Basic Information

Insect: Sialis lutaria
Gene Symbol: ZNF219
Assembly: GCA_949319165.1
Location: OX439240.1:815099-817447[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 4.9e-06 0.00027 21.5 3.1 1 23 123 144 123 144 0.98

2 11 4.2e-05 0.0023 18.5 3.3 1 23 150 172 150 172 0.97

3 11 6.2e-05 0.0034 18.0 5.7 1 23 186 208 186 208 0.97

4 11 1.8e-06 0.0001 22.8 0.1 1 23 214 236 214 236 0.97

5 11 2.9e-05 0.0016 19.0 1.2 1 23 242 264 242 264 0.97

6 11 1.6e-05 0.00087 19.8 0.5 1 23 285 307 285 307 0.97

7 11 4.6e-05 0.0025 18.4 0.3 1 23 312 334 312 334 0.95

8 11 0.0002 0.011 16.4 3.7 1 23 340 362 340 362 0.97

9 11 8.7e-07 4.7e-05 23.8 8.8 1 23 368 390 368 390 0.98

10 11 2.4e-07 1.3e-05 25.6 2.2 1 23 396 418 396 418 0.97

11 11 8.9e-07 4.8e-05 23.8 0.5 1 23 424 446 424 446 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	4.9e-06	0.00027	21.5	3.1	1	23	123	144	123	144	0.98
2	11	4.2e-05	0.0023	18.5	3.3	1	23	150	172	150	172	0.97
3	11	6.2e-05	0.0034	18.0	5.7	1	23	186	208	186	208	0.97
4	11	1.8e-06	0.0001	22.8	0.1	1	23	214	236	214	236	0.97
5	11	2.9e-05	0.0016	19.0	1.2	1	23	242	264	242	264	0.97
6	11	1.6e-05	0.00087	19.8	0.5	1	23	285	307	285	307	0.97
7	11	4.6e-05	0.0025	18.4	0.3	1	23	312	334	312	334	0.95
8	11	0.0002	0.011	16.4	3.7	1	23	340	362	340	362	0.97
9	11	8.7e-07	4.7e-05	23.8	8.8	1	23	368	390	368	390	0.98
10	11	2.4e-07	1.3e-05	25.6	2.2	1	23	396	418	396	418	0.97
11	11	8.9e-07	4.8e-05	23.8	0.5	1	23	424	446	424	446	0.97

Sequence Information

Coding Sequence: atggaaataaataattatgaaaagaTTTGCAGAACCTGTTTACGAGAAGTACCTTTACAATCTGTTTTTACTGAAAATCCTATCGAAGATGATGGAAATAACGTGAAACATATATCTGACATGTTAATAGAGTGTACTTCTGTCAAAATATGCAAAGACGACATCCTCCCTTTAAACATATGTTCTGAATGCATAAATCAACTGATACAAGTATATAAATTCCGAAAAAAATGCGAAAACAACGAAAAAATTTTAGAAGAATCTCGACAGTATTATAACGACAGTTCTAACAGTGATATTAACGACGAAACCGACGTATGCGACACAAAACACGTCAAACCTAAACGGCATCCAATGAAGAGGGACCACAAATGCGACATATGCCAGAAATCATTCACCACATCGCAGCTCAAGATACATATGCGTATCCATACTAAAGAACGCCCTTTCACGTGCTCGTACTGCGGCCAACAGTTCAGCCTGAACTGCAACCTGAGAAGGCACGTCATGCTTCACAccgggGAACAACCGAAAAGGCACGGTATCGATAAGCAACACACGTGCGAAGTATGTGGACAGCGTTTCAGCTTCAAGTGCAATCTGAAACGTCACGCGATGAGGCACACTCAAGAAAGACCCCACGTTTGCGAGATATGCGGGAGGGGGTTTATACAAGCTACGAATCTAGTAAACCACGTTAGGGTTCATACCAACGAATACCCTTTTAACTGTAGCGAATGCGGGCGCAAATTCAGGCAAGCCGAAAGACTACGGCTCCATGCGAAAAGGCATAAAGATGGGGCCGTTTCTACGGTCAAGGAGAAACGACAGATTGATGTGGAGAGACGAACGCATGTCTGTGAAGTCTGCAAAAAGGGATACGCTTCGAAAAGTGCGCTCAAGACACATTTACTAATTCACGGAGATAAGTTGTTTTTGTGCAGCGAGTGCGGGAAAGGTTTCGTAAGCAAACCTTTGTTAAGATCGCATTCTAAAATTCACTCGGGTGTTAAGCCGTACCACTGCGAGACGTGCGATCGTAACTTCTCTCATTACGTATCGCTCAAGGCTCATACACTGATTCACACGCGTGTTAAACCCCACAGGTGCTCGGTATGCGGTAAGATGTTCACCCAGAAACATCACTTGACGTACCACATGCGGACGCACTCGGGTGAAAGGCCGTTCGCTTGCAGTTACTGCGGGAAGACGTTCTCGTTGAACTGTAATCTGACGGTGCACATGAGGATACATTCGGGGGAGACGCCGTATGTCTGTGGTGTGTGTGGGAAAGGGTTCTACGATTCGAGTAGTTTGAAGAAACATAAGAAGGCGCACGGTGAGATgtag
Protein Sequence: MEINNYEKICRTCLREVPLQSVFTENPIEDDGNNVKHISDMLIECTSVKICKDDILPLNICSECINQLIQVYKFRKKCENNEKILEESRQYYNDSSNSDINDETDVCDTKHVKPKRHPMKRDHKCDICQKSFTTSQLKIHMRIHTKERPFTCSYCGQQFSLNCNLRRHVMLHTGEQPKRHGIDKQHTCEVCGQRFSFKCNLKRHAMRHTQERPHVCEICGRGFIQATNLVNHVRVHTNEYPFNCSECGRKFRQAERLRLHAKRHKDGAVSTVKEKRQIDVERRTHVCEVCKKGYASKSALKTHLLIHGDKLFLCSECGKGFVSKPLLRSHSKIHSGVKPYHCETCDRNFSHYVSLKAHTLIHTRVKPHRCSVCGKMFTQKHHLTYHMRTHSGERPFACSYCGKTFSLNCNLTVHMRIHSGETPYVCGVCGKGFYDSSSLKKHKKAHGEM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01343297;
90% Identity: iTF_01343297;
80% Identity: -