Basic Information

Gene Symbol
-
Assembly
GCA_961205875.1
Location
OY540819.1:16824139-16825128[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0079 0.42 11.3 2.1 1 23 81 103 81 103 0.98
2 9 0.0013 0.07 13.8 0.8 1 23 109 131 109 131 0.98
3 9 0.00052 0.028 15.0 2.5 1 23 137 159 137 159 0.99
4 9 0.00049 0.026 15.1 0.6 1 23 165 187 165 187 0.98
5 9 0.0015 0.081 13.6 4.7 1 23 193 215 193 215 0.99
6 9 0.0012 0.063 13.9 1.0 1 23 221 243 221 243 0.97
7 9 0.0014 0.076 13.6 0.9 1 23 249 271 249 271 0.98
8 9 9.6e-06 0.00051 20.5 3.7 1 23 277 299 277 299 0.98
9 9 0.45 24 5.8 5.7 1 23 305 327 305 327 0.98

Sequence Information

Coding Sequence
ATGATTCgtataaaaacagaaaatattaaagaaGAGCTACAAGATGGTGAATTTGATCAAGAACAATCTATTTGTAAAGAAGAAATAGAGCAAAAAATTTCCTTCGAACAAGTTTATTTACCAGTATTTGTGAAAGAGGAATGCTGTTCAACCAACGAAAATGAGAGTAATTCTACATTTCAAGAAGGTGATGTATCTGAACTCTGTTCTAAAGTACAAACAAGTGATCAAGAACATCTGTATAAATGCGATCAGTGCGAATATGGCACTATTTATGAGTATAAATTGAAAACACATAAAATGAAACACGCTGgtaaacgaccttttaaatgcaatcgATGTGAATATAGCACCGTTACTTCAGCATTGTTGAATTTACATGAGAAGAATCACACATACGATAGACCATTTAAATGTGATGTATGTGGTTATAGATCCAAATGTAAGAGTGCTTTAATGATGCACATGATGACACACACTTGCGAAcgcccttttaaatgcaaccaatgtGAATTCACATCTACATTAAAAGGTACTTTAAAGGTGCATATGGCAATTCATACTTCTGAACGGCCTTACAAATGCGACGAATGTGATTATACAACAAGGTACAACATTTGTTTGAAACAACATAAAATGagacatactaatgaaagaccgtTTAAATGTAATTACTGTGAATTCAGTACAGTTGGGAAAAGTCTGTTAAAATTACATGAAATTAAACATACTAGCGAACTTCCTTACAAATGTGATCAATGTGAGTATAGCACCAATATTAAGGCCAATTTAACACTTCATGGGAAGAAACATTCAAGTGAGAAACCTTTTAGATGTGATATTTGTGAGTATAGTTGTAAAAGTAAAGGTAATTTGAAATCACACAAGAGAGTACATACCAGTGAATGCCCTTACAAATGCGATCAATgtgaatttaaaacaaaatgtaaGCAATATTTAAAACAACACATTATAAAGCATACGAAATGA
Protein Sequence
MIRIKTENIKEELQDGEFDQEQSICKEEIEQKISFEQVYLPVFVKEECCSTNENESNSTFQEGDVSELCSKVQTSDQEHLYKCDQCEYGTIYEYKLKTHKMKHAGKRPFKCNRCEYSTVTSALLNLHEKNHTYDRPFKCDVCGYRSKCKSALMMHMMTHTCERPFKCNQCEFTSTLKGTLKVHMAIHTSERPYKCDECDYTTRYNICLKQHKMRHTNERPFKCNYCEFSTVGKSLLKLHEIKHTSELPYKCDQCEYSTNIKANLTLHGKKHSSEKPFRCDICEYSCKSKGNLKSHKRVHTSECPYKCDQCEFKTKCKQYLKQHIIKHTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-