Basic Information

Insect: Sialis lutaria
Gene Symbol: Hivep2
Assembly: GCA_949319165.1
Location: OX439231.1:21031553-21039625[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.8e-05 0.00097 19.7 1.2 1 23 111 133 111 133 0.98

2 14 5.3e-06 0.00029 21.3 0.8 1 23 141 163 141 163 0.98

3 14 0.6 33 5.5 4.1 2 23 289 311 288 312 0.94

4 14 2.3 1.3e+02 3.6 0.7 1 21 361 381 361 382 0.92

5 14 0.12 6.4 7.7 0.1 1 23 549 571 549 571 0.96

6 14 1.1e-05 0.00058 20.4 0.7 1 23 581 603 581 603 0.99

7 14 0.0014 0.074 13.8 3.1 1 23 609 632 609 632 0.97

8 14 0.0014 0.073 13.8 2.1 1 23 1112 1135 1112 1135 0.95

9 14 0.0012 0.065 14.0 1.0 2 23 1440 1461 1439 1461 0.97

10 14 0.14 7.5 7.5 6.1 1 23 1467 1490 1467 1490 0.97

11 14 0.0049 0.27 12.0 1.2 1 23 1537 1561 1537 1561 0.95

12 14 0.11 6.2 7.7 1.0 1 23 1640 1663 1640 1663 0.97

13 14 0.027 1.5 9.7 0.5 3 23 1716 1736 1714 1736 0.93

14 14 0.022 1.2 10.0 5.9 1 23 1742 1764 1742 1764 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.8e-05	0.00097	19.7	1.2	1	23	111	133	111	133	0.98
2	14	5.3e-06	0.00029	21.3	0.8	1	23	141	163	141	163	0.98
3	14	0.6	33	5.5	4.1	2	23	289	311	288	312	0.94
4	14	2.3	1.3e+02	3.6	0.7	1	21	361	381	361	382	0.92
5	14	0.12	6.4	7.7	0.1	1	23	549	571	549	571	0.96
6	14	1.1e-05	0.00058	20.4	0.7	1	23	581	603	581	603	0.99
7	14	0.0014	0.074	13.8	3.1	1	23	609	632	609	632	0.97
8	14	0.0014	0.073	13.8	2.1	1	23	1112	1135	1112	1135	0.95
9	14	0.0012	0.065	14.0	1.0	2	23	1440	1461	1439	1461	0.97
10	14	0.14	7.5	7.5	6.1	1	23	1467	1490	1467	1490	0.97
11	14	0.0049	0.27	12.0	1.2	1	23	1537	1561	1537	1561	0.95
12	14	0.11	6.2	7.7	1.0	1	23	1640	1663	1640	1663	0.97
13	14	0.027	1.5	9.7	0.5	3	23	1716	1736	1714	1736	0.93
14	14	0.022	1.2	10.0	5.9	1	23	1742	1764	1742	1764	0.98

