Basic Information

Insect: Shargacucullia verbasci
Gene Symbol: Ctcfl
Assembly: GCA_947562105.1
Location: OX387279.1:18697298-18707411[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0051 0.39 11.6 5.9 1 23 307 329 307 329 0.98

2 11 7.7e-05 0.0058 17.3 1.1 1 23 335 357 335 357 0.98

3 11 7.5e-05 0.0056 17.3 1.7 1 23 363 386 363 386 0.96

4 11 0.035 2.7 8.9 3.2 1 21 392 412 392 414 0.95

5 11 0.00011 0.0084 16.8 2.7 1 23 420 442 420 442 0.99

6 11 1.5e-05 0.0011 19.5 5.3 1 23 448 470 448 470 0.98

7 11 0.0034 0.26 12.1 0.9 1 23 478 501 478 501 0.97

8 11 0.018 1.4 9.8 4.3 2 23 508 529 507 529 0.96

9 11 0.00036 0.027 15.2 2.5 1 23 535 557 535 557 0.98

10 11 2.6e-06 0.0002 21.9 1.7 1 23 563 586 563 586 0.96

11 11 1.2e-05 0.00087 19.9 4.4 1 23 600 622 600 622 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0051	0.39	11.6	5.9	1	23	307	329	307	329	0.98
2	11	7.7e-05	0.0058	17.3	1.1	1	23	335	357	335	357	0.98
3	11	7.5e-05	0.0056	17.3	1.7	1	23	363	386	363	386	0.96
4	11	0.035	2.7	8.9	3.2	1	21	392	412	392	414	0.95
5	11	0.00011	0.0084	16.8	2.7	1	23	420	442	420	442	0.99
6	11	1.5e-05	0.0011	19.5	5.3	1	23	448	470	448	470	0.98
7	11	0.0034	0.26	12.1	0.9	1	23	478	501	478	501	0.97
8	11	0.018	1.4	9.8	4.3	2	23	508	529	507	529	0.96
9	11	0.00036	0.027	15.2	2.5	1	23	535	557	535	557	0.98
10	11	2.6e-06	0.0002	21.9	1.7	1	23	563	586	563	586	0.96
11	11	1.2e-05	0.00087	19.9	4.4	1	23	600	622	600	622	0.97

Sequence Information

Coding Sequence: ATGGAAATAGGCACGGTGTTAAAAATTAAACTTATTTATCTTGATGATTTTATTGTCTTCTACAGGCTGGCAGGCTCAGAAAGCCGTGCAAATCACGCAAGCCAGGAAAACTTGGCAGGCCAGGAGACCGAGCGAAACCTGGCAAGCCAAGTTAATCTGGCAAGCCAGTATATTACTTCGGGCGGCCTAGTAACTCCGGCCACTCAGAAGTCCGCAATAGCCCAGAAAACAAAGAAAAACCTGAGAAGCCAAAATAGTCCACTAGAAGATCAGGAAAGCAAAGATACTCGACCAGACAGTTTGGTGTTTGTGGAGAAGAAACCTGACCAGCATAGCCTAATTACTGAGGAAGCGACCATGCCGCCCCCAGATAAAAAGGATAAGACCAAGCAAACCCTCATACAGTCGTATTTGAATCAAGATGCCACAGCTACAGTTATCGCAGTCAATGGGGCGGCGGACGATGAAACCGATACCTCCGGAGTCACGTACTTCGTGGATGAGGAAGGCCGGTACTACTACCAATCTGCAGGCGACACTTCGAACCTCGTTTCCATATCTGGGACGGGAGTGAGTGATGATAACGAGGGTATGGGTGAAGATGAACAGATGATGGCCTCGCCGGGGACCGAGAGCTATCAGACTGTCACCCTCGTGCCTTCGGAGACAAGCAATGGGGAAGTCAGCTACGTATTGGTGGTACAGGAAGAGAGCAAGCCCGTTGTCAACATTGATATCAATGTGGATTCGGCTAATCAAGAGGACAAAGGCAACGACGATGTGTACAACTTCGATGATGAAGAGGAAGGTGGAGAGCCACCTACGGAGGAGGAAGACGACCCCGTCAGCAACGTCATCGAGACGCCGGGCCTCAAGATGAAGCCTCCCAGGTCCCGAGTGAAGAACGTGCGTCCACAGTTCACCTGCAATTTCTGCTCCTACACTAGTCATCGCCGCTACCTGCTGCTCCGCCACATGAAGTCTCACTCGGAGGATCGCCCGCACAAGTGTAGCGTGTGTGAGCGTGGCTTCAAGACCATCGCCTCCCTGCAGAACCACGTCAACATGCACAACGGCGTCAAACCGCATGTGTGCAAGTATTGCAACAGCCCATTCACTACCTCTGGTGAGCTGGTCAGGCACGTCCGCTACAAGCATACGCATGAGAAGCCTCACAAGTGCTCCGAGTGTGACTATGCGTCCGTCGAGCTGTCCAAGCTTCGGCGGCATGTGCGCTGCCACACCGGCGAGAGGCCGTATCAGTGCCCTCACTGCACCTACGCTTCTCCGGACACGTTCAAGTTGAAGCGTCACCTGCGCACGCACACCGGCGAGAAGCCGTACAAGTGCGAGCACTGCAACATGTGCTTCACGCAGTCCAACTCATTGAAGGCACACAGACTGATCCACAACGTGTCGGAGAAGCCGGTATACTCTTGCGAGCTGTGCCCGGCCAAGTGCGGCCGTAAGACTGACCTGCGGATTCACGTGCAGAAGTTGCACACGTCAGACAAGCCGCTCAAGTGCCGCCGCTGCGGGAAGTCCTTCCCCGACCGATACTCCTGCAAGGTGCACAATAAGACGCATGAAGGCGAGAAGTGCTTCAAGTGCGAGCTGTGTCCGTACGCGTCAACCACGATGCGCCATCTCAAGTCGCATATGCTCAAGCACACTGATGAGAAGCCGTTCGTATGCGATATGTGCGACCAGTCTTTCAGGCAAAAACAGCTGCTCCGCCGCCACCAAAACCTCTACCACAATCCCGACTACGTGCCAAAGCCGCCCAAAGAGAAGACACACACCTGCCATGAGTGCAAGCGCATGTTCGCGCACAAGGGCAACCTGATCCGCCATCTGGCTGTCCACGATCCTGAGTCGGGCCACCACGAGCGGGCCTTGGCCCTCAAGATCGGACGCCAGCGGAAGGTCAAGTTCATCGATGGACAGCTCATGAAGGATATTCGCAACATTGAGACCGAAGAAGGAACCGATCTGATGAAGCTAGGTCTCAGCAATAACGAGCTAAAGCGCGGCGAGCTGGTCACCGTGGCCGACGGCGACGGCCAGCAGTACGTGGTGCTGGAGGTCATTCAGCTGGAGGACGGCACCGAACAACAGGTCGCTGTCGTCGCGCCCGACTACATGGAGGAGGATGAAGCAGAAGAGGAAGAGGAGGAGGAAGAAGAGGAAGAGGAAGAGCCGGTAGAGAAGAAGTACATAGTGAAGGAGACAGAAACTGAGCGGAGTATCAAAGTGGAGAAGGACGTCGACACCTGCTTCGGGTTTGACGAGGAAGAAGAGGAGGACGGAGAAGATGAGGGTATACCTGAGAAAGTCGTTTTTCATATAGTTTAG
Protein Sequence: MEIGTVLKIKLIYLDDFIVFYRLAGSESRANHASQENLAGQETERNLASQVNLASQYITSGGLVTPATQKSAIAQKTKKNLRSQNSPLEDQESKDTRPDSLVFVEKKPDQHSLITEEATMPPPDKKDKTKQTLIQSYLNQDATATVIAVNGAADDETDTSGVTYFVDEEGRYYYQSAGDTSNLVSISGTGVSDDNEGMGEDEQMMASPGTESYQTVTLVPSETSNGEVSYVLVVQEESKPVVNIDINVDSANQEDKGNDDVYNFDDEEEGGEPPTEEEDDPVSNVIETPGLKMKPPRSRVKNVRPQFTCNFCSYTSHRRYLLLRHMKSHSEDRPHKCSVCERGFKTIASLQNHVNMHNGVKPHVCKYCNSPFTTSGELVRHVRYKHTHEKPHKCSECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCEHCNMCFTQSNSLKAHRLIHNVSEKPVYSCELCPAKCGRKTDLRIHVQKLHTSDKPLKCRRCGKSFPDRYSCKVHNKTHEGEKCFKCELCPYASTTMRHLKSHMLKHTDEKPFVCDMCDQSFRQKQLLRRHQNLYHNPDYVPKPPKEKTHTCHECKRMFAHKGNLIRHLAVHDPESGHHERALALKIGRQRKVKFIDGQLMKDIRNIETEEGTDLMKLGLSNNELKRGELVTVADGDGQQYVVLEVIQLEDGTEQQVAVVAPDYMEEDEAEEEEEEEEEEEEEPVEKKYIVKETETERSIKVEKDVDTCFGFDEEEEEDGEDEGIPEKVVFHIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00050186;
90% Identity: iTF_00050186;
80% Identity: -