Basic Information

Insect: Sialis lutaria
Gene Symbol: -
Assembly: GCA_949319165.1
Location: OX439233.1:25232145-25234433[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0079 0.43 11.4 0.7 2 23 127 148 126 148 0.94

2 14 4.9e-06 0.00026 21.5 3.2 2 23 155 176 154 176 0.97

3 14 8.3e-06 0.00045 20.7 2.2 1 23 182 204 182 204 0.98

4 14 0.027 1.5 9.7 1.4 1 21 210 230 210 231 0.92

5 14 3.3e-06 0.00018 22.0 0.0 1 23 238 260 238 260 0.96

6 14 2.3e-05 0.0012 19.4 4.8 3 23 376 396 374 396 0.96

7 14 7.3e-06 0.00039 20.9 2.5 1 23 402 424 402 424 0.98

8 14 0.00038 0.02 15.5 0.4 1 23 430 453 430 453 0.95

9 14 0.00071 0.039 14.7 0.6 1 23 465 487 465 487 0.88

10 14 0.019 1 10.2 0.8 1 21 495 515 495 516 0.93

11 14 6e-06 0.00032 21.2 2.4 1 23 524 546 519 546 0.96

12 14 6.5e-06 0.00035 21.1 1.7 1 23 552 574 552 574 0.98

13 14 1.5e-05 0.0008 20.0 0.8 5 23 584 602 580 602 0.93

14 14 2.1e-05 0.0011 19.5 2.0 1 23 608 630 608 630 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0079	0.43	11.4	0.7	2	23	127	148	126	148	0.94
2	14	4.9e-06	0.00026	21.5	3.2	2	23	155	176	154	176	0.97
3	14	8.3e-06	0.00045	20.7	2.2	1	23	182	204	182	204	0.98
4	14	0.027	1.5	9.7	1.4	1	21	210	230	210	231	0.92
5	14	3.3e-06	0.00018	22.0	0.0	1	23	238	260	238	260	0.96
6	14	2.3e-05	0.0012	19.4	4.8	3	23	376	396	374	396	0.96
7	14	7.3e-06	0.00039	20.9	2.5	1	23	402	424	402	424	0.98
8	14	0.00038	0.02	15.5	0.4	1	23	430	453	430	453	0.95
9	14	0.00071	0.039	14.7	0.6	1	23	465	487	465	487	0.88
10	14	0.019	1	10.2	0.8	1	21	495	515	495	516	0.93
11	14	6e-06	0.00032	21.2	2.4	1	23	524	546	519	546	0.96
12	14	6.5e-06	0.00035	21.1	1.7	1	23	552	574	552	574	0.98
13	14	1.5e-05	0.0008	20.0	0.8	5	23	584	602	580	602	0.93
14	14	2.1e-05	0.0011	19.5	2.0	1	23	608	630	608	630	0.98

Sequence Information

Coding Sequence: ATGGAAAATACAAATTATGATTTTGACCGCATATGTCGTGCTTGTAAAGCAGAAACTTCAGATTTGCAgtcgatttttgaaataaataactctGTGAAGAATGAATCATCAAAACTTTCAGAAATGATGATGGAGTGTACTTCTGTACAAATATTGGTTGGTGATGGTTTACCAAATTCAATGTGTGTCCAATgtgttgttaaattaaaaaacgcaTATGACTTTAAAAAACAATGTGAAGTTACAGACACTTCTCTACGTTTTTACATGcaacaaaagaaaataaaaatagaagaaCAAGATGACGATAGTTTTGATGATCAAAGTATTTCACAGGTCCTCCATGAAAAAATCGAACCTCCGCATGAAAGTGTATTATCATGCGCTGCGTGTCCAAAGAAATTCACAACATTATTGGGAttaaaaacacacaaaaaaagTCATGAAAAAGAAAACAGTTTGAAATGTAAAATTTGTCTCAAAGAATTTACATATTACAGTCATTTACAAAGACACATGAATATTCATAATCcgcaaaaaatttacatttgtaaaatttgtgaaaaacggtTAACTCGTTTGGAACATCTCAAACGGCATATGGTTACTCATCTGAAAACCAAACCTCATGCTTGCAGAATATGTAAACGTGGTTTTAACCACatagaaaatttgtataatcaTGAAAAGCGTTGCAAAGGAGATAAGAAATACGTGTGTGAGATTTGTAATCGAGGCTTCACTAGAGCAGATGCTCTAGAAGCGCACATGGGTAATCACGAGCAAGCCGGTAATGTAAAACCAATGCTCGATTCTCTTGACAACATTGATAACTACATTAAAGTTGAAAGTTTTGATGGTGAAACTGTTGACATTCAAGATTTCATTGAACCTCAAGTTATTATAGAAGACTTTAAATCTAGTGATCTTATCAGTAAATGTGAGAAAACAAACCTAGAAATTCCAGAAGAAGAATTATTAAAACTGAATGTAGCATGTTCTGAAGATGATCTAAAATTAACAGAGCTTGCTGATATTCCTATAGTGAGAAAACGTGGACGTCCTCGGAAGAATGAAGTTAGACCTCCAAGAAATCTGCGAAATAGTGCTTTTAAAGCTACCAACTGCAGAGTTTgtcaaagaaaatttaaaagattGAGCCATTTACAACGTCACATGCTTTCTCATGGAGAAAGTAAAGCTTTTCAGTGCGAACTATGTTGGAAAACTTTTGGTCGTAAAGATCATATGGTACGACATATGAAACTACACAGTGTCAAGAAAGAATTCAAATGTGAATTGTGTAGTAGAGAATTTGTACGTGAAGAACAATTGATCCAACATAAAGCTGTCAAACATGATATCGGACAAAGAATTGTTGtagagaaaaaatacaaatgtcCTATTTGTACGAAGAGTTTTACAACTGAAAAATACAGAGATATACATGTTGAAGCTCATGGAAAAGAAAAACGTAAAATTTACGATTGTAAGAACTGTCacttaatatttaattcaaaagAAGAATTTGCTGAACATGAAAAACAAAGCCCAGAGTGTTCAAAGAAATTCTTATGTTCTGAATGTGGCCAACGATTTATTAGAAAGAATTATTTGATTGTTCATATGAGAAGACATCGAGGAGAAAAACCATTCAAATGTAAATACTGCGGCAAAggATTCCCTCGATCGACTGATGTAACAAGACATGAAAAGTATCATACGGGTGAAAAGAATCATTTGTGTATAATATGTGGAAAAGGATTTGGGCGAGCCTATAATCTTACACTGCACATGAGAACTCATACAGGTGAAAAACCATATCATTGCAGTTATTGCGATGCAGCGTTTGCACAAAGCAACGACCTTAAATCTCACACTCGCAGACACACAGGAGAGAGATATCATTGTGATTTGTGTACAGATACTTTCCTTATGGGCTACCTCTTAAAACAGCATAAGCGTAATGTCCACGGTCTTGATTTACCTTCACAACGTGTGCAACCTGCACACGTTTTACAGAGTATGCAAAATATGCAGCAAGCTGTTCAGAATGCTATGCCTATTCCTCGCCCTTcttga
Protein Sequence: MENTNYDFDRICRACKAETSDLQSIFEINNSVKNESSKLSEMMMECTSVQILVGDGLPNSMCVQCVVKLKNAYDFKKQCEVTDTSLRFYMQQKKIKIEEQDDDSFDDQSISQVLHEKIEPPHESVLSCAACPKKFTTLLGLKTHKKSHEKENSLKCKICLKEFTYYSHLQRHMNIHNPQKIYICKICEKRLTRLEHLKRHMVTHLKTKPHACRICKRGFNHIENLYNHEKRCKGDKKYVCEICNRGFTRADALEAHMGNHEQAGNVKPMLDSLDNIDNYIKVESFDGETVDIQDFIEPQVIIEDFKSSDLISKCEKTNLEIPEEELLKLNVACSEDDLKLTELADIPIVRKRGRPRKNEVRPPRNLRNSAFKATNCRVCQRKFKRLSHLQRHMLSHGESKAFQCELCWKTFGRKDHMVRHMKLHSVKKEFKCELCSREFVREEQLIQHKAVKHDIGQRIVVEKKYKCPICTKSFTTEKYRDIHVEAHGKEKRKIYDCKNCHLIFNSKEEFAEHEKQSPECSKKFLCSECGQRFIRKNYLIVHMRRHRGEKPFKCKYCGKGFPRSTDVTRHEKYHTGEKNHLCIICGKGFGRAYNLTLHMRTHTGEKPYHCSYCDAAFAQSNDLKSHTRRHTGERYHCDLCTDTFLMGYLLKQHKRNVHGLDLPSQRVQPAHVLQSMQNMQQAVQNAMPIPRPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01343293;
90% Identity: iTF_01343293;
80% Identity: -