Slut007201.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Sialis lutaria
Gene Symbol
dre4
Assembly
GCA_949319165.1
Location
OX439235.1:25134809-25153671[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.00044 0.024 15.3 5.7 1 23 1260 1282 1260 1282 0.98
2 26 0.013 0.71 10.7 1.8 1 23 1288 1310 1288 1310 0.98
3 26 7.6e-05 0.0041 17.7 1.1 1 23 1316 1338 1316 1338 0.99
4 26 1.6e-05 0.00084 19.9 3.2 1 23 1344 1366 1344 1367 0.96
5 26 0.045 2.4 9.0 1.7 3 23 1377 1397 1375 1398 0.94
6 26 0.0066 0.36 11.6 1.0 2 23 1559 1582 1558 1582 0.91
7 26 2.8e-06 0.00015 22.2 0.2 3 23 1584 1604 1582 1604 0.96
8 26 0.00062 0.034 14.9 0.4 1 23 1610 1633 1610 1633 0.98
9 26 0.00027 0.015 16.0 4.8 1 23 1639 1661 1639 1661 0.98
10 26 1.4e-06 7.6e-05 23.2 1.5 1 23 1666 1688 1666 1688 0.98
11 26 1.8e-05 0.00096 19.7 3.0 1 23 1694 1716 1694 1716 0.98
12 26 0.0002 0.011 16.4 0.0 1 23 1722 1744 1722 1744 0.98
13 26 6.5e-07 3.5e-05 24.2 3.2 1 23 1750 1772 1750 1772 0.99
14 26 2.2e-05 0.0012 19.4 0.1 1 23 1778 1800 1778 1800 0.98
15 26 3.1e-06 0.00017 22.1 0.5 1 23 1806 1828 1806 1828 0.97
16 26 0.43 23 5.9 0.0 8 23 1832 1847 1831 1847 0.94
17 26 0.0013 0.072 13.8 2.3 1 23 1853 1876 1853 1876 0.98
18 26 0.00025 0.013 16.1 0.8 1 23 1881 1903 1881 1903 0.98
19 26 1.5e-07 8.4e-06 26.2 0.9 1 23 1909 1931 1909 1931 0.96
20 26 1.5e-05 0.00084 19.9 2.9 1 23 1937 1959 1937 1959 0.99
21 26 1.3e-05 0.0007 20.1 0.8 1 23 1965 1987 1965 1987 0.98
22 26 7.8e-05 0.0043 17.7 0.3 1 23 1996 2018 1996 2018 0.98
23 26 1e-06 5.7e-05 23.6 0.8 2 23 2025 2046 2024 2046 0.96
24 26 0.00024 0.013 16.2 0.5 1 23 2052 2074 2052 2074 0.98
25 26 2.5e-05 0.0013 19.3 1.5 1 23 2080 2102 2080 2102 0.99
26 26 7.7e-07 4.1e-05 24.0 1.3 1 23 2108 2130 2108 2130 0.99

Sequence Information

Coding Sequence
ATGGCAAACATAAGTGTTGataaagatacattttttcGTCGTATGAAAAGGTTATATTCAGCATGGAAGaaTGCTGAAGATAACGGGGATGATGGTTTTGCAAAAATGGATTGTCTGGTGTCTGCAGTGGGTGTTGATGAAGAAGTGGTTTACAGTAAATCTGCTGCGTTACAGACGTGGCTTCTTGGATACGAACTGACAGATACGATAATGGTATTGAGTGTAGACACAATTCATTTTTTAGCAAGTAAAAAGAAAATCGAATTTATGCGTCAAGTGGAAAATATTAAAGACGAAGATGGTATCCCGCCAGTAAAATTACTTGTTAGAGATAGAAATGACAAagataaagaaaattttaagaaattaatCAGTATTATAAAAGCGAGTAAGAAAGGAAAAACTCTAGGTGTTTTTTCAAAAGATAATTATCCTGGAGAATTTATGGAATCATGGAGAGCTGTTTTGAAAGGAGAAAATTTCTCTACGATTGACGTAAGTTCATCAGCCGCTTTAGTAATGAGTCCAAAAGACGATGCTGAGATTCTAACCATCAAAAAGGCATGTCTCGTATCAGTTGATgtttttactaaatatcttaAGGATCAGATCATGGAAATTATTGATTCAGATAAAAAAGTAAAACATTACAAACTTGCTGAAGGTGTCGAACAAGCTATTACAGATAAAAAATACGTATCTGGTGTAGATACAAGTCAAGTTGATATGTGTTACCCTGCCATCATCCAATCCGGTGGAAACTTCAATCTTAAATTTAGTGTAGTCAGTGATAAGAACGTTTTACATTTCGGTGCGATTATCTGTTCTCTTGGTGCAAGATACAAATCGTATTGTTCTAATATCGTACGCACACTGTTAGTGAATCCGTCTAATGAGGTACAAGATAACTATAATTTCCTGCTGACTGTCGAAGAGGAATTACTGAAGAATTTGGTCGCTGGAAAAAAGTTATCGGAAGTTTATGACTCTGGATTTAATTTTGCCAAGAAAGAAAAGCCAGCGTTAGTTGAACACCTGACAAAATCATTTGGatttGCGATGGGTATTGAATTTCGAGAAAGCTCTCTTCTTATTGGTCAAAAAACAACAACAGTGTTGAAAAAGGGAATGGTTTTCAATGTAAACGTAGGATTATCAGGTCTTCATAACAAAGACGCTACTGATAAAGAAGGAAAAACCTATGCCTTATTCGTCGGTGATACTGTTATGGTGAACGAAGACGCACCAGCAACAATTTTAACAGTATCAAAAAAGAAAATGAAGAATATCggtatttttttgaaagatGAAGAGGATGAAGAAGAGGAGCAAGAGAATGAAAAGAAGAAACCTAAACCTGAAATTCTCGGTAGAGGTAAACGAACAGCTGTTATTGAATCTAAACTTCGATCTGAACATTCATCCGAAGAGAAACGTAAAGAACATCAAAAAGAATTAGCTGCGCAACTTAACGAGAAAGCAAAAGAACGTCTTGCTAAACAATCAGGCGGGAAAGAAACGGAAAAAGTTCGAAAGTCAACAGTTTCGTATAAAAGTCTTAATCAGATGCCTCGTGAACCTGAAGTTAAAGAACTTAAACTTTACGTCGaTCGTAAATACGAGACTGTCATATTACCAGTATTCGGAATCCCCGTTCCTTTCCATATTtcaacaatcaaaaatatttcacaatCGGTTGAAGGTGATTATACGTACTTACGTATTAATTTCTTCCATCCTGGAGCAACTATGGGTCGAAATGAAGGTGGAATGTATCCACAACCTGACGCGACTTTTGTTAAAGaagtTACTTATCGGAGTACAAATATTAAAGAACCTGGGGAAATATCACCTCCATCATCAAATTTGAATACAGCGTTCCGATTAATTAAAGAAGTTCAAAAGAAATTCAAAAATAGGGAAGCAGAAGAACGTGAAAAGGAAGATTTGGTTAAACAAGATACGTTGGTTTTATCACAGAATAAAGGAAATCCTAAATTGAAGGATTTGTATATTAGACCGAATATTGTTACGAAAAGAATGACAGGGTCACTAGAAGCACACAATAATGGTTTTAGATACACGTCAGTGCGAGGCGACAAAGTAGATATACtgtacaataatattaaaaacgcTTTCTTCCAACCGTGCGATGGCGAAATGATAATCCTTCTACATTTCCATCTCAAGCATGCTATTATGTTTGGGAAGAAGAAACACGTAGATGTACAATTTTATACTGAAGTCGGTGAAATTACAACAGATTTAGGTAAACATCAACACATGCACGATAGGGATGACTTGGCAGCTGAGCAATCTGAACGTGAGCTACGGCACAAACTTAAAACCGCTTTCAAGAGTTTTTGTGAAAAAGTAGAAGGTATGACAAAGCAAGAAATTGAATTTGATACACCATTCCGTGAATTGGGATTCCCTGGAGCGCCATTCCGTTCTACTGTCTTGTTACAACCGACCAGTGGATGTTTGGTGAACTTAACTGAGTGGCCACCATTTGTGATAACGCTTGAAGATGTGGAACTGGTTCATTTTGAGAGAGTGCAGTTCCATCTGAAGAACTTTGATATGATATTCGTGTTTAAAGATTATGCTAAGAAGGTGGCAATGGTTAATGCTATTCCGATGAACATGCTGGATCACGTCAAGGAATGGTTAAAttcgtGCGATATTCGGTACTCGGAAGGTATACAGTCTTTGAATTGGACTAAGATTATGAAGACTATTACTGATGATCCGGATGGATTCTTTGAAAGCGGCGGGTGGACTTTCTTAGACCCAGAGAGTGATGTTGAAGCTGCAGACGAAGATGACGATGATGAGGATGAAGATGAAGCATACGAGCCGACCGATGCTGACAGTAACCTGGAGGAATCAGATGATGATTCGGAATATTCAGAGGGAGAGACTGAAGGGGATGATAGTGATAGTGAAGAAGAATTAGGTACCGATGAAGAATCTGGAAAAGATTGGTCTGATTTAGAACGTGAGGCTGCAGAAGAAGACAAAGAAAGAAATTATGAAGTTGAAGATTatgcaaacaaaaataaaacacgtGGTAGAGATTTTGATAGGGACAGACATTCTTCAAAGGGAAACAGTAAACATAATTCAAATCATAAAAGCAAATCTCATTCTCATGATAAGCACAgAACGGATAATAAACGAAAGAGTTCTTCAAATCACAGAAAAGTGTCTAAAACAAAACCAAGCTCATCTAGAAGTTCATCCCATCATAGTAAAAATCATAGTTCATCGTCTTCAAGACATAGCCCATCAAAGAATAGAGATAAACATCATAAGAGTTCTTCAAACGATAGGAAACGGTCTAGAGATGATAGCGGTGATCGGCATCGAAGCAGTAAAAAATCAagACTCTGTTTATCCAGTGAAGAAGAAAcattaaagatatttttaaatgatggTGATGATAAGaatattcaaatttttgatttattgaaAGAATGTTGTCCATTTATTGAGgtacaGCAAAATGATAATTTACCTTCTAACATTTGCATGATGTGTTTAACacaattaaatttactttatcGTTTTCAACAACGGTGTATTGCTTCTGATACTAAGTTACGTCAATATTCATTACAAAAGAACTCGTACGAATGGGTTTCACATTTTGCTGAATGTTCATCAGCAGAAAATCTCAATAATACTCAACCCCCTTCTGAatcaaatgaaataattaacacTGATGAAAATAAAACCCCTATAAAAATATCTGAAGCCAAAGAGAACAAACAGTTCATGTGTAATATCTGTAGTCACTGTTTTCCACGTAGAGAAACTTTGGTACGCCATAAAAGAACTCACACTGCTGAAAAACAGTATAACTGTACTGTTTGCCAGAAAAAACTAGCATCGGCAACTTCATTATCgcatcataaaaatattcatacaggTCAAAAACCTTTCCAGTGTAAATTTTGCAGTAAAGCTTACGGAGATCCAAGTTCTTTGCGCTTACATTTGAAACGCCACTTGAATCAACGAGATTACAAATGTTCGGAATGTAACTATTCTTTCTTTCGAAATTACGAACTAAAAAATCATATCATAATACATCATCGAACTAAACCAGAAGAGAAATTTGGTTGCGGTTTTTGTAATAAAGAATTTAGTAACCCGATTTCTCAGCAGAGACACGAGAAGTTACACCATTtaaagaaaactaatatttgtgTGATATGTAATAGAGATGaacctaataaaatatttataaattcttgTCGTACATGTTTATCGACTGAAGGAATGATGTCACATATTTCAACAAAAGGGGTAAAGTCAATTCCATTATTAGATATGATAATGGCATGTGCTTCCGTTACGATTGAAGAAGGAGATGGGTTTCCCCAACAAGTTTGTGAAGAATGTATTTTGCTATTAAATAAATCATACATATTTCGTCAGATTTGTCAAAGATCTGATCAGTTACTTCGTAAACAACTAAACGATGTTCCTACAGATAAAGATTCCGAAGATGACAACAATTCTGAAATACACCAGGACTACTCAACTGATACAGAATCAAAGGTTAATGAAAAATGTGATATAATAAGTAACGAAAAAACACCGCCAACGACATTGACAGAAAACAAAGCAGAACAGcaagttgaaaatattgaaaatttagatGTAGAATGTGAAAGATGTAATAGTAGGTTTTCTTCTATAAGTAAtctaaatACCCACACAAGAATCATTTCTCACTTGTGTTCAGAATGTGGTAAAGGATTTATACGCTCCAGCGACTTGAACCAGCACGTGCGAATACATACCGGTGAAAGACCTTACGTATGCCATCTGTGTCCGAACAAGGCATTCACGCAAGCTGGCCAGTTGAGGGAACATCTGAGGGCACACGAAGATAAGAAAGACTTTGTTTGCTCTACCTGTGGGAAGGCATTTTCACGCTTCAATACTTTATGCCATCATGTGAAAATACATACAGGAAAAATGCATACGTGTAATATTTGTGGGAAGAGTCTTTCAAGTACATCTTCTTTGAAAGTCCACATGCGAATCCACACGAAAGAAAAACAGTACATCTGTCCTATATGCAGCAAAGCCTTCACCCACCTGACTCACTTAAAAGTGCACACTCGCCTCCACACAGGCGAACGCCCATACATCTGCTCTGTCTGCCCGAAGGGATTTGCTGACGAATCCCGTTTACGTGTCCACGCTCGTATCCACTCTGGAGATAGACCGTACAAATGCACGATTTGTGACAGAAGCTGCGTCACATCCTCTATGCTAAAGAAACACATGAGGATTCACAGTGGGGAGAAGCCCTACGTCTGTTCTGTGTGCCCAAAGGCGTATCCAAGATCGGAAGACTTGAGGGTGCACGAGAAAACCCATACAGGGAATAGAAACCACGTGTGTGGCGTATGTGGTAAGGGGTTCTATCAAGCATCTACTCTTAAGGTGCATCAAAGGATTCACAGTGGAGAGAAGCCGTTTGCATATTATGATGAACTGAACACGCACATGAAATCCCACTGCAACAAAACTCCCTACACGTGTACCACATGCTCTCAAACATTCTCCCAGCTTCGAACCTACTTAGATCACCAACGTTCCGAACACGGAGAACGtccttttaaatgcaacatcTGTTCAAAAGCGTTCTTCTATCGTAGCGGTCTTGTATCTCATACGCTCGTCCACACTGGAGAAAAACATTACCTCTGCAATGAATGTGGTAAAAAATTCACTCGTAACGACGAGTTACGTAGACATGTTCGGATACATACGAAAGAGAGACCGTATGTTTGTAGGATATGTTCTCGAGGGTTCACGCAGTCATTTCACTTGACTGAACACATGAGGTCTCATGGGACTGAAAAGTTGTTTGTATGCAGTACGTGCGGTATGAAGTTTGCAAGAAATGGATCGTGGAGGACTCATATGAAGACACATTTGGCGCCAAGTGCCAGGAAGGTTTATCCTTGCCAAGTTTGCAATAAGTCATTTATGTTAGCAGGTACATTAAAAAAGCACATGACCATTCACACAGGCGAAAGACGTTGGATCTGTGAAATATGTGGCAAGCGATTCACACAATCAGCACATTTAGAAATACACCGTAGAAGCCATACTGGTGTACGACCTTTTGTATGTGACACTTGTGGTCGGGGATTTTCTGCTTCATCCAGACTTACGATACACAAGAGATCCCATACGGGTGAGAAACCATACCGTTGTACATTGTGTCCACAAGCCTGCGCTACGTCAACTGCGTTGAAAAAACATATAAGAACGCACACAGGCGAAGCTCCTTACCAATGTAATTTGTGTGATAAAGCATTCAGAAGAAGGGATTTGTTAAAGTTACATCAAAAAGtacatgtaaaaaatgttttgtga
Protein Sequence
MANISVDKDTFFRRMKRLYSAWKNAEDNGDDGFAKMDCLVSAVGVDEEVVYSKSAALQTWLLGYELTDTIMVLSVDTIHFLASKKKIEFMRQVENIKDEDGIPPVKLLVRDRNDKDKENFKKLISIIKASKKGKTLGVFSKDNYPGEFMESWRAVLKGENFSTIDVSSSAALVMSPKDDAEILTIKKACLVSVDVFTKYLKDQIMEIIDSDKKVKHYKLAEGVEQAITDKKYVSGVDTSQVDMCYPAIIQSGGNFNLKFSVVSDKNVLHFGAIICSLGARYKSYCSNIVRTLLVNPSNEVQDNYNFLLTVEEELLKNLVAGKKLSEVYDSGFNFAKKEKPALVEHLTKSFGFAMGIEFRESSLLIGQKTTTVLKKGMVFNVNVGLSGLHNKDATDKEGKTYALFVGDTVMVNEDAPATILTVSKKKMKNIGIFLKDEEDEEEEQENEKKKPKPEILGRGKRTAVIESKLRSEHSSEEKRKEHQKELAAQLNEKAKERLAKQSGGKETEKVRKSTVSYKSLNQMPREPEVKELKLYVDRKYETVILPVFGIPVPFHISTIKNISQSVEGDYTYLRINFFHPGATMGRNEGGMYPQPDATFVKEVTYRSTNIKEPGEISPPSSNLNTAFRLIKEVQKKFKNREAEEREKEDLVKQDTLVLSQNKGNPKLKDLYIRPNIVTKRMTGSLEAHNNGFRYTSVRGDKVDILYNNIKNAFFQPCDGEMIILLHFHLKHAIMFGKKKHVDVQFYTEVGEITTDLGKHQHMHDRDDLAAEQSERELRHKLKTAFKSFCEKVEGMTKQEIEFDTPFRELGFPGAPFRSTVLLQPTSGCLVNLTEWPPFVITLEDVELVHFERVQFHLKNFDMIFVFKDYAKKVAMVNAIPMNMLDHVKEWLNSCDIRYSEGIQSLNWTKIMKTITDDPDGFFESGGWTFLDPESDVEAADEDDDDEDEDEAYEPTDADSNLEESDDDSEYSEGETEGDDSDSEEELGTDEESGKDWSDLEREAAEEDKERNYEVEDYANKNKTRGRDFDRDRHSSKGNSKHNSNHKSKSHSHDKHRTDNKRKSSSNHRKVSKTKPSSSRSSSHHSKNHSSSSSRHSPSKNRDKHHKSSSNDRKRSRDDSGDRHRSSKKSRLCLSSEEETLKIFLNDGDDKNIQIFDLLKECCPFIEVQQNDNLPSNICMMCLTQLNLLYRFQQRCIASDTKLRQYSLQKNSYEWVSHFAECSSAENLNNTQPPSESNEIINTDENKTPIKISEAKENKQFMCNICSHCFPRRETLVRHKRTHTAEKQYNCTVCQKKLASATSLSHHKNIHTGQKPFQCKFCSKAYGDPSSLRLHLKRHLNQRDYKCSECNYSFFRNYELKNHIIIHHRTKPEEKFGCGFCNKEFSNPISQQRHEKLHHLKKTNICVICNRDEPNKIFINSCRTCLSTEGMMSHISTKGVKSIPLLDMIMACASVTIEEGDGFPQQVCEECILLLNKSYIFRQICQRSDQLLRKQLNDVPTDKDSEDDNNSEIHQDYSTDTESKVNEKCDIISNEKTPPTTLTENKAEQQVENIENLDVECERCNSRFSSISNLNTHTRIISHLCSECGKGFIRSSDLNQHVRIHTGERPYVCHLCPNKAFTQAGQLREHLRAHEDKKDFVCSTCGKAFSRFNTLCHHVKIHTGKMHTCNICGKSLSSTSSLKVHMRIHTKEKQYICPICSKAFTHLTHLKVHTRLHTGERPYICSVCPKGFADESRLRVHARIHSGDRPYKCTICDRSCVTSSMLKKHMRIHSGEKPYVCSVCPKAYPRSEDLRVHEKTHTGNRNHVCGVCGKGFYQASTLKVHQRIHSGEKPFAYYDELNTHMKSHCNKTPYTCTTCSQTFSQLRTYLDHQRSEHGERPFKCNICSKAFFYRSGLVSHTLVHTGEKHYLCNECGKKFTRNDELRRHVRIHTKERPYVCRICSRGFTQSFHLTEHMRSHGTEKLFVCSTCGMKFARNGSWRTHMKTHLAPSARKVYPCQVCNKSFMLAGTLKKHMTIHTGERRWICEICGKRFTQSAHLEIHRRSHTGVRPFVCDTCGRGFSASSRLTIHKRSHTGEKPYRCTLCPQACATSTALKKHIRTHTGEAPYQCNLCDKAFRRRDLLKLHQKVHVKNVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-