Sequence Information

Coding Sequence: ATGCAGGACGTGTTGAACGCTAACATCGCAAGGAACTGCGCCCAGACCATCTCACAACCAACCTCTCCGCCACGAGGACTGCGCTTTAACCAAGaTTCCAAAATGGAAAACACACATATAAATACcaaagaaaaatatcaaatatctaCAAGAAATCATCAACGTACCTCAACGATAAAAACgcgttttcaaataaaaatcgaCAACGAAGCAACGATGAATCATGATAACTCAATTactaaattatcaaataattcaataagTGAGGATTTAGAAAAGAATGTCTTGACTGAAAATTGTTCTCAATTAGAAGAACAAATTAAAAGTGTTTACACTTgcaaaatatgtttgaaaacATTCAACTCGAGTTCTAATTTAGATAGACATGCATCTATGCATAATTCCAACGAACAGCGCCCATTTCGATGCAAAATATGCGCTGTATCTTTTACAACTAGCGGAAATATGCAAAGACATATGAAAATCCACGGTGATAGTAAACTACCCGGAGAAAGTTATGAGTCAGATGGTAGTACAGATAGTACAAATAGCAACCATGGTGAGCATGCCCTTAGCCTTCCAAGAAAATCTTTAAGAAAACGCAGagttgaatataataataacgaTAGTCCAAGTAACGACATCAAAAGAAAATCAGAATATACTGGTACTAGTGATGATCGAGATAGTCTGTCTTCGCCTGATTCAAACCAGAACAGTAGAAGACGTTTAAAAAcgcttaataataatataaacgaTGTTTTGTCACAAAAATACCATTGTCCTGTCTGCGAGCGTGAAGATTTTGCTTccttaaatgtttttgaaactCATTTAGAAGATACACATCCTGAATACCAAATAAAATGCCAGAGTTGTAATTTAAGTTTTAAGAACCACCGTGTTTTAAACCTACATCGATACATGGTTCATCATAACACCGATACAAATCGCAAGCAAGATAGCATAGTAGGTTTCAAAGATCTTACATTCATCGATTTCTCTAGTAAAAAGTTTCCACACATTGCAAAAACTGTTTGTGAACAATCATTACACAGAGCAGAtgacaatgatatcaaatttcagtGTATGAAATGTTCTAGAGAATTCCCTTGTGATAGCGCTCTCGAAATACATcaacaaaattgtttaaatgATGACATTTATTCAAACGACGACGAAAAACATAGGCACAGAAAAAATACTGAAGAGGATTTAAAGCGAGAAAGTTTCTTCGCAGGtctcgatttaaaaaataagtctCTTGATGAAGATATGACTGAAGAAGATACAACCAAAAATGacaacgaaactaaaaatgatattcCAAAAATTCCAAAGAAAGAATATCTTTTAGTAAAGCCAGAATTAGGAACTATACCTAATTTTATTGATACAACCAAAGATTTAGCTGATATTCAATCAATAATTTCTGTTGCTTCGACTGGAAGTTTATTACAACAACTGACATCTCAGAAACCTCTGAATCTAACTCATgaacaaatacaaataaatgcacAGACAGAACTGCAGCAAATCACTCCACCTGAAAATATAATGAGACCTACTAATGAACATCAAAACGAAGAGGAGACTCAAGACCAATTTGCAGCCGAGTTCCGCAAGATGAAATTGCGCGGCGAATTCCCGTGCAGACTTTGTACAGCTGTTTTTCCGAATCTTCGAGCACTGAAAGGACACAATAGAGCTCATTTAACTGGAAGTGGATCAAACGGACCATACAGATGTAACATGTGTCCTCATAGTTCTGTTGACAAAGCAGCTTTGATCAGACACATGAGGACGCACAACGGTGATCGCCCATATGAATGCTCCTTGTGTAACTATGCATTCACTACCAAAGCTAACTGCGAAAGACACTTACGAAACAGACATGCTAAAGTAACAAGAGATGAAGTCAAACGAGCAATAATATATCACCCCTCTGAAGATCCCACCAACGATGAAATGGCTGGGAAAATGTATCATAAATCACACGACAATGCTAAAAGTTATACAGGGAGAGATGAAGTTAAAAGATCATTGATTTTCTCATCTCCACAAGAAGACCATAGAAAAGAACCTGAAATTCCAATTACACCAAATATTGctgatataaagaaaataattccaTCTATTCCTTCTCTAAACATTCCAATCACAaacaaagatattaattttaatatatctggAACTTTGGCTCCAAGTAGTATTCagaatattttgaatttaaatacatcaaaagaTCCAGCACATATGTTAAATTTAACAACtttaacaaaagaaaatttagcAGCTTTGAAAGAACAACAACCGAAAAATTCTGAAATCTTGAATTTATCTTCTTCAGCTGAAGAAAATGATTCTCAAAATATATTTCCAAAAATTAATGTGAAAAAATTCCAACCACTTAAACAAATACCAGATTATGAATCATCTACTGAAAGTCATTCAGATTCAGAAATtgatgaaaaacataaaaaccaAGTGATTTTAAACACTCCATTATCGCATTTTTATAACAGAGATACACCGCGAAATATGGATCCAATAGATCTAAGTATGGATGTATTAGATTTGAGCAAAAAGAAATCTCCTGAAATTTCAAGTCAAGATGAAACCTCAACAGCtattgcaaataaaaaagaaatagaatGTGAAGATATGGATCAACCacatgattttacaaaaaagacTTTAGAAAGTTcccaaaatttaaatacaacagCTACACCTCCAAATTCTCTTTTAGAACAGCAATTCCTATTAGCACAATTGTTTAAAGGAAGTCAAAATATCTTGAATGCTGGAATACCTCCTAATTTTTATGCAACCCAGCTGCAAAATTTATACAGATCAAATGCAAATTTAGTCAAtccacaatttttaaatatatatggcTCGCAGTTTGGGAGCTATTTTCCACCAGTGCACCCATTTTTAACACCAACTGCATCTCCTCAAGAATTACAAGAAAGAATTCACAAAGAAATTATTCGCAGTTTACAGTTAAGTGGAGGAGGTTTAATTATGGACCATGTTGGAACAGATCGATCACAAAATTTTCAAGgtATTCCTAGTATTCCAACACCTGTAAGTGAACAAAAAACAGATTCAAACTACATAACAAAATCTGAAGAAATCAAACCACTAACTATTGAAACCAACCAAGCATTCCTTGATTGTAACAAATCATTGTCACCCATAAAATCTCAATCATTAAAAACACCTGaaagtataataaatacaacACCTAATTCTGTGAAAATGGTTATCAAAAATGGTGTGTTGATGCCAAAACAAAAACAGCGTAGATACAGAACAGAGCGTCCCTTTGCATGTGAACATTGTTCAGCTCGCTTTACATTGAGATCAAATATGGAACGTCATATAAAACAACAGCATCCTCAATACTGGTCGCAGAGACAACGATCTAATATGCCTGGAGTTCCTGGAAGAAAACCTGCATCTGCCTCAATTAACTCTGAAGTTCAACAACCAAAGATGAATTTTTACAATCAACCTTTAATGCAAAATTACGATTTATCTAAATCATTCATTCCTAATCTTGATACAATACCAAATAATAGAGACAATACATTTTCTAACAATCAAACTCAACCTCTATCAATCAGTGAACATGTGAAATATGCAATTTTATCTCAACAGTTGAAACAAGTACAACAAAACAGTGTAGTTGATAGCCCTGTGTtgataaataaagaaaataatgaaGATAATTCTATAGAAGATGAAGATAATGATGCCCTTGTCATTGATGAAGAATCGCAAAGTCAAAGTCAAGAATCATCCAAAATCGACGGTTTTGATAACAACAAAAAACTCttagaagaaaaaataattaaactaaaattattacgTGAAAAACAATTACTTGAACAAGAAAAAGAAAAAGATACTACAGAAAACATAAGTGATTCTTTTAGTAATGATAATAATGTTTTGAGAAATCGTTTATTGGAATCTGATAATCctgataaaaacataaatatgacaaaaaataatgaaGAAGGTCAAGATTTGGTTTCTGTTTCAAAATTATTGGATAATGCAAGTTCTAGATTACCATTCAGAGAATATTTTAAACGTGAAGGTGATGAACATGAAACTCCTtctgaagaagaagaagagggATTGGTTGCCAGTGGTAGCACAAGTGAAGGAAATATTTCTGGAAGTGATGGAAATCGATCTGAATCTGAAACAATTCATTCGGAAAAAAGCAAAAGTAGTTCTTCGGGAGAAACTGGAAATGTTAagaaaaaatcagcatattctTTGGCACCAAATCGAGTAGTATGTCCGTATTGTCACCGAAAATTCCCTTGGACTTCTTCATTGCGACGTCATGTTTTGACTCATACAGGACAAAAACCATATAAATGTTCACATTGCCCACtattatttacaacaaaatCAAATTGTGACCGCCATTTACTACGAAAACATGGCAATCTTGTAAATAAACAATCCAATAATATATCTCAACAAAACAATTCAGTACAGCAATCAAATGCAATACAGAAAACTGATAATACTGGAGTCAATGCTCAAAATTTTGTCATGAGAAATGTTCCTGAGCGTCCATATAAATGTGCAAATTGTCCAAGTTCAACTTTCTCTACCTTGagcaacttaaaaaaacacatatcgAGTAAACATAGTATACTCGACAGTTCTAATCCTAATTCACCAAAAAGTTGTGAAGAGCAGTCACGTCCACCTAGTCAATTAGGTGGAAACTCTGGATATGAAAGCCATTCCTCTGAAGATGAACATCCGAATAAAGATGTGAAAAgtcattataataaacaaaatgacTGGGAACATCAAATAAGTCTGACTCAATCCTTAAACCAAGATCATGtcaatattcaacaaaattcaGATCTGCCATTTAAGTGTCACCTTTGTGATGGATCTTATTCTGAACGTCAAGAAGCATTAGATCATATACGAAACCAACACAAATCAGAATACGATCTTCTTATGTCAAAGAACGCTTTAGAAACACATGCAACGGATCCTGTAGATTTGTCTAACCAAAACCTTGATAACAGTGATCAGGATGAACAAAGCACTTTACGAGGAAAGTTTCCAGACTATGCCAACCGTAAAGTGATGTGTGCATTTTGCATGCGCCGGTTTTGGTCTGCAGAAGATTTGAGAAGACACATGAGAACTCACACAGGCGAACGTCCATTCTCTTGTGATGTGTGCAGACGCAGATTCACATTAAAGCATTCAATGTTGAGACATCGAAAGAAACACAGTCTTACAGAAGTTAGTCCTTCAGTTTCTGAAGATAACGGAGGTACGCACAGTGGAGATGACAACGATACTATCAAGTCACTACAAGTTTCAAACTCAATTCCAGCTGAAATAAAGGACAAAGAGGAATTAGAAAATACTGAAGGTACAGATTTGATTGGTAATTTACTAGGGATAAGAGATAAATCAATTATAGATCAAGTGCTGTTATCATCTGCTGATGATGCAGCAAAACTTTTAGgtgtaaaaaaatcagaataa
Protein Sequence: MQDVLNANIARNCAQTISQPTSPPRGLRFNQDSKMENTHINTKEKYQISTRNHQRTSTIKTRFQIKIDNEATMNHDNSITKLSNNSISEDLEKNVLTENCSQLEEQIKSVYTCKICLKTFNSSSNLDRHASMHNSNEQRPFRCKICAVSFTTSGNMQRHMKIHGDSKLPGESYESDGSTDSTNSNHGEHALSLPRKSLRKRRVEYNNNDSPSNDIKRKSEYTGTSDDRDSLSSPDSNQNSRRRLKTLNNNINDVLSQKYHCPVCEREDFASLNVFETHLEDTHPEYQIKCQSCNLSFKNHRVLNLHRYMVHHNTDTNRKQDSIVGFKDLTFIDFSSKKFPHIAKTVCEQSLHRADDNDIKFQCMKCSREFPCDSALEIHQQNCLNDDIYSNDDEKHRHRKNTEEDLKRESFFAGLDLKNKSLDEDMTEEDTTKNDNETKNDIPKIPKKEYLLVKPELGTIPNFIDTTKDLADIQSIISVASTGSLLQQLTSQKPLNLTHEQIQINAQTELQQITPPENIMRPTNEHQNEEETQDQFAAEFRKMKLRGEFPCRLCTAVFPNLRALKGHNRAHLTGSGSNGPYRCNMCPHSSVDKAALIRHMRTHNGDRPYECSLCNYAFTTKANCERHLRNRHAKVTRDEVKRAIIYHPSEDPTNDEMAGKMYHKSHDNAKSYTGRDEVKRSLIFSSPQEDHRKEPEIPITPNIADIKKIIPSIPSLNIPITNKDINFNISGTLAPSSIQNILNLNTSKDPAHMLNLTTLTKENLAALKEQQPKNSEILNLSSSAEENDSQNIFPKINVKKFQPLKQIPDYESSTESHSDSEIDEKHKNQVILNTPLSHFYNRDTPRNMDPIDLSMDVLDLSKKKSPEISSQDETSTAIANKKEIECEDMDQPHDFTKKTLESSQNLNTTATPPNSLLEQQFLLAQLFKGSQNILNAGIPPNFYATQLQNLYRSNANLVNPQFLNIYGSQFGSYFPPVHPFLTPTASPQELQERIHKEIIRSLQLSGGGLIMDHVGTDRSQNFQGIPSIPTPVSEQKTDSNYITKSEEIKPLTIETNQAFLDCNKSLSPIKSQSLKTPESIINTTPNSVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQYWSQRQRSNMPGVPGRKPASASINSEVQQPKMNFYNQPLMQNYDLSKSFIPNLDTIPNNRDNTFSNNQTQPLSISEHVKYAILSQQLKQVQQNSVVDSPVLINKENNEDNSIEDEDNDALVIDEESQSQSQESSKIDGFDNNKKLLEEKIIKLKLLREKQLLEQEKEKDTTENISDSFSNDNNVLRNRLLESDNPDKNINMTKNNEEGQDLVSVSKLLDNASSRLPFREYFKREGDEHETPSEEEEEGLVASGSTSEGNISGSDGNRSESETIHSEKSKSSSSGETGNVKKKSAYSLAPNRVVCPYCHRKFPWTSSLRRHVLTHTGQKPYKCSHCPLLFTTKSNCDRHLLRKHGNLVNKQSNNISQQNNSVQQSNAIQKTDNTGVNAQNFVMRNVPERPYKCANCPSSTFSTLSNLKKHISSKHSILDSSNPNSPKSCEEQSRPPSQLGGNSGYESHSSEDEHPNKDVKSHYNKQNDWEHQISLTQSLNQDHVNIQQNSDLPFKCHLCDGSYSERQEALDHIRNQHKSEYDLLMSKNALETHATDPVDLSNQNLDNSDQDEQSTLRGKFPDYANRKVMCAFCMRRFWSAEDLRRHMRTHTGERPFSCDVCRRRFTLKHSMLRHRKKHSLTEVSPSVSEDNGGTHSGDDNDTIKSLQVSNSIPAEIKDKEELENTEGTDLIGNLLGIRDKSIIDQVLLSSADDAAKLLGVKKSE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01343421;
90% Identity: iTF_01343421;
80% Identity: -