Basic Information

Insect: Sialis lutaria
Gene Symbol: -
Assembly: GCA_949319165.1
Location: OX439242.1:7678119-7685852[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00019 0.01 16.5 1.8 1 23 154 176 154 176 0.94

2 15 0.002 0.11 13.3 1.1 3 23 184 204 183 204 0.99

3 15 0.00016 0.0089 16.7 0.1 1 23 312 334 312 334 0.98

4 15 0.76 41 5.1 0.2 1 23 340 363 340 363 0.95

5 15 5.6e-05 0.003 18.1 3.5 1 23 389 411 389 411 0.98

6 15 0.14 7.6 7.4 0.0 1 23 424 446 424 446 0.95

7 15 0.026 1.4 9.7 0.3 1 23 452 475 452 475 0.93

8 15 0.08 4.3 8.2 1.4 3 19 484 500 483 501 0.95

9 15 1e-05 0.00057 20.4 5.5 1 23 510 532 510 532 0.98

10 15 0.0092 0.5 11.2 0.4 2 23 538 559 537 559 0.96

11 15 1.4e-05 0.00074 20.1 0.4 1 23 567 589 567 589 0.98

12 15 0.0059 0.32 11.8 0.2 3 23 597 617 595 617 0.97

13 15 0.00019 0.01 16.5 0.3 1 23 623 645 623 646 0.95

14 15 0.014 0.74 10.6 1.1 1 23 660 682 660 682 0.96

15 15 0.00064 0.035 14.8 0.2 1 20 1074 1093 1074 1096 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00019	0.01	16.5	1.8	1	23	154	176	154	176	0.94
2	15	0.002	0.11	13.3	1.1	3	23	184	204	183	204	0.99
3	15	0.00016	0.0089	16.7	0.1	1	23	312	334	312	334	0.98
4	15	0.76	41	5.1	0.2	1	23	340	363	340	363	0.95
5	15	5.6e-05	0.003	18.1	3.5	1	23	389	411	389	411	0.98
6	15	0.14	7.6	7.4	0.0	1	23	424	446	424	446	0.95
7	15	0.026	1.4	9.7	0.3	1	23	452	475	452	475	0.93
8	15	0.08	4.3	8.2	1.4	3	19	484	500	483	501	0.95
9	15	1e-05	0.00057	20.4	5.5	1	23	510	532	510	532	0.98
10	15	0.0092	0.5	11.2	0.4	2	23	538	559	537	559	0.96
11	15	1.4e-05	0.00074	20.1	0.4	1	23	567	589	567	589	0.98
12	15	0.0059	0.32	11.8	0.2	3	23	597	617	595	617	0.97
13	15	0.00019	0.01	16.5	0.3	1	23	623	645	623	646	0.95
14	15	0.014	0.74	10.6	1.1	1	23	660	682	660	682	0.96
15	15	0.00064	0.035	14.8	0.2	1	20	1074	1093	1074	1096	0.93

Sequence Information

Coding Sequence: atggaTGAATCTTTTAATCTTACCTGGGACGATGGGCCCAACGTGGCTCATCGAGAAGAAGTAATATGTGGAATAGATGAAAATAATTTACCTTCCAATAATACGGAGTACGTGGAGATGTGCGAAGATGTCGTAGTGCAAGAAATAGCAAACGAAACTGTTATAACAGATGATCAGCAGGGCGAGGAAGTTGTATTCATGCAAGAAAATTATCAATCAGATAATGTTGTTTATATGCCGCAAGATAATGTACTTGTCGTACAACAAAATGAGGAAGTTCCGTTATCGGATCAACAATATATGGAATGTCAAGTTGCAGAAGAAGTTATTACTGATGAATGGGTGCAAGGAGAAGGAAGAGTTGAAGTTATTGGCGACATATCTGCACAAGGTTCAGGAGGGGACGACATTGACATTCCATTATCTGTTGATCAAGATGAATATACAGCTAGTAGACCACATCCTTGTGACTTTTGCAGTAGACGGTTCAGAAAGAAAGCAAATCTAATGAATCACATGGTAGCTCATCAAACGGACAGACCTCATGGCTGTAATTTGTGTGGAGCTCGATACATAAGAAAGTGTGATTTAATGAATCATTTGAAAATACATGCTTATGCACCAGAGCCAGAAGGATATGAAGAGAATGAAGATGATTATCAGGTGGAATCAGATTATGAGAAGCCTCATAAGAAGAAATCAAACTCTAAGAAACGAAAATCAATGAAGactaaaataaaacaagaaacTGAAGAAGAGAAATACTCTAGGTCTTATGACTACGTTGATGAGGACATGCGACTGTTGACGGAGATGGCAAATAATTCATCAAGAACATTCGAATATGATACTGCAAATTATTCTGAAGCAATTCCTCCAGAGAATCATCCAATAAGCGAACCGagGTATCCTATCACGGATCCACGAAAACCTTTTGTGTGTCAACACTGTGGTGTTGGTTTTGCAAGAGAAAAGGCTTTAGCTTCTCATGCCCGGATTCATCTTGGCGATAGTCCTTTTGAATGTGAAACTTGCGGAGACATGTTTTGGGACATTACTTTATTGAAAGAACACGTGAGAAATAAACACGGAGACACAGGTGCTGTTTCCTATGATGACGATGATGATGAAGACTACGTAGAAGATGAAGAGAAATATGGTGAATTTTACTGTCAGACATGTGGTATGTCGTTTCACAGACAGGACTTGTTACGGAGACATTCTCGTATTCATGTCAAGGAAGAATATGTTAATGAAGCTGAGTTCGGACATGTCTGTAATGTTTGTGGCGATTCATTTCCAGAAGCACTGGATTTATTAGCTCACGCTGAAGTACATGCAAGGTTAGATGTACATCGATGTATGTTATGTGGAGAAAGTTTCTCAGAAGAGCAGGCGATGGCAACGCATATCGCGCAGCGGCACGCAAAGAACATGCCACCGAACTCGTGCATGCTGTGCGGCAAGGCTTGCAAGGACAGGCGCACACTGCTCAAGCACTCGTGGGAGCACTCACGCGAGAAGGCGTTCTCCTGCTCCAAGTGCGGCAAGTGTTTCTATAACAAGGCGAGATTGAAGCGCCACATGTCCTCGCATCGTAATAAGGTCGTGTCGTGTGAGGTTTGTGGACAAGATTTCCCTGATGGAAGGTCTCTGATGAATCACAGACATAGCCACTCTAACATGGCTGGGAGACAGTTTCCTTGCCGTGAGTGCGGCAAGACGTTCGGGTCCCGGAGTTCGCAACAAATCCATATAAGAATACACACCGGGGAGAGACCGTACGGATGCCGGTTTTGTTGGAAGGCGTTTGCAGACGGTGGTACTCTCAGAAAACATGAACGGATACATACAGgagAAAAGCCATACGCATGTGCCGTATGCCCTCGAGCATTCAACCAGCGAGTTGTTCTCCGTGAACACATTCGTTCTCATCATTCAGGTCCGGACCCTAAATACGGTACGAGCCTCACGCCATATTGCTGTAACGTGTGCAGTAATCTGTTCAGTACCTCACAAGATTTGATTGTACATCTCATTCAACACTGTGACTTCAATACAGCCATGAAACGTCAACCTCAAATGGGGCCTCGTAAGTATAAACGTCGTAGAAAACTCAAACCTCATGAGTTGGAACGATTGTCCAATAGAATGGACAGAGAAGAAACAGAAACGGCTGTAGCCAATTTGTCTGATTCAGATAACGAAGTTCGGAGGAAGATTGTCAAAAGAAATCGAAAACCAAAAGTACCCCTCGAAGAGGATTACGAATCAATGTGTCAAAGCGTTGAATCAGCTGTCCAGACAATCAATAGCATTGTTAACTCCAAACCCAGTAATAGAGGCCGGAAAAAGAAAATCGTTGCTGCTGTGAATGATAATCAAGCACCAGTGCCATCAAGACCAAAAATGATTTATACACAGAAAACAAGAGTGGCTGTTGAAGTAAATACACCAGAAGGTAGTAAGATCAGACACAAAACTAAAACATTGGTCACTCGATCTACTCCGTCGGCAGCATCATCAAACAGCAATGTATCAGAAGTTCCTAAAAATGGAGAAAGAAATAGACCAAGAACAAAGAACGTCAGCTATCATGTTTATCAACCAGAGAAATACCCAGTGGCCACGTTCAATTCAACTGACGATAGAATAAAATCAGAACCAAAGTCGTCTAATGACGTAACAGTTAAAACAGAATTGAGAGATTCTGTTGATGAGGTAACTTCTGAAATGTTCAACAATGTACCAATTGAAGATAATCCAACTAACTCTGCACTTGGATTAGAAAACGACTTACACGATCATGTAGCACAAAATATTGAAATCTCTGCTTCTGATAGTGTACCAGAAGCTGCTAATGAAGTATGTATCGGTGAAGAAGTGATGAGTGAAGTAAATGGAAACAGTGAAATCAAGAATAATACAAGAGTTTATAAACCAGTAACTAACACGAGGAAGTCTCCAGGTCGTCCGAGAGCTAAATCGGTACGACCGGTTGCAGTAAATATCATTAAAGTAGTAAAAAAATCTACCCGAAAGATAAATAAAGAACAAGGCAAAAATCAGTTTATGGAAATATTAAACAATTCAATGGAATCAAATGAAATGGTTTTGCCAGATATGCAAGAACCTGTTGTAAATGTGAAATTAGAGCCGATGGAAACGACATCACTACACGAGTTAGCAGAGTTGTCGATGCAACACGCTCAGAGTCAATTTAAGTGTGAAATGTGTAGCGAGAGTTTTTCAGATCGAGAACAACTACTACTTCACGTTCCAATACATATATGA
Protein Sequence: MDESFNLTWDDGPNVAHREEVICGIDENNLPSNNTEYVEMCEDVVVQEIANETVITDDQQGEEVVFMQENYQSDNVVYMPQDNVLVVQQNEEVPLSDQQYMECQVAEEVITDEWVQGEGRVEVIGDISAQGSGGDDIDIPLSVDQDEYTASRPHPCDFCSRRFRKKANLMNHMVAHQTDRPHGCNLCGARYIRKCDLMNHLKIHAYAPEPEGYEENEDDYQVESDYEKPHKKKSNSKKRKSMKTKIKQETEEEKYSRSYDYVDEDMRLLTEMANNSSRTFEYDTANYSEAIPPENHPISEPRYPITDPRKPFVCQHCGVGFAREKALASHARIHLGDSPFECETCGDMFWDITLLKEHVRNKHGDTGAVSYDDDDDEDYVEDEEKYGEFYCQTCGMSFHRQDLLRRHSRIHVKEEYVNEAEFGHVCNVCGDSFPEALDLLAHAEVHARLDVHRCMLCGESFSEEQAMATHIAQRHAKNMPPNSCMLCGKACKDRRTLLKHSWEHSREKAFSCSKCGKCFYNKARLKRHMSSHRNKVVSCEVCGQDFPDGRSLMNHRHSHSNMAGRQFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACAVCPRAFNQRVVLREHIRSHHSGPDPKYGTSLTPYCCNVCSNLFSTSQDLIVHLIQHCDFNTAMKRQPQMGPRKYKRRRKLKPHELERLSNRMDREETETAVANLSDSDNEVRRKIVKRNRKPKVPLEEDYESMCQSVESAVQTINSIVNSKPSNRGRKKKIVAAVNDNQAPVPSRPKMIYTQKTRVAVEVNTPEGSKIRHKTKTLVTRSTPSAASSNSNVSEVPKNGERNRPRTKNVSYHVYQPEKYPVATFNSTDDRIKSEPKSSNDVTVKTELRDSVDEVTSEMFNNVPIEDNPTNSALGLENDLHDHVAQNIEISASDSVPEAANEVCIGEEVMSEVNGNSEIKNNTRVYKPVTNTRKSPGRPRAKSVRPVAVNIIKVVKKSTRKINKEQGKNQFMEILNNSMESNEMVLPDMQEPVVNVKLEPMETTSLHELAELSMQHAQSQFKCEMCSESFSDREQLLLHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01343329;
90% Identity: iTF_01343329;
80% Identity: -