHLKNHKKTHKDEWRFQCLHCVYKTKDKRRLTEHLIMHGYGESYKCTLCEFTSWRKDSLNLHMQTHENEPRFACSLCSYKTFKRTNLSWHLKSHGERPFKCAACNYRAIHRSHLKRHMMSHKEEWPFQCLHCSFKSREKRRLIGHLKLHGFGEFYKCTECEFSTPQQDSFKAHMQIHDSQLRFTCALCNYKTFTKGRLVWHRKKQHSSKKLFKCAVCDYKAIEQSHLKRHMMIHKEEWSFECYHCSYKSRERRRFVEHLKFHGFGEFYKCAKYA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-