Basic Information

Insect: Sialis lutaria
Gene Symbol: -
Assembly: GCA_949319165.1
Location: OX439232.1:1416616-1424302[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.16 8.7 7.3 1.3 6 21 12 27 7 28 0.88

2 14 7.2 3.9e+02 2.1 0.1 1 12 164 175 164 182 0.90

3 14 0.15 8.3 7.3 4.0 1 20 329 348 329 350 0.94

4 14 3.9e-05 0.0021 18.6 0.6 1 23 357 379 357 379 0.98

5 14 2.7e-05 0.0015 19.1 1.4 1 23 393 415 393 415 0.95

6 14 0.2 11 7.0 0.2 1 23 447 468 447 468 0.89

7 14 6.2e-06 0.00034 21.1 6.4 1 23 474 496 474 496 0.98

8 14 0.00088 0.048 14.4 0.8 1 23 502 524 502 524 0.97

9 14 6.2e-05 0.0033 18.0 1.6 1 23 530 552 530 552 0.98

10 14 1.1e-06 5.8e-05 23.6 4.2 1 23 558 580 558 580 0.98

11 14 0.001 0.055 14.2 4.9 1 23 586 608 586 608 0.98

12 14 0.00016 0.0085 16.7 0.2 1 23 614 636 614 636 0.98

13 14 6.8e-05 0.0037 17.9 0.1 1 23 640 662 640 662 0.98

14 14 0.00059 0.032 14.9 0.6 1 23 670 693 670 694 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.16	8.7	7.3	1.3	6	21	12	27	7	28	0.88
2	14	7.2	3.9e+02	2.1	0.1	1	12	164	175	164	182	0.90
3	14	0.15	8.3	7.3	4.0	1	20	329	348	329	350	0.94
4	14	3.9e-05	0.0021	18.6	0.6	1	23	357	379	357	379	0.98
5	14	2.7e-05	0.0015	19.1	1.4	1	23	393	415	393	415	0.95
6	14	0.2	11	7.0	0.2	1	23	447	468	447	468	0.89
7	14	6.2e-06	0.00034	21.1	6.4	1	23	474	496	474	496	0.98
8	14	0.00088	0.048	14.4	0.8	1	23	502	524	502	524	0.97
9	14	6.2e-05	0.0033	18.0	1.6	1	23	530	552	530	552	0.98
10	14	1.1e-06	5.8e-05	23.6	4.2	1	23	558	580	558	580	0.98
11	14	0.001	0.055	14.2	4.9	1	23	586	608	586	608	0.98
12	14	0.00016	0.0085	16.7	0.2	1	23	614	636	614	636	0.98
13	14	6.8e-05	0.0037	17.9	0.1	1	23	640	662	640	662	0.98
14	14	0.00059	0.032	14.9	0.6	1	23	670	693	670	694	0.95

