Basic Information

Insect: Sialis fuliginosa
Gene Symbol: RGM1
Assembly: GCA_961205875.1
Location: OY540814.1:7163109-7165643[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 6.7 3.6e+02 2.1 0.7 1 21 14 34 14 35 0.91

2 12 0.24 13 6.6 0.6 3 23 311 333 309 333 0.91

3 12 7.7 4.1e+02 1.9 4.5 1 22 484 505 484 508 0.90

4 12 0.21 11 6.8 2.8 2 19 530 547 529 553 0.94

5 12 0.0019 0.1 13.2 1.2 1 23 568 591 568 591 0.97

6 12 0.032 1.7 9.4 0.8 1 23 596 620 596 620 0.92

7 12 0.36 20 6.1 2.4 3 23 642 663 641 663 0.93

8 12 0.004 0.21 12.2 0.1 1 22 668 689 668 689 0.95

9 12 0.2 11 6.9 1.2 1 17 706 722 706 728 0.89

10 12 0.0011 0.06 14.0 3.0 1 23 745 766 745 766 0.98

11 12 0.00025 0.013 16.0 1.5 1 23 772 795 772 795 0.96

12 12 2.1 1.2e+02 3.6 0.3 1 13 813 825 813 825 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	6.7	3.6e+02	2.1	0.7	1	21	14	34	14	35	0.91
2	12	0.24	13	6.6	0.6	3	23	311	333	309	333	0.91
3	12	7.7	4.1e+02	1.9	4.5	1	22	484	505	484	508	0.90
4	12	0.21	11	6.8	2.8	2	19	530	547	529	553	0.94
5	12	0.0019	0.1	13.2	1.2	1	23	568	591	568	591	0.97
6	12	0.032	1.7	9.4	0.8	1	23	596	620	596	620	0.92
7	12	0.36	20	6.1	2.4	3	23	642	663	641	663	0.93
8	12	0.004	0.21	12.2	0.1	1	22	668	689	668	689	0.95
9	12	0.2	11	6.9	1.2	1	17	706	722	706	728	0.89
10	12	0.0011	0.06	14.0	3.0	1	23	745	766	745	766	0.98
11	12	0.00025	0.013	16.0	1.5	1	23	772	795	772	795	0.96
12	12	2.1	1.2e+02	3.6	0.3	1	13	813	825	813	825	0.88

Sequence Information

Coding Sequence: ATGGATCTTTCTAACGACCTTGAAGACGACGATGACACCCACATATGTCTTAAATGTCACACAACAATCATTGGTCTTGACAACTACGTTTCCCACAGAAAAAACGTTCGTTGCAAACGCAAAATTACCGAAACATTAAAATCCGAAATATCCATAGATCCCGTTGTACCAACAGAGTTACCAGAATATCCTCTTCGAGccgatgattttttttcatcactTGAATTGCAAAGTAGTGCAAAAATCGCTCCTTCACCTCGACCTCCGCCCGGAATTTTAACCAGAAGTAAAACGTCTGCAGCTATATTAGCTAACAGTTCTCAAAAGGAACTAAATGAACGTGGAAATGAATGGATTGGTGGACATCAACTCAAAGTATCGGGTAGTGACAATCATGCGAAGCTTATCAAAGCTGTAGATAATATTAGTGGAAACACTATACATAAAAAAGAAAttcatagtacttatcaataTGATCTTGatgttgataattttaaaaatgaaattgattCTAATGACGATTATGATGACGATGAAGATGAAGAAGATGAAGATGAAGATGTTCCACCAAGAACTCACACAGGAGGTAAATGGAAGCCTAGGTCATCTCCAATACAATGGTCTGGGCCATCAAGTTCCCATGTTCAAAGTCATGATGATCTAGTTGGAAACGATTGGTATCAAAATCCCCCACCTTCATTCACAGGAGGTAAGTGGAAACCTTCTTTGTTAGGGCCAGCTCCTATAGCACCTAGAAGATATGATCAAGATGAAAATAATGAACTGTCAGAAGatgatgaaaatgaaaataaaaacactgcaccTCCGCCATATCATACTAAAGGAAAATGGATACCAGGACGACAAAATGAGCAAATGAGAAAATCATATAGCCAAGAAAAGGAAATGCCTAGTATGTTACAATACTGGTGTGGGTTATGCAATAGAATGTTAGCTTCCAAAACTTTTTATGAGCGTCATTTAAAATCAAATCTGCATAGAAAAAGatgtaaaaaagaaaatgaacTAGATTCAATGTATTTTGAACATGCGGAGAAAGAAGTGAGACCTAAAAGAACAAGGAAAGCTCCTAAAATGTTTGATGAAGATATTTGGGATACCGATTACACAAagacaaaaaagaaaaatgaaaatatagattttactGAAATAAGAAAAGTTGATCCGATTATAAAATGCGATGTGTGCCGGGCTAAAGTTCATTTGCATTTAATTGGAAAACACTTAATATCACATTTTCATTGCAGGAAAGGAGATCGCAATCATCCTATGGCTATGAAAATGGTTTTAGATAACATTCATAGTGTAGTTTTTCAATCACCATTTCAATGCCATCCATGTAGATTCTATTGTAACACTCAAAACACATTTATGATGCATTGGAGTTCTGAATCCCACCTGAATTGTGTCGAGAAAACTGAAGGAATATATTCGTGTacattttgcaattttgaatGTGAGTCAACATTTCATATGTTTGATCATTTACAAAGTGAAGCGCATCAAGAAGTAGTTTCTGTGATTAACAGATCTATGCCAATAGTAATACACAAAAGATCTATTTTACATTGTAATGTATGTTCGCAACAGTTTCGATATAATATTCAGTTGAAGCAACATTGTATAAAAGAAGGCCATGTCGATCACCAACACGTAGCTGGAAAGATAACCCAGCAGAAGTTTGAATGTTCCGAATGTAAATCTGTTTTTGGAAGAGCTATCGCTCTTCAAAAACACTTACATAAACGTCATTCCGTTCTGACTTATGTATGTTATATCTGTTCATTGAATTTTGAAACTTCTAAAGCTGCGAAGAAACATAGATCGACATTAACTCATAAATATAATGCTATTCTTAAAAGAATTGAAAAAGGGTTGCCTGTGGAAGATCCTTCAAGAAACTGCATGTTCTGTTCTAAGAAATTCCAACATATTCTTGAATTGAAGAAACATATATCTGAAGATCACCCAAATCAACAACATaaatgcCCTCAATGTGGACAAATATTTGCACTTTCACAAGAAGTATCAGCACATATACGATCCTGTAAATTTGGATTATTAAACGAAATTTCTTCGCAAAATTCAAACATGTTTAAATGTTCAAAATGCTCCTACAAAACGAATTCTCAATCTGATTTAATCTTTCACGGAGTCTTACATGACAGTGTTGATagttcaaatgttataaaaactggaacaatgaaaaaatataagtgCCCAATGTGTCCAAAAATATTCAGAAAGGCTTCGTTGAGGTGTCATTTGAGAAAGCATACTTCGGAGAGACCGTATACTTGTGATGTTTGCCATGCAGGTTTCATTAGAAGATACAATTTGATGgaacataagaaaaatttacacAAAGATCAAGGACTATGCGATGAACTCAAGGATGATTATGAAGACCGACCGTTTTTGTGCGCTACTTGTGGGGCGAGTTTTAAaagaaagtaa
Protein Sequence: MDLSNDLEDDDDTHICLKCHTTIIGLDNYVSHRKNVRCKRKITETLKSEISIDPVVPTELPEYPLRADDFFSSLELQSSAKIAPSPRPPPGILTRSKTSAAILANSSQKELNERGNEWIGGHQLKVSGSDNHAKLIKAVDNISGNTIHKKEIHSTYQYDLDVDNFKNEIDSNDDYDDDEDEEDEDEDVPPRTHTGGKWKPRSSPIQWSGPSSSHVQSHDDLVGNDWYQNPPPSFTGGKWKPSLLGPAPIAPRRYDQDENNELSEDDENENKNTAPPPYHTKGKWIPGRQNEQMRKSYSQEKEMPSMLQYWCGLCNRMLASKTFYERHLKSNLHRKRCKKENELDSMYFEHAEKEVRPKRTRKAPKMFDEDIWDTDYTKTKKKNENIDFTEIRKVDPIIKCDVCRAKVHLHLIGKHLISHFHCRKGDRNHPMAMKMVLDNIHSVVFQSPFQCHPCRFYCNTQNTFMMHWSSESHLNCVEKTEGIYSCTFCNFECESTFHMFDHLQSEAHQEVVSVINRSMPIVIHKRSILHCNVCSQQFRYNIQLKQHCIKEGHVDHQHVAGKITQQKFECSECKSVFGRAIALQKHLHKRHSVLTYVCYICSLNFETSKAAKKHRSTLTHKYNAILKRIEKGLPVEDPSRNCMFCSKKFQHILELKKHISEDHPNQQHKCPQCGQIFALSQEVSAHIRSCKFGLLNEISSQNSNMFKCSKCSYKTNSQSDLIFHGVLHDSVDSSNVIKTGTMKKYKCPMCPKIFRKASLRCHLRKHTSERPYTCDVCHAGFIRRYNLMEHKKNLHKDQGLCDELKDDYEDRPFLCATCGASFKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01344550;
90% Identity: iTF_01344550;
80% Identity: -