Basic Information

Insect: Sialis lutaria
Gene Symbol: PRDM10
Assembly: GCA_949319165.1
Location: OX439241.1:26094903-26102924[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0062 0.34 11.7 2.6 2 23 499 520 498 520 0.96

2 12 0.025 1.4 9.8 0.3 1 23 616 638 616 638 0.95

3 12 0.12 6.6 7.6 0.1 2 23 653 674 652 674 0.94

4 12 0.00014 0.0079 16.8 0.3 2 23 684 705 683 705 0.98

5 12 0.0012 0.063 14.0 2.6 2 23 714 735 713 735 0.97

6 12 1.2 65 4.5 0.8 1 12 742 753 742 764 0.75

7 12 0.0012 0.067 13.9 2.7 1 23 770 793 770 793 0.97

8 12 0.0002 0.011 16.4 3.6 1 23 798 820 798 820 0.98

9 12 0.00024 0.013 16.2 2.3 2 23 827 849 826 849 0.93

10 12 0.051 2.8 8.8 1.6 1 23 896 919 896 919 0.97

11 12 0.0001 0.0055 17.3 2.0 1 23 941 964 941 964 0.97

12 12 0.017 0.95 10.3 5.9 1 23 999 1022 999 1022 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0062	0.34	11.7	2.6	2	23	499	520	498	520	0.96
2	12	0.025	1.4	9.8	0.3	1	23	616	638	616	638	0.95
3	12	0.12	6.6	7.6	0.1	2	23	653	674	652	674	0.94
4	12	0.00014	0.0079	16.8	0.3	2	23	684	705	683	705	0.98
5	12	0.0012	0.063	14.0	2.6	2	23	714	735	713	735	0.97
6	12	1.2	65	4.5	0.8	1	12	742	753	742	764	0.75
7	12	0.0012	0.067	13.9	2.7	1	23	770	793	770	793	0.97
8	12	0.0002	0.011	16.4	3.6	1	23	798	820	798	820	0.98
9	12	0.00024	0.013	16.2	2.3	2	23	827	849	826	849	0.93
10	12	0.051	2.8	8.8	1.6	1	23	896	919	896	919	0.97
11	12	0.0001	0.0055	17.3	2.0	1	23	941	964	941	964	0.97
12	12	0.017	0.95	10.3	5.9	1	23	999	1022	999	1022	0.96

Sequence Information

Coding Sequence: ATGAAAGCAGTGTTGACAACACCGTTGTTTGACGAAGAAATGACTGTCTGGGCTTCCGAATGCGACGAACAGACACTCAGCACCATGCATTCTGCCGATGCATCAAACAACTCACAACTCTTGCTTATTGCCGTGGAATACGTAAATGATGAGAATATGGGCTTTGATGCACTGAACACATCAGACGGAAGTACTCTTCCTCAAGGGATATCACAACCGTTCATCTACGATGATCAAGTCAGCGCCTTGGACCCCAACATGGGCTCTACGGCTCAGTATTCTCCTGTCTACACTTCAGACAGTACGCAGTACAACCAAAACCCCATCGTACTGCTTCCTAAGACATCGGATGGGAACGATAACATCTCGTTACCCGTAGACGGAATGTATTTTTTAAGACAGGTCGTTTCAAGTCGTCTAAACCAACAGCCAAGTCTGCAGAAAAGCAATATGAAGCGTGAATCGGAATCAGTCGAGTTCCTTATAACTGATCAGAATGGGATTTCGTATACTCGGACTCAAGAAAATCTAGCGGCAAGTCTGACAGATCAAACAGACTTGTCTGGGTTACTGAGTAGCATCGATCAGAGATTGCCCGAAGACAGACTCCTAGATGCGCAGGGTCTAGCTTTAGACTCTAATATGATAGGTCTTGATGAACTCGTACTTATGAAGTCTAATTTAACTAACGATTTACCTCAGGTCGTTCACCACATCGATATCAACATAGAGCCGAGCATAACTGACCCGTTACCGGACACTTTTAAAGAAGTTTGCAACGCAAGCGAGCTCAGTGAGATCTTGAATCAGGAGGACGAACCTCTGCAGAAGATAGATACCGATGAGTACACTGTCAAGATGGAGAGTGCAGATGCTCCGGCACGGAGACAGCCAAAGAGGCAGTTCTTTGGAAGAGACGATCTTTGTGACGATGAGATCATTGATGACGGTACAGAGTTATACACTGTAAACTGTCCGGACTGCCCTCTAGACGGAACAGACGAGCTAGTGTGTCCCCGGCATCGTGTACAGAGCATCAGCGACAAGCCTGTCCCGTCAAGAGCGCGGGCAACCCTCCCGGCGTCTTACCTGTCAATCAACAAGGTTGGCAATGATGAAAACGGAGAACCAATTCAAGGAGTGTTTGCAAGGAAGCTGATACCGAAGAGAACTCAGTTTGGGCCAATAGAAGGTGTGATGGTGCCTCTGAACATTGACAAGAAGTATAATATTGAACTCGTGCTGGAGAGCGACTCGGGGGAAATGTACAGACTTGATGTCAGCGATGAAAatATGTCCAACTGGATGAGATTTGTGAGAAAAGCAACGACTGTAAAGAATCAGAATTTGCTTTTGAATCAGATCGGTTCTTCTCTGTATTACATAACAACTTGTAATATTCTACCACGCCAAGAACTCAGGGTCGGATACAGCACTAGTTACGCAGATAAGAGAGAATTAAAGCTTCTAGAACGTGAGGTGACTTCGGTTTGGTCTTGTTTTGAGTGTACGATGACGTTTACACTTTATAAAGATTTGCAGAAACATTTATGTATACATGATAAGAATGATGATAAGAAATTAAAGTCAAAGAAATGTCGAACAAAGAAACGCAATCCGGTGAAGAAAGAAAACGAACCAAATGATGGTAAAGACGTTGATACACCTTCGTCCGATGATTTTGTATCATCTTCAGAGCAAGCCAGTGACCACGATCATTTCATGGCTACAAAAGACACCGACTGGAAGTATTCAGAGTGTAACGTAAAGACTTCGACTGAAGATGTGACGACAGAACAGACAAACCAACCTATCGTAGAACAacagcaacaacaacaacagCAGCATTCTTGCAGCTCATGTGATTTAGTGTTTGATGGCAGCGCCTTGCTCGAGTCTCACTTGCTGTTTCACCGGCCTGAGTTGCTGGAGGAAGCCGTCTCTTCGTCGGAGTGGCGTTGCCCTCGCTGCGTAGCTCACTTTGCAAGCCAGTACGCGCTCGTGCTTCATGTTGCAGAGCATGCGGTTGCAGGAGGGAAGCCAAAGAATAAGTGTCCTCTGTGCTATAAGTCGTTTGCAACTGATGAGAGATTGGAGAGACACATGCTGGTCCACGGATCAGACGAATCCAAACCTCTGCAATGTACGACCTGTAACAAACGTTTTGTCAACAACTCTGCACTTATCTGCCACGTCAAGACACACAAGTTAGACCGGCAGATATTTGAGTGTCCTGTCTGTCGCCAGACATTTGACCAGGTCCTTCCCCACAAAGAGCACGTCAAGACACACTGTGTAAACGGCACGTACACATGTCCTCACTGCAAAAAGGACTTCAAGGAGTACAGTGTGATCCGTAAGCATATTCGCGCGTTTCACTGCGACCGTAAACACAAGTGTCTGCACTGTGATAAACCGTTCCCGACGCTTGACAAGTTACGCATGCACTTGCTCAAGCATTCGGATCACAGGGAGTTCTTGTGTGCGTCGTGTGGTAAGCAGTTCAAGCGTAAGGATAAGCTCAAAGAACACACGAAGCGTATGCACGGAGCCGGGACTGCTGCTGGAGATGCAGGAGCTGTAACGAATGCAGGTGTCTTTAGGCAAACGACAGCAGCGGATGTGAGTGCTGGTTCGAAGAGATTTGTACCAAAGGTTTCACCAACTGACTACCATCGCTTCATTTACAAATGTCACGCGTGCATGCAAGGTTTCAAACGTAGGGGTATGCTGGTGAACCACTTAGCCAAAAGACACCCGGACATCAGACCTGATACCGTGCCAGAACTCAATCTTCCTATCCTGAGAACGACCCGTGATTATTACTGCCAGTACTGTGACAAAGTCTACAAGAGCAGCTCGAAACGTAAAGCGCACATAATCAAGAACCATCCGGGAGCGACATTACCAGCGAGTAATCGTAACCGTGAGGCAGGTGCTGATACACCAGACCCTACGTTCTCACAGACGGTTGGTAGTGTGACGACTGATCCACATAACTGTCGCTGGTGTCATAAGCAGTATGCTAGTAAGGCTAAGTTACTGCAGCACCAACGGAAGAAACATCCGGAACACGTTGCTCCTAGAAGCATGAACGATATCAAACAGTGTCCTGACGATGATCCTCTCCAGCAAGAGCTAGTGGATACGTTCCCGACAGCGATGATAGAGAACGGCAACACTTACCTACGAGTGTCTGGTACCGAGCAACAAACACAAGACACGACACAGGTGTCTGTAAATGCATCTATACTTCAGTCACTGTTGACATTAGCTCCTTACCCTCCACGCTGA
Protein Sequence: MKAVLTTPLFDEEMTVWASECDEQTLSTMHSADASNNSQLLLIAVEYVNDENMGFDALNTSDGSTLPQGISQPFIYDDQVSALDPNMGSTAQYSPVYTSDSTQYNQNPIVLLPKTSDGNDNISLPVDGMYFLRQVVSSRLNQQPSLQKSNMKRESESVEFLITDQNGISYTRTQENLAASLTDQTDLSGLLSSIDQRLPEDRLLDAQGLALDSNMIGLDELVLMKSNLTNDLPQVVHHIDINIEPSITDPLPDTFKEVCNASELSEILNQEDEPLQKIDTDEYTVKMESADAPARRQPKRQFFGRDDLCDDEIIDDGTELYTVNCPDCPLDGTDELVCPRHRVQSISDKPVPSRARATLPASYLSINKVGNDENGEPIQGVFARKLIPKRTQFGPIEGVMVPLNIDKKYNIELVLESDSGEMYRLDVSDENMSNWMRFVRKATTVKNQNLLLNQIGSSLYYITTCNILPRQELRVGYSTSYADKRELKLLEREVTSVWSCFECTMTFTLYKDLQKHLCIHDKNDDKKLKSKKCRTKKRNPVKKENEPNDGKDVDTPSSDDFVSSSEQASDHDHFMATKDTDWKYSECNVKTSTEDVTTEQTNQPIVEQQQQQQQQHSCSSCDLVFDGSALLESHLLFHRPELLEEAVSSSEWRCPRCVAHFASQYALVLHVAEHAVAGGKPKNKCPLCYKSFATDERLERHMLVHGSDESKPLQCTTCNKRFVNNSALICHVKTHKLDRQIFECPVCRQTFDQVLPHKEHVKTHCVNGTYTCPHCKKDFKEYSVIRKHIRAFHCDRKHKCLHCDKPFPTLDKLRMHLLKHSDHREFLCASCGKQFKRKDKLKEHTKRMHGAGTAAGDAGAVTNAGVFRQTTAADVSAGSKRFVPKVSPTDYHRFIYKCHACMQGFKRRGMLVNHLAKRHPDIRPDTVPELNLPILRTTRDYYCQYCDKVYKSSSKRKAHIIKNHPGATLPASNRNREAGADTPDPTFSQTVGSVTTDPHNCRWCHKQYASKAKLLQHQRKKHPEHVAPRSMNDIKQCPDDDPLQQELVDTFPTAMIENGNTYLRVSGTEQQTQDTTQVSVNASILQSLLTLAPYPPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01343457;
90% Identity: iTF_01343457;
80% Identity: -