Sequence Information

Coding Sequence: ATGGGTTCAATTCAATTGGACTGTCCACTATGTTGTGGtgaaaaattttcaaaccatcAATCtctaaaatatcatttattgaGTATGACAGTTAATTTATACTGTCCAGCTTGCAATCAACTATGCGACAATTTTCAACAAATAATAGACCATTTAGACAGTGAGTGTTCAAGCAAAGAAGAACAATTTGAAAAAGTAGTATTTAAACAAGAACCATCTGATGAAACAACTGATAGTACATTAAACGAAAGATATTTAGAAGAAGAAAATAGAAACAATGAAGAAGAAAGTGATGAAGTGGTTCTTGATAAACTTAACGAAAGTGAGTTACAAGAAAATAGTGATTCGAGTGAGATTAAAGACCAAATGCAAACTgtgattttaaaaagtaatgaaAACCAAGGCATTAATGGTTCCGTTGTGATATCTGGAGAAGACGGCGAGCAGATGGAAGTTATAGAAATATCTGAGAACGTCGACCAGGAGTTCTATTCGTGTTCTAGCTGCGGAGTGAACTTTGTTTCAGTGATGGACCATATTCAAGAGTACCACGACGGGCAGGAAGTGGTCGTAGagATGACAGAAAACGACACAGAACTTCCCGAAAACACAGACGACACAACGTTAGTCGTATACCCCGTCGAACAATCGGAAATCCTCACAGCAGAACACCTCGAGGAAGAATACGAAACCGAGGAAGAACCCGAAGAAGTCCAAGTAAAATACAACCCTCAGATCTTAAACACTTTAAAACAAGAAGACTGCATCGACAAAGACGGCCGTTTATACACCCGCAAAGTCGTCCAAATCGAGAAATTCTGGGACGACAACCTAGCCCAGAAAGCCCTACGCGGTGCCAACAGACGTCAAGCGATCGTAGAACACTACGCAGTCGATGAATCCGGAATGCTAACTAAAGCTACCAAAGACCAGATCGAGGAAGATAAAAATGTGGATGAACAAAACACGAAACTCGTGAAACTGTTCAACTGCAGCCGTTGCAAGATGCAGTTCTCTAAGATCAGTCAGTTCAACCGGCATACGTGCGACCCAGAAAAAACAAGCGAATACGCGTGTTCTTTATGCGTCGCGACGTTCAGTAACCCTAAATCTCTATGTGCTCACATGAAGGTTCATAAGATCAACAGGCCGGACGAGCCTCAGGCCGTGGCCCCGTTTTTGTGTTATAAGTGCGATACAGTGTTCCCGACGAATAAGTCCCTGAGGCTCCATCAAAGGATGCACGAGCCGATTAAAGCTAAAGAGATCGAAGCGCCTGTAGAATATGGAATCACCGGAGAGACGCTTGAAGTTGATCCGAATAAACCTAGAGAGATGTTTGTTTGTGGTGTGTGTAATAAGACTTACGATAAGGGGTACGAGAGCGTGCACATGGCGACGCATAACGGAGTGAACGATTACCACTGTCATATTTGTAATAGGAAGTTTTTCACGCAGGAGAATTTGAAGATGCATATGAGGGTGCATAATGGAGGGAAGTTGTTCAGTTGTACGTACTGTAAGGCGACGTTTGAGTCTAATGAGAAGCTAAGTGAGCATACGGAGATTCATAGTAAGGATAGGCCGTATCGGTGTGGATATTGTGGTAGAAAATTCGCCCGTCCACACGAGAAAGTCAAACACGAGCGAATCCACACGGGCGAAAGACCCCACGAGTGCGAAATCTGCGGCAAGACGTTTAGAGTGAGCTACTGCCTGACCCTGCACATGCGCACGCACACGGGCGCCCGTCCTTACGTGTGCAAGCAGTGCGGCAAGCGGTTCAAAGCGCACAGCGTCTACAACCACCACCTTCTAACGCACTCCGACTCTCGTAACTACAAGTGCCCGTTCTGCCCTAAGGCGTTCAAGACCGGCGTCCAGCTGGCCGGGCACAAGAACAGCCACACTAAACCGTTCAGCTGCACGGAGTGCAACAGGCCGTTCGCGTCGCTGTACGCCGTAAGGGCGCACATGGAGAGCCATAAGCGCGAGAATAACTTAAAGTTTAGTTGTTATCTGTGCGGTGCGTCGTACGCGAGGAACTTTGCCCTTAAAGATCATATCAAGGAGGTGCATCATAATGATGTGATGATTGTTGATACGGAGGCTACAGATGAGTTAAATGATAAGATTGGGCTCGTTGATTTGGAAGGGTTGAAGGCTACGACGAGTATTTTACAGGATGATGAGACGGAGATGGCGTTGAATCAGTTAAGGGATGATATTGAAGAGGAAGTTATATAA
Protein Sequence: MGSIQLDCPLCCGEKFSNHQSLKYHLLSMTVNLYCPACNQLCDNFQQIIDHLDSECSSKEEQFEKVVFKQEPSDETTDSTLNERYLEEENRNNEEESDEVVLDKLNESELQENSDSSEIKDQMQTVILKSNENQGINGSVVISGEDGEQMEVIEISENVDQEFYSCSSCGVNFVSVMDHIQEYHDGQEVVVEMTENDTELPENTDDTTLVVYPVEQSEILTAEHLEEEYETEEEPEEVQVKYNPQILNTLKQEDCIDKDGRLYTRKVVQIEKFWDDNLAQKALRGANRRQAIVEHYAVDESGMLTKATKDQIEEDKNVDEQNTKLVKLFNCSRCKMQFSKISQFNRHTCDPEKTSEYACSLCVATFSNPKSLCAHMKVHKINRPDEPQAVAPFLCYKCDTVFPTNKSLRLHQRMHEPIKAKEIEAPVEYGITGETLEVDPNKPREMFVCGVCNKTYDKGYESVHMATHNGVNDYHCHICNRKFFTQENLKMHMRVHNGGKLFSCTYCKATFESNEKLSEHTEIHSKDRPYRCGYCGRKFARPHEKVKHERIHTGERPHECEICGKTFRVSYCLTLHMRTHTGARPYVCKQCGKRFKAHSVYNHHLLTHSDSRNYKCPFCPKAFKTGVQLAGHKNSHTKPFSCTECNRPFASLYAVRAHMESHKRENNLKFSCYLCGASYARNFALKDHIKEVHHNDVMIVDTEATDELNDKIGLVDLEGLKATTSILQDDETEMALNQLRDDIEEEVI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01343348;
90% Identity: iTF_01343348;
80% Identity: -