Basic Information

Insect: Sialis lutaria
Gene Symbol: -
Assembly: GCA_949319165.1
Location: OX439238.1:3866093-3868104[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.067 3.6 8.5 3.0 1 20 77 96 77 98 0.88

2 15 9.7e-06 0.00053 20.5 1.0 1 23 108 130 108 130 0.98

3 15 0.0014 0.075 13.8 6.7 1 23 194 216 194 216 0.97

4 15 5.5e-07 3e-05 24.5 0.8 1 23 260 282 260 282 0.98

5 15 0.022 1.2 10.0 2.2 1 23 289 312 289 312 0.89

6 15 0.33 18 6.3 4.2 1 23 313 335 313 335 0.93

7 15 0.0002 0.011 16.4 5.5 1 23 340 362 340 362 0.96

8 15 0.0004 0.022 15.5 0.1 1 23 370 392 370 392 0.96

9 15 1.4e-06 7.6e-05 23.2 2.0 3 23 400 420 398 420 0.96

10 15 3e-05 0.0016 19.0 1.4 3 23 428 448 426 448 0.96

11 15 1e-06 5.6e-05 23.6 0.2 1 23 454 476 454 476 0.98

12 15 3.8e-05 0.0021 18.7 3.2 2 23 483 504 482 504 0.98

13 15 1.8e-06 9.9e-05 22.8 1.2 1 23 510 532 510 532 0.99

14 15 1.7e-06 9e-05 22.9 0.1 1 23 538 560 538 560 0.98

15 15 5.8e-08 3.1e-06 27.5 2.0 1 23 566 588 566 588 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.067	3.6	8.5	3.0	1	20	77	96	77	98	0.88
2	15	9.7e-06	0.00053	20.5	1.0	1	23	108	130	108	130	0.98
3	15	0.0014	0.075	13.8	6.7	1	23	194	216	194	216	0.97
4	15	5.5e-07	3e-05	24.5	0.8	1	23	260	282	260	282	0.98
5	15	0.022	1.2	10.0	2.2	1	23	289	312	289	312	0.89
6	15	0.33	18	6.3	4.2	1	23	313	335	313	335	0.93
7	15	0.0002	0.011	16.4	5.5	1	23	340	362	340	362	0.96
8	15	0.0004	0.022	15.5	0.1	1	23	370	392	370	392	0.96
9	15	1.4e-06	7.6e-05	23.2	2.0	3	23	400	420	398	420	0.96
10	15	3e-05	0.0016	19.0	1.4	3	23	428	448	426	448	0.96
11	15	1e-06	5.6e-05	23.6	0.2	1	23	454	476	454	476	0.98
12	15	3.8e-05	0.0021	18.7	3.2	2	23	483	504	482	504	0.98
13	15	1.8e-06	9.9e-05	22.8	1.2	1	23	510	532	510	532	0.99
14	15	1.7e-06	9e-05	22.9	0.1	1	23	538	560	538	560	0.98
15	15	5.8e-08	3.1e-06	27.5	2.0	1	23	566	588	566	588	0.99

Sequence Information

Coding Sequence: ATGAATGATgaaatgaaaattgaaaatttgataacaagtaaTGGATCATCTGATTTTCTATCAGCTGTAAAAAATGAAGATTTCTTACTCAATGATACAAAAACCGATATGAAAGTTGAAGAAACAAACTCAAACATAACTACAGATATTATTAGTGATAATTTAGACTTAGTACAAGAAGACTCGAAAGATTGTGATTTCTCTGACAGCAAGAACAGTTCTTTAAAATATTCTTGCGATTTCTGTGAAAAAAGGTTCAAACATAAAAAGAGTGTCCCGAGacataaaaaactatgctattCTAAAAACAACAAAACTTTATTTCCATgtgaattttgtaataaaacattttacgaTCAAGAGACCTTATCTATTCATTTACGACAGCATAAACGAAAATTAAGAAGTACAACGATTGCTGAAAAAAATGAATCTCTGAATACGAAACTTATAAATGAGAAAATATCAACGATATACGCGAAACGTGTAACAGAGGTTGTCTATTCTTCCGATAGCGATTGCGaatatgaaataatacaaacaatTAGAAAAATAGATAGCAATAAAGTTGATTCTTTTCACGTTTGTTACGTATGCCATAAGAGTTTTACAAAAGTGAATAGTTATAATcaacatatgaaaaaacataGTGCCATTGAATCAGAGTCTGATAAAAATAACAGTTCTGATGATGACAGAGGGCTTGAAGATTCATTTGAATGTACTGACATTAGAGACGTATCTGAAAATGAATCTAAAAAGGAGCCTAGCGAGAAATACCCTTGTGAACATTGTGATAAGTCGTTTTCTAGAGTTGCATCTTTGGCAAATCATGTGAAAACTCATAATAATCCTAAACTAGCACATGCttgtgatttttgtaatgaATTATTTAGgtACATGTCCAACCTATCCAAACACCTATTTGATCAGCACCACTTCTGTAACATTTGCAATAAAACCTGCGACGAAAACATCACCTATAGACAGCACTCAGAAATACACAAATCAGATGAGTATCTTTGCACCCACTGTTCGCAAAAGTTCACTTCAAAGATAAAACTACAGCAGCACATGAAGAAGCATTCAAGCAAAACTATATACAAGTTCTCGTGTAACGTCTGTGGTAAAATACTCCAGTCACCCAAGTCGTACAAAGCCCACATGGCTGCACACGCTGGACTCAGAGCTCACCTTTGTACAATCTGTGGTAAAGGGTTCTCATACTCGAGCCAGCTGAGCATGCATATGAGGAATCATTTAGGATACAAACCTCATCTTTGCAGTTTCTGTGGGAAAGCGTTCACCGTCCGACGATATTTAATCGTGCATCAACGAATCCACACTCAAGAGAGGCCGTTTGTATGTGAAGTGTGTAACAAAGGGTTCAAGGAGAAGCCAAATCTCATAGAACATATTCGGACACACACTGGCGAGAAACCGAATAAGTGTAAGCACTGTGGTAAGGGCTTTGCGCACTTGACCGGGCTTCGGCAACATCTGCAGATACATGATGGGATTAAGAAGTTTACTTGTAACGTATGTGGTAAAGGGTTCATACAGGGTGGACATTACCGTGAACACATGCGGACTCATTCTGGGGAAAAGCCGTACGTTTGCCCTAAGTGCGGTAAGGGTTTTGGGAATAGCAGTACGCTAGCCGTCCATAGCAGAATTCATAGCGGTGATAGACCTTATAAATGCAACACTTGCGGGAAGAGCTTCATCAAAAATTACGGCCTCAAACAGCACATCAGAACTCATAAACCTTGTAATGTTGGCCAACAGAGTTAG
Protein Sequence: MNDEMKIENLITSNGSSDFLSAVKNEDFLLNDTKTDMKVEETNSNITTDIISDNLDLVQEDSKDCDFSDSKNSSLKYSCDFCEKRFKHKKSVPRHKKLCYSKNNKTLFPCEFCNKTFYDQETLSIHLRQHKRKLRSTTIAEKNESLNTKLINEKISTIYAKRVTEVVYSSDSDCEYEIIQTIRKIDSNKVDSFHVCYVCHKSFTKVNSYNQHMKKHSAIESESDKNNSSDDDRGLEDSFECTDIRDVSENESKKEPSEKYPCEHCDKSFSRVASLANHVKTHNNPKLAHACDFCNELFRYMSNLSKHLFDQHHFCNICNKTCDENITYRQHSEIHKSDEYLCTHCSQKFTSKIKLQQHMKKHSSKTIYKFSCNVCGKILQSPKSYKAHMAAHAGLRAHLCTICGKGFSYSSQLSMHMRNHLGYKPHLCSFCGKAFTVRRYLIVHQRIHTQERPFVCEVCNKGFKEKPNLIEHIRTHTGEKPNKCKHCGKGFAHLTGLRQHLQIHDGIKKFTCNVCGKGFIQGGHYREHMRTHSGEKPYVCPKCGKGFGNSSTLAVHSRIHSGDRPYKCNTCGKSFIKNYGLKQHIRTHKPCNVGQQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01343279;
90% Identity: iTF_01343279;
80% Identity: -