Basic Information

Insect: Sinelater perroti
Gene Symbol: topi
Assembly: GCA_036346155.1
Location: JARFIY010000348.1:3872487-3888054[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00084 0.24 14.2 2.1 2 21 96 115 95 116 0.94

2 14 2.2e-06 0.00064 22.3 0.9 1 23 141 163 141 163 0.97

3 14 0.0085 2.4 11.0 2.0 2 23 170 191 170 191 0.95

4 14 0.018 5.1 10.0 0.0 2 20 210 228 209 230 0.92

5 14 7.2e-05 0.021 17.5 1.5 2 23 310 331 309 331 0.97

6 14 0.031 8.8 9.2 0.3 1 22 337 358 337 358 0.94

7 14 0.095 27 7.7 2.7 2 21 374 393 373 397 0.83

8 14 0.48 1.4e+02 5.5 0.1 1 23 520 543 520 543 0.95

9 14 0.0029 0.84 12.5 0.1 1 23 547 569 547 569 0.97

10 14 3.2e-07 9e-05 24.9 2.5 1 23 575 597 575 597 0.98

11 14 0.025 7.1 9.5 0.2 1 23 603 628 603 628 0.96

12 14 0.42 1.2e+02 5.7 2.5 1 23 634 656 634 656 0.85

13 14 2e-05 0.0058 19.3 0.3 3 23 664 684 662 684 0.98

14 14 3e-06 0.00087 21.8 0.5 1 23 690 713 690 713 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00084	0.24	14.2	2.1	2	21	96	115	95	116	0.94
2	14	2.2e-06	0.00064	22.3	0.9	1	23	141	163	141	163	0.97
3	14	0.0085	2.4	11.0	2.0	2	23	170	191	170	191	0.95
4	14	0.018	5.1	10.0	0.0	2	20	210	228	209	230	0.92
5	14	7.2e-05	0.021	17.5	1.5	2	23	310	331	309	331	0.97
6	14	0.031	8.8	9.2	0.3	1	22	337	358	337	358	0.94
7	14	0.095	27	7.7	2.7	2	21	374	393	373	397	0.83
8	14	0.48	1.4e+02	5.5	0.1	1	23	520	543	520	543	0.95
9	14	0.0029	0.84	12.5	0.1	1	23	547	569	547	569	0.97
10	14	3.2e-07	9e-05	24.9	2.5	1	23	575	597	575	597	0.98
11	14	0.025	7.1	9.5	0.2	1	23	603	628	603	628	0.96
12	14	0.42	1.2e+02	5.7	2.5	1	23	634	656	634	656	0.85
13	14	2e-05	0.0058	19.3	0.3	3	23	664	684	662	684	0.98
14	14	3e-06	0.00087	21.8	0.5	1	23	690	713	690	713	0.98

Sequence Information

Coding Sequence: ATGAACAACCCCTATAACATATTTCTCACGGTGCACCGCATCGACGAGGATGGGACCACGAGCTCGTATCAGTACGAGGAGGACTACGTCACGCAGGAGTACTCCTGGAGCTGCCCTTCGGACAACAAGGTGGGCCTCAGCTACCGCTACCTGGAGCCGGACGACCAGTCGGTGACCATAATCAAGATCGGGGGAGTGGAGGACCTGAACCTCATGAACTATGCCACGGAAATAAGCACTACCCTCAGCCGCGAGAGCAGGATACTCAATATTCCCACGATGGTGAGGTGCCAGAACTGCGACACGAATTTCCCTACCAAGTACCAGTACCAGCGCCATCAGTGCGAGTTCAATGCGGATAAGGTGgTGTTAAAAGCTAATGTCGACCTAAAGGACATCGATAAGGGCATGAGAATAAAATACGACTGTGCCACCTGTGGCAAACAATTTGTTAGTAAGAACAATCTGGAGAGGCACCAGTCAAGACATGATGGCAGCCGAGAGAACGTTTGTGAGCACTGCAATAAACAGTTTGTGAGTGAAAACCGCCTCCGAATCCATAAAGAGAACCACTGTAAAAAAGCCGGAGGCATCTCCAAATTCTACCGCAGTGACGTGACTGTCTGGAAGTGCGTGAAGTGCAACCAAGTATTCGCTACTCCTGCGTCTGCAAATCGCCATGCGGAGAGCTGCACAGAGGTCCTAGAGTATATCGGCGACCCTGAAATTAAAGCCGAAGAGACGGGAAACTCTTCACAGGACTCTAACGAGATGACCATTTTAAGAGAAGAGATTAAGAAAGCGACTTCCATCGCCCCTGAAATAGTTGCCGAAGAGAACGCTTCTGCCAATGCTGATATTAGTAATCCTGTACAGGAACTTGCCGTGACCGCTAACGTTGAAAAGCTGCTGACGGAGCTTCTACTACAGTGCGAGTTTTGCAATCGTACTTACTCCGACCGCAACCTGTTGCTCCTGCATCAGAGGAAGCACACGACCGCAGCGAACTATGAATGCGTAAACTGCAAAGAAACATTTGATTCCTACACATCGGCAACAAAGCATTGGATGACAAAGTGTTCCGATGAAGCCAACCTGTTTTATTTGCCAAAAATGACCTACTGTGAATACTGCGATCGTACGTTCAAATCACACGAAATTCTTTACactcacaaaattaaaaagaagcaCTACAGCCCAAAGCCACATATCGTGGAAGAGAAGCCTCTCGAAGATTTGCAATCTTCAGACGGCTCTGACGGCAAAGAGTTGCTTGTCAAGTTCATTGAGAATGCACTTACTATGCTGGACGTTTCAAAAGCCAAACATGCGAATAGTTCTTTTAATGCaggtgataaagaaaataaggagcCCGCTAAACCCAACGAGGCCGATGAGTTTTCGGTggtacaaaagaaagaatttaaaatggacGACGCGTTGCGGGATTCAGAAAATCAAGaaccagaaaagaaaaaacgtgGGCGTAAGCGTAAGTGGCCCAAGCAAATGACGAAAGCTAAACTACCCTCTATGGTTGTTGACGAAGGTTATAAGTATCAGTGTGAGCGCTGCATTGATGTTTTCGAAAACATTTCCGAGTTGGAAACTCACCGAGAAAAGGAGCACGCTTCAAACTTTACTTGTGAAGAATGTGGGcagGTAGTACATAGTGCTAAGGCTTTGATTATTCACAGCAGGGCACATCAAAGCTTAAAACCATATGTTTGCGAACAGTGTGGTAAAAGTTACTCACAAACTTCGCATCTTTGGCAGCACATGCGATTTCATCAGGGTATTAAACCATTTGCTTGCCCTCACGAAGGATGTGAAGCTCGTTACACCATTCGACCCGATTTGAAGGACCACATCAGGAAAGTGCACACCCGTGAAAGGCCATTTAAGTGTGCCGTGTGCAACAAGTGCTTCCTGACCGGTTCGGTATATTACCAACATCGGCTCATCCATACGAACGATCGCCGATACGGATGTGATatttGTGAAAAGAGATTCTTCCGGGCTGATGCTCTGAACAATCACAGGAGAATTCATACGGACGAAAGGCCGTACCCATGCGAGATCTGCGGAAGGGAGTTCAGGCAGAAAGGGGACAGAAACAAGCACGTACGTACTCAACATCCTGAGTGA
Protein Sequence: MNNPYNIFLTVHRIDEDGTTSSYQYEEDYVTQEYSWSCPSDNKVGLSYRYLEPDDQSVTIIKIGGVEDLNLMNYATEISTTLSRESRILNIPTMVRCQNCDTNFPTKYQYQRHQCEFNADKVVLKANVDLKDIDKGMRIKYDCATCGKQFVSKNNLERHQSRHDGSRENVCEHCNKQFVSENRLRIHKENHCKKAGGISKFYRSDVTVWKCVKCNQVFATPASANRHAESCTEVLEYIGDPEIKAEETGNSSQDSNEMTILREEIKKATSIAPEIVAEENASANADISNPVQELAVTANVEKLLTELLLQCEFCNRTYSDRNLLLLHQRKHTTAANYECVNCKETFDSYTSATKHWMTKCSDEANLFYLPKMTYCEYCDRTFKSHEILYTHKIKKKHYSPKPHIVEEKPLEDLQSSDGSDGKELLVKFIENALTMLDVSKAKHANSSFNAGDKENKEPAKPNEADEFSVVQKKEFKMDDALRDSENQEPEKKKRGRKRKWPKQMTKAKLPSMVVDEGYKYQCERCIDVFENISELETHREKEHASNFTCEECGQVVHSAKALIIHSRAHQSLKPYVCEQCGKSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCNKCFLTGSVYYQHRLIHTNDRRYGCDICEKRFFRADALNNHRRIHTDERPYPCEICGREFRQKGDRNKHVRTQHPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -