Suni008679.1
Basic Information
- Insect
- Silvanus unidentatus
- Gene Symbol
- AP2S1
- Assembly
- GCA_963930825.1
- Location
- OZ005759.1:4834935-4842355[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.00012 0.011 16.3 1.0 1 23 143 165 143 165 0.98 2 8 0.015 1.5 9.6 4.2 1 21 171 191 171 195 0.88 3 8 0.28 28 5.6 0.1 2 20 329 347 328 349 0.91 4 8 6.5e-06 0.00064 20.2 4.6 1 23 894 916 894 916 0.99 5 8 1.9e-06 0.00019 21.9 4.7 1 23 922 946 922 946 0.92 6 8 7.3e-06 0.00072 20.1 0.7 2 23 1365 1386 1364 1386 0.97 7 8 0.00046 0.045 14.4 1.7 1 23 1392 1416 1392 1416 0.92 8 8 0.00067 0.066 13.9 2.8 1 23 1434 1458 1434 1458 0.93
Sequence Information
- Coding Sequence
- ATGGGAGACAGTGTTGCTTCGTATTTACACAAGAAATTCAAGAAACAATTGAGTTTAGGTGCTCCCACAACAAATCAACATGTGGAAACAACCAATCAGAATGTGGCTATCATAAGTGGATGTaatgaaaacaataataacGAAACAAAATTGGACAATAATTCGCtagaaaattataaaacagaCGTGCCAAATTCAAGTACAAATACAATTAACAAGTCTTCCATATCAGTAATAGAACAAGATGAAAATAGCCATAGTAAGAAATGCATATCGTCTACTGAACCACAAATTGGACCACATTTTGAtagaaaaattattcaaattaaatCGTCTTCCATAAATAAACTAGACGATGACACTGTGAATCAATCGCTGGATACGAAAAATGAGGAGAATTTAATACAGCGCCATCCGAATGGCAAATATGTTTGTACATATTGTAGTTTAGTATGTTCTAAACCGAGTGTATTACAGAAGCATATACGAGCACACACAAACGAACGACCATATCCATGTCAACCGTGCGGTTTTAGTTTTAAAACGCGTTCCAATCTTTACAAACATTGCCGTTCACGTACACATGCCAATCGAGTCATGGGCACCACACAAAGAGAACCCGAACAGGGCAGCGGTGTTTCAGTACAACCGCAAAATGCCAACGAATCCAAACCGTCAATACACAAACCATACAAGCCCAGATTTCACACGAAATCCCTCTTCGAAACCAACACAAAGGAGAATTTGGAGCAAATCGAACCGCCACCACCCTCGTCGCACCACTCGAATGACTTACTAACACATCACATTAACGAAATCATTAACAAGAACAACACAATCGTGAACAGTAGTGCAGGCAGTGATGAACCGTTGAATTTGACCAATAAACGGAAACGATGTATGAGTGAAGTGCAAACCGAACCACTTATCGGTAATAAGAGTTTAATTAAAGAGCTTTTATTGAAAAACTTAAACTCGGACATGGAATGTCAATATTGCAAGATGATATTCCAAACTGTAACCGAATTGGAATTGCACAAATTACGTAGTTGTAAAGGGAAACCTTTGGGGGGATTGAAATATACACGCAGTAGTTCCGTTAATGTTGCATCGATTTTAACCCAAAATAAGAACGCTTTTGATAATATACcacaatttcaaaatgttgCCTTTCCATTAAGTTCACCCGGTCCGTTTTTAGGCAAAACGAGACTAGTTGAATCGGATAAAACGAAATCGTTTTCATTTGACGGTCTATCGTCCACTTCTTCACCGCTACTCTCACCTTTTGATAAAGAGAAACGGCAACCAGTCAAATTGTTTGGTGGCGAAGTGAAAATTACACCATCAACATCGACACAAGAATCGAAACAGTTTCCTGTCAAATTGCCCACGGATTCTTCTGCCAGTGTAGACTTGAGGGAGAATCGGGTGATAAAATCGGGATTACATTCCGGTGGTACAGTGTTAACGaataaaacagttaaagaGGGCCAACAGACGGATGTGATCCGAGTGTATGAAAGTACATCAGTCTCGCCAACAATTAACATGCAACATTTAACGAAAAAGCAGCattttaattttgatttgaatAGTGCATCGAATATAATTGATTTCAGTCAAAATGCTTTGAAATTATTAACaccaaatttaaaacaacCGAGTCCATTGGATTTGATACGGTCAATGCCACCGGTCATGACTACATCTTTGAAAAATGAACCGAGCCCGGATAATACGGAGCCGATTTCAATGGACGTTGATTCGAATGTCGCCCAAAATCTGTCCAATAATGTGGACATGGATGTGAAGGCATCCAAGATGCCTGTTgtacaaaagaaaattaattgtGATTCTGGTTATACGAATTTAAAGCATTTTATTGTCGATGGAAAGGTTGTTAGGCATGTACCTGGAATTCCTGGTCCAGTCACTCCTGAAGAGCCAATGGATATGATTCAAgtaccaccaccaccaccgccacgAAAACCGTTGACCAGTCCAGAAAAATCGAAATCCTATCCTCCAAATGAAGAATCGTTAAAAATTCCGAAGAAAATCGATTCCGTAGAAGTGAAAACCGAACCGAAATCACCAATCAAGGCGCCTTTAACGCCATCAGGTGGCAATCGTGAATCAACGCCACCGAAACCGTCATTGCTGACGAAAAAATTCGCACGACCAAATAGTTTAGCACTGAAACCGACCACAGCATCATTGAAACAGCACCATGGTCTGACGCCAACAATGTTTAATCAGATATTAATCAGTCCTGATACGCCGCGAGTGGCAAAGAAATACGCACAACACTTTTTACATGGGAATTATTTCAGTTATTTGGGATTGAAGAGCAGTACAAAACCGACATATTGTACATTGAATAAAACGCAACCGTTTTATGTGCCGCATTTTAAGAAATTAAGTATGTACAGTGAATGGAGACAACAGGATACGAAAACGGAAAAGATTTATGCGAGTCAGTATGATTCGAGACAAAGATCAGGACGGTATTGTATGGCGGGAAAGACGGAAGCGGATTTAATTATACATTCAAGTTATAAGTTTATTGTGTCGGACAAGGCTGATACATCGGATGATCAGAAATCCACCCCAATACCGGGCGGATATGAAAGTTACGAAGACTATACGTATATACGTGGAAGAGgcCGAGGACGATATGTGTGCCATCAGTGTGGGATCCGATGCAAAAAGCCGTCAATGTTAAAGAAGCATATAAGAACACACTCGAATGATCGCCCATACACCTGCAGTCATTGCAATTTCAGTTTCAAAACGAAAGGAAATTTAACCAAGCACATGAAAAGTAAAGCGCACACAAAGAATTACGCGGCAAATAGTTCAGGTAGTGGAAATATCAGTTCAAGTTCGAGTTCTACACAGTTGAGTGGCACTCAAAGTTCCGATTCGGACACAGAAGACAGCGGAATGGATAGTAGTGATGAGAGTACGCGACAACAAGAGCATGAAGCAGCGTATGGTTTATTGTCATTGTCACAAAAAACGAATCCGGCCACATCCAGTCCTATTCCACCGTCGCCCGGTCAAGCGAACGATGTTGTCATGTCACCACAAACGGACGTTCTGATGAGTACTGAAGAGATTGCACATGTAACAAAACGAAATTAcgcaaaaaataaaataatggacgatagATCGCCAATGAATTTCAATGTAATACATTTAAATAATGAATTGACGGTGAATAATGAATCGGATTCAGTGGATAAGACGAATTTAATGCAATTCTTGGGGAAAACAAATCTAACACGACCGCTCACATATCCATATACGTCTGTGTTGAGTGATGTGAGTAGTAAGAACGGGAATCAAACAACGAAAGAAGATGAGGACAGTGAGAAGAGTATAAAACAGTTTCATGTGATACAGAAGTACGCATTGGAGGCACCGCAAACAGTGAATTTGGTGAAAGAGATGAAGAGTTTTGATACCAGTTCAAATAACAGTCGAATGGTGATTGTAAAGAATCATTCACCACCTACTTTGAAGGTGAATGGAGTGGTGGTGAATGAGACGTTGCAGCAGGAAGTGCGAAAACGGAAGAGTAACATTTTCGATGGGATTGGAAGTCATAAAATGCAGAGAAATGGTTCTGCACAGAATGAGGATGAAGTGATGGATTTATCAACCGAGAAATGTGAAGAGTCGATGGACACACGATCGGAACACAAAAATCCAATTGTGCCGAGTAGAAAAATGgtgattttgaattattttgaAGATACAAATAAATCAACGCCAATAAGTGTTAATTATGTGACGGAGAATGCTGGAAGTAATAACAATTCAAATGCGAAACCGATGGATGTTGTTCATAAACCGTTAGCGCCACTTCCACCACCGCAACAATACGAGTATGATAATAGTGCAATGGAAACATTGGCGGATATTGCAGTGAAACAGGTGAAATTGGAGAAAGATACGTTGGCGAAGAGTTTGGCATCGGAATACCTGAAATTGGCAACGAATAATTACAATTCACCACCATCACCGCATCATACGAACAGTAAAGATGTGAATGAGTTTCTTGTTAAGCCCGAGGGAAATAAAAGTTGTACGATTTGTGCGAAGAGTTTCAATAAGCCGTCTCAATTGAGGTTGCATATGAATGTGCATTATTTGGAGCGGCCGTTCCGATGTGACTCGTGTGCTGTTAGTTTTCGAACCAAGGGACATTTGCAGAAACATGAACGAAGTGCAAGTCATCACAACAAGTTGTCTACGTCGCCTGCATTATCGTCATCAGAACCGCGTCCATTTAAATGTACGGAATGTAATATAGCGTTTCGTATACATGGTCATTTAGCGAAACATTTACGTTCTAAAATGCATATAATGAAATTGGAATGTTTAGCGAAAATTCCTTTCGGTTTGTATGCAGAATTGGAAAGGTCAAATAGTTTAACTGAAATAAATACGTGCGATGGGGACCAATGTTTAGAGAGCCTAAAGacATTAGCGAAAAAAGTTTTCATAAATACGGAAATTCGTTTCATCCTGATTCAGAATCGGGCTGGAAAGACCCGTTTGGCTAAATGGTATATGAATTTTGATGATGATGAAAAACAGAAGTTAATTGAGGAAGTCCATGCTGTTGTAACTGTTCGTGATGCAAAGCACACCAATTTTGTTGAGTTTCGAAACTTCAAAATCGTTTATAGAAGATATGCTGGCTTGTATTTTTGCATTTGTGTTGATGTAAACGACAATAACTTGTGTTATTTGGAAGCGATACACAATTTTGTGGAAGTGTTAAACGAATACTTCCATAACGTTTGCGAATTAGATCTGgtgtttaatttttacaaaGTGTATACTGTTGTTGATGAAATGTTTTTAGCTGGAGAAATACGCGAAACTTCACAGACAAaagttttaaaacaattactGATGTTGAACTCCTTAGAATGA
- Protein Sequence
- MGDSVASYLHKKFKKQLSLGAPTTNQHVETTNQNVAIISGCNENNNNETKLDNNSLENYKTDVPNSSTNTINKSSISVIEQDENSHSKKCISSTEPQIGPHFDRKIIQIKSSSINKLDDDTVNQSLDTKNEENLIQRHPNGKYVCTYCSLVCSKPSVLQKHIRAHTNERPYPCQPCGFSFKTRSNLYKHCRSRTHANRVMGTTQREPEQGSGVSVQPQNANESKPSIHKPYKPRFHTKSLFETNTKENLEQIEPPPPSSHHSNDLLTHHINEIINKNNTIVNSSAGSDEPLNLTNKRKRCMSEVQTEPLIGNKSLIKELLLKNLNSDMECQYCKMIFQTVTELELHKLRSCKGKPLGGLKYTRSSSVNVASILTQNKNAFDNIPQFQNVAFPLSSPGPFLGKTRLVESDKTKSFSFDGLSSTSSPLLSPFDKEKRQPVKLFGGEVKITPSTSTQESKQFPVKLPTDSSASVDLRENRVIKSGLHSGGTVLTNKTVKEGQQTDVIRVYESTSVSPTINMQHLTKKQHFNFDLNSASNIIDFSQNALKLLTPNLKQPSPLDLIRSMPPVMTTSLKNEPSPDNTEPISMDVDSNVAQNLSNNVDMDVKASKMPVVQKKINCDSGYTNLKHFIVDGKVVRHVPGIPGPVTPEEPMDMIQVPPPPPPRKPLTSPEKSKSYPPNEESLKIPKKIDSVEVKTEPKSPIKAPLTPSGGNRESTPPKPSLLTKKFARPNSLALKPTTASLKQHHGLTPTMFNQILISPDTPRVAKKYAQHFLHGNYFSYLGLKSSTKPTYCTLNKTQPFYVPHFKKLSMYSEWRQQDTKTEKIYASQYDSRQRSGRYCMAGKTEADLIIHSSYKFIVSDKADTSDDQKSTPIPGGYESYEDYTYIRGRGRGRYVCHQCGIRCKKPSMLKKHIRTHSNDRPYTCSHCNFSFKTKGNLTKHMKSKAHTKNYAANSSGSGNISSSSSSTQLSGTQSSDSDTEDSGMDSSDESTRQQEHEAAYGLLSLSQKTNPATSSPIPPSPGQANDVVMSPQTDVLMSTEEIAHVTKRNYAKNKIMDDRSPMNFNVIHLNNELTVNNESDSVDKTNLMQFLGKTNLTRPLTYPYTSVLSDVSSKNGNQTTKEDEDSEKSIKQFHVIQKYALEAPQTVNLVKEMKSFDTSSNNSRMVIVKNHSPPTLKVNGVVVNETLQQEVRKRKSNIFDGIGSHKMQRNGSAQNEDEVMDLSTEKCEESMDTRSEHKNPIVPSRKMVILNYFEDTNKSTPISVNYVTENAGSNNNSNAKPMDVVHKPLAPLPPPQQYEYDNSAMETLADIAVKQVKLEKDTLAKSLASEYLKLATNNYNSPPSPHHTNSKDVNEFLVKPEGNKSCTICAKSFNKPSQLRLHMNVHYLERPFRCDSCAVSFRTKGHLQKHERSASHHNKLSTSPALSSSEPRPFKCTECNIAFRIHGHLAKHLRSKMHIMKLECLAKIPFGLYAELERSNSLTEINTCDGDQCLESLKTLAKKVFINTEIRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLNSLE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -