Slut012742.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Sialis lutaria
Gene Symbol
-
Assembly
GCA_949319165.1
Location
OX439240.1:8958166-8963695[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0035 0.19 12.5 1.6 1 23 143 165 143 165 0.98
2 16 5.8e-08 3.1e-06 27.5 1.3 1 23 169 191 169 191 0.99
3 16 2.4e-05 0.0013 19.3 2.0 1 23 197 219 197 219 0.97
4 16 0.00029 0.016 15.9 3.6 1 21 225 245 225 246 0.94
5 16 0.0014 0.074 13.8 0.0 1 23 253 275 253 275 0.94
6 16 0.051 2.8 8.8 0.1 1 23 411 433 411 433 0.97
7 16 1.8e-05 0.00099 19.7 5.2 1 23 439 461 439 461 0.98
8 16 0.0039 0.21 12.3 0.4 1 23 467 490 467 490 0.93
9 16 0.00045 0.024 15.3 1.2 1 23 496 519 496 519 0.92
10 16 0.00088 0.048 14.4 4.1 1 23 532 554 532 554 0.99
11 16 0.00012 0.0063 17.1 5.7 2 23 561 582 560 582 0.96
12 16 1.8e-06 0.0001 22.8 0.4 1 23 589 611 589 611 0.96
13 16 3e-06 0.00016 22.2 1.2 1 23 617 639 617 639 0.98
14 16 3.3e-06 0.00018 22.0 0.7 3 23 647 667 645 667 0.96
15 16 2.1e-05 0.0012 19.4 0.1 1 23 673 695 673 695 0.99
16 16 0.33 18 6.3 1.8 1 23 700 723 700 723 0.94

Sequence Information

Coding Sequence
atggaaaaatttGATTGTGATTTTAGTCGTATTTGCCGTGCTTGTAAAAAAGAAACAGACGAAATGTTTTCCGTTTTCGAACCGGACGCTGAAACAGGCGAACCAAATAAATTAGCAGAGATGTTAATGACGTGTACAACCGTACTGGTTGAAAGCGGTGACGGCCTTCCTAGTTCAATTTGTGAACCGTGTGCCACTCAGCTTGACAAtgctttcaaattcaaaaaacagTGCGAGATTACAGACGCGTCGTTACGTTTATATGTTCGGAAAAAACATATCAAAGAAGAGACGAACAACACGGAAGAAACGGGGGATGAAGTGCTCGACTTTGCATCACTGTACAACAGTGAAATATCACACATTGAAGATGTGAAACCCGAACCAACAGATCTCCTCGAAGTGATCAGCAAAGAATCCAGCATGTTCCCGTGTGACATGTGTAACAAACGGTTTCTCACGATGCGGCTATTGAAGTCACACAAGCGTGTCCACAGTATGTCATTCAAATGTAAAGTGTGCGACGAAGAGTTCACAAGATCGAACTTGCTTGAAAGACACATGAGAACGCACGGTTCACAAAAAGTACATGTGtgtaaaatatgtaacaaaacGTTGACAAAAATTGAACAGTTGAAGCGACACATGGCTACTCATGTAAAACATAAACCTTTCTCGTGTGAAAAGTGTAAAAAGTGTTTCAGCCGTGTCGACCATCTCGCAAATCATGCAAAGCGTTGTAAAGGGGGACGTCCATTTGTATGTAATATTTGTAACAAGGGGTTCATGAGAGAGGACGCAATGCAACTGCATGTAGCTGGACATGGGACTAACAAAGCGGTGTTAGAAACTATTGAAAATTACGAAGATCATTATATTCAGGTTGAAAATTATCCAAATTCAGATATGAACGAGAAAACCAGTGATTCAGATTATTTTGATGAAGGCGGCATGAATTCGAACACTGATGAAAAGAATAATTTGACTGATACTCCAATACAAGCAACTGCtgtatttaaaactgaagatTTAACACAGGAAGAGGGTGCAGCAGAAATGAacaatcatataaatagtatagccgATGATTCAGACGATGATGCAAAACCTCTATCCGAACGCGTAAACCAGAAACAGAAAAGTGATGACGATGTACCTATGAAAAGAAAACGTGGACGTCCTAGAAAAAGTGATTCACACTGTGTAGTACAAAAATCTAAAGTAGGAGAATTCCCTTGTGAACAATGTGGGGTTATCATGTCAACGCAAAGACGACTGGAGTTACATATAGAAAAACATTCAGATGGTGAAGCGTTTGAATGTAAAATCTGTAGAAAGAGATTCACACGAGCTATTCACTTAAAAAGACACTTCAGAAATCATGCAGACGATAAAGAGTTCCAGTGCGATCTGTGTTCAGAAATATTTGACAAGAGAGATGATTTAATCCAGCATAATACGAAGGAGCATCCGTCAGACGGTATGTTTGAATGTGATGTATGCTCGAAAGTATTTAATTACTTTACTAATCTGGAAAATCATAAAGCCCAGAAACACGGAGAAGTCGACGATAAATCTCCAGTTTTCAAGAAGTATAAGTGTCAGATATGTGAGAAGGCATTCACGACAGAGAAGTACTGTGAAACGCACATGAAGTCTCACAGCAATGAGCGTACGTGGAAATGCGAGACCTGTAGCAAGAAGTTCAAGACCAAGTCACACCTGACGGAGCACACGAAGTTCCACAGCGAGTGTGCCAGAAAGTACCTGTGCTCGGAGTGCGGCCAGAGGTTCATACGGAACGATTACCTTGTGATCCATATGCGCAGGCACCGGGGTGAGAAACCGTTCAAGTGCAAGTACTGCGGAAAAGGGTTCCCAAGGACTACGGATTTGACGGTACACGAACGGTACCATACGGGAGAGAAGACGCATCTTTGTATGGTTTGTGGAAGGGGCTTTGGAAGGGCATATAACTTAACGGTGCACATGCGCACGCACACGGGTGAGAAACCGTACCAGTGCACGTATTGTGACGCGGCGTTCGCACAGGGCAACGACCTGAAGGCGCACGTGCGTCGTCACACCGGCGAACGGTACCACTGTGATCTGTGCCCCGAGGCTTTCCTCATGGGCTACCTGCTGACGCACCACAAACGGACCGTGCACGGCGTCGACGTCCGCTCACACATACGCAGGCTCCATCCGCACGAGAAGGTGCAGCCCGGCGCTCCGCCACCGACGGCGCCTTTGCTTCCGCTTATCGCATCACTGCCGAACGTGTTGCCGATCCCGCACGCGCTCGTCCAGCCCGAGATTAAGCTCGAGCAACCGACTGCGCCCATGCCGATGCTGTCTGCCGATTCATGA
Protein Sequence
MEKFDCDFSRICRACKKETDEMFSVFEPDAETGEPNKLAEMLMTCTTVLVESGDGLPSSICEPCATQLDNAFKFKKQCEITDASLRLYVRKKHIKEETNNTEETGDEVLDFASLYNSEISHIEDVKPEPTDLLEVISKESSMFPCDMCNKRFLTMRLLKSHKRVHSMSFKCKVCDEEFTRSNLLERHMRTHGSQKVHVCKICNKTLTKIEQLKRHMATHVKHKPFSCEKCKKCFSRVDHLANHAKRCKGGRPFVCNICNKGFMREDAMQLHVAGHGTNKAVLETIENYEDHYIQVENYPNSDMNEKTSDSDYFDEGGMNSNTDEKNNLTDTPIQATAVFKTEDLTQEEGAAEMNNHINSIADDSDDDAKPLSERVNQKQKSDDDVPMKRKRGRPRKSDSHCVVQKSKVGEFPCEQCGVIMSTQRRLELHIEKHSDGEAFECKICRKRFTRAIHLKRHFRNHADDKEFQCDLCSEIFDKRDDLIQHNTKEHPSDGMFECDVCSKVFNYFTNLENHKAQKHGEVDDKSPVFKKYKCQICEKAFTTEKYCETHMKSHSNERTWKCETCSKKFKTKSHLTEHTKFHSECARKYLCSECGQRFIRNDYLVIHMRRHRGEKPFKCKYCGKGFPRTTDLTVHERYHTGEKTHLCMVCGRGFGRAYNLTVHMRTHTGEKPYQCTYCDAAFAQGNDLKAHVRRHTGERYHCDLCPEAFLMGYLLTHHKRTVHGVDVRSHIRRLHPHEKVQPGAPPPTAPLLPLIASLPNVLPIPHALVQPEIKLEQPTAPMPMLSADS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01343283;
90% Identity
iTF_01343283;
80% Identity
-