Basic Information

Gene Symbol
-
Assembly
GCA_963930825.1
Location
OZ005758.1:23920721-23923600[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 6.9e-05 0.0069 17.0 1.8 2 20 104 122 103 123 0.94
2 13 0.00013 0.013 16.1 5.1 2 23 262 283 261 283 0.96
3 13 0.00011 0.011 16.3 0.5 1 23 289 311 289 311 0.99
4 13 0.00045 0.044 14.4 7.5 1 23 317 339 317 339 0.96
5 13 0.00075 0.074 13.7 1.2 1 23 343 366 343 366 0.95
6 13 0.00042 0.042 14.5 0.7 3 23 374 395 372 395 0.94
7 13 0.00042 0.042 14.5 1.5 1 23 401 424 401 424 0.97
8 13 6.9e-06 0.00068 20.1 0.8 1 23 430 452 430 452 0.97
9 13 7.2e-06 0.00071 20.1 1.8 1 23 458 481 458 481 0.97
10 13 8.9e-06 0.00089 19.8 0.1 1 23 489 512 489 512 0.96
11 13 3.7e-05 0.0037 17.8 2.9 1 23 520 542 520 542 0.97
12 13 1.5e-05 0.0015 19.1 0.8 1 23 548 570 548 570 0.99
13 13 2e-05 0.002 18.7 0.9 1 23 576 599 576 599 0.97

Sequence Information

Coding Sequence
ATGCAAGAGCTTTGTGGCTACCAAATTCCAtttAGTGAATCGGATGTTTTGTGTTCTGTTTGCAGTGATTCTCTTAGTTTAAATGGTGAATTTTTATCATCCTGTCAAGAAGCTCTTGCTTTTTGGACAGTTTTCGTTCTAAAACAACAAGAACCAAACAATAAAGATATAAATTTCGGCCAATTTGAAGCCCTACAATCAAACATAGATTTAGATGAAGTGGAACCAAAAGGAGAGCCTGCGGATGAACCTGAGGACATAAACTTGATAGAGAATTCAACTTCAAATGCTCCTTCACGTCATCCACTTACATGTCACATCTGCCAAAAGACGTTCACAATGCCATCACGATTAAAACGGCATCATaTTCCTGAAGAGAAATGCTTACCAAACAAATTGTGCTTCAATTGCGTTGCTGATTTAACCGATTTATACGAGTTCCGAGAGATTTGTTCATTTATATTCCAAATTGATTTCAAACAAGCTTCAAAAACTTCTTGTCGACTGTGTGGAAATCAATCGGCAGACACTCCTCTGACCAGAAGAGACAGTCGTTTTTTACGGGAATTATTTGCTTACAAAATACGTATCTATAAGAATGGAGCGATGGTCTGCACAAAATGTTCAGATTCCCTCGTATTCAACTCCCTTTTCTATTCAAGTTCTAAACAGGCATTCAAGTCTTGGATGGAATTTGTTTTGCAACAACCAGAAGACAGTATTTTCAACCCTTCTACCTTTAACAAATCTCAACTGAGCCCTGAAGAGTTGGATTCTTCGTGTCAATGCAATTTGTGCTCAAAAACATTTGCGACAAAGGAAAAATTGGAAGTTCATTTAAAACACCATTTAGAAGTGGGAATGTTCAAGTGTGAAATTTGTTCGAGAATCTTAAATTCCAGAATAACATTAAAATCGCATATGGCAACACACGGGGATATTGAATATTTCTCTTGTAACAAATGTCCAAAAATTTTTAGGCACAAATATTGTTTTAGACGTCATGTTGAGAATCATTCAAAAGAATTTACTTGTCCAAGGTGTTTTAAACCATCCCGTTCTAAATTTTCTttgaagaaccatttaatttTGGAACATTATCCCGAACGAGCGATGCATTGTTCATTATGCCCGAAGGTATTCGCTGTTAAAGATCTTTTAGATGTACACATGAAGTTTAAGCATGAGAAGAGAAGAGATTTTCAATGTGATCAATGTCCAATGGCGTTTTTTAAACACGTTGAGCTCAGAAATCATGTAAAGAAAGTGCATTTGAATGAGAATTTGTATACTTGTAGTGTTTGTTCAAAGAATTTTGGTAGGAAAGAGTCTTTACGGAACCATATAGTATCGCATAGCACTGAAAGACCGTTTAAATGTGAACTGTGTTCATTCACATTTAAACGTTTGAAATCATTGAGAGCGCATATGAATAATGTCCATCCAAAAAAGGAAACGCAAAAATTTCCCTGTGAAATTTGTGGTAAAGctttaaaagtaaaaaaatctCTTGAAAGACATATTCTGATCAAACATACGATGAAAGATTTGAAACCGTTTAAATGTGATATTTGTTTACGGAGCTTTAAAACTGCTAAATATTTAAAGAAGCATTCGCAGAATCATCTCGAAGTGAAACCTTATCAGTGTGATACATGTTCAAAGACATTTGCAAGTAAAGGGATACTAAGAGTTCATATGAACAAGCATTCCAAAGTTAAACCATTTAGTTGTAATTTATGTGATATGAGATTTACTCAGAGTCAAAGTGTTACACGTCATTTAAAAGTTGTTCACTTTGTTGAAAGttaa
Protein Sequence
MQELCGYQIPFSESDVLCSVCSDSLSLNGEFLSSCQEALAFWTVFVLKQQEPNNKDINFGQFEALQSNIDLDEVEPKGEPADEPEDINLIENSTSNAPSRHPLTCHICQKTFTMPSRLKRHHIPEEKCLPNKLCFNCVADLTDLYEFREICSFIFQIDFKQASKTSCRLCGNQSADTPLTRRDSRFLRELFAYKIRIYKNGAMVCTKCSDSLVFNSLFYSSSKQAFKSWMEFVLQQPEDSIFNPSTFNKSQLSPEELDSSCQCNLCSKTFATKEKLEVHLKHHLEVGMFKCEICSRILNSRITLKSHMATHGDIEYFSCNKCPKIFRHKYCFRRHVENHSKEFTCPRCFKPSRSKFSLKNHLILEHYPERAMHCSLCPKVFAVKDLLDVHMKFKHEKRRDFQCDQCPMAFFKHVELRNHVKKVHLNENLYTCSVCSKNFGRKESLRNHIVSHSTERPFKCELCSFTFKRLKSLRAHMNNVHPKKETQKFPCEICGKALKVKKSLERHILIKHTMKDLKPFKCDICLRSFKTAKYLKKHSQNHLEVKPYQCDTCSKTFASKGILRVHMNKHSKVKPFSCNLCDMRFTQSQSVTRHLKVVHFVES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-