Sful002692.1
Basic Information
- Insect
- Sialis fuliginosa
- Gene Symbol
- znf423
- Assembly
- GCA_961205875.1
- Location
- OY540810.1:16177791-16183727[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 2.4e-05 0.0013 19.2 1.6 1 23 137 159 137 159 0.99 2 19 0.00018 0.0095 16.5 3.7 1 23 165 187 165 187 0.97 3 19 3.4e-06 0.00019 21.9 0.4 1 23 193 215 193 215 0.98 4 19 1.1e-05 0.00062 20.2 0.3 2 23 221 242 220 242 0.97 5 19 2.7e-05 0.0015 19.0 1.8 1 23 248 270 248 270 0.97 6 19 0.0002 0.011 16.3 1.6 1 23 280 303 280 303 0.97 7 19 3.8e-06 0.0002 21.7 2.3 2 23 310 331 309 331 0.97 8 19 0.00041 0.022 15.3 1.8 1 23 337 359 337 359 0.97 9 19 0.00051 0.028 15.0 6.5 1 23 365 388 365 388 0.96 10 19 0.01 0.55 10.9 0.1 3 21 396 414 395 415 0.92 11 19 0.0058 0.31 11.7 0.1 2 23 444 465 443 465 0.97 12 19 0.0094 0.5 11.1 1.6 1 23 471 494 471 494 0.95 13 19 0.0029 0.15 12.7 4.6 3 23 502 523 500 523 0.97 14 19 0.018 0.98 10.1 1.2 1 21 529 549 529 550 0.94 15 19 0.00076 0.041 14.5 0.9 1 23 557 579 557 579 0.96 16 19 0.00017 0.0094 16.5 0.8 2 23 586 607 585 607 0.94 17 19 0.0019 0.1 13.2 0.5 1 23 613 635 613 635 0.97 18 19 0.0014 0.073 13.7 7.4 1 23 641 663 641 663 0.97 19 19 0.00015 0.0081 16.7 4.2 1 23 669 692 669 692 0.96
Sequence Information
- Coding Sequence
- aTGGAAATTTCAACACTTAATTCCAAATCTGTCGATAAAGCCTGTAGAGTTTGCTTATTAGATAAAGGGAATAATGTAAGATCTATATTTGAGGTAATTACTCTGGAAATTCAGGACATCAGTGTTGATAAAATTCTAATGGAATGCGCTTCTGTAAAAGTAAAAGCACAGGATGAATTTTCAAAGCGTATTTGTGATATATGTTTCGTACAAGCCAAAATTGCATACGAGTTTCgacaaaaatgcaaaaaatcggAAACATTACTGATTGAgtatcaaagaaaaaaaaacgaggTTCAAAACACGGCAAAAGATGAATCGTTCATGGATGATTTCAATGACACAATCAGTAGTGATGATGATTCAAGCTATAGCATCGAAAATAACGAAGCTAAAGAAGCAAAACAATACAAATGTAACTATTGCAATAAAGAATTTGAAAAGGAAACTTCACTGGCCGTACATAGAAAGAGCCATACAGGTGCTAAACGACACATTTGTACAGAGTGCAATAAAGAATTCATGACGTCACAtcgtttaaaaatacatattcgtattcacacagGGGAAAGACCATTTTCTTGTGCTCAGTGCGACAAACAATTTGCTACAAAGGGAAACTTGGCAACTCATCTTCGACTCCACAGTGAATACCGACTTAAATGTGAAGTTTGCgGTGAAACGTTTCAACAGCAAGTTGCATTAAAAGCCCATCGCAAAAGTCACAAAGAAGCACAAGAACACATTTGTGGTCATTGTGGAAAGGAGTTTATGGGGGcgtatcaattaaaaaaacatgtccGTGTTCATGTTGGCCTAGCTAcagatgaaaagtatttttcttgttttaaaTGCGAAGAGAAGTTTACCAAAAGCACTGAACTAATGAAACACGTTCTTACCGAACATTCCGTTGGGAATTCGTTACAATGTCATTTTTGcgGTGAAACGTTTAAAAAACGTGGAGAGTTACAAATTCACTTAAAAACTCACACCGGAGCTAAACGACACGTTTGTGATCGATGCGGTAAAGAGTTCCTCAGCCGATATAAGTTAACTGTTCACATGATGTCTCATTtagGTGAAAGACCATTCGAATGTAAACACTGTGATAGAAAATTCAAAGAGCGTAACAGCTTGAGGCACCACGAACGTTTACAGCACGGTTTGGGTGATGGAGGGCATTGTCCCGGTTGCAAGATGACGTTTGCAACAGCTAAAGCTCTTGACCAACACACCGCAACTTGCTCGGTACGCCGTAATGTCTCTCCGACGGATATATCTCCGGATATAGTTATTCCTAATGCGTGTGATGATTCTTCTAGTGTCAAATGTAGATTCTgtgGTTTGGTTTTTGAAAAACCTGGACCATTAAGAATCCATGAAAAAATCCATACAGGCGCAAAACGACATATTTGTGAAATATGTGGTTTGGAGTGTATGGACAATTATAAACTCACCGTTCATAAAATGAAAGCTCATACGGGTGAAAAACCATTTTGGTGCCAGCAATGTGATAAACGTTTCCACGAGAAGACCCGCCTGCAGCACCACATGCGAGTAGCGCATGGACTGGCCGAGGGGTTCCAGTGTGAGAAGTGCAAAAAGTGGTTCAAGCGCACAGAACTGCTTGACCGGCACGCAAAGAAATGCGCAGGGGCCAAACCCCACGCATGCTCTCACTGTCCTGTGAGGTTCGACTCTGCGTTTGGGCTCGAGATGCATCTCAGAATACATACAGGTATTCGGCCGTTCCTGTGCCGAGCGTGCGGTAAAGGGTTCAAAAGGAAACAAACGCTGGCAGAGCACGAGAGGACGCATACGGGAGAGAGGCCCCACCAGTGCGACCAATGCGCCAGGGCGTTCATGCGCAGGGTTGAACTGGTCATACACCAGCAGGAACATACGGGGATATACCCGCACGTGTGCCATATTTGTGGAAAGACATTTAAATGTTCGAGTGGATTGAGTCGACACAAAAGTACCCATTCTAAAGAACGGCCGTACGTGTGCCGTATCTGCTTCAAAACGTTCAGTCGTACAGACGGTTTACGAAGGCACACAAATAATTGTCACCCAAAACAAAACTGGTCGGATAACTCAAACACTTACCaaaaGACTGAAAATACAAGTTTGGAGACCTGGTGTCCGACAAGAAACGGAAAtgaaaatatatcgtaa
- Protein Sequence
- MEISTLNSKSVDKACRVCLLDKGNNVRSIFEVITLEIQDISVDKILMECASVKVKAQDEFSKRICDICFVQAKIAYEFRQKCKKSETLLIEYQRKKNEVQNTAKDESFMDDFNDTISSDDDSSYSIENNEAKEAKQYKCNYCNKEFEKETSLAVHRKSHTGAKRHICTECNKEFMTSHRLKIHIRIHTGERPFSCAQCDKQFATKGNLATHLRLHSEYRLKCEVCGETFQQQVALKAHRKSHKEAQEHICGHCGKEFMGAYQLKKHVRVHVGLATDEKYFSCFKCEEKFTKSTELMKHVLTEHSVGNSLQCHFCGETFKKRGELQIHLKTHTGAKRHVCDRCGKEFLSRYKLTVHMMSHLGERPFECKHCDRKFKERNSLRHHERLQHGLGDGGHCPGCKMTFATAKALDQHTATCSVRRNVSPTDISPDIVIPNACDDSSSVKCRFCGLVFEKPGPLRIHEKIHTGAKRHICEICGLECMDNYKLTVHKMKAHTGEKPFWCQQCDKRFHEKTRLQHHMRVAHGLAEGFQCEKCKKWFKRTELLDRHAKKCAGAKPHACSHCPVRFDSAFGLEMHLRIHTGIRPFLCRACGKGFKRKQTLAEHERTHTGERPHQCDQCARAFMRRVELVIHQQEHTGIYPHVCHICGKTFKCSSGLSRHKSTHSKERPYVCRICFKTFSRTDGLRRHTNNCHPKQNWSDNSNTYQKTENTSLETWCPTRNGNENIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01344215;
- 90% Identity
- iTF_01344215;
- 80% Identity
